He aha ka Lapaʻau Kūpono no ka Maʻi Kānaka o ka Umauma? Ke Kumu, ke Kaʻina Hana & nā Hōʻike

ʻO ka lapaʻau kūpono no ka maʻi kānaka o ka umauma he ala pilikino e hoʻohana ana i ke ʻano genetic o kāu ʻōpū e alakaʻi i nā hoʻoholo lapaʻau. Ma kahi o ka hoʻohana ʻana i kahi hoʻolālā lapaʻau hoʻokahi, e nānā nā kauka i nā ʻano kikoʻī o kāu mau pūnaewele maʻi kānaka e koho i nā lāʻau lapaʻau e hana maikaʻi loa iā ʻoe.

Hōʻike kēia ala i kahi hoʻololi nui mai ka lapaʻau maʻi kānaka kuʻuna. E nānā ana kāu hui lapaʻau i ka DNA o kāu maʻi kānaka a i kekahi manawa i kāu ʻano genetic ponoʻī e hana i kahi hoʻolālā lapaʻau i hana kūikawā ʻia i kāu kūlana. E noʻonoʻo e like me ka loaʻa ʻana o kahi blueprint kikoʻī o kāu maʻi kānaka e kōkua ana i nā kauka e koho i nā mea kaua maikaʻi loa e hakakā ai.

He aha ka lapaʻau kūpono no ka maʻi kānaka o ka umauma?

ʻO ka lapaʻau kūpono no ka maʻi kānaka o ka umauma he ala lapaʻau e nānā ana i nā hiʻohiʻona molekala a me ka genetic o kāu ʻōpū kikoʻī. Hoʻohana kāu kauka i kēia ʻike e koho i nā lāʻau lapaʻau i manaʻo ʻia e hana pono i kāu ʻano maʻi kānaka o ka umauma.

Hele kēia hana ma mua o ka nānā ʻana i ka nui a me kahi o kāu ʻōpū. Ma kahi o, nānā ia i nā pūnaewele maʻi kānaka ma lalo o ka microscope a holo i nā hoʻokolohua genetic e hoʻomaopopo i ke ʻano o ka ulu ʻana a me ka laha ʻana o kāu maʻi kānaka. ʻO ka pahuhopu e hoʻohālikelike iā ʻoe me nā lāʻau lapaʻau e kuhikuhi ana i nā ala kikoʻī e hoʻohana ai kāu maʻi kānaka e ola a hoʻonui.

Hana ke ʻano genetic o kāu maʻi kānaka e like me ka manamana lima i kū hoʻokahi i kāu ʻōpū. Hilinaʻi kekahi mau maʻi kānaka o ka umauma i nā hormones e like me ka estrogen e ulu ai, aʻo nā mea ʻē aʻe he nui loa ka protein i kapa ʻia ʻo HER2. Loaʻa i nā mea ʻē aʻe nā mutations genetic kikoʻī e hoʻomaikaʻi ai lākou i kekahi mau lāʻau. Ma ka ʻike ʻana i kēia mau ʻano, hiki i kāu hui lapaʻau ke koho i nā lāʻau lapaʻau e hoʻouka i nā wahi nāwaliwali o kāu maʻi kānaka.

No ke aha e hana ʻia ai ka lapaʻau kūpono no ka maʻi kānaka o ka umauma?

Kōkua ka lāʻau lapaʻau pololei i nā kauka e koho i nā lāʻau lapaʻau maikaʻi loa me ka pale ʻana i nā lāʻau lapaʻau i ʻole e hana no kāu maʻi maʻi kikoʻī. Hiki i kēia ala ke hoʻomaikaʻi i nā hopena o kāu mālama ʻana a hoʻemi i nā hopena ʻaoʻao pono ʻole mai nā lāʻau lapaʻau ʻaʻole e pōmaikaʻi iā ʻoe.

ʻO ka mālama ʻana i ka maʻi maʻi umauma kuʻuna e pili pinepine ana i ka hoʻāʻo ʻana i nā lāʻau lapaʻau maʻamau a me ka ʻike ʻana i ke ʻano o kāu pane ʻana. Me ka lāʻau lapaʻau pololei, hiki i nā kauka ke wānana i nā lāʻau lapaʻau e hana nui ana ma mua o kou hoʻomaka ʻana iā lākou. Mālama kēia i ka manawa waiwai a kōkua iā ʻoe e pale i ka pilikia kino a me ka naʻau o nā lāʻau lapaʻau pono ʻole.

Hiki i ka ʻikepili genetic o kāu maʻi maʻi ke kōkua i ka wānana ʻana i ke ʻano o ka hana ʻino ʻana a inā paha e hoʻi mai ma hope o ka mālama ʻana. Kōkua kēia ʻike i kāu hui lapaʻau e hoʻomohala i kahi hoʻolālā lapaʻau piha e pili ana ʻaʻole wale i kāu maʻi maʻi i kēia manawa, akā hana pū kekahi e pale i ka hana hou ʻana i ka wā e hiki mai ana.

He aha ke kaʻina hana no ka hoʻāʻo ʻana i ka lāʻau lapaʻau pololei?

Hoʻomaka ka hoʻāʻo ʻana i ka lāʻau lapaʻau pololei me ka nānā ʻana i kahi laʻana o kāu ʻiʻo tumora, i loaʻa maʻamau i ka wā o kāu biopsy a i ʻole ke ʻoki ʻana. Nānā ka hale hana i kēia ʻiʻo me ka hoʻohana ʻana i nā ʻenehana hoʻāʻo genetic holomua e ʻike i nā loli kikoʻī a me nā ʻano o kāu mau cell maʻi maʻi.

E hōʻiliʻili mua kāu kauka i kahi laʻana ʻiʻo inā ʻaʻole i loaʻa mai kāu hōʻailona mua. Hele kēia laʻana i kahi hale hana kūikawā kahi e unuhi ai nā technicians i ka DNA a me ka RNA mai kāu mau cell maʻi maʻi. A laila, holo lākou i nā hoʻokolohua genetic piha, i kapa pinepine ʻia ʻo ka profiling tumor a i ʻole ka genomic sequencing, e ʻike i nā loli kikoʻī a me nā pae protein.

ʻO ka hana hoʻāʻo e pili ana i kekahi mau loiloi nui e kōkua i ka pena ʻana i kahi kiʻi piha o kāu maʻi maʻi:

• Ka hoʻāʻo ʻana i nā mea loaʻa hormone e ʻike ai inā e ulu ana kāu maʻi maʻi i ka pane ʻana i ka estrogen a i ʻole ka progesterone
• Ka hoʻāʻo ʻana i ka protein HER2 e hoʻoholo ai inā he nui loa kēia protein hoʻoulu ulu i kāu maʻi maʻi
• Ka loiloi hoʻololi genetic e ʻimi ai i nā loli kikoʻī i nā genes pili i ka maʻi maʻi
• Ka hoʻāʻo ʻana i ka ukana mutation tumor e ʻike ai i ka nui o nā loli genetic i loaʻa i kāu maʻi maʻi
• Ka hoʻāʻo ʻana i ka microsatellite instability e nānā ai i nā pilikia hoʻoponopono DNA

ʻO ka hana hoʻāʻo holoʻokoʻa e lawe maʻamau i hoʻokahi a ʻelua pule, ʻoiai e loaʻa ana kekahi mau hopena i ka wā ma mua. E nānā kāu hui lapaʻau i nā hopena a pau e hana i kāu hoʻolālā lapaʻau pilikino.

Pehea e hoʻomākaukau ai no ka hoʻāʻo ʻana i ka lāʻau lapaʻau pololei?

ʻO ka hapa nui o ka hoʻāʻo ʻana i ka lāʻau lapaʻau pololei e koi i ka ʻiʻo i hōʻiliʻili mua ʻia i ka wā o kāu biopsy a i ʻole ke ʻoki ʻana, no laila ʻaʻole pono ʻoe i ka hoʻomākaukau kūikawā. Eia naʻe, pono paha i kāu kauka ke kiʻi i nā laʻana ʻiʻo hou inā ʻaʻole kūpono ka laʻana kumu no ka hoʻāʻo piha.

Inā pono ʻoe i kahi laʻana ʻiʻo hou, e wehewehe kāu hui lapaʻau i ke kaʻina hana kikoʻī a me nā hoʻomākaukau e pono ai. Hiki i kēia ke komo i kahi biopsy nila a i ʻole kahi hana ʻoki liʻiliʻi, ma muli o ka wahi a me ke komo ʻana o kāu maʻi maʻi.

Ma mua o ka hoʻomaka ʻana o ka hoʻāʻo ʻana, he mea kōkua ke hōʻiliʻili i ka ʻike e pili ana i ka mōʻaukala o kou ʻohana i ka maʻi maʻi, ʻo ia hoʻi ka umauma, ka ovarian, a me nā maʻi maʻi ʻē aʻe. Hiki i kēia ʻike ke kōkua i kāu ʻōlelo aʻoaʻo genetic a me ka oncologist e wehewehe pololei i nā hopena o kāu hoʻāʻo. Hiki nō hoʻi iā ʻoe ke hoʻomākaukau i nā nīnau e pili ana i ka mea e hōʻike ʻia e ka hoʻāʻo ʻana a pehea e pili ai i kāu mau koho lapaʻau.

Pehea e heluhelu ai i kāu mau hopena lāʻau lapaʻau pololei?

E ʻike kāu hōʻike lāʻau lapaʻau pololei i nā loli genetic kikoʻī, nā pae protein, a me nā ʻano ʻē aʻe o kāu mau cell maʻi maʻi. E wehewehe kāu oncologist i ke ʻano o kēlā me kēia ʻike no kāu mau koho lapaʻau a me ka prognosis.

ʻO ka hōʻike maʻamau e komo pū ana i ka ʻike e pili ana i nā mea hoʻokipa hormone, e haʻi ana iā ʻoe inā e ulu ana kāu maʻi maʻi i ka pane ʻana i ka estrogen a i ʻole progesterone. Inā he hormone receptor-positive kāu maʻi maʻi, e pōmaikaʻi paha ʻoe mai nā lapaʻau e pale ana i ka hormone. Inā he hormone receptor-negative, ʻaʻole e pono kēia mau lapaʻau iā ʻoe.

ʻO ke kūlana HER2 kekahi mea nui i kāu hōʻike. Ma kahi o 20% o nā maʻi maʻi umauma he nui loa ka protein HER2, e hoʻonui ana iā lākou. Eia naʻe, pane maikaʻi kēia mau maʻi maʻi i nā lāʻau i manaʻo ʻia e like me ka trastuzumab (Herceptin) e ālai pono ana iā HER2.

Hiki nō hoʻi i kāu hōʻike ke ʻike i nā loli genetic kikoʻī e pili ana i nā koho lapaʻau. ʻO kekahi mau loli e hoʻonui i ka hiki ʻana o nā maʻi maʻi e pane i kekahi mau lāʻau chemotherapy a i ʻole nā lāʻau i manaʻo ʻia. Hōʻike paha nā mea ʻē aʻe i ka piʻi a i ʻole ka emi ʻana o ka pilikia o kāu maʻi maʻi e laha a i ʻole e hoʻi mai ma hope o ka lapaʻau.

ʻO ka ukana mutation tumor, a i ʻole TMB, e haʻi iā ʻoe i ka nui o nā loli genetic i loaʻa i kāu maʻi maʻi. Pane maikaʻi kekahi mau maʻi maʻi me ka TMB kiʻekiʻe i nā lapaʻau immunotherapy e kōkua ana i kāu ʻōnaehana pale e hakakā i ka maʻi maʻi. E wehewehe kāu kauka i ke ʻano o kēia ʻike i kāu kūlana.

Pehea e hoʻomaikaʻi ai i kāu lapaʻau lāʻau lapaʻau pololei?

ʻO ka hana pili pū me kāu hui oncology e hōʻoiaʻiʻo ana e loaʻa iā ʻoe ka pōmaikaʻi nui mai nā ala lāʻau lapaʻau pololei. Pono e nānā mau ʻia kāu hoʻolālā lapaʻau a hoʻoponopono ʻia ma muli o ke ʻano o ka pane ʻana o kāu maʻi maʻi a me nā hopena hoʻāʻo hou.

E noho ikaika i kāu mau hoʻoholo lapaʻau ma ka nīnau ʻana i nā nīnau e pili ana i ke kumu i ʻōlelo ʻia ai nā lāʻau lapaʻau kikoʻī no ke ʻano genetic o kāu maʻi maʻi. ʻO ka hoʻomaopopo ʻana i ke kumu o kāu hoʻolālā lapaʻau hiki ke kōkua iā ʻoe e manaʻoʻiʻo a komo i kāu mālama.

E noʻonoʻo e komo i nā hoʻokolohua lapaʻau e kūlike me nā ʻano genetic o kāu maʻi kanesa. Nui nā lāʻau lapaʻau pololei i loaʻa mua ma o nā hoʻokolohua lapaʻau, a ʻo ke komo ʻana e hāʻawi iā ʻoe i ke komo ʻana i nā lāʻau lapaʻau kiʻekiʻe ʻaʻole i loaʻa ākea.

E mālama i nā moʻolelo kikoʻī o kāu mau pane lapaʻau a me nā hopena ʻaoʻao āu e ʻike ai. Kōkua kēia ʻike i kāu hui lapaʻau e hoʻoponopono i kāu hoʻolālā lapaʻau a hana i nā hoʻoponopono e like me ka mea e pono ai. Hoʻopili kekahi mau ala lapaʻau pololei i ka hoʻololi ʻana ma waena o nā lāʻau lapaʻau i manaʻo ʻia e pili ana i ka pane ʻana o kāu maʻi kanesa i ka manawa.

He aha ke ala lapaʻau pololei maikaʻi loa?

ʻO ke ala lapaʻau pololei maikaʻi loa e hilinaʻi loa i nā ʻano genetic kikoʻī o kāu maʻi kanesa a me kou kūlana olakino holoʻokoʻa. ʻAʻohe lāʻau lapaʻau hoʻokahi

Hiki i kekahi mau mea ke hoʻemi i ka pono o nā lāʻau lapaʻau lapaʻau pololei, akā hiki ke mālama ʻia ka nui o kēia mau mea me ka nānā pono ʻana a me ka hoʻoponopono ʻana i ka lāʻau. ʻO ka hoʻomaopopo ʻana i kēia mau mea pilikia e kōkua i kāu hui lapaʻau e hoʻomaikaʻi i kāu hoʻolālā lapaʻau.

Hiki i nā sela maʻi ʻaʻai ke kūʻē i nā lāʻau lapaʻau i manaʻo ʻia i ka manawa ma ka loaʻa ʻana o nā loli hou a i ʻole ka loaʻa ʻana o nā ala ulu ʻē aʻe. ʻO ia ke kumu e ʻōlelo ai kāu kauka e hana hou i ka hoʻāʻo ʻana i kāu maʻi ʻaʻai e ʻike inā ua loli kona ʻano genetic i ka wā o ka mālama ʻana.

Nui nā mea e hiki ke hoʻopilikia i ka maikaʻi o nā lāʻau lapaʻau pololei no ʻoe:

• ʻO ka chemotherapy mua a i ʻole nā lāʻau lapaʻau radiation i hiki ke hoʻoulu i nā loli genetic hou i kāu maʻi ʻaʻai
• ʻO nā kūlana olakino holoʻokoʻa e pili ana i ke ʻano o kou kino e hana ai i nā lāʻau lapaʻau
• ʻO ke kahua a me ka nui o kāu maʻi ʻaʻai i ka wā e hoʻomaka ai ka lāʻau lapaʻau pololei
• Pehea ka wikiwiki o ka ulu ʻana a me ka laha ʻana o kāu maʻi ʻaʻai
• Ka loaʻa ʻana o nā loli genetic he nui e paʻakikī ai ke koho ʻana i ka lāʻau lapaʻau

E hana kāu hui lapaʻau e hōʻemi i kēia mau mea pilikia a hoʻoponopono i kāu hoʻolālā lapaʻau e like me ka mea e pono ai. He mea nui ka nānā mau ʻana a me ke kamaʻilio ʻana me kāu mau mea mālama ola kino no ka mālama ʻana i ka pono o nā ala lapaʻau pololei.

ʻOi aku ka maikaʻi o ka loaʻa ʻana o nā loli i manaʻo ʻia a i ʻole nā mea i manaʻo ʻole ʻia?

ʻO ka loaʻa ʻana o nā loli i manaʻo ʻia i loko o kāu maʻi ʻaʻai umauma i manaʻo ʻia he mea maikaʻi no ka mea, ʻo ia hoʻi, aia nā lāʻau lapaʻau i hoʻolālā ʻia e hoʻouka i kēlā mau loli genetic. Eia naʻe, hiki ke mālama maikaʻi ʻia nā loli i manaʻo ʻia a me nā mea i manaʻo ʻole ʻia me nā ala lapaʻau pololei o kēia manawa.

ʻO nā hoʻololi genetic i hiki ke kuhikuhi ʻia, he mau loli genetic i hana ʻia e nā ʻepekema i nā lāʻau lapaʻau kūikawā. No ka laʻana, inā he PIK3CA mutation kāu maʻi maʻi, hiki iā ʻoe ke pōmaikaʻi mai nā lāʻau lapaʻau e like me ka alpelisib e kuhikuhi pono ana i kēia ala. ʻO kēia mau lāʻau lapaʻau i kuhikuhi ʻia e hana pinepine i nā hopena ʻaoʻao liʻiliʻi ma mua o ka chemotherapy kuʻuna ʻoiai e pono ai i ka maʻi maʻi kikoʻī.

ʻAʻole i loaʻa i nā hoʻololi ʻaʻole hiki ke kuhikuhi ʻia nā lāʻau lapaʻau kūikawā i hoʻolālā ʻia no lākou, akā ʻaʻole kēia manaʻo he palena kāu mau koho lapaʻau. Hiki i kāu hui lapaʻau ke hoʻohana i kēia ʻike genetic e alakaʻi i nā hoʻoholo lapaʻau, e like me ke koho ʻana i nā lāʻau chemotherapy e hana maikaʻi ana i nā maʻi maʻi me kekahi mau hiʻohiʻona mutation.

Ke ulu wikiwiki nei ke kahua o ka lāʻau lapaʻau pololei, a ke hoʻomau nei nā mea noiʻi i ka hoʻomohala ʻana i nā lāʻau lapaʻau hou i kuhikuhi ʻia. ʻO ka mutation i manaʻo ʻia ʻaʻole hiki ke kuhikuhi ʻia i kēia lā, hiki ke loaʻa nā lāʻau lapaʻau kūikawā i ka wā e hiki mai ana. E mālama kāu oncologist iā ʻoe i ka ʻike e pili ana i nā koho lapaʻau hou e loaʻa ana no ka ʻikepili genetic o kāu maʻi maʻi.

He aha nā pilikia hiki ke loaʻa i ka lāʻau lapaʻau pololei?

Hiki i nā lāʻau lapaʻau pololei ke hana i nā hopena ʻaoʻao, ʻoiai ua maʻalahi lākou ma mua o nā hopena ʻaoʻao chemotherapy kuʻuna. E nānā pono kāu hui lapaʻau iā ʻoe a hoʻoponopono i nā lāʻau lapaʻau e like me ka mea e pono ai e hōʻemi i nā pilikia.

Hiki i nā lāʻau lapaʻau i kuhikuhi ʻia ke hana i nā hopena ʻaoʻao e pili ana i nā protein a i ʻole nā ala a lākou e ālai ai. No ka laʻana, hiki i nā lāʻau lapaʻau i kuhikuhi ʻia e HER2 ke hoʻopilikia i ka hana o ka naʻau, ʻoiai ʻo nā lāʻau lapaʻau e ālai ana i ka hormone e hana i nā hōʻailona menopausal a i ʻole ka lahilahi o ka iwi. E nānā kāu kauka i kēia mau hopena a hāʻawi i ka mālama kākoʻo e like me ka mea e pono ai.

Hiki i kekahi mau lāʻau lapaʻau pololei ke hana i nā pilikia e pono ai ka mālama pono:

• Nā hopena ʻili e like me ka ʻōpala a i ʻole ka maʻalahi i ka lā mai kekahi mau lāʻau lapaʻau i manaʻo ʻia
• Ka maʻi palahī a i ʻole nā pilikia digestive mai kekahi mau lāʻau lapaʻau i manaʻo ʻia
• Nā loli i nā helu koko e koi ai i ka hoʻoponopono ʻana i ka dosis a i ʻole nā hoʻomaha lapaʻau
• Nā loli hana ate e pono ai ka nānā ʻana me nā hoʻokolohua koko maʻamau
• Luhi a i ʻole nāwaliwali e pili ana i kāu mau hana i kēlā me kēia lā

Hiki ke mālama ʻia ka hapa nui o nā hopena ʻaoʻao mai nā lāʻau lapaʻau lāʻau lapaʻau me ka mālama kākoʻo a me nā hoʻoponopono dosis. E hana pū kāu hui lapaʻau me ʻoe e ʻimi i ke kaulike kūpono ma waena o ka lapaʻau kūpono a me ka maikaʻi o ke ola.

He aha nā pilikia hiki ke loaʻa o ka lāʻau lapaʻau pololei ʻole?

Me ka ʻole o nā ala lāʻau lapaʻau pololei, hiki iā ʻoe ke loaʻa nā lāʻau lapaʻau i ʻoi aku ka liʻiliʻi o ka hopena no kāu ʻano maʻi maʻi umauma. Hiki i kēia ke alakaʻi i nā pane lapaʻau i hoʻopaneʻe ʻia, nā hopena ʻaoʻao pono ʻole, a me nā hopena maikaʻi ʻole.

ʻO ka hoʻohana ʻana i kahi ala hoʻokahi-nui-kūpono, ʻo ia hoʻi, hiki iā ʻoe ke nalo i nā lāʻau lapaʻau i manaʻo ʻia e hana maikaʻi no kāu ʻano genetic maʻi maʻi. No ka laʻana, inā loaʻa i kāu maʻi maʻi ka HER2 overexpression akā ʻaʻole i ʻike ʻia kēia, ʻaʻole paha ʻoe e loaʻa nā lāʻau lapaʻau i manaʻo ʻia e HER2 e hiki ke hoʻomaikaʻi nui i kāu hopena.

Hiki i ka lāʻau lapaʻau pololei ʻole ke hopena i nā hopena hopohopo:

• Ka loaʻa ʻana o ka chemotherapy ke ʻoi aku ka maikaʻi o ka lāʻau lapaʻau i manaʻo ʻia a me ka liʻiliʻi o nā hopena ʻaoʻao
• Ka nalo ʻana i nā manawa kūpono no nā lāʻau lapaʻau e pale ana i ka hormone i nā maʻi maʻi receptor hormone-positive
• Hoʻopaneʻe ʻia ka ʻike ʻana i nā maʻi maʻi maʻi hoʻoilina e pili ana i ka hoʻolālā lapaʻau
• ʻO ka hoʻonohonoho lapaʻau suboptimal e hōʻemi ana i ka pono o nā lāʻau lapaʻau ma hope
• Hoʻonui ʻia ka pilikia o ka hoʻi hou ʻana o ka maʻi ma muli o ke koho lapaʻau mua ʻole

ʻO ka lono maikaʻi, ke lilo nei ka lāʻau lapaʻau pololei i mea maʻamau no ka mālama ʻana i ka maʻi ʻaʻai umauma. I kēia manawa, hana maʻamau ka hapa nui o nā kikowaena maʻi ʻaʻai i ka hoʻāʻo genetic e hōʻoia e loaʻa iā ʻoe nā lāʻau lapaʻau kūpono loa no kāu ʻano maʻi ʻaʻai.

I ka manawa hea e ʻike ai au i ke kauka no ke kūkākūkā ʻana i ka lāʻau lapaʻau pololei?

Pono ʻoe e kūkākūkā i nā koho lāʻau lapaʻau pololei me kāu oncologist i ka wā hiki wawe ma hope o ka ʻike ʻia ʻana o kāu maʻi ʻaʻai umauma. Hiki i ka hoʻāʻo genetic mua a me ka profiling tumor ke kōkua i ke alakaʻi ʻana i kāu mau hoʻoholo lapaʻau mua a hoʻomaikaʻi i kāu mau hopena holoʻokoʻa.

Inā ʻaʻole ʻoe i hana i ka hoʻāʻo genetic piha o kāu maʻi, pono e nīnau i kāu hui lapaʻau e pili ana i kēia mau koho. ʻOiai inā ua hoʻomaka mua ʻoe i ka lapaʻau, hiki i ka hoʻāʻo ʻana i ka lāʻau lapaʻau pololei ke hāʻawi i ka ʻike waiwai no ka hoʻoponopono ʻana i kāu lāʻau lapaʻau i kēia manawa a i ʻole ka hoʻolālā ʻana i nā lāʻau lapaʻau e hiki mai ana.

E noʻonoʻo e ʻimi i ke kūkākūkā ʻana i ka lāʻau lapaʻau pololei inā ʻoe e ʻike i kekahi o kēia mau kūlana:

• ʻAʻole e hana ana kāu lapaʻau i kēia manawa e like me ka mea i manaʻo ʻia
• Ke ʻike nei ʻoe i nā hopena ʻaoʻao koʻikoʻi mai nā lāʻau lapaʻau maʻamau
• Ua hoʻi mai kāu maʻi ʻaʻai ma hope o ka lapaʻau mua
• He moʻolelo ʻohana kou o ka umauma, ovarian, a i ʻole nā maʻi ʻaʻai ʻē aʻe
• Makemake ʻoe e komo i nā hoʻokolohua lapaʻau no nā lāʻau lapaʻau i manaʻo ʻia

Nui nā kikowaena maʻi ʻaʻai i nā papahana lāʻau lapaʻau pololei me nā loea e kālele ana i ka hoʻohālikelike ʻana i nā maʻi me nā lāʻau lapaʻau i manaʻo ʻia. Hiki i kēia mau papahana ke waiwai nui inā loaʻa iā ʻoe kahi ʻano maʻi ʻaʻai umauma.

Nā nīnau i nīnau pinepine ʻia e pili ana i ka lāʻau lapaʻau pololei no ka maʻi ʻaʻai umauma

Q.1 Ua uhi ʻia ka hoʻāʻo ʻana i ka lāʻau lapaʻau pololei e ka ʻinikua?

Ua uhi ka hapa nui o nā hoʻolālā ʻinikua, me Medicare, i ka hoʻāʻo ʻana i ka lāʻau lapaʻau pololei no ka maʻi ʻaʻai umauma ke manaʻo ʻia he mea pono e nā kauka oncologists. Eia naʻe, hiki ke ʻokoʻa ka uhi ʻana ma muli o kāu hoʻolālā ʻinikua a me ke ʻano o ka hoʻāʻo ʻana i ʻōlelo ʻia.

Hiki i ke keʻena o kāu hui lapaʻau ke kōkua i ka hōʻoia ʻana i kāu uhi ʻinikua ma mua o ka hoʻomaka ʻana o ka hoʻāʻo. Nui nā hui hoʻāʻo e hāʻawi pū ana i nā papahana kōkua kālā inā pilikia ʻoe i ka uhi ʻana. Mai ʻae i nā hopohopo e pili ana i ke kumukūʻai e pale iā ʻoe mai ke kūkākūkā ʻana i nā koho lāʻau lapaʻau pololei me kāu kauka.

Q.2 Ua hana anei ka lāʻau lapaʻau pololei no nā ʻano maʻi ʻaʻai umauma a pau?

Hiki i nā ala lāʻau lapaʻau pololei ke pōmaikaʻi i nā ʻano maʻi ʻaʻai umauma a pau, ʻoiai e ʻokoʻa nā lāʻau lapaʻau i loaʻa ma muli o nā ʻano genetic o kāu maʻi ʻaʻai. Loaʻa i kekahi mau ʻano maʻi ʻaʻai umauma nā koho therapy i manaʻo ʻia ma mua o nā mea ʻē aʻe.

ʻO nā maʻi ʻaʻai umauma triple-negative, i loaʻa i ka liʻiliʻi o nā koho lapaʻau i manaʻo ʻia, ke pōmaikaʻi nei mai nā ala lāʻau lapaʻau pololei. Ke ʻike nei nā mea noiʻi i nā pahuhopu genetic hou a ke hoʻomohala nei i nā lāʻau lapaʻau e pili ana i kēia mau maʻi ʻoi aku ka paʻakikī.

Q.3 Pehea ka pinepine e hana hou ʻia ai ka hoʻāʻo ʻana i ka lāʻau lapaʻau pololei?

Hiki i kāu kauka ke ʻōlelo aku e hana hou i ka hoʻāʻo ʻana inā pau kāu maʻi ʻaʻai i ka pane ʻana i nā lāʻau lapaʻau o kēia manawa a i ʻole inā hoʻi mai ia ma hope o ka manawa hoʻomaha. Hiki i nā cell maʻi ʻaʻai ke loaʻa nā mutations hou i ka manawa, no laila hiki i ka hoʻāʻo genetic hou ke hōʻike i nā koho lapaʻau hou.

Aia ka manawa o ka hoʻāʻo hou ʻana i kāu kūlana pilikino a me ke ʻano o ka pane ʻana o kāu maʻi ʻaʻai i ka lāʻau lapaʻau. E aʻo aku kāu oncologist iā ʻoe i ka manawa e pono ai ka hoʻāʻo hou ʻana no kāu hihia.

Q.4 Hiki i ka lāʻau lapaʻau pololei ke kōkua i ka pale ʻana i ka hoʻi hou ʻana o ka maʻi ʻaʻai umauma?

Hiki i ka lāʻau lapaʻau pololei ke kōkua i ka hōʻemi ʻana i ka pilikia o ka hoʻi hou ʻana o ka maʻi ʻaʻai umauma ma ka hōʻoia ʻana e loaʻa iā ʻoe ka lāʻau lapaʻau mua loa no kāu ʻano maʻi ʻaʻai. Kōkua kekahi mau ʻike genetic i ka wānana ʻana i ka pilikia o ka hoʻi hou ʻana a alakaʻi i nā hoʻoholo e pili ana i nā lāʻau lapaʻau pale hou.

No ka laʻana, hiki i kekahi mau hoʻokolohua genetic ke kōkua i ka hoʻoholo ʻana inā e pōmaikaʻi ʻoe mai ka lāʻau lapaʻau hormone i hoʻonui ʻia a i ʻole ka chemotherapy hou e hōʻemi i ka pilikia o ka hoʻi hou ʻana. Hoʻohana kāu hui lapaʻau i kēia ʻike e hana i kahi hoʻolālā ola holoʻokoʻa i hoʻopilikino ʻia i kāu mau pono.

Q.5 He aha ka mea e hana ai inā ʻaʻohe lāʻau lapaʻau i manaʻo ʻia no nā loli o ka maʻi ʻaʻai?

ʻOiai ʻaʻole i loaʻa nā lāʻau lapaʻau i manaʻo ʻia no nā loli o kāu maʻi ʻaʻai, he mea waiwai nō ka ʻike genetic no ka hoʻolālā lapaʻau. Hiki i kāu hui lapaʻau ke hoʻohana i kēia ʻike e koho i nā ʻano chemotherapy kūpono loa a i ʻole e noʻonoʻo i nā hoʻokolohua lapaʻau e hoʻāʻo ana i nā lāʻau lapaʻau i manaʻo ʻia.

Ke ulu wikiwiki nei ke kahua o ka lāʻau lapaʻau pololei, me nā lāʻau lapaʻau i manaʻo ʻia e hoʻomohala mau ʻia. E mālama kāu oncologist iā ʻoe i ka ʻike e pili ana i nā koho lapaʻau e puka mai ana i hiki ke loaʻa no ke ʻano genetic o kāu maʻi ʻaʻai i ka wā e hiki mai ana.