Gịnị bụ Acitretin: Ojiji, Ọgwụ, Mmetụta Akụkụ na Ihe Ọzọ

Acitretin bụ ọgwụ ọnụ siri ike nke sitere na klaasị ọgwụ a na-akpọ retinoids, nke nwere njikọ chiri anya na vitamin A. Dọkịta gị nwere ike ịnye ọgwụ a ma ọ bụrụ na ị na-eche nsogbu psoriasis siri ike nke na-anaghị azaghachi nke ọma na ọgwụgwọ ndị ọzọ.

Ọgwụ a na-arụ ọrụ site n'ibelata uto ngwa ngwa nke mkpụrụ ndụ akpụkpọ ahụ nke na-akpata ntụpọ siri ike, nke na-egbuke egbuke nke psoriasis. Ọ bụ ezie na ọ nwere ike ịdị irè nke ukwuu, acitretin chọrọ nlekota anya n'ihi ike ya na mmetụta akụkụ ya nwere ike ime.

Gịnị bụ Acitretin?

Acitretin bụ retinoid synthetic nke na-eṅomi mmetụta nke vitamin A n'ime ahụ gị. Emebere ya kpọmkwem iji gwọọ ọnọdụ akpụkpọ ahụ siri ike site n'ịchịkwa otú mkpụrụ ndụ akpụkpọ ahụ gị na-eto eto ma na-awụpụ.

A na-ewere ọgwụ a dị ka ọgwụgwọ usoro, nke pụtara na ọ na-arụ ọrụ n'ime ahụ gị dum kama naanị n'elu akpụkpọ ahụ gị. N'adịghị ka ọgwụgwọ topical ị na-etinye ozugbo na mpaghara ndị metụtara, acitretin na-agafe n'ọbara gị iji ruo mkpụrụ ndụ akpụkpọ ahụ ebe niile.

Ọgwụ a bara uru karịsịa maka ndị nwere psoriasis n'ihi na ọ na-edozi usoro cellular dị n'okpuru nke na-akpata ọnọdụ na-adịghị ala ala a. Ọ na-enyere aka ime ka ụzọ akpụkpọ ahụ gị na-emepụta ma dochie mkpụrụ ndụ.

Gịnị ka a na-eji Acitretin eme ihe?

A na-edekarị Acitretin maka psoriasis siri ike, ọkachasị mgbe ọgwụgwọ ndị ọzọ enyeghị enyemaka zuru oke. Dọkịta gị ga-atụlekarị ọgwụ a mgbe ọgwụgwọ topical na ọgwụgwọ ọkụ anaghị arụ ọrụ nke ọma.

Ọgwụ a na-arụ ọrụ nke ọma maka ụdị psoriasis ụfọdụ nke nwere ike ịbụ ihe ịma aka karịsịa iji gwọọ ya. Nke a bụ isi ọnọdụ ebe acitretin na-egosi uru kachasị:

• Ọrịa psoriasis siri ike na-ekpuchi nnukwu akụkụ ahụ gị
• Pustular psoriasis, nke na-akpata ntụpọ jupụtara na pus n'ahụ gị
• Erythrodermic psoriasis, ụdị dị ụkọ ma dị njọ nke na-emetụta ọtụtụ akụkụ ahụ gị
• Psoriasis na-emetụta nkwụ na mkpịsị ụkwụ gị, nke nwere ike isi ike

N'ọnọdụ ụfọdụ, ndị dọkịta nwekwara ike ịnye acitretin maka ọnọdụ akpụkpọ ahụ siri ike ndị ọzọ dị ka ụdị ichthyosis ma ọ bụ ọrịa keratosis. Otú ọ dị, psoriasis ka bụ ihe a na-ejikarị eme ihe ma mụọ ya nke ọma.

Olee otú Acitretin si arụ ọrụ?

Acitretin na-arụ ọrụ site n'ịgbanwe na ndị na-anata ihe dị na mkpụrụ ndụ akpụkpọ ahụ gị ma na-achịkwa ngosipụta mkpụrụ ndụ ihe nketa. Usoro a na-enyere aka ime ka ngbanwe mkpụrụ ndụ ihe nketa na-eme ngwa ngwa nke na-egosi psoriasis.

N'ime akpụkpọ ahụ dị mma, mkpụrụ ndụ na-ewe ihe dịka ụbọchị 28 iji si n'ime ime gaa n'elu ebe ha na-agbapụ n'ụzọ nkịtị. Site na psoriasis, usoro a na-agba ọsọ ngwa ngwa ruo ụbọchị 3-4, na-emepụta ntụpọ siri ike, nke nwere ntụpọ ị na-ahụ.

Acitretin na-agwa mkpụrụ ndụ akpụkpọ ahụ gị ka ha jiri nwayọọ mee ihe ma na-akpa àgwà nke ọma. Ọ na-ebelata mbufụt ma na-enyere aka igbochi mkpokọba mkpụrụ ndụ akpụkpọ ahụ na-agafe ókè nke na-emepụta ntụpọ psoriatic.

A na-ewere ọgwụ a dị ka ihe dị ike na ụwa nke ọgwụgwọ psoriasis. Ọ bụ ezie na ọ bụghị nhọrọ kachasị ike dị, ọ dị ike karịa ọgwụgwọ topical ma nwee ike ịmepụta nnukwu mmelite n'ọnọdụ siri ike.

Kedu ka m ga-esi ewere Acitretin?

Na-ewere acitretin mgbe niile dị ka dọkịta gị nyere iwu, na-emekarị otu ugboro n'ụbọchị na nri gị bụ isi. Iwere ya na nri, karịsịa ihe nwere ụfọdụ abụba, na-enyere ahụ gị aka ịmịnye ọgwụ ahụ nke ọma.

Ị ga-achọ iloda capsules ahụ dum na iko mmiri zuru ezu. Ekwela ka ị gbarie, taa, ma ọ bụ mepee capsules ahụ, n'ihi na nke a nwere ike imetụta otú ọgwụ ahụ si arụ ọrụ ma nwee ike ịkpata mgbakasị n'ọnụ ma ọ bụ akpịrị gị.

Nke a bụ ụfọdụ ntuziaka dị mkpa ị ga-eso mgbe ị na-ewere acitretin:

• Were ya ya ya ya n'otu oge kwa ụbọchị iji mee ka ọkwa dị n'ime ahụ gị kwụsie ike
• Were ya na nnukwu nri gị nke ụbọchị maka mma mma
• Zere iwere ya na mmiri ara ehi ma ọ bụ ngwaahịa mmiri ara ehi, n'ihi na ndị a nwere ike ibelata mma
• Ekwela iwere mgbakwunye vitamin A mgbe ị na-aṅụ ọgwụ a

Dọkịta gị ga-amalite gị na obere dose ma jiri nwayọọ nwayọọ gbanwee ya dabere n'otú ị na-esi emeghachi omume na mmetụta ọ bụla ị na-enwe. Ụzọ a na-akpachara anya na-enyere aka belata nsogbu nwere ike ime ka ị na-eme ka uru dịkwuo elu.

Ogologo Oge Ka M Kwesịrị Iwere Acitretin?

Ogologo oge ọgwụgwọ acitretin dịgasị iche iche site n'otu onye gaa n'otu onye, ​​ma ọtụtụ mmadụ kwesịrị iwere ya ruo ọtụtụ ọnwa iji hụ uru zuru oke. Dọkịta gị ga-atụ aro ka ị nọgide na ọgwụ ahụ ma ọ dịkarịa ala ọnwa 3-4 iji nyochaa ịdị irè ya nke ọma.

Ọtụtụ mmadụ na-aga n'ihu na-aṅụ acitretin ruo ọnwa 6-12 ma ọ bụ karịa, dabere na nzaghachi ha na ndidi ha. Ụfọdụ ndị nwere nnukwu psoriasis nwere ike ịchọ ọgwụgwọ ogologo oge iji mee ka akpụkpọ ahụ dị ọcha.

Dọkịta gị ga-enyocha ọganihu gị mgbe niile ma nwee ike ịgbanwe atụmatụ ọgwụgwọ gị dabere na ọtụtụ ihe. Ndị a gụnyere otú akpụkpọ ahụ gị si emeghachi omume nke ọma, mmetụta ọ bụla ị na-enwe, na ọnọdụ ahụike gị niile.

Ọ dị ezigbo mkpa ka ị kwụsị iwere acitretin na mberede na-enweghị mkparịta ụka ya na dọkịta gị mbụ. Ihe mgbaàmà psoriasis gị nwere ike ịlaghachi, na n'ọnọdụ ụfọdụ, ha nwere ike ịlaghachi njọ karịa tupu a kwụsị ọgwụ ahụ na mberede.

Kedu Ihe Bụ Mmetụta Akụkụ nke Acitretin?

Dị ka ọgwụ niile dị ike, acitretin nwere ike ịkpata mmetụta, n'agbanyeghị na ọ bụghị onye ọ bụla na-enwe ha. Mmetụta ndị a na-ahụkarị metụtara mmetụta vitamin A nke ọgwụ ahụ n'ahụ gị.

Ịghọta ihe a ga-atụ anya ya nwere ike inye gị aka inwekwu nkwadebe ma mara mgbe ị ga-akpọtụrụ dọkịta gị. Nke a bụ mmetụta ndị a na-akọkarị:

• Akpụkpọ ahụ na egbugbere ọnụ akpọnwụ, nke na-emetụta ọtụtụ ndị na-aṅụ ọgwụ a
• Ntutu isi na-agbaji ma ọ bụ ntutu isi na-efunahụ nwa oge
• Anyanwụ akpọnwụ na mgbanwe anya nwere ike ime
• Akpụkpọ ahụ na-apụ na nkwụ na mkpịsị ụkwụ gị
• Mmụba nke mmetụta na ìhè anyanwụ
• Imipụta imi n'ihi akụkụ imi akpọnwụ
• Mgbu nkwonkwo ma ọ bụ akwara
• Isi ọwụwa

Ọ bụ ezie na mmetụta ndị a na-ahụkarị nwere ike ịbụ ihe na-adịghị mma, ha na-adịkarị mfe ijikwa ya site na nlekọta kwesịrị ekwesị ma na-abawanye mgbe ahụ gị na-emegharị na ọgwụ ahụ.

Mmetụta ndị dị njọ karị adịghị ahụkarị mana ha chọrọ nlekọta ahụike ozugbo. Ndị a nwere ike ịgụnye nnukwu mgbanwe ọnọdụ, ihe ịrịba ama nke nsogbu imeju dị ka ịcha akpụkpọ ahụ gị ma ọ bụ anya gị, ma ọ bụ isi ọwụwa na-adịgide adịgide.

Ụfọdụ ndị nwere ike ịnweta mmetụta dị ụkọ ma dị mkpa nke chọrọ nyocha ahụike ngwa ngwa. Ndị a gụnyere nnukwu ịda mbà n'obi, echiche nke imerụ onwe onye, ​​ma ọ bụ ihe ịrịba ama nke mmụba nrụgide n'ime okpokoro isi gị dị ka isi ọwụwa na-adịgide adịgide na mgbanwe anya.

Ònye Kwesịrị Ịghara Ịṅụ Acitretin?

Acitretin adabaghị maka onye ọ bụla, e nwere ọtụtụ ọnọdụ dị mkpa ebe a ga-ezere ọgwụ a kpamkpam. Dọkịta gị ga-enyocha akụkọ ahụike gị nke ọma tupu ịnye ya.

Ihe mgbochi kachasị mkpa gụnyere ime ime na ohere nke ime ime. Acitretin nwere ike ịkpata ntụpọ ọmụmụ dị njọ ma a gaghị ewere ya site na ụmụ nwanyị dị ime ma ọ bụ ndị nwere ike ime ime.

Nke a bụ isi otu ndị mmadụ na-ekwesịghị ịṅụ acitretin:

• Ụmụ nwanyị dị ime ma ọ bụ na-eme atụmatụ ime ime
• Ụmụ nwanyị nwere ike ime ime ma ha enweghị ike itinye aka na mgbochi ime ime a pụrụ ịdabere na ya
• Ndị nwere nnukwu ọrịa imeju ma ọ bụ nsogbu ọrụ imeju
• Ndị nwere nnukwu cholesterol ma ọ bụ ọkwa triglyceride
• Ndị nwere nnukwu ọrịa akụrụ
• Ndị na-aṅụ ọgwụ ụfọdụ na-emekọrịta ihe dị ize ndụ na acitretin

Dọkịta gị ga-akpachara anya ma ọ bụrụ na ị nwere ọrịa shuga, ọrịa obi, ma ọ bụ akụkọ ihe mere eme nke ịda mbà n'obi. Ọnọdụ ndị a anaghị egbochi gị iwere acitretin, mana ha chọrọ nlekota anya.

Ọ bụrụ na ị na-enye nwa ara, ị ga-achọ ikwurịta ihe ize ndụ na uru ya nke ọma na dọkịta gị, n'ihi na acitretin nwere ike ịbanye n'ime mmiri ara ara.

Aha Ụdị Acitretin

Acitretin dị n'okpuru ọtụtụ aha ụdị, ebe Soriatane bụ nke a na-ahụkarị na United States. Ụdị aha ụdị a nwere otu ihe na-arụ ọrụ dị ka acitretin generic.

Aha ụdị ndị ọzọ ị nwere ike izute gụnyere Neotigason na ụfọdụ mba, n'agbanyeghị na nnweta dị iche iche site na mpaghara. Ụlọ ahịa ọgwụ gị nwere ike inye ma aha ụdị ma ọ bụ ụdị generic dabere na mkpuchi mkpuchi na nnweta gị.

Ma ị na-enweta aha ụdị ma ọ bụ acitretin generic, ọgwụ ahụ na-arụ ọrụ otu ụzọ ahụ. Ụdị generic na-enweta nnwale siri ike iji hụ na ha hà nhata na ngwaahịa aha ụdị n'ihe gbasara ịdị irè na nchekwa.

Ụzọ Ọzọ Maka Acitretin

Ọ bụrụ na acitretin adabaghị gị ma ọ bụ na-enyeghị nsonaazụ zuru oke, ọtụtụ ọgwụgwọ ndị ọzọ dị maka nnukwu psoriasis. Dọkịta gị nwere ike inyere gị aka ịchọpụta nhọrọ ndị a dabere na ọnọdụ gị.

Ọgwụgwọ sistemụ ndị ọzọ nwere ike ịtụle gụnyere methotrexate, cyclosporine, ma ọ bụ ọgwụ biologic ọhụrụ. Onye ọ bụla nwere uru ya na mmetụta ndị nwere ike ime iji tụlee.

Nke a bụ ụfọdụ ụzọ ọzọ dọkịta gị nwere ike ikwurịta:

• Methotrexate, nke na-egbochi usoro ahụ ji alụso ọrịa ọgụ gị iji belata mbufụt
• Cyclosporine maka njikwa obere oge nke nnukwu ọkụ
• Ọgwụ biologic dị ka adalimumab ma ọ bụ ustekinumab
• Apremilast, ọgwụ ọnụ nke na-arụ ọrụ dị iche na acitretin
• Ọgwụgwọ phototherapy na-eji ìhè UV

Ụzọ kacha mma ga-adabere n'ọtụtụ ihe, gụnyere akụkọ ahụike gị, oke nsogbu psoriasis gị, na mmasị nke gị. Dọkịta gị ga-arụkọ ọrụ na gị iji chọta nhọrọ kacha mma.

Nke a Acitretin ka Methotrexate mma?

Ma acitretin na methotrexate bụ ọgwụgwọ dị irè maka nnukwu psoriasis, mana ha na-arụ ọrụ n'ụzọ dị iche iche ma nwee ike dị iche iche. Ọ dịghị nke ọ bụla bụ nke "ka mma" karịa nke ọzọ - nhọrọ kacha mma dabere na ọnọdụ gị.

Acitretin na-arụ ọrụ site n'ịhazi uto sel akpụkpọ ahụ ma anaghị egbochi usoro ahụike gị dị ka methotrexate na-eme. Nke a pụtara na ị nọghị n'ihe ize ndụ nke ọrịa, nke nwere ike ịbụ uru maka ụfọdụ ndị.

Methotrexate, n'aka nke ọzọ, na-arụ ọrụ site n'ibelata nzaghachi mkpali nke na-akpata psoriasis. Ọ na-arụkarị ọrụ ngwa ngwa karịa acitretin ma nwee ike ịka mma maka psoriatic arthritis ma ọ bụrụ na ị nwere mgbaàmà nkwonkwo.

Dọkịta gị ga-atụle ọtụtụ ihe mgbe ị na-ahọrọ n'etiti ọgwụ ndị a, gụnyere ahụike gị n'ozuzu ya, ọnọdụ ahụike ndị ọzọ, na otú psoriasis gị si emetụta ndụ gị kwa ụbọchị. Ụfọdụ ndị na-eji ọgwụ abụọ ahụ ọnụ n'okpuru nlekọta ahụike nke ọma.

Ajụjụ A Na-ajụkarị Banyere Acitretin

Acitretin ọ dị mma maka ndị nwere ọrịa shuga?

Ndị nwere ọrịa shuga nwere ike iji Acitretin, mana ọ chọrọ nlekota anya. Ọgwụ ahụ nwere ike imetụta ọkwa shuga dị n'ọbara gị ma nwee ike imekọrịta ihe na ụfọdụ ọgwụ ọrịa shuga.

Dọkịta gị ga-achọ ileba anya shuga dị n'ọbara gị anya mgbe ị malitere acitretin. Ha nwekwara ike ịgbanwe ọgwụ ọrịa shuga gị ma ọ bụ tụọ aro mgbanwe na nri gị na usoro mmega ahụ.

Ọ bụrụ na ị nwere ọrịa shuga, gwa dọkịta gị gbasara ọgwụ ọrịa shuga gị niile na otú e si achịkwa shuga dị n'ọbara gị. Ozi a na-enyere ha aka ikpebi ma acitretin kwesịrị ekwesị maka gị.

Gịnị Ka M Ga-eme ma ọ bụrụ na m were Acitretin gabigara ókè na mberede?

Ọ bụrụ na i were acitretin karịa ka e nyere gị iwu na mberede, kpọtụrụ dọkịta gị ma ọ bụ ebe a na-achịkwa nsí ozugbo. Iwere ya gabigara ókè nwere ike ibute nsí vitamin A, nke nwere ike ibute nnukwu mgbaàmà.

Ihe ịrịba ama nke acitretin overdose nwere ike ịgụnye isi ọwụwa siri ike, ọgbụgbọ, agbọ, isi ọwụwa, ma ọ bụ ọhụụ na-adịghị mma. Echela ka mgbaàmà pụta - chọọ ndụmọdụ ahụike ozugbo ma ọ bụrụ na i wereela dose ndị ọzọ.

Iji gbochie overdose na mberede, debe ọgwụ gị na akpa mbụ ya wee were ya n'otu oge kwa ụbọchị. Etinyela dose okpukpu abụọ ma ọ bụrụ na ị tụfuru otu.

Gịnị Ka M Ga-eme ma ọ bụrụ na m tụfuru dose Acitretin?

Ọ bụrụ na ị tụfuru dose acitretin, were ya ozugbo i chetara, ọkacha mma na nri. Agbanyeghị, ọ bụrụ na ọ fọrọ nke nta ka ọ bụrụ oge maka dose gị na-esote, gbaghara dose ahụ tụfuru wee gaa n'ihu na usoro ihe omume gị mgbe niile.

Etinyela dose abụọ n'otu oge iji mezie dose tụfuru. Nke a nwere ike ịbawanye ohere nke mmetụta dị n'akụkụ na-enweghị uru ọ bụla.

Ọ bụrụ na ị na-echefukarị dose, gbalịa ịtọ mkpu kwa ụbọchị ma ọ bụ were ọgwụ gị n'otu oge dị ka ihe ọzọ kwa ụbọchị, dị ka nri abalị. Oge na-aga n'ihu na-enyere aka idobe ọkwa ọgwụ na-adịgide adịgide n'ime ahụ gị.

Kedu mgbe m nwere ike ịkwụsị iwere Acitretin?

Naanị ị ga-akwụsị iwere acitretin n'okpuru nduzi dọkịta gị. Ọtụtụ ndị mmadụ kwesịrị ịga n'ihu na ọgwụ ahụ ruo ọtụtụ ọnwa iji mee ka akpụkpọ ahụ dị ọcha, na ịkwụsị n'oge nwere ike ime ka psoriasis gị laghachi.

Dọkịta gị ga-enyocha ọganihu gị mgbe niile ma nwee ike ibelata dose gị nwayọọ nwayọọ tupu ịkwụsị kpamkpam. Ụzọ a na-enyere aka belata ihe ize ndụ nke psoriasis gị na-apụta mgbe a kwụsịrị ya.

Ụfọdụ ndị mmadụ nwere ike ịnọ na acitretin ogologo oge iji mee ka psoriasis ha nọgide na-achịkwa. Dọkịta gị ga-atụle uru megide ihe ize ndụ ogologo oge ma kwurịta atụmatụ mmezi kacha mma maka ọnọdụ gị.

\u0160\u1ee5 m nwere ike \u1ee4\u1ee5 \u1ee4\u1ee5\u1ecb mmanya mgbe m na-a\u1ecba Acitretin?

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