Upadacitinib (ụzọ ọnụ)
Ụdị dịnụ
Rinvoq, Rinvoq LQ
Gbasara ọgwụ a
A na-eji Upadacitinib agwọ ọrịa mgbu mgbu rheumatoid nke dị elu ruo oke, ọrịa mgbu mgbu psoriatic na-arụ ọrụ, ankylosing spondylitis, non-radiographic axial spondyloarthritis (ụdị ọrịa mgbu mgbu na azụ) nke nwere ihe ngosi nke mgbawa, ọrịa ulcerative colitis nke dị elu ruo oke, ọrịa Crohn nke dị elu ruo oke, na polyarticular juvenile idiopathic arthritis (PJIA) na ndị ọrịa ejiriwo ọgwụ ọzọ (dịka, methotrexate) nke na-arụghị ọrụ nke ọma. A na-eji ya agwọ ọrịa atopic dermatitis (eczema) nke dị elu ruo oke na ndị ọrịa ejiriwo ọgwụ ọzọ nke na-arụghị ọrụ nke ọma, ma ọ bụ ndị ọrịa ahụike ha adịghị mma site na ọgwụgwọ ndị ọzọ, ma ọ bụ ndị ọrịa na-enweghị ike ịnagide ọgwụgwọ ndị ahụ. Upadacitinib bụ onye na-egbochi Janus kinase (JAK) nke na-arụ ọrụ na usoro ọgwụ mgbochi ahụ. A na-enweta ọgwụ a naanị site na ntụziaka dọkịta gị. A na-enweta ngwaahịa a na ụdị ọgwụgwọ ndị a na-esonụ:
Tupu iji ọgwụ a
Mgbe ị na-ekpebi iji ọgwụ ọ bụla, a ghaghị ịtụle ihe egwu nke ịṅụ ọgwụ ahụ megide uru ọ ga-eme. Nke a bụ mkpebi gị na dọkịta gị ga-eme. Maka ọgwụ a, a ghaghị ịtụle ihe ndị a: Gwa dọkịta gị ma ọ bụrụ na ị na-enwe mmeghachi omume ọ bụla na-adịghị mma ma ọ bụ mmeghachi omume dị iche iche na ọgwụ a ma ọ bụ ọgwụ ndị ọzọ. Gwa onye ọrụ ahụike gịkwa ma ọ bụrụ na ị nwere ụdị mmeghachi omume ndị ọzọ, dị ka nri, ihe na-acha, ihe na-echekwa, ma ọ bụ anụmanụ. Maka ngwaahịa ndị anaghị achọ ntụziaka, gụọ akara ma ọ bụ ihe ndị dị na ngwugwu ahụ nke ọma. A na-emeghị nyocha kwesịrị ekwesị banyere mmekọrịta nke afọ na mmetụta nke upadacitinib iji gwọọ ọrịa rheumatoid arthritis, ankylosing spondylitis, non-radiographic axial spondyloarthritis, ulcerative colitis, na Crohn's disease na ụmụaka, iji gwọọ psoriatic arthritis na PJIA na ụmụaka dị afọ erughị afọ 2, na iji gwọọ atopic dermatitis na ụmụaka dị afọ erughị afọ 12. A na-emeghị ka nchekwa na arụmọrụ dị mma. Nyocha kwesịrị ekwesị e mere ruo ugbu a egosilaghị nsogbu ndị metụtara ndị agadi nke ga-ebelata uru nke upadacitinib na ndị agadi. Otú ọ dị, ndị agadi nwere ike inwe ọrịa na-egbu egbu na kansa, nke nwere ike ịchọ nlezianya na ndị ọrịa na-aṅụ upadacitinib. Enweghị nyocha zuru oke na ụmụ nwanyị maka ịchọpụta ihe egwu nke ụmụ ọhụrụ mgbe ejiri ọgwụ a mgbe ị na-enye ara. Tụlee uru ndị dị na ya megide ihe egwu ndị dị na ya tupu ịṅụ ọgwụ a mgbe ị na-enye ara. Ọ bụ ezie na a gaghị eji ụfọdụ ọgwụ ọnụ ọnụ, n'ọnọdụ ndị ọzọ, a pụrụ iji ọgwụ abụọ dị iche iche ọnụ ọbụna ma ọ bụrụ na mmekọrịta nwere ike ime. N'ọnọdụ ndị a, dọkịta gị nwere ike ịchọ ịgbanwe ọgwụ ahụ, ma ọ bụ nlekọta ndị ọzọ nwere ike ịdị mkpa. Mgbe ị na-aṅụ ọgwụ a, ọ dị mkpa karịsịa na onye ọrụ ahụike gị mara ma ọ bụrụ na ị na-aṅụ ọgwụ ọ bụla dị na ndepụta dị n'okpuru. A họọrọ mmekọrịta ndị a dabere na mkpa ha nwere ike inwe ma ọ bụghị ihe niile. Iji ọgwụ a na ọgwụ ọ bụla dị n'okpuru ebe a anaghị atụ aro ya, mana ọ nwere ike ịchọrọ n'ọnọdụ ụfọdụ. Ọ bụrụ na e dere ọgwụ abụọ ahụ ọnụ, dọkịta gị nwere ike ịgbanwe ọgwụ ahụ ma ọ bụ otú ị ga-eji otu ma ọ bụ abụọ n'ime ọgwụ ndị ahụ. A gaghị eji ụfọdụ ọgwụ mgbe ị na-eri nri ma ọ bụ mgbe ị na-eri ụdị nri ụfọdụ n'ihi na mmekọrịta nwere ike ime. Iji mmanya ma ọ bụ ọgwụ na ụfọdụ ọgwụ nwekwara ike ime ka mmekọrịta ime. A họọrọ mmekọrịta ndị a dabere na mkpa ha nwere ike inwe ma ọ bụghị ihe niile. Iji ọgwụ a na ọ bụla n'ime ndị a anaghị atụ aro ya, mana ọ nwere ike ịbụ ihe a na-apụghị izere n'ọnọdụ ụfọdụ. Ọ bụrụ na ejiri ya ọnụ, dọkịta gị nwere ike ịgbanwe ọgwụ ahụ ma ọ bụ otú ị ga-eji ọgwụ a, ma ọ bụ nye gị ntụziaka pụrụ iche banyere iji nri, mmanya, ma ọ bụ ọgwụ. Ịdị adị nke nsogbu ahụike ndị ọzọ nwere ike imetụta ojiji nke ọgwụ a. Jide n'aka na ị gwa dọkịta gị ma ọ bụrụ na ị nwere nsogbu ahụike ndị ọzọ, karịsịa:
Otu esi eji ọgwụ a
Were ọgwụ a kpọmkwem dịka dọkịta gị si nye iwu. Etinyeghị ya karịa ma ọ bụ obere, etinyeghị ya mgbe niile, wee ghara itinye ya ogologo oge karịa dọkịta gị nyere iwu. Ọgwụ a bịara na Nduzi Ọgwụ na ntụziaka ndị ọrịa. Gụọ ma soro ntụziaka ahụ n'ụzọ zuru ezu. Jụọ dọkịta gị ma ọ bụrụ na ị nwere ajụjụ ọ bụla. Ị nwere ike were ọgwụ a na nri ma ọ bụ na-enweghị nri. Mee ka 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