Coagulation factor ix recombinant (intravenous route)

Benefix, Ixinity, Rixubis

Coagulation factor IX, recombinant injection is used to treat, control, prevent, and decrease the frequency of bleeding episodes, and prevent bleeding during surgery in patients with hemophilia B (congenital Factor IX deficiency or Christmas disease). Factor IX is a protein that is produced naturally in the body. This medicine is a man-made protein produced to replicate the naturally occurring factor IX in the body. It is used to stop bleeding by helping the blood to clot in patients with hemophilia B. This medicine is to be given only by or under the supervision of your doctor and is available only with your doctor's prescription. This product is available in the following dosage forms:

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects ofIxinity®in children younger than 12 years of age. Safety and efficacy have not been established. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness ofBeneFIX®to prevent or decrease the frequency of bleeding episodes in children 16 years of age and older, or to treat and control bleeding episodes or prevent bleeding during surgery in children younger than 12 years of age. However, because ofBeneFIX®'stoxicity, it should be used with caution and an adjustment in the dose is needed. Children should be carefully monitored during treatment. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness ofRixubis™in children. Although appropriate studies on the relationship of age to the effects of coagulation factor IX, recombinant injection have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: