He Pai ake a Wellbutrin, a Lexapro rānei? Ngā Whakamahinga, Ngā Paanga Kino, me te Paihere

He aha te pai ake mō te manawawhiti, mō te pouri rānei: Wellbutrin, mō Lexapro rānei? Ko Lexapro te nuinga e pai ake ana mō te manawawhiti; e rua e pai ana ki te rongoā pouri. Ka whakanui a Wellbutrin i te kaha engari ka taea te kino i te manawawhiti ki ētahi tāngata.

He aha te rerekētanga i waenganui i a Wellbutrin me Lexapro?

I ētahi wā, ka mārama ake ngā rerekētanga matua i te taha o tētahi ki tētahi. Anei tētahi ripanga whakarite tere hei timatatanga mā tātou, e titiro ana ki te bupropion me te escitalopram (ngā ingoa whānui mō Wellbutrin me Lexapro).

Āhuatanga	Wellbutrin (Bupropion)	Lexapro (Escitalopram)
Momo Rongoā	NDRI (Norepinephrine-Dopamine Reuptake Inhibitor)	SSRI (Selective Serotonin Reuptake Inhibitor)
Me Pēhea te Mahi	Ka whakanui i ngā taumata o te norepinephrine me te dopamine i roto i te roro.	Ka whakanui i ngā taumata o te serotonin i roto i te roro.
Ngā Whakamahinga kua Whakaaetia e te FDA	Major Depressive Disorder (MDD), Seasonal Affective Disorder (SAD), Te Kati Paoa.	Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD).
Ngā Paanga Kino Noa	Te ohoroa, te waha maroke, te mamae o te upoko, te ngākau whakatā, te ruaki, te whānaha.	Te ruaki, te moe, te werawera, te ngoikore o te ira tangata, te waha maroke.
Te Tūponotanga o Ngā Paanga Kino ki te Ira Tangata	He iti rawa. I ētahi wā ka whakamahia hei whakakore i ngā paanga kino ki te ira tangata mai i ētahi atu rongoā pouri.	Teitei ki te wawaenga. Ka taea te ngoikore o te hiahia, te roa o te orgasm, me te raru o te erektion.
Pānga ki te Taumaha	I te nuinga o te wā ka hono ki te whakaheke taumaha, ki te kore rānei e pā ki te taumaha.	Ka taea te hono ki te taumaha, otirā ki te whakamahi roa.

Me Pēhea te Mahi? Te Rerekētanga Matua (NDRI ki te SSRI)

Ko te rerekētanga nui i waenganui i ēnei rongoā e rua kei roto i te pēnei o te taunekeneke ki ngā karere matū o tō roro, ki ngā neurotransmitters rānei. Ko te mārama ki tēnei te matua ki te mārama ki te take i rerekē ai ō rātou pānga me ō rātou paanga kino. Koinei te ngākau o te NDRI ki te SSRI te matapopore.

Lexapro: Te Tohunga Serotonin (SSRI)

Ko Lexapro (escitalopram) kei roto i te momo rongoā pouri tino noa: Selective Serotonin Reuptake Inhibitors (SSRIs). whakaarohia te serotonin hei kaitautoko o tō roro mō te "pai te ngākau" me te "whakamatatete". He nui te tūranga kei roto i te ngākau, te manawawhiti, te moe, me te ahua whānui o te oranga.

Ka mahi te SSRI mā te aukati i te reuptake (te tango anō rānei) o te serotonin ki roto i ngā pūtau nerve. Ma tenei ka nui ake te serotonin e wātea ana i roto i te synaptic gap—te wāhi i waenganui i ngā neuron—ka āhei ai ki te tuku pai ake i ngā tohu e pā ana ki te ngākau pai me te marino. He huarahi tātari kei te aro noa ki te whakanui i te serotonin. E ai ki ngā rangahau i whakaputaina i roto i te Molecular Brain, he tino pai tēnei tikanga mō ngā tohu pouri me te manawawhiti pūtake.

Wellbutrin: Te Rōpū Whakanui-Kaha (NDRI)

Kei roto a Wellbutrin (bupropion) i tētahi atu wāhi. E kiia ana he "rongoā pouri atypical" nā te mea kāore e pā ki te serotonin. Engari, he Norepinephrine-Dopamine Reuptake Inhibitor (NDRI) tērā.

Ka mahi tērā pera i te SSRI engari ki ngā neurotransmitters e rua rerekē: * Norepinephrine: Ka honoa tēnei matū ki te mārama, te kaha, me te aro. * Dopamine: E kīia ana ko te matū "utu", he mea nui te dopamine mō te hihiri, te koa, me te arotahi.

Mā te whakanui i te wātea o tēnei tokorua, he nui ake te pānga whakahihiko, whakanui-kaha rānei a Wellbutrin. Ko tēnei tikanga te whakamārama ki te take i tino āwhina ai ki ngā tāngata kua whakaatu te pouri i a rātou hei ngenge, hei māngere, me te kore e āhei te rongo i te koa.

Ngā Āhuatanga ka Rongoa: Kei tua atu i te Depress Major

Ahakoa kua whakaaetia e rua mō te Major Depressive Disorder, ko ō rātou tikanga motuhake ka āhei ai ki te momo āhuatanga rerekē, kua whakaaetia (kua whakaaetia e te FDA) me te kāore i whakaaetia.

Mō aha te Wellbutrin e whakamahia ana?

He maha ngā momo o Wellbutrin—immediate-release (IR), sustained-release (SR), me te extended-release (XL)—e pā ana ki te pehea te horopeta me te aha e whakamahia ai.

• Ngā Whakamahinga kua Whakaaetia e te FDA:
  • Major Depressive Disorder (MDD)
  • Seasonal Affective Disorder (SAD), tētahi momo pouri e pā ana ki ngā huringa wā.
  • Te Kati Paoa (i raro i te ingoa waitohu Zyban).
• Ngā Whakamahinga Kāore i Whakaaetia (Off-Label) Noa:
  • Attention-Deficit/Hyperactivity Disorder (ADHD), nā te pānga ki te dopamine me te norepinephrine, he mea nui ki te aro me te mahi whakahaere pūtake.
  • Bipolar Depression (i te nuinga o te wā me te kaiwhakariterite manawa).

Ahakoa tērā ētahi e pātai ana mō te Wellbutrin mō te manawawhiti, kāore i te nuinga te maimoatanga tuatahi. Ki ētahi tāngata, ka taea e tōna pānga whakahihiko te kino ake i te manawawhiti, te whakaputa rānei i te ngākau whakatā.

Mō aha a Lexapro e whakamahia ana?

Ko Lexapro te kōwhiringa matua mō ngā āhuatanga kei reira te manawawhiti me te pouri e hono tahi ana.

• Ngā Whakamahinga kua Whakaaetia e te FDA:
  • Major Depressive Disorder (MDD)
  • Generalized Anxiety Disorder (GAD)
• Ngā Whakamahinga Kāore i Whakaaetia (Off-Label) Noa:
  • Obsessive-Compulsive Disorder (OCD)
  • Panic Disorder
  • Post-Traumatic Stress Disorder (PTSD)
  • Premenstrual Dysphoric Disorder (PMDD)

Paihere: He rite tō rāua pai mō te pouri?

I te wāhi ki te rongoā i ngā tohu matua o te pouri nui, ko te whakautu poto ko te ae. Kua kitea e ngā rangahau nui e rite ana te pai o Wellbutrin me Lexapro. I kitea e tētahi arotake nui o te paihere rongoā pouri, e mōhiotia ana ko te STAR\*D trial, e rite ana te pai o ngā momo rongoā pouri rerekē, engari ka rerekē te urupare o ngā tāngata pūtake.

Na, ki te pai kē, me pēhea te kōwhiri? Ka hoki te whakatau ki te wāhi ehara i te mea mehemea ka pai, engari me pēhea te mahi me ngā paanga kino e pai ana te tangata ki te rongo. Ko te rongoā "pai ake" ko tērā e tino rite ana ki tō tauira tohu motuhake me tō oranga.

Ngā Paanga Kino: Te Kōwhiringa Whakamutunga mō te Toko Maha

Ko tēnei pea te wāhanga tino nui o te Wellbutrin ki te Lexapro te matapopore mō te tini o te tāngata. Ko ngā āhua o ngā paanga kino e tino rerekē ai ēnei rongoā e rua.

Ngā Paanga Kino Tāpiri

Tuatahi, tirohia te wāhi kotahi. Ka taea e ngā rongoā e rua te whakaputa: * Te waha maroke * Te ruaki (ina koa ka tīmata) * Te ohoroa * Te mamae o te upoko * Te whānaha

He ngāwari ēnei paanga kino, ā, ka iti haere i te wā ka urutau tō tinana ki te rongoā i roto i ētahi wiki.

Te Rerekētanga Matua #1: Ngā Paanga Kino ki te Ira Tangata

Koinei tētahi wāhanga nui o te rerekētanga. * Ngā Paanga Kino o Lexapro: Pērā ki ētahi atu SSRIs, he mōhiohio nui a Lexapro mō te tūponotanga o te raru o te mahi ira tangata. Ka taea tēnei te whakauru i te ngoikore o te libido (iti te hiahia), te roa o te ejaculation i ngā tāne, me te uaua ki te tae rānei ki te orgasm i ngā tāne me ngā wahine. Ki ētahi, he nui rawa tēnei paanga kino ki te whakamutu i te maimoatanga. * Ngā Paanga Kino ki te Ira Tangata o Wellbutrin: E mōhiotia ana a Wellbutrin mō te tino iti o te paanga kino ki te ira tangata. Nā te mea kāore e pā ki te serotonin, ka karo i ngā raruraru noa o ngā SSRIs. Kua tae ki te wāhi ka tohua tērā i te taha o te SSRI hei whakakore i ngā paanga kino ki te ira tangata.

Te Rerekētanga Matua #2: Ngā Huringa Taumaha

Ko te āwangawanga mō te taumaha ka ārai nui ki te timata, ki te haere tonu rānei i te maimoatanga pouri. * Taumaha o Lexapro: Ahakoa kāore ērā katoa e kite, ko te taumaha o Lexapro he mea ka taea, ina koa ki te whakamahia mō te ono marama, neke atu rānei. Kāore i te tino mōhiotia te take, engari ka pā pea ki ngā pānga o te serotonin ki te hiahia kai me te metabolism. * Te whakaheke taumaha o Wellbutrin: Engari, ko te whakaheke taumaha o Wellbutrin te paanga kino tino noa. Ka taea e tōna pānga whakahihiko te whakanui i te metabolism me te whakaiti i te hiahia kai, ka waiho hei kōwhiringa pai mō ngā tāngata e āwangawanga ana mō te taumaha.

Ngā Paanga Kino Nui me te Whakatūpato Pouaka

He mea nui kia mōhio ki ngā pānga kino nui ake, ahakoa he iti, ka taea. * Whakatūpato Pouaka a te FDA: Kei a Wellbutrin me Lexapro hoki te whakatūpato nui rawa atu a te FDA mō te nui o te tūponotanga o ngā whakaaro me ngā mahi kaikōhuru i roto i ngā tamariki, ngā rangatahi, me ngā taitamariki (i raro i te 25 tau). He mea nui ki te tirotiro mō ngā huringa ngākau, ina koa ka tīmata te rongoā, ka huri rānei te horopeta. * Ngā Paanga Kino o Wellbutrin (Motuhake): Ko te tūponotanga nui rawa atu motuhake ki a Wellbutrin ko te nui ake o te tūponotanga o te epilepsy. Ko tēnei tūponotanga ka pā ki te horopeta, ā, ka nui ake i roto i ngā tāngata kua kitea te epilepsy, kua raru rānei i ngā mate kai pērā i te anorexia, te bulimia rānei. * Ngā Paanga Kino o Lexapro (Motuhake): Ko tētahi tūponotanga iti engari nui ki a Lexapro ko te serotonin syndrome, tētahi āhuatanga ka puta mai i te nui rawa o te serotonin. Ka puta pea tēnei ina honoa a Lexapro ki ētahi atu mea e whakanui ana hoki i te serotonin (pērā i ētahi rongoā mate upoko, St. John's Wort rānei). Ko ngā tohu ko te ngākau whakatā, te raruraru, te tere o te ngākau, me te uaua o ngā uaua.

Ka taea e koe te inu a Wellbutrin me Lexapro tahi?

Ka taea pea te ahua koretake, engari ko te whakautu ko te ae. Ko te tohutohu i te Lexapro me Wellbutrin tahi he rautaki noa, whai hua hoki e mōhiotia ana ko te maimoatanga whakapakari.

Ka taea e te tākuta te tūtohu i tēnei huinga mō ngā take e rua: 1. Hei Whakanui i te Paihere: Ki te kāore a Lexapro anake e tino whakaoti ana i ngā tohu pouri, ka taea e te tāpiri o Wellbutrin te hoatu i tētahi atu kaha mā te aro ki ngā ara dopamine me norepinephrine. Ka tino āwhina tēnei ki te whawhai ki te ngenge tonu, ki te kore rānei o te hihiri. 2. Hei Whakakore i ngā Paanga Kino: Ki te pai te mahi a te manawanui ki a Lexapro engari ka raru ia i ngā paanga kino ki te ira tangata, te ngenge, te taumaha rānei, ka taea e te tākuta te tāpiri i tētahi horopeta iti o Wellbutrin hei āwhina ki te whakaiti i ēnei raruraru.

Me tino whai i raro i te tirotiro tino kaha a te kaiwhakarato hauora mā te mātauranga e taea ai te tirotiro i ngā paanga kino me te whakarite i ngā horopeta tika.

Te Whiriwhiri: Ko Wai pea te Pai mōu?

Ko te whakatau whakamutunga kei a koe me tō tākuta, engari koinei te whakarāpopototanga hei āwhina i tērā kōrero. Kia mahara, ko te whakawhiti mai i a lexapro ki a wellbutrin (ā, ka mutu rānei) he kōwhiringa tonu mēnā kāore te kōwhiringa tuatahi e pai ana.

Whakaarohia a Lexapro mēnā…

• Ka kite koe i te pouri me te manawawhiti nui. Kua whakaaetia a Lexapro e te FDA mō te Generalized Anxiety Disorder, ā, he tino pai hoki ki te whakaputa i te ahua marino.
• He ngāwari koe ki ngā rongoā "whakahihiko" ake, ā, kei te āwangawanga koe mō te ngākau whakatā, te ohoroa rānei.
• Ko ngā tohu o tō pouri ko te ngākau pouri, te raru o te whakaaro, te whakaaro pukapuka rānei.

Whakaarohia a Wellbutrin mēnā…

• Ko ngā tohu o tō pouri ko te iti o te kaha, te ngenge, te moe nui, me te kore o te hihiri.
• He tino āwangawanga koe mō ngā paanga kino ki te ira tangata o wellbutrin, mō te taumaha o lexapro rānei.
• Kei te ngana hoki koe ki te mutu te hikareti.
• Kāore koe i whai angitu ki ngā SSRIs i mua.

Te Kupu Whakamutunga

Ko te haerenga ki te kimi i te maimoatanga tika mō te hauora hinengaro he motuhake ki ia tangata. I te Wellbutrin ki te Lexapro te whakataetae, kāore he toa whānui—engari ko te mea pai mō koe.

Ko te kīanga matua ko tēnei: Ko Lexapro he SSRI e aro ana ki te serotonin, he taputapu kaha ki te pouri me te manawawhiti, engari he nui ake te tūponotanga o ngā paanga kino ki te ira tangata me te taumaha. Ko Wellbutrin he NDRI e aro ana ki te dopamine me te norepinephrine, ka nui ake te whakahihiko, ā, ka iti rawa te tūponotanga kia puta ai ēnei paanga kino, engari he tūponotanga epilepsy tōna, ā, kāore pea e pai mō te hunga he nui te manawawhiti.

Whakamahia tēnei mōhiohio ehara i te mea hei whakatau i a koe anō, engari hei whai kōrero mōhio ake, māia, me te whai hua ki tō kaiwhakarato hauora. Tahi, ka taea e kōrua te taumaha i ngā painga me ngā huakore, ā, ka hangaia he mahere maimoatanga hei āwhina i a koe kia rite anō ki a koe.