Amyloidosis

Ko te Amyloidosis (am-uh-loi-DO-sis) he mate onge e puta ana ina hangaia he pūmua e kiia nei ko te amyloid ki roto i ngā whekau. Ka taea e tēnei hanga o te amyloid te korenga o ngā mahi tika a ngā whekau.

Ko ngā whekau ka pā pea ko te ngakau, ngā whatukuhu, te ate, te kōpū, te pūnaha io, me te pūnaha kai.

Ka puta mai ētahi momo amyloidosis me ētahi atu mate. Ka taea pea te whakapai ake o ēnei momo mā te whakaora i ētahi atu mate. Ka taea pea e ētahi momo amyloidosis te arahi ki te korenga o ngā mahi a ngā whekau e raru ai te ora.

Ka uru pea ngā maimoatanga ki te chemotherapy me ngā rongoā kaha e whakamahia ana hei whakaora i te mate pukupuku. Ka taea e ētahi atu momo rongoā te whakaiti i te hanga o te amyloid me te whakahaere i ngā tohu. Ka taea pea te whai hua ki ētahi tangata te whakawhiti whekau, te whatukuhu ranei.

Ko ētahi o te hunga e pangia ana e te amyloidosis ka pā te purpura ki a rātou—he āhuatanga tēnei e ngongo ai ngā oko toto iti te toto ki roto i te kiri. Ko te nuinga o te wā ka puta tēnei i te taha o ngā kanohi, engari ka pā hoki ki ētahi atu wāhanga o te tinana.

Ka taea e te arero nui (macroglossia) te tohu o te amyloidosis. Ka taea hoki e ia te puta mai i te taha o tōna taha.

Ka taea pea e koe te kore e kite i ngā tohu o te amyloidosis kia tae ra ano ki te mutunga o te mate. Ka rereke pea ngā tohu, kei te whakawhirinaki ki te hunga o ngā whekau e pā ana.

Ko ngā tohu me ngā tohu o te amyloidosis ka uru ki:

• Te ngenge nui me te ngoikore
• Te poto o te manawa
• Te ngawari, te wiri, te mamae rānei o ngā ringa, o ngā waewae rānei
• Te pupuhi o ngā turi me ngā waewae
• Te ruaki, pea me te toto, te kōpuku rānei
• Te arero nui, ka puta mai i te taha o tōna taha
• Ngā huringa o te kiri, pēnei i te mātotoru, te ngawari o te whākū, me ngā kōwae puru i te taha o ngā kanohi

Tena tirohia tō kaiwhakarato hauora mena ka kitea e koe tetahi o ngā tohu rānei o ngā tohu e hono ana ki te amyloidosis.

He maha ngā momo amyloidosis rerekē. Ko ētahi momo he kua whatiwhati. Ko ētahi atu i puta mai i ngā take o waho, pēnei i ngā mate mumura, i te dialysis roa. He maha ngā momo e pā ana ki ngā whekau maha. Ko ētahi atu e pā ana ki tētahi wāhanga o te tinana anake.

Ko ngā momo amyloidosis e whai ake nei:

• AL amyloidosis (amyloidosis mekameka rama immunoglobulin). Koinei te momo amyloidosis tino noa i ngā whenua whānui. Ka kiia hoki te AL amyloidosis ko te amyloidosis matua. E pā ana te nuinga ki te ngakau, ngā whatukuhu, te ate me ngā io.
• AA amyloidosis. Ka kiia hoki tēnei momo ko te amyloidosis tuarua. E whakaohotia ana e te mate mumura, pēnei i te mate rewiti rheumatoid. Ko te nuinga o te wā e pā ana ki ngā whatukuhu, te ate me te kōpū.
• Amyloidosis kua whatiwhati (amyloidosis whānau). Ko tēnei mate i whakawhiwhia mai e te mātua e pā ana ki ngā io, te ngakau me ngā whatukuhu. Ko te nuinga o te wā ka puta mai ina he rerekē te pūmua i hangaia e tō ate. Ka kiia tēnei pūmua ko te transthyretin (TTR).
• Amyloidosis momo-māori. Kua kiia hoki tēnei momo ko te amyloidosis pūnaha koroheke. Ka puta mai ina he noa te pūmua TTR i hangaia e te ate, engari ka whakaputa i te amyloid mō ngā take kaore i te mōhiotia. Ko te amyloidosis momo-māori e pā ana ki ngā tāne neke atu i te 70 tau te pakeke, ā, e āta whakaaro ana ki te ngakau. Ka taea hoki te whakaoho i te mate huānga carpal.
• Amyloidosis rohe. Ko tēnei momo amyloidosis e tino pai ana te whakaora i ngā momo e pā ana ki ngā pūnaha whekau maha. Ko ngā wāhi noa mō te amyloidosis rohe ko te putea, te kiri, te korokoro, te manawa rānei. He mea nui te whakatau tika kia taea ai te karo i ngā maimoatanga e pā ana ki te tinana katoa.

Ngā take e piki ai te tūponotanga o te amyloidosis e whai ake nei:

• Tau. Ko te nuinga o te hunga kua tōmua te amyloidosis kei waenganui i ngā tau 60 me te 70.
• Ira tangata. Ka tōmua ake te amyloidosis ki ngā tāne.
• Ētahi atu mate. Ko te whai i te mate pāwera roa, mate mumura rānei, ka piki ake te tūponotanga o te AA amyloidosis.
• Hītori whānau. He uri tetahi momo amyloidosis.
• Dialysis whatukuhu. Kāore e taea e te dialysis te tango i ngā pūmua nui atu i te toto. Ki te mea kei runga koe i te dialysis, ka taea e ngā pūmua rerekē te hanga ki roto i tō toto ka mutu ka whakatārewatia ki roto i te kiko. He iti ake te noho o tēnei āhuatanga me ngā tikanga dialysis hou ake.
• Iwi. E kite ana te iwi o Awherika kei te piki ake te tūponotanga o te mau i te tauira ira e hono ana ki tetahi momo amyloidosis e taea te kino ki te ngakau.

Ka taea e te Amyloidosis te kino nui ki te:

• Ngā ngākau. Ka whakaiti te Amyloid i te kaha o te ngākau ki te whakaki i te toto i waenganui i ngā whiu o te ngākau. Ka iti ake te toto e pupū ana i ia whiu. Ka taea e tēnei te pāngia e te poto o te manawa. Ki te pā te amyloidosis ki te pūnaha hiko o te ngākau, ka taea e ia te pāngia e ngā raruraru o te taurite o te ngākau. Ka taea e ngā raruraru o te ngākau e pā ana ki te Amyloid te riro hei mate kino.
• Ngā whatukuhu. Ka taea e te Amyloid te kino ki te pūnaha kānana o ngā whatukuhu. Ka pā tēnei ki to rātou kaha ki te tango i ngā hua paru i roto i te tinana. Ka taea e ia te pāngia e te kore mahi o ngā whatukuhu.

Kaore he uauatanga

Ko te amyloidosis te nuinga o te wā ka tirohia, nā te mea ka rite ngā tohu me ngā tohu ki ētahi atu mate tino noa. Ka taea e te whakamātautau wawe te āwhina i te aukati i te kino atu o ngā kōpū. He mea nui te whakamātautau tika, nā te mea ka rereke te rongoā, kei runga i tō āhuatanga motuhake. Ngā whakamātautau taiwhanga Ka taea te tātari i te toto me te mimi mō te pūmua rerekē ka taea te tohu i te amyloidosis. Ka hiahia pea ētahi atu tangata ki ngā whakamātautau mahi o te thyroid me te whatukuhu. Biopsy Ka taea te tirotiro i te tauira kiko mō ngā tohu o te amyloidosis. Ka taea te tango i te biopsy mai i te ngako kei raro i te kiri o te kopu, i te wheua wheua rānei. Ka hiahia pea etahi atu tangata ki te biopsy o te kōpū kua pā, pēnei i te ate, i te whatukuhu rānei. Ka taea te whakamātautau i te kiko kia kite he aha te momo amyloid e pā ana. Ngā whakamātautau whakaahua Ka uru ngā whakaahua o ngā kōpū kua pā te amyloidosis ki: Echocardiogram. Ka whakamahi tēnei hangarau i ngā ngaru oro hei hanga i ngā whakaahua nekehanga ka taea te whakaatu i te pai o te mahi o te ngakau. Ka taea hoki te whakaatu i te kino o te ngakau ka taea te motuhake ki ētahi momo amyloidosis. Magnetic resonance imaging (MRI). Ka whakamahi te MRI i ngā ngaru reo me te mara hiko kaha hei hanga i ngā whakaahua taipitopito o ngā kōpū me ngā kiko. Ka taea te whakamahi i ēnei hei tirotiro i te hanganga me te mahi o te ngakau. Nuclear imaging. I roto i tēnei whakamātautau, ka werohia ngā rahinga iti o te rauemi pāpāho (tracers) ki roto i te uaua. Ka taea e tēnei te whakaatu i te kino o te ngakau i te timatanga i puta mai i ētahi momo amyloidosis. Ka taea hoki te āwhina i te wehewehe i waenga i ngā momo amyloidosis rerekē, ka taea te arahi i ngā whakatau rongoā. Ngā tiaki i te Mayo Clinic Ka taea e tā tātou rōpū manaaki o ngā tohunga o te Mayo Clinic te āwhina i a koe ki ō kōrero hauora e pā ana ki te amyloidosis Tīmata konei Ētahi atu mōhiohio Ngā tiaki amyloidosis i te Mayo Clinic Urinalysis

Kāore he rongoā mō te amyloidosis. Engari ka taea e te maimoatanga te awhina i te whakahaere i ngā tohu me ngā tohu, ā, te whakaiti i te whakaputa atu o te pūmua amyloid. Ki te mea kua whakaohohia te amyloidosis e tētahi atu āhuatanga, pēnei i te mate rewiti rheumatoid, te mate huhu rānei, ka taea te awhina te whakaora i te āhuatanga taketake.

• Kemoterapi. Ka whakamahia etahi rongoā mate pukupuku ki te amyloidosis AL hei mutu i te tipu o ngā pūtau koretake e whakaputa ana i te pūmua e hanga ana i te amyloid.
• Rongoā ngākau. Ki te pā te ngākau, me inu pea koe i ngā kaiwhakaraupapa toto hei whakaiti i te tūponotanga o ngā kōwhiti. Me inu pea hoki koe i ngā rongoā hei whakahaere i tō tere ngākau. Ka taea e ngā rongoā e whakapiki ana i te mimi te whakaiti i te ahotea ki tō ngākau me ō whatukuhu.
• Ngā maimoatanga e taea ana. Mō ētahi momo amyloidosis, ka taea e ngā rongoā pēnei i te patisiran (Onpattro) me te inotersen (Tegsedi) te whakakore i ngā whakahau i tukuhia e ngā ira kino e hanga ana i te amyloid. Ko ētahi atu rongoā, pēnei i te tafamidis (Vyndamax, Vyndaqel) me te diflunisal, ka taea te whakau i ngā wahi o te pūmua i roto i te toto, ā, te aukati i te huri ki ngā tāpiringa amyloid.
• Nekehanga pūtau pūtau toto autologous. Kei roto i tēnei tukanga te kohikohi i ō ake pūtau pūtau mai i tō toto mā tētahi uaua, ā, te penapena mō tētahi wā poto i te wā e nui ana te kemoterapi. Katahi ka whakahokia ngā pūtau pūtau ki tō tinana mā tētahi uaua. Ko tēnei maimoatanga te mea tino tika mō te hunga kāore i tino whanake o rātou mate, ā, kāore hoki o rātou ngākau i pā kino rawa.
• Dialysis. Ki te pā kino ō whatukuhu i te amyloidosis, me tīmata pea koe ki te dialysis. Ka whakamahi tēnei tukanga i tētahi mīhini hei kānana i ngā paru, ngā tote me te wai mai i te toto i runga i te kaupapa noa.
• Nekehanga whekau. Ki te mea kua kino rawa te pā o ngā tāpiringa amyloid ki tō ngākau, ki ō whatukuhu rānei, me mahi pea koe i te pokanga hei whakakapi i aua whekau. Ka hangaia etahi momo amyloid i roto i te ate, na reira ka taea e te nekehanga ate te mutu i taua whakaputanga.

Kaore he uauatanga