He aha te Pemphigus? Tōna Tohutohu, Ngā Take, me te Rongoā

Ko te pemphigus he mate ā-tinana onge e whakaeke ana te pūnaha ā-mate o tō tinana ki ngā kiri hauora me ngā kiri ngawha. Ka puta mai tēnei whakaeke i ngā pupuhi mamae me ngā pōka ki tō kiri, ki roto i tō waha, i tō korokoro rānei, i ētahi atu wāhi kei reira ngā kiri ngawha.

Ahakoa e rangona ana te wehi o te pemphigus, ka taea e te mārama ki te aha ia me te āhua o tōna mahi te awhina i a koe kia mōhio ake. Ko tō pūnaha ā-mate, e tiaki ana i a koe i ngā mate, ka pohehe ka tīmata ki te whakaeke i ngā pūmua e pupuri ana i ngā pūtau o tō kiri. Ka ngoikore enei hononga, ka puta mai ngā pupuhi kī kua ki tonu i te wai ka taea te mamae me te ngāwari te pakaru.

He aha ngā tohu o te pemphigus?

Ko te tohu tino kitea o te pemphigus ko te puta mai o ngā pupuhi ngawari, kua ki tonu i te wai, e puta ana ki te kiri noa. He tino pakaru enei pupuhi, ka ngāwari te pakaru, ka waiho i ngā wāhi mamae, kua pakaru, ka roa te ora.

Tātou e haere tahi ana i ngā tohu ka pā pea ki a koe, kia mahara ko te wheako o te tangata, he rerekē.

• Ngā pupuhi mamae e tīmata ana i tō waha, i tō korokoro rānei, i runga i tō pane rānei i mua i te horapa ki ētahi atu wāhi
• Te kiri pakaru e puta ana te wehe atu, te marere rānei ina tukuna he pēhanga ngawari
• Ngā pōka kua pakaru, kua rere te wai i ngā pupuhi kua pakaru
• Te uaua ki te kai, ki te horomia rānei ina puta mai ngā pupuhi i tō waha, i tō korokoro rānei
• Ngā wāhi kua hipoki i tō kiri kei te ngana te ora
• Te pāwera, te wera rānei i ngā wāhi kua pā

I roto i ngā take onge, ka puta mai ngā pupuhi ki ētahi i o rātou kanohi, ihu, i ngā wāhi ira tangata rānei. Ka rerekē te tauira me te kaha mai i te tangata ki te tangata. Ko te mea nui ko te mohio kei te tika ngā tohu nei ki te tiaki hauora, ina koa ki te mau tonu, ki te kino ake rānei i te wā.

He aha ngā momo pemphigus?

He maha ngā momo pemphigus, ia momo ka pā ki tō tinana i ngā huarahi iti te rerekē. Ko ngā momo matua ka wehea e te wāhi e puta mai ana ngā pupuhi me te hohonu o te tomo ki roto i ngā paparanga o tō kiri.

Ko te pemphigus vulgaris te momo tino noa ka kitea. Ka tīmata ia ki ngā pupuhi mamae i roto i tō waha i mua i te horapa ki tō kiri. Ka puta enei pupuhi i roto i ngā paparanga hohonu o tō kiri, ka tino pakaru, ka puhoi te ora.

Ko te pemphigus foliaceus ka pā ki ngā paparanga o runga o tō kiri, ka iti rawa te pā ki tō waha, ki ngā kiri ngawha rānei. Ka iti ake te hohonu o ngā pupuhi, ka rite ki ngā wahi kua hipoki, kua tautau rānei i te wāhi o ngā pōka hohonu i kitea i te pemphigus vulgaris.

Ko ngā momo iti ake te noa ko te pemphigus vegetans, kei reira ngā tipu mātotoru, kikī e puta ana i ngā kopiko kiri, me te paraneoplastic pemphigus, ka taea te puta tahi me ētahi mate pukupuku. Ka taea te puta mai te pemphigus i runga i te rongoā hei whakautu ki ngā rongoā motuhake, ahakoa ka ngaro tēnei ina mutu te rongoā whakaohooho.

He aha ngā take o te pemphigus?

Ka puta te pemphigus ina hanga e tō pūnaha ā-mate ngā antibodies e whakaeke ana ki ngā pūmua e kiia nei ko te desmogleins. Ko ēnei pūmua te mahi rite ki te piripiri molecular, e pupuri ana i ngā pūtau o tō kiri kia piri tahi ai hei hanga i te parepare.

Kāo te take tino tika he aha i pohehe ai tō pūnaha ā-mate kāore anō kia tino mārama. E whakapono ana ngā kairangahau pea he whakakotahitanga o ngā take ira e whakapakari ana i a koe me ngā whakaohooho taiao pea ka whakahohe i te mate.

He maha ngā take ka taea te whakaohooho i te pemphigus ki ngā tāngata kei te whakapae ira:

• Ētahi rongoā, tae atu ki ngā ACE inhibitors, ngā antibiotics penei i te penicillin, me ētahi rongoā mamae
• Ngā mate huaketo pea ka pohehe tō pūnaha ā-mate
• Te ahotea nui o te hinengaro, o te tinana rānei
• Te whakamahinga ki ētahi kemikara, poihana rānei
• Ētahi atu mate ā-tinana pea ka piki ake tō tūponotanga

I roto i ngā take onge, ka taea te puta mai te pemphigus tahi me ngā mate pukupuku, ina koa ētahi momo lymphoma. Ko tēnei momo, e kiia nei ko te paraneoplastic pemphigus, ka taea te pai ake ina ora pai te mate pukupuku.

Nōhea te haere ki te taote mō te pemphigus?

Me haere wawe koe ki te taote ki te puta mai ngā pupuhi, ngā pōka rānei kāore e ora i roto i ngā rā torutoru, ina koa ki te puta mai rātou i tō waha, ki te horapa atu rānei ki ngā wāhi maha o tō tinana. Ka taea e te whakamārama me te rongoā wawe te āwhina i te aukati i ngā raruraru me te whakaiti i te mamae.

Rapua te tiaki hauora wawe ki te pā te uaua ki te horomia, ngā raruraru manawa rānei, ngā tohu rānei o te mate whānui penei i te kirika, te wiri, te whero tere rānei e horapa ana i ngā taha o ō pōka. Ka taea e ēnei tohu te tohu kei te pā te mate ki ngā mahi nui, kei te puta mai rānei ngā mate tuarua.

Kaua e tatari ki te kite koe kei te tīmata te wehe atu, te marere rānei o tō kiri me te pēhanga ngawari, i te mea pea he tohu tēnei o te pemphigus nui e hiahia ana ki te rongoā wawe. Ka taea e tō taote te mahi i ngā whakamātautau motuhake hei whakau i te whakamārama me te tīmata i te rongoā tika hei awhina i ō tohu kia pai ake.

He aha ngā take tūponotanga mō te pemphigus?

Ka taea e ētahi take te piki ake i tō tūponotanga ki te whiwhi pemphigus, ahakoa te whai i ēnei take tūponotanga kāore e tikanga ka whiwhi koe i te mate. Ka taea e te mārama ki a rātou te āwhina i a koe kia mōhio ki ngā tohu pea.

Koinei ngā take matua kua kitea e te rangahau:

• Te tau i waenga i te 40 me te 60 tau, ahakoa ka taea te puta i tetahi tau
• Te tīpuna Hūrai, te Moana Whenua rānei, ina koa te tīpuna Hūrai Ashkenazi
• Te hītori whānau o ngā mate ā-tinana
• Te tango i ētahi rongoā e mohiotia ana hei whakaohooho i te pemphigus
• Te whai i ētahi atu mate ā-tinana penei i te mate rheumatoid, te lupus rānei
• Te whakamahinga ki ngā poihana taiao motuhake rānei

I roto i ngā take onge rawa, he mahi tika ake ngā take ira, me ētahi momo ira HLA e whakapakari ana i ētahi tāngata. Heoi, ahakoa te whakapae ira, kāore te nuinga o te iwi e whiwhi pemphigus, e tohu ana ko ngā whakaohooho taiao te tikanga kia whakahohe i te mate.

He aha ngā raruraru pea o te pemphigus?

Ahakoa ka taea te whakahaere i te pemphigus me te rongoā tika, ka taea te puta mai ngā raruraru maha ki te kore e whakahaere pai te mate. Ko te take matua ko ngā mate huaketo tuarua i roto i ngā pōka tuwhera kei reira ngā pupuhi kua pakaru.

Tātou e haere tahi ana i ngā raruraru me āta whakaaro:

• Ngā mate kiri ka taea te horapa ki te tomo ngā huaketo i roto i ngā pupuhi kua pakaru
• Te tohu i ngā wāhi kua ora ngā pōka hohonu
• Te ngau wai mai i te ngaro wai i te kino o te kiri
• Ngā raruraru kai ki te uaua te kai i ngā pōka waha
• Ngā koretake o te electrolyte mai i te ngaro wai me ngā kohuke
• Ngā wero pāpori me te hinengaro mai i ngā huringa kiri e kitea ana

I roto i ngā take nui, kino rānei, ka taea e te pemphigus whānui te arahi ki ngā raruraru kino e rite ana ki ngā tahuna nui, tae atu ki ngā mate nui, te kore mahi o ngā whekau rānei. Hei tāpiri atu, ko ētahi o ngā rongoā e whakamahia ana hei whakaora i te pemphigus ka taea te whai i ō rātou pānga taha, ka āta tirotirohia e tō taote i te wā o te rongoā.

Me pēhea te whakamārama i te pemphigus?

Ko te whakamārama i te pemphigus e hiahia ana ki ngā whakamātautau motuhake na te mea ka rite te ahua o te mate ki ētahi atu mate kiri pupuhi. Ka tīmata tō taote me te tirotiro tika o tō kiri me te ui i ngā pātai taipitopito mo te wā me te āhua o te tīmatanga o ō tohu.

Ko te whakamātautau whakamārama tino nui ko te biopsy kiri, kei reira tō taote e tango ana i te tauira iti o te kiri kua pā mō te tātaritanga taiwhanga. E rua ngā momo biopsy e mahia ana: tētahi mō te tirotiro noa i raro i te microscope, tētahi atu mō te whakamātautau immunofluorescence tika.

Ko te whakamātautau immunofluorescence tika e titiro ana ki ngā antibodies motuhake e puta mai ana te pemphigus. Ka taea e tēnei whakamātautau te whakaatu i te tauira tohu o ngā tāpiringa antibody i waenga i ngā pūtau kiri, e āwhina ana ki te whakau i te whakamārama me te wehe i te pemphigus i ētahi atu mate.

Pea ka tono atu tō taote ngā whakamātautau toto hei ine i ngā taumata o ngā antibodies pemphigus i roto i tō toto. Ko ēnei whakamātautau, e kiia nei ko ngā whakamātautau immunofluorescence kore tika, ngā whakamātautau ELISA rānei, ka taea te āwhina ki te tirotiro i te kaha o tō mate me te pai o te mahi o te rongoā.

He aha te rongoā mō te pemphigus?

Ko te rongoā mō te pemphigus e aro ana ki te whakaiti i tō pūnaha ā-mate nui hei aukati i ngā pupuhi hou mai i te puta mai me te āwhina i ngā pōka o nāianei kia ora.

Ko ngā rongoā matua e whakamahia ana ko ngā corticosteroids me ētahi atu rongoā whakaiti-mate e taea ai te whakahaere pai i te mate.

Pea ka whai tō mahere rongoā i ngā huarahi maha e mahi tahi ana:

• Ngā corticosteroids waha hei whakahaere tere i te mate kaha
• Ngā rongoā whakaiti-mate penei i te methotrexate, te azathioprine rānei hei whakaiti i te whakawhirinaki ki te steroid
• Ngā rongoā o runga hei āwhina i te ora i ngā pōka o nāianei me te aukati i te mate
• Ngā antibiotics ki te puta mai ngā mate huaketo tuarua
• Rituximab mō ngā take nui kāore e whakautu ki ngā rongoā noa
• Plasmapheresis hei tango i ngā antibodies kino i tō toto i ngā āhuatanga ohorere

I roto i ngā take nui, te kore rongoā rānei, pea ka whakaarohia ngā rongoā hou o te tikanga ora, te rongoā immunoglobulin intravenous rānei. Ka mahi tahi tō taote me koe hei kimi i te whakakotahitanga tika o ngā rongoā e whakahaere ana i ō tohu me te whakaiti i ngā pānga taha.

Me pēhea te whakahaere i te pemphigus i te kāinga?

Ko te tiaki i a koe i te kāinga he wāhi nui ki te whakahaere i te pemphigus tahi me tō rongoā hauora. Ko te tiaki kiri ngawari me te tiaki i tō kiri pakaru mai i te kino atu ka taea te āwhina i te aukati i ngā raruraru me te whakapai ake i tō māramatanga.

Kia ma, kia maroke tō kiri, engari kia kaua e whakamahi i ngā haupae kino, te horoi rānei ka taea te kino i ngā wāhi pakaru.

Koinei ngā mahi whai hua ka taea e koe te mahi i ia rā:

• Whakamahia ngā rongoā o runga kua tohua kia rite ki te tohutohu
• Whakamahia ngā whakauru kiri ngawari, kāore he kakara hei pupuri i te hauora o te kiri kāore i pā
• Kakahu kakahu ngawari, huruhuru kore hei karo i te riri ki tō kiri
• Kai kai ngawari, kāore he piripiri ki te whai koe i ngā pōka waha
• Kia makona te inu wai, ina koa ki te whai koe i te kiri whānui
• Karohia ngā mahi ka taea te whakaohooho i te kiri, te whara rānei

Tirohia ngā tohu o te mate penei i te piki o te whero, te wera, te pū, te whero rānei e horapa ana i ngā taha o ō pōka. Whakapa atu ki tō kaiwhakarato hauora tonu ki te kite koe i ēnei huringa, i te mea he mea nui te rongoā wawe o ngā mate mō ngā tāngata e whai ana i te pemphigus.

Me pēhea te whakarite mō tō hui taote?

Ko te whakarite mō tō hui ka taea te āwhina i te whakarite ka whiwhi koe i te tiaki whānui rawa. Kawe mai he rārangi o ngā rongoā katoa e tangohia ana e koe inaianei, tae atu ki ngā rongoā-ā-kaute me ngā taapiri, i te mea ka taea e ētahi te whakaohooho, te kino rānei i te pemphigus.

Tuhia te wā i puta tuatahi mai ai ō tohu me te āhua o te huringa i te wā. Tātaihia ngā whakaohooho pea ka taea e koe te mahara, penei i ngā rongoā hou, ngā mate, ngā kaupapa ahotea rānei i puta i mua i te tīmatanga o ō tohu.

Tātaihia ngā whakaahua marama o ngā wāhi kua pā ki te taea, ina koa ki te puta mai, te ngaro rānei ō tohu i te wā. Ka taea e tēnei tuhinga whakairoiro te āwhina i tō taote ki te mārama ki te tauira me te kaha o tō mate ahakoa kāore ngā tohu e kaha ana i te wā o tō haerenga.

Whakaritea ngā pātai mō tō mate, ngā whiringa rongoā, me te aha ka tumanakohia e haere tonu ana. Kaua e whakaroa ki te ui mō ngā pānga taha o ngā rongoā e whakatakotoria ana me te āhua o te tirotiro i tō ahunga whakamua i te wā.

He aha te mea nui mō te pemphigus?

Ko te pemphigus he mate ā-tinana nui engari ka taea te whakaora e hiahia ana ki te tiaki hauora tonu me te manawanui i a koe me tō rōpū hauora e kimi ana i te huarahi rongoā tika. Me te rongoā tika, ka taea e te nuinga o te iwi te whiwhi i te whakahaere pai o ō rātou tohu me te pupuri i te kounga ora pai.

Ko te kī ki te whakahaere angitu ko te whakamārama wawe, te rongoā tonu, me te mahi tata me ngā kaiwhakarato hauora e mārama ana ki tēnei mate uaua. Ahakoa ka taea e te pemphigus te rangona he nui te pānga i te tīmatanga, kia mahara kei reira ngā rongoā whai hua, a he maha ngā tāngata e ora ana i te ora katoa, te mahi kaha i te wā e whakahaere ana i tēnei mate.

Noho hono atu ki tō rōpū hauora, whai i tō mahere rongoā kia tika, kaua hoki e whakaroa ki te whakapa atu ina whai koe i ngā pātai, i ngā awangawanga rānei. Me te wā me te tiaki tika, ka taea e koe te ako ki te whakahaere i te pemphigus kia pai me te aro ki ngā mea nui rawa atu ki a koe.

Ngā pātai e ui pinepinetia ana mō te pemphigus

P1: He mate ka taea te horapa te pemphigus?

Kāo, kāore te pemphigus e taea te horapa. Kāore e taea te hopu mai i tētahi atu, te horapa atu rānei ki ētahi atu tāngata mā te hononga. He mate ā-tinana e puta ana ina whakaeke he tō pūnaha ā-mate ake ki tō kiri, ehara i te mate e puta mai ana i ngā huaketo, i ngā huaketo rānei.

P2: Ka taea te whakaora katoa te pemphigus?

I tēnei wā, kāore he rongoā mō te pemphigus, engari ka taea te whakahaere pai te mate me te rongoā tika. Ka whiwhi te nuinga o te iwi i te whakaora roa kei reira kāore he tohu kaha mō ngā marama, ngā tau rānei. Ka taea e ētahi tāngata te whakaiti, te mutu rānei i ō rātou rongoā i te wā e pupuri ana i te whakahaere pai, ahakoa e hiahia ana tēnei ki te tirotiro hauora ata.

P3: Me tango rongoā tonu ahau mō te toenga o toku ora?

Kāore pea. Ahakoa e hiahia ana ētahi tāngata ki te rongoā roa hei pupuri i tō rātou pemphigus i raro i te whakahaere, ka taea e ētahi atu te whakaiti i ō rātou rongoā i te wā me te mutu i ngā rongoā i te wā e noho tonu ana i te whakaora. Ka whakawhirinaki ō hiahia rongoā takitahi ki te āhua o te whakautu o tō tinana ki te rongoā me te āhua o te pumau o tō mate.

P4: Ka taea e ngā huringa kai te āwhina i te pemphigus?

Ahakoa kāore he kai pemphigus motuhake ka taea te whakaora i te mate, ko te kai pai ka taea te tautoko i tō hauora whānui me te ora. Ki te whai koe i ngā pōka waha, ko te karo i ngā kai piripiri, waikawa rānei ka taea te whakaiti i te mamae. Ka kite ētahi i te ahua o te whakaohooho i ētahi kai, ahakoa he rerekē tēnei mai i te tangata ki te tangata.

P5: He mea tika te hapu ki te whai ahau i te pemphigus?

He maha ngā wāhine e whai ana i te pemphigus ka taea te hapu angitu, engari e hiahia ana ki te whakamahere me te tirotiro ata me tō dermatologist me tō obstetrician. Me whakarereke, me whakarerekē rānei ētahi rongoā pemphigus i te wā o te hapu, a pea ka rereke tō mate i te wā o te hapu me muri i te hapu. He mea nui te ui wawe ki tō rōpū hauora mō te whakamahere.