He aha te Abatacept: Ngā Whakamahinga, te Inenga, Ngā Pānga Taha me Ētahi Atu

Ko te Abatacept he rongoā rongoā e āwhina ana ki te whakamārie i te pūnaha ārai mate e kaha rawa ana, mō te hunga e mate ana i te rūmātiki me ētahi atu āhuatanga ārai mate. Whakaarohia he pūtu ngawari mō tō pūnaha ārai mate i te wā e whakaeke ana i ō kiko hauora.

E rua ngā momo o tēnei rongoā: ngā whakaurunga i roto i te uaua (IV) e whakawhiwhia ana i te whare rongoā, me ngā werohanga i raro i te kiri ka taea e koe te whakawhiwhi i a koe i te kāinga. E mahi ana ngā momo e rua i te ara kotahi engari e tuku ana i ngā taumata rerekē o te watea i runga i tō oranga me ō hiahia rongoā.

He aha te Abatacept?

Ko te Abatacept he rongoā koiora nō te akomanga e kiia nei ko ngā kaiwhakawāhi kōwhiri. E mahi ana mā te aukati i ētahi tohu i waenga i ngā pūtau ārai mate e pā ana ki te mumura me te kino o te hononga.

Kāore i rite ki ētahi atu rongoā ārai mate kaha ake, he huarahi whāinga ake te abatacept. Kāore e kati ana i tō pūnaha ārai mate katoa engari e whakatikatika ana i ngā ara motuhake e whai wāhi ana ki ngā mate ārai mate. Mā tēnei ka waiho hei kōwhiringa ngawari ake i te wā e whai hua tonu ana.

I hangaia te rongoā mai i ngā pūmua me te tika kia noho i roto i te pouaka whakamātao. Kua whakaaetia e te FDA mai i te tau 2005, ā, kua āwhina i miriona tāngata ki te whakahaere i ō rātou āhuatanga ārai mate i te pai ake.

He aha te Abatacept e whakamahia ana?

Ko te Abatacept te mea nui e tohua ana mō te rūmātiki i ngā pakeke me ngā tamariki neke atu i te 6 tau te pakeke. Kua whakaaetia hoki mō te rūmātiki psoriatic me te rūmātiki idiopathic juvenile.

Ka tūtohu pea tō tākuta i te abatacept i te wā kāore anō ētahi atu rongoā i whai hua, i te rānei hei rongoā tuatahi i ētahi wā. He tino āwhina mō te hunga e pā ana ki te mārō nui o te ata, te pūhi o te hononga, me te ngenge mai i tō rātou āhuatanga ārai mate.

E whakamahi ana ētahi tākuta i te abatacept i waho i te tapanga mō ētahi atu āhuatanga autoimmune pēnei i te lupus, ētahi momo vasculitis rānei. Heoi, kei runga tēnei i tō āhuatanga motuhake me te hītori hauora.

Me pēhea te mahi a Abatacept?

Ka mahi a Abatacept mā te aukati i tētahi pāhekoheko motuhake i waenga i ngā pūtau ārai mate e kīia ana ko ngā pūtau T me ngā pūtau whakaatu-antigen. Ki te kōrero hē ēnei pūtau, ka whakaoho rātou i te mumura e whakangaro ana i ō hononga me ō kiko.

Ka mahi te rongoā nei hei kaiwawao ngawari, e ārai ana i ēnei kōrero kino i waenga i ngā pūtau ārai mate me te kore e whakakore rawa i te kaha o tō tinana ki te whawhai i ngā mate. Ko tēnei huarahi whāinga te take i whakaarohia ai te abatacept he rongoā kaha-āhua, kaua ki te rongoā ārai mate kaha.

Ka tīmata pea koe ki te kite i ngā whakapainga i roto i te 2-3 marama, ahakoa ka kite ētahi tāngata i ngā painga i mua. Ko te katoa o ngā pānga ka puta i roto i te 6 marama i te mea ka whakaheke haere te rongoā i te mumura puta noa i tō tinana.

Me pēhea taku tango i te Abatacept?

Ko te huarahi e tango ai koe i te abatacept kei runga i te puka i tohua e tō tākuta. Ka hoatu ngā whakaurunga IV ki tētahi whare hauora i roto i te 30 meneti pea, ā, ka taea te mahi i ngā werohanga i raro i te kiri i te kāinga.

Mō te maimoatanga IV, ka whiwhi koe i ngā whakaurunga i ngā wiki 2, 4 wiki, kātahi ka 4 wiki i muri i tō horopeta tuatahi. Kāore koe e hiahia ki te nohopuku i mua, engari ko te noho pai te wai ka āwhina i a koe kia pai ake te ngākau i te wā o te whakaurunga.

Mēnā kei te whakamahi koe i te puka i raro i te kiri, ka werohia e koe kotahi i te wiki, te nuinga i tō huha, puku, ringa rānei o runga. Mā tō rōpū hauora koe e ako i te tikanga werohanga tika me te huri i ngā wāhi werohanga hei ārai i te riri.

E pai ana ngā puka e rua, nō reira ko te kōwhiringa ka heke iho ki tō hiahia mō te watea ki te whakapūmau rānei o te tirotiro hauora. E pai ana ētahi tāngata ki ngā werohanga kāinga ā-wiki mō te ngāwari, i te mea e pai ana ētahi atu ki ngā haerenga ā-marama ki te whare haumanu mō te aroturuki tonu.

Kia Pēhea Te Roa e Tango Ana ahau i te Abatacept?

Ko te Abatacept te tikanga he rongoā wā-roa, ko te tikanga ka haere tonu koe ki te tango i te rongoā i te wā e whai hua ana ki tō āhuatanga, ā, kāore e puta he pānga kino nui. Ko te nuinga o te tāngata e tango ana i te rongoā mō ngā tau, kaua mō ngā marama.

Ka aroturukihia e tō tākuta tō urupare i ngā marama 3-6 katoa hei aromatawai mēnā kei te whai hua tonu te rongoā. Mēnā kua pai te whakahaere i ō tohumate, ā, kāore koe e pā ana ki ngā pānga kino e raru ana, ko te haere tonu i te rongoā te tikanga ka puta ngā hua pai.

Tētahi wā, me mutu te tango mō tētahi wā poto mēnā ka puta ētahi mate, me hiahia rānei ki te pokanga. Mā tō tākuta koe e ārahi i ngā okiokinga e tika ana, ā, ka āwhina i a koe ki te tīmata anō i te wā e tika ana.

He Aha ngā Pānga Kino o te Abatacept?

He pai te whakamanawanui a te nuinga o te tāngata ki te abatacept, engari pērā i ngā rongoā katoa, ka puta pea he pānga kino. Mā te māramatanga ki ngā mea e tūmanakohia ana ka āwhina i a koe kia māia ake mō tō rongoā.

Ko ngā pānga kino noa he ngawari, ā, he pai te whakahaere. Ko ēnei urupare o ia rā, o ia rā e pā ana ki te nuinga o te tāngata, engari kāore e hiahiatia te mutu i te rongoā:

• Te mamae o te upoko me te ngenge ngawari
• Ngā mate o te ara rererangi o runga pērā i te makariri
• Te whakapairuaki, te puku rānei
• Ngā urupare i te wāhi werohanga (te whero, te pūpū, te mamae ngawari rānei)
• Te whanoke i te wā, i muri rānei i ngā whakawhiwhinga IV

Ko ēnei pānga kino noa ka pai ake i te wā e urutau ana tō tinana ki te rongoā i ngā wiki, i ngā marama tuatahi rānei.

Ko ngā pānga kino nui ake he iti noa iho te puta, engari me whai whakaaro tonu. Ahakoa he onge, me aromatawai tonu ēnei āhuatanga:

• Ngā tohu o te mate nui (te kirika, te wiri, te mare tonu, te ngenge rerekē)
• Ngā urupare pānga kino nui (te uaua ki te hā, te pūpū, te rāwaho nui)
• Te toto rerekē, te pāpā rānei
• Te whakapairuaki tonu, te ruaki, te mamae o te puku
• Ngā whara kiri hou, e kino ake ana rānei

Ko te rongo pai ko te iti iho i te 5% o nga tangata e tango ana i te abatacept ka pa ki nga paanga kino, a ka taea te whakahaere i te nuinga i te wa e kitea wawe ana.

Ko wai e kore e tango i te Abatacept?

Ehara te Abatacept i te mea tika mo te katoa, a ko etahi ahuatanga hauora ka kore e tika, ka hiahia ranei kia tupato. Ka ata titiro to taakuta ki to hitori rongoa i mua i te whakahau.

Kaua koe e tango i te abatacept mena he mate kino koe, tae atu ki te mate kohi, mena kua pa ki a koe nga tauhohenga mate pāwera nui ki te rongoa i mua. Ko nga tangata e mate ana i etahi momo mate pukupuku ka hiahia pea ki te karo, ki te tatari ranei kia oti ra ano to ratou maimoatanga.

He mea nui te tupato mena he hitori koe mo nga mate e hoki mai ana, te hepatitis B, C ranei, etahi ahuatanga ranei o te pūkahukahu. Tera pea ka tono to taakuta i etahi atu whakamatautau me te aroturuki mena kei a koe enei ahuatanga engari kei te hiahia tonu koe ki te abatacept.

Me matapaki nga wahine hapu, nga wahine e whangai ana i te u i nga tupono me nga painga ki to ratou taakuta, na te mea kaore i te tino marama nga paanga ki nga pepi e tipu ana.

Nga Ingoa Waitohu Abatacept

Ka hokona te Abatacept i raro i te ingoa waitohu Orencia i roto i nga momo IV me te subcutaneous. Koinei te ingoa tino noa ka kite koe i runga i nga whakahaunga me nga tuhinga inihua.

I tenei wa kaore he putanga whanui o te abatacept e waatea ana, na te mea he rongoa koiora uaua e uaua ana ki te whakahoki ano. Heoi, ka waatea pea nga putanga biosimilar a muri ake nei.

Ko etahi kamupene inihua ka hiahia pea i te whakaaetanga i mua mo Orencia na te mea he utu, engari ko te nuinga o nga tangata e mate ana i te rumatoid arthritis ka taea te kapi ina whakapumautia te hiahia rongoa.

Nga Whakakapinga Abatacept

Mena karekau te abatacept e tika ana mo koe, he maha atu nga rongoa koiora e mahi ana i nga ahuatanga autoimmune. Kei roto i enei ko te adalimumab (Humira), etanercept (Enbrel), me te rituximab (Rituxan).

Ko ngā rongoā rerekē i te mate rūmātiki (DMARDs) pērā i te methotrexate, i te sulfasalazine rānei, he mea whakamātau tuatahi, he mea whakamahi rānei i te taha o ngā rongoā koiora. He rerekē ngā tikanga mahi me ngā pānga taha o ēnei rongoā.

Ka whakaarohia e tō tākuta ngā āhuatanga pērā i tō āhua motuhake, ētahi atu raruraru hauora, ngā hiahia o te noho, me te inihua inā whiriwhiri i te rongoā pai rawa atu. I ētahi wā, ka pai ake ngā hua, ka iti ake rānei ngā pānga taha mā te whakamātau i tētahi rongoā rerekē.

He Pai Anei te Abatacept i te Methotrexate?

He rerekē te mahi a te Abatacept me te methotrexate, ā, he maha ngā wā ka whakamahia ngātahi, kaua hei rongoā whakataetae. Ko te Methotrexate te rongoā tuatahi mō te rūmātiki, ā, ka tāpirihia te abatacept i te wā e kore ai te methotrexate anake e ranea.

He rongoā tawhito, kua mōhiotia te methotrexate, ā, ka tangohia mā te pire, mā te werohanga rānei, ā, he iti ake te utu i te abatacept. Heoi, ka nui ake te pōhara o te puku, ā, me mātakitaki tonu te toto mō te mahi ate.

He pai ake pea te abatacept mō ngā tāngata e kore e kaha ki te whakamahi methotrexate, e hiahia ana rānei ki te mana whakahaere i te mumura. He maha ngā tāngata e whakamahi ana i ngā rongoā e rua ngātahi mō ngā hua pai rawa atu, i te mea e whakakī ana i ngā pānga o tētahi ki tētahi.

Ngā Pātai Auau mō te Abatacept

He Haumaru Anei te Abatacept mō ngā Tāngata e mate huka ana?

Āe, he haumaru te abatacept mō ngā tāngata e mate huka ana. Kāore te rongoā e pā tika ana ki ngā taumata huka toto, e pokanoa ana rānei ki ngā rongoā mate huka.

Heoi, ka nui ake te tūponotanga o te mate i te mate huka, ā, ka paku ake te tūponotanga o te mate i te abatacept. Ka mātakitaki tō tākuta i a koe, ā, ka tūtohu pea i ētahi atu whakatūpato pērā i te tirotiro auau i te huka toto i te wā e mate ana.

Me Pēhea Taku Mahi mēnā ka Whakamahi Au i te Abatacept Nui Rawa?

Mēnā i werohia e koe he nui ake te abatacept i te mea i tohua, whakapā atu ki tō tākuta, ki te kaimātai rongoā rānei i te wā tonu. Ahakoa he onge te nui rawa o te rongoā i ngā syringe kua whakakiia i mua, he mea nui kia whiwhi tohutohu hauora.

Kaua e ngana ki te "whakataurite" i te horopeta taapiri mā te karo i tō werohanga e whai ake nei. Ka tohutohu tō tākuta ki a koe i te huarahi haumaru ki te hoki ki te waarangi horopeta auau.

Me Pēhea Taku Mahi Mēnā Kua Ngaro i Ahau tētahi Horopeta Abatacept?

Mēnā kua ngaro i a koe tētahi werohanga i raro i te kiri, tangohia i te wā e mahara ana koe, katahi ka hoki ki tō waarangi ia wiki. Kaua e rua ngā horopeta hei utu mō te werohanga kua ngaro.

Mō ngā whakaurunga IV, whakapā atu ki te tari o tō tākuta ki te whakarite anō i te wā e taea ai. Ka whakatika pea rātou i ō pōti e whai ake nei kia hoki koe ki te waarangi pai mō tō maimoatanga.

Āhea Āhau e Kati ai te Tango Abatacept?

Me mutu anake te tango abatacept i raro i te tirotiro a tō tākuta. Ko te whakamutu ohorere ka arahi ki te mura o tō āhuatanga autoimmune i roto i ngā wiki, i ngā marama rānei.

Ka tūtohu pea tō tākuta kia mutu mēnā ka whakawhanake koe i ngā pānga taha nui, ka tutuki te murunga roa, me huri rānei ki tētahi rongoā rerekē. Ka waihanga rātou i tētahi mahere hei aroturuki i a koe i te wā o ngā okiokinga maimoatanga.

Ka Taea e Ahau te Whiwhi Kano ārai mate i te wā e Tango ana i te Abatacept?

Ko te nuinga o ngā kano ārai mate auau he haumaru i te wā e tango ana i te abatacept, engari me karo e koe ngā kano ārai mate ora pēnei i te rehu rewharewha i te ihu, i te kano ārai mate shingles rānei. Ka tūtohu tō tākuta i te werohanga rewharewha hei utu.

He mea nui kia noho whakahōuhou tonu ki ngā kano ārai mate i te wā e tango ana i te abatacept, nā te mea ka nui ake te tūponotanga o te rongoā ki ētahi mate. Whakaritea kia whiwhi i ō kano ārai mate i te wā e pai ana tō tū, ā, kāore koe e pā ana ki ngā mate kaha.