He aha te Abiraterone: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

Ko te Abiraterone he rongoā mate pukupuku e whai ana ki te aukati i te hanga testosterone. Ka mahi tēnei rongoā waha mā te aukati i tō tinana mai i te hanga homoni e whāngai ana i ētahi momo pūtau mate pukupuku prostate, e whakamate ana i te mate pukupuku i ngā mea e hiahiatia ana e ia hei tipu.

Mēnā kua tohua te abiraterone ki a koe, ki tētahi rānei e arohaina ana e koe, kei te raru pea koe i te mate pukupuku prostate kua horapa atu i tua atu i te repe prostate. Ka pōuri pea tēnei, engari mā te māramatanga ki te mahi o tēnei rongoā ka āwhina koe ki te whai wāhi atu me te māia ki tō haerenga maimoatanga.

He aha te Abiraterone?

Ko te Abiraterone he rongoā rongoā homoni i hangaia hei rongoā i te mate pukupuku prostate metastatic. Ko te tikanga o te kupu "micronized" kua tukatukahia te rongoā ki ngā matūriki iti rawa e ngāwari ana te ngongo me te whai hua o tō tinana.

No tētahi rōpū rongoā tēnei rongoā e kīia ana ko ngā aukati i te hanga androgen. Whakaarohia he taputapu tino whaihua e whai ana ki ngā ara motuhake e whakamahia ana e ngā pūtau mate pukupuku hei whāngai i tō rātou tipu. Kāore i rite ki te chemotherapy e pā ana ki te maha o ngā momo pūtau rerekē, ka arotahi te abiraterone ki ngā ara e whakaputa ana i te homoni.

Ka tae mai te rongoā hei papa waha ka tangohia e koe mā te waha, e ngāwari ana i ngā maimoatanga e hiahia ana ki ngā haerenga hōhipera mō ngā whakaurunga. Ka taea e koe te pupuri i te nuinga o tō tikanga noa i te wā e whiwhi ana koe i te maimoatanga mate pukupuku whai hua.

He aha te Abiraterone e whakamahia ana?

Ko te Abiraterone te mea nui e whakamahia ana hei rongoā i te mate pukupuku prostate metastatic castration-resistant (mCRPC). Ko te tikanga tēnei kua horapa te mate pukupuku prostate ki ētahi atu wāhi o tō tinana, ā, kei te tipu tonu ahakoa he iti rawa te taumata testosterone.

Ka tohua pea e tō tākuta te abiraterone mēnā kua piki ake tō mate pukupuku prostate ahakoa ētahi atu rongoā homoni, te tango pokanga rānei i ngā kiko e whakaputa ana i te testosterone. He maha ngā wā ka whakamahia i te wā kua horapa te mate pukupuku ki ngā wheua, ngā pona rāpoi, ētahi atu okana rānei, ā, kāore anō ngā rongoā tuku iho e whakahaere tika ana i te mate.

I ētahi wā, ka tohua hoki e ngā tākuta te abiraterone mō te mate pukupuku prostate tairongo homoni metastatic me ētahi atu rongoā. Mā tēnei huarahi e ārai te mate pukupuku kia kore e ātete ki te rongoā homoni, ā, ka taea te whakaroa i te wā i mua i te pikinga o te mate.

Me pēhea te mahi a te Abiraterone?

Ka mahi te Abiraterone mā te aukati i tētahi enzyme e kīia ana ko CYP17A1, e whakamahia ana e tō tinana ki te hanga testosterone me ētahi atu androgens. Ko ngā pūtau mate pukupuku prostate te tikanga ka whakawhirinaki ki ēnei homoni kia ora ai, kia nui ake ai, nō reira, mā te tapahi i tō rātou tuku ka taea te whakaroa, te aukati rānei i te tipu o te mate pukupuku.

E kiia ana ko tēnei rongoā he kōwhiringa rongoā kaha, whai hua hoki mō te mate pukupuku prostate kua piki ake. Ka aukati i te hanga homoni ehara i te mea i roto i ō pōro anake, engari i roto i ō repe adrenal me roto i ngā pūtau mate pukupuku anō. Mā tēnei huarahi whānui ka uaua ake ki ngā pūtau mate pukupuku te kimi i ngā homoni e hiahia ana rātou.

Te tikanga ka tīmata te mahi a te rongoā i roto i ētahi wiki, ahakoa kāore pea koe e rongo i ngā huringa tonu. Ka aroturukihia e tō tākuta ō taumata PSA (antigen motuhake prostate) me ētahi atu tohu toto hei whai i te pai o te mahi o te rongoā mōu.

Me pēhea taku tango i te Abiraterone?

Tangohia te abiraterone kia rite ki tā tō tākuta i tohutohu ai, te tikanga kotahi i te rā i runga i te puku kau. Ko te tikanga me tango e koe i te iti rawa i te hāora kotahi i mua i te kai, e rua hāora rānei i muri i te kai, nā te mea ka nui ake te rongoā e ngāwari ana te tango e tō tinana.

Horomia ngā papa katoa me te karaihe wai ki tonu. Kaua e kuru, e whati, e ngaungau rānei i ngā papa, nā te mea ka pā tēnei ki te āhua o te tuku i te rongoā ki tō tinana. Mā te tango i te rā anō ka āwhina i te pupuri i ngā taumata rite tonu o te rongoā i roto i tō pūnaha.

Me tango hoki e koe te prednisone, te prednisolone rānei me te abiraterone. Mā tēnei rongoā steroid e āwhina i te ārai i ngā pānga taha e pā ana ki ngā huringa homoni, he wāhanga nui hoki tēnei o tō mahere maimoatanga. Mā tō tākuta e whakahau te horopeta me te hōtaka tika mō ngā rongoā e rua.

Kia Pēhea te Roa e Tango Ana ahau i te Abiraterone?

Ka noho tonu koe ki te tango i te abiraterone i te wā e whakahaere ana i tō mate pukupuku, me te pai hoki o tō tinana ki te rongoā. Ka roa pea mō ngā marama, tau rānei, i runga i te āhua o te urupare a tō tinana ki te maimoatanga.

Ka aroturuki tō tākuta i tō ahunga whakamua mā ngā whakamātautau toto, ngā karapa whakaahua, me ngā whakamātautau tinana. Mēnā ka tīmata te piki o ō taumata PSA, ka whakaatu rānei ngā karapa i te piki haere o te mate pukupuku, ka whakatika pea tō tākuta i tō mahere maimoatanga, ka huri rānei ki ētahi atu rongoā.

Ko ētahi tāngata e tango ana i te abiraterone mō ngā wā roa me ngā hua pai, i te wā e hiahia ana ētahi atu ki te huri i ngā maimoatanga i mua atu. Mā tō urupare takitahi e ārahi i te roa o tō haere tonu me tēnei rongoā, ā, ka mahi tō rōpū hauora ki a koe ki te whakatau i ngā whakatau pai mō tō āhuatanga.

He Aha ngā Pānga Taha o te Abiraterone?

Pērā i ngā rongoā mate pukupuku katoa, ka taea e te abiraterone te pānga taha, ahakoa kāore katoa e pā ana ki a rātou. Ko te nuinga o ngā pānga taha ka taea te whakahaere, ā, ka aroturuki tata tō rōpū hauora i a koe ki te whakatika i ngā take ka puta.

Ko ngā pānga taha tino noa ka pā pea ki a koe ko te ngenge, te mamae tahi, te pūhi i ō waewae, ō waewae rānei, ngā uira wera, me te korere. Ko ēnei pānga ka pai ake i te wā e urutau ana tō tinana ki te rongoā, ā, he huarahi hei whakahaere i a rātou.

Ko ētahi atu pānga kino, engari he iti noa iho te auau, ko ngā raruraru ate, te pēhanga toto tiketike, ngā taumata pāhare pāporo iti, me ngā rerekētanga o te manawa. Ka tirohia ō toto e tō tākuta i ngā wā katoa kia kite wawe i ēnei take. Ka pā hoki te ngoikore o ngā uaua, te mamae wheua, rānei ngā rerekētanga o ngā taumata huka toto ki ētahi tāne.

I ngā wā onge, ka pā te kino nui o te ate, ngā raruraru ngākau, rānei te hekenga kino o te pēhanga toto i te abiraterone. Koinei te take he mea nui te aroturuki i ngā wā katoa. Ki te kite koe i te kōwhai o tō kiri, o ō kanohi, te ngenge nui, te mamae o te uma, rānei te uaua ki te hā, whakapā atu ki tō kaiwhakarato hauora tonu.

Ko wai kāore e tika kia tango Abiraterone?

Kāore te Abiraterone e tika mō te katoa, ā, ka āta arotake tō tākuta mō te tika mōu. Kāore te hunga e pā ana ki te mate ate nui e taea te tango i tēnei rongoā, nā te mea ka kino ake ngā raruraru ate.

Ki te whai hītori koe mō ngā raruraru ngākau, te pēhanga toto tiketike kāore i te whakahaerehia, rānei ētahi mate manawa, me āta whakatau tō tākuta i ngā painga ki ngā tūponotanga. Ka pā te rongoā ki tō ngākau me tō pēhanga toto, nō reira me aroturuki motuhake ēnei āhuatanga.

Kāore ngā wāhine e hapū ana, e mōhiotia ana rānei ka hapū, e tika kia whakahaere i ngā papa abiraterone, nā te mea ka pā te rongoā ki te pēpi e whanake ana. Me whakamahi ngā tāne e tango ana i te abiraterone i te whakahaere whānau whai hua ki te mea ka hapū tō rātou hoa, nā te mea ka kitea te rongoā i roto i te wai tai.

Ka whakaaro hoki tō tākuta ki ētahi atu rongoā e tango ana koe, nā te mea ka pā te abiraterone ki ngā rongoā whakaheke toto, ētahi rongoā ngākau, me ētahi atu rongoā e pā ana ki te mahi ate.

Ngā Ingoa Waitohu Abiraterone

E wātea ana te Abiraterone i raro i ētahi ingoa waitohu, ko Zytiga te waitohu taketake e mōhiotia ana. Koinei te putanga tuatahi i whakaaetia e te FDA o te abiraterone acetate, ā, e hangaia ana e Janssen Pharmaceuticals.

Kei te wātea nāianei ngā momo rongoā abiraterone mai i ngā momo kaihanga rerekē, ā, ka taea e tēnei te utu ake i te rongoā. Kei roto i ēnei momo rongoā ngā mea kaha kotahi, ā, he rite tonu te mahi ki te rongoā waitohu.

Ka whai rongoā pea tō whare rongoā i ngā momo waitohu rerekē, i ngā momo rongoā rānei, engari he rite tonu te rongoā. Mēnā he pātai āu mō te momo rongoā e whiwhi ana koe, ka taea e tō kaimahi rongoā te whakamārama i ngā rerekētanga, ā, ka āwhina i a koe kia whiwhi i te kōwhiringa e pai ana te utu.

Ngā Kōwhiringa kē atu mō te Abiraterone

Mēnā kāore te abiraterone i te tika mōu, ka mutu rānei te mahi, he maha atu ngā kōwhiringa maimoatanga e wātea ana mō te mate pukupuku pūkahukahu kua piki ake. Ko te Enzalutamide (Xtandi) tētahi atu rongoā hormone e mahi rerekē ana, engari e whai ana i ngā ara rite tonu.

He maha ngā wā ka whakamahia te rongoā matū Docetaxel mō te mate pukupuku pūkahukahu kua horapa, ko ia anake, i te taha rānei o ngā rongoā hormone. Ko ngā maimoatanga hou pēnei i te radium-223 (Xofigo) ka whai hua mēnā kua horapa te mate pukupuku ki ngā wheua, i te wā e whai wāhi ana te sipuleucel-T (Provenge) hei kōwhiringa immunotherapy.

Ka whakaaro pea tō tākuta ki ngā whakamātau haumanu o ngā maimoatanga whakamātau, ina koa kāore ngā rongoā paerewa e pai ana te mahi. Kei te haere tonu te whanaketanga o te maimoatanga mate pukupuku pūkahukahu, me ngā rongoā hou me ngā huinga e whanake ana i ia wā.

He Pai Ake Te Abiraterone I Te Enzalutamide?

He maimoatanga whai hua te abiraterone me te enzalutamide mō te mate pukupuku pūkahukahu kua piki ake, engari he rerekē te mahi. Ka aukati te abiraterone i te hanga hormone, i te wā e aukati ana te enzalutamide i te whakamahinga o ngā hormone e ngā pūtau mate pukupuku kua noho kē.

E whakaatu ana te rangahau ka taea e ngā rongoā e rua te whakaroa i te oranga me te whakapai ake i te kounga o te oranga mō ngā tāne e mate ana i te mate pukupuku pūkahukahu kua horapa. Ko te kōwhiringa i waenga i a rāua e pā ana ki tō āhuatanga motuhake, ētahi atu āhuatanga hauora, me te pēhea o tō urupare ki te maimoatanga.

He pai ake etahi tangata ki tetahi rongoa i tetahi atu, ā, ka whakaarohia e tō tākuta ngā āhuatanga pēnei i tō hauora o nāianei, ētahi atu rongoa e inu ana koe, me ngā pānga taha pea i te wā e whakatakoto ana i ngā tūtohutanga. E rua ngā rongoa tuatahi mō te mate pukupuku prostate matatau.

Ngā Pātai Auau mō Abiraterone

Q1. He Haumaru a Abiraterone mō te Hunga e Mate Pūngāwerewere ana?

Ka taea te whakamahi i te Abiraterone mō te hunga e mate pūngāwerewere ana, engari me mātakitaki me te whakahaere. Ka pā te rongoa ki te pēhanga toto me te manawataki, nō reira me mahi tahi tō kaimātai pūngāwerewere me te tohunga mate pukupuku kia noho haumaru koe.

Tērā pea ka mātakitakihia e tō tākuta tō ngākau, ka tirohia tō pēhanga toto i ngā wā katoa, ā, ka whakatikatikahia ētahi atu rongoa ngākau e inu ana koe. He maha ngā tāngata e mate pūngāwerewere ana ka whai hua tonu mai i te rongoa abiraterone ina tika te tirotiro.

Q2. Me Pēhea Taku Mahi ki te Inu Auau i te Nui rawa o Abiraterone?

Mēnā ka inu auau koe i te nui rawa o te abiraterone i te mea i whakaritea, whakapā atu ki tō tākuta, ki te pokapū whakahaere paitini tonu. Ko te inu i te nui rawa ka piki ake te tūponotanga o ngā pānga taha nui, ina koa ngā raruraru ate me ngā huringa manawataki.

Kaua e tatari kia kite mēnā kei te pai koe. Ahakoa kāore koe e kite i ngā tohu tonu, ka taea e te nui rawa te pānga i muri mai e hiahia ana ki te āwhina hauora. Ka taea e tō rōpū hauora te tohutohu i a koe mō te mea hei mātakitaki me te mea e hiahia ana koe ki te āwhina hauora tonu.

Q3. Me Pēhea Taku Mahi ki te Whakaheke i te Inenga o Abiraterone?

Mēnā ka whakaheke koe i te inenga o te abiraterone, tangohia i te wā e mahara ana koe, engari mēnā he iti iho i te 12 hāora mai i tō wā inenga kua whakaritea. Mēnā kua roa ake i te 12 hāora, waiho te inenga i whakahekea, ka tango i tō inenga e whai ake nei i te wā tika.

Kaua rawa e tango e rua nga horopeta i te wa kotahi hei utu mo te horopeta i ngaro, na te mea ka piki ake te tupono o nga paanga taha. Mēnā he maha ngā wā e wareware ana koe ki ngā horopeta, whakaarohia te whakatakoto i ngā whakamaharatanga waea, te whakamahi rānei i tētahi kaiwhakarite pire hei āwhina i a koe kia noho i runga i te ara.

Q4. Āhea Ānei Ka Taea e Au te Kati te Tango Abiraterone?

Me mutu noa koe te tango abiraterone ina tohutohu tō tākuta ki a koe. Ko te tikanga ka puta tēnei mena ka piki ake te mate pukupuku ahakoa te rongoā, mena ka whanake koe i ngā pānga taha nui, mena rānei ka tūtohu tō tākuta kia huri ki tētahi atu huarahi rongoā.

Kaua rawa e mutu te tango abiraterone ohorere ana, me te kore e tirotirohia e te tākuta, nā te mea ka taea e tēnei te tuku i tō mate pukupuku kia tere ake te piki. Ka aroturuki tō tākuta i tō āhua i ngā wā katoa, ā, ka kōrero ki a koe mō ngā huringa ki tō mahere rongoā.

Q5. Ka Taea e Au te Inu Waipiro i te Wā e Tango ana i te Abiraterone?

He pai ake te whakaiti i te inu waipiro i te wā e tango ana i te abiraterone, nā te mea ka pā te waipiro me te rongoā ki tō ate. He pai te inu i te wā kotahi, i te āhua ngawari, engari me kōrero koe i tēnei ki tō tākuta i runga i tō āhuatanga takitahi.

Mēnā he raruraru tō ate, e tango ana rānei koe i ētahi atu rongoā e pā ana ki te ate, ka tūtohu pea tō tākuta kia karo katoa i te waipiro. Ka taea e tō rōpū hauora te whakarato i ngā aratohu whaiaro i runga i tō hauora whānui me te mahere rongoā.