He aha te Alpha-1-Proteinase Inhibitor: Ngā Whakamahinga, te Inenga, Ngā Pānga taha me ētahi atu

Ko te Alpha-1-proteinase inhibitor he rongoā whakakapi pūmua e tukuna ana mā te IV hei āwhina i te hunga e mate ana i tētahi āhua ira onge e kīia ana ko te alpha-1 antitrypsin deficiency. E mahi ana tēnei rongoā mā te whakakapi i tētahi pūmua ngaro, he pūmua hē rānei, e tiaki ana i ō pūkahukahu i te kino.

Mēnā kua tātai koe, tētahi rānei e manaaki ana koe, i te alpha-1 antitrypsin deficiency, tērā pea ka pōuri koe i ngā mōhiohio rongoā katoa. Me haere tātou i ngā mea e pā ana ki tēnei rongoā me te pēhea e āwhina ai i te tiaki i tō hauora pūkahukahu i te roanga o te wā.

He aha te Alpha-1-Proteinase Inhibitor?

Ko te Alpha-1-proteinase inhibitor he rongoā pūmua i tātāia, i hangaia mai i te plasma toto tangata i tūao. Kei roto i a ia te pūmua tiaki kotahi e hangaia ana e te hunga hauora i roto i ō rātou ate, e kīia ana ko te alpha-1 antitrypsin.

Ko te hunga e mate ana i te alpha-1 antitrypsin deficiency kāore e hanga ana i te nui o tēnei pūmua, e hanga ana rānei i tētahi putanga hē e kore e pai te mahi. Ki te kore e nui te pūmua e mahi ana, ka taea e ngā enzyme i roto i ō pūkahukahu te kino i ngā pūkahukahu i te roanga o te wā, e arahi ana ki ngā raruraru manawa.

E mahi ana tēnei rongoā hei whakangungu rakau mō ō pūkahukahu. Ki te tukuna i ngā wā katoa mā te IV, ka āwhina i te whakahoki i ngā taumata pūmua tiaki i roto i tō toto me ō pūkahukahu, e whakaroa ana i te haere o te kino o te pūkahukahu.

He aha te Alpha-1-Proteinase Inhibitor e whakamahia ana mō?

I hangaia tēnei rongoā hei rongoā i te alpha-1 antitrypsin deficiency, tētahi āhua ira e pā ana ki te 1 i roto i te 2,500 tāngata. E whakamahia ana i te wā e whakaatu ana ngā whakamātautau toto he iti rawa ō taumata o te pūmua alpha-1 antitrypsin.

Ko te whāinga matua he whakaroa i te kino o te pūkahukahu me te tiaki i tō mahi manawa. Ahakoa e kore e taea e ia te whakahoki i te kino kua pā kē, ka taea e ia te āwhina i te aukati, i te whakaroa rānei i te kino atu o tō kiko pūkahukahu.

Ka tohutohu tō tākuta i tēnei rongoā ki a koe mēnā he ngoikoretanga ira tōu me ngā tohu o te mate pūkahukahu, pēnei i te emphysema, te mate pūkahukahu aukati mau tonu (COPD) rānei. Kāore i te whakamahia mō ētahi atu momo raruraru pūkahukahu kāore i te pā ki te ngoikoretanga alpha-1 antitrypsin.

Me pēhea te mahi a te Alpha-1-Proteinase Inhibitor?

E mahi ana tēnei rongoā mā te whakakapi i te pūmua whakamarumaru ngaro i tō tinana. Whakaarohia te alpha-1 antitrypsin hei kaitiaki mō ō pūkahukahu - ko te tikanga e ārai ana i ngā whākōrere kino mai i te whakaeke i te kiko pūkahukahu hauora.

I te wā e whiwhi ana koe i te whakaurunga IV, ka haere te rongoā mā roto i ō toto, ka tae ki ō pūkahukahu. I reira, ka herea, ka whakakore i ngā whākōrere e kīia ana ko te neutrophil elastase, ka taea te wawahi i ngā pakitara o ō pūkahukahu mēnā kāore i te tirotirohia.

E kiia ana he rongoā kaha-waenga e hiahia ana kia whakamahia tonu. Kāore te rongoā e rongoā i te āhuatanga ira e takoto ana, engari e whakarato ana i te whakamarumaru pumau i te wā e hoatu ana i ngā wā katoa. E hiahia ana te nuinga o te tangata ki ngā whakaurunga ia wiki kia mau tonu ngā taumata pūmua whakamarumaru i roto i tō rātou pūnaha.

Me pēhea taku tango i te Alpha-1-Proteinase Inhibitor?

Ka hoatu tonu tēnei rongoā hei whakaurunga i roto i te uaua (IV) i roto i te taiao hauora. Ko te tikanga ka whiwhi koe i te rongoā kotahi i te wiki, ā, ka roa te whakaurunga kotahi i te 15 ki te 30 meneti hei whakaoti.

I mua i tō whakaurunga, kāore koe e hiahia ki te karo i te kai, i te inu rānei. Inaha, mā te kai i te kai māmā i mua ka āwhina i a koe kia pai ake te ngākau i te wā o te rongoā. Me mōhio ki te noho pai te wai mā te inu nui i te wai i te roanga o te rā.

Ka hoatu te whakaurunga i te pōturi kia iti ai ngā urupare. Ka āta aroturukihia koe e tō rōpū hauora i te wā o te rongoā me muri iho. E kitea ana e ētahi tangata he āwhina ki te kawe mai i te pukapuka, i te papa rānei kia noho pukumahi i te wā o te whakaurunga.

Kia pehea te roa e tango ai au i te Alpha-1-Proteinase Inhibitor?

Ko te aukati i te alpha-1-proteinase he rongoā mō te roanga o te ora. I te mea he āhua ira te ngoikoretanga o te alpha-1 antitrypsin, ka uaua tonu tō tinana ki te whakaputa i te nui o tēnei pūmua whakamarumaru i a ia anō.

Ko te whāinga kia mau tonu te whakamarumaru mō ō pūkahukahu i ngā tau maha. Mā te whakamutu i te rongoā ka taea e ngā whākōkī kino te hoki ki te whakangaro i ō kiko pūkahukahu, ka hua pea te tere o te haere o te emphysema, ētahi atu raruraru pūkahukahu rānei.

Ka aroturuki tō tākuta i te mahi o ō pūkahukahu me ngā taumata pūmua mā ngā whakamātautau toto me ngā whakamātautau manawa. Mā ēnei e āwhina ki te whakatau mēnā kei te pai te mahi o te rongoā, mehemea e tika ana kia whakatikatikaina tō mahere atawhai.

He aha ngā pānga taha o te aukati i te Alpha-1-Proteinase?

He pai te whakamanawanui o te nuinga o te tāngata ki tēnei rongoā, engari pērā i ētahi atu rongoā, ka pānga taha. Mā te māramatanga ki ngā mea e tūmanakohia ana ka āwhina koe ki te noho rite, me te mōhio ki te wā ki te whakapā atu ki tō rōpū hauora.

Ngā pānga taha noa e pā ana ki te neke atu i te 1 i roto i te 10 tāngata ko ngā tauhohenga ngawari i te wāhi werohanga, pērā i te mamae iti, te whero, te pūhihi rānei i te wāhi i tū ai te ngira IV. Ka pā pea te ānini ngawari, te whanoke, te ngenge rānei i muri i tō werohanga.

• Ngā tauhohenga wāhi werohanga (mamae, whero, pūhihi)
• Ānini
• Whanoke, te māmā rānei o te upoko
• Ngenge, te ngenge rānei
• Te whakapairuaki, te pōpōrangi puku ngawari rānei
• Ngā mamae uaua

Ko ēnei pānga taha noa te tikanga ka pai ake i roto i ngā hāora ruarua i muri i te rongoā, ā, he uaua te hiahia kia whakamutua te rongoā.

Ngā pānga taha kāore i te noa engari he nui ake te kino ka pā ki te 1 i roto i te 100 tāngata. Kei roto i ēnei ko ngā tauhohenga pāwera, ka puta pea hei pānga kiri, te mōmona, te uaua ki te manawa, te pūhihi rānei o tō mata, ngā ngutu, te korokoro rānei.

• Ngā tauhohenga pāwera (pāpā, mōmona, raruraru manawa)
• Mamae o te uma, te pōro rānei
• Te tere o te ngākau
• He nui te mamae o te upoko
• Kirika nui, te wiri rānei
• Te nui o te whakapairuaki, te ruaki rānei

Mēnā ka pā ki a koe ētahi o ēnei tohumate nui ake, whakamōhio tonu ki tō rōpū hauora. Ka taea e rātou te whakatika i tō rongoā, te whakarato rānei i ētahi atu tautoko hei āwhina i te whakahaere i ēnei pānga.

I ngā wā onge, ka tupu pea te toto i ētahi tāngata, ka pā rānei te tauhohenga pāwera nui e kīia ana ko te anaphylaxis. E iti iho i te 1 i roto i te 1,000 ngā tāngata ka pā ēnei raruraru nui, engari ka rite tonu tō rōpū hauora ki te whakahaere i a rātou mēnā ka pā.

Ko wai e kore e tango i te Alpha-1-Proteinase Inhibitor?

Kāore tēnei rongoā i te pai mō te katoa. Ka āta arotake tō tākuta i tō hītori hauora kia mōhio ai he haumaru ki a koe te whiwhi i tēnei rongoā.

Kaua koe e whiwhi i te alpha-1-proteinase inhibitor mēnā i pā ki a koe te tauhohenga pāwera nui ki tēnei rongoā, ki ētahi o ōna kai rānei i mua. Ko ngā tāngata e pā ana ki ētahi mate toto, ki te hunga rānei e tango ana i ngā rongoā whakaheke toto motuhake, ka hiahia pea ki ētahi atu rongoā.

Ka hiahia tō tākuta ki te mōhio mō ngā hītori o te toto, ngā raruraru o te ngākau, te mate tākihi rānei. Ahakoa kāore ēnei āhuatanga e aukati aunoa i te rongoā, ka hiahia pea rātou ki te aroturuki atu, ki te whakatika rānei i te horopeta kia noho haumaru ai koe.

Mēnā kei te hapū koe, kei te whāngai ū rānei, me kōrero tēnei ki tō rōpū hauora. Ahakoa he iti noa te rangahau mō te haumaru i te wā e hapū ana, ka taea e tō tākuta te āwhina i te whakatau i ngā painga me ngā tūponotanga mō tō āhuatanga motuhake.

Ngā Ingoa Waitohu Alpha-1-Proteinase Inhibitor

He maha ngā kamupene rongoā e hanga ana i ngā rongoā alpha-1-proteinase inhibitor, ā, e wātea ana i raro i ngā ingoa waitohu rerekē. Ko ngā putanga e tino tohua ana ko Prolastin-C, Glassia, me Zemaira.

Ahakoa kei roto i enei hua te whakauru kaha kotahi, he iti nei pea te rerekē o te tukatuka, te whakakaha rānei. Mā tō tākuta e whiriwhiri te kōwhiringa e tika ana i runga i ō hiahia me tō hītori hauora.

He rite tonu te mahi o ēnei rongoā katoa, ā, he rite tonu te whai hua. Ki te hiahia koe ki te huri i waenga i ngā waitohu mō tētahi take, mā tō rōpū hauora koe e ārahi i te huringa kia noho haumaru.

Ngā Kōwhiringa kē atu mō te Alpha-1-Proteinase Inhibitor

I tēnei wā, ko te alpha-1-proteinase inhibitor IV te rongoā tuatahi mō te ngoikoretanga o te alpha-1 antitrypsin. Heoi, kei te mahi ngā kairangahau ki te whakawhanake i ngā tikanga tuku kē atu ka pai ake pea i te wā anamata.

Kei te rangahaua tētahi momo rongoā e ngāhia ana i roto i ngā whakamātau haumanu. Mā tēnei pea koe e āhei ai ki te tango i te rongoā i te kāinga, kaua ki te haere ki tētahi whare hauora i ia wiki. Heoi, kāore anō tēnei kōwhiringa i te wātea mō te whakamahi i ia rā.

Mō ētahi tāngata, ko ngā rongoā tautoko pēnei i te bronchodilators, te rongoā hāora, te whakahounga pūkahukahu rānei, ka taea te whakakī i te rongoā alpha-1-proteinase inhibitor. Kāore ēnei e whakakapi i te hiahia mō te whakakapinga pūmua engari ka taea te āwhina ki te whakahaere i ngā tohumate me te whakapai ake i te kounga o te oranga.

He Pai Anei te Alpha-1-Proteinase Inhibitor i Ētahi Atu Rongoā?

I tēnei wā, ko te alpha-1-proteinase inhibitor anake te rongoā e whakatika ana i te ngoikoretanga pūmua i roto i te ngoikoretanga o te alpha-1 antitrypsin. Ka taea e ētahi atu rongoā te āwhina ki te whakahaere i ngā tohumate engari kāore e whakarato i ngā painga whakamarumaru kotahi mō ō pūkahukahu.

Ki te whakataurite ki te whakamahi noa i te bronchodilators, ētahi atu rongoā COPD rānei anake, kua whakaaturia te rongoā whakakapinga pūmua ki te whakaroa i te haere whakamua o te kino o te pūkahukahu. E ai ki ngā rangahau ka taea e ia te āwhina ki te tiaki i te mahi pūkahukahu i te roanga o te wā, ina koa ka tīmata i mua i te puta o te kino nui.

Ko te painga nui ko te whai i te take o te raru, kaua ki te rongoa noa i nga tohu. Ahakoa he mea nui etahi atu rongoa mo te whakahaere i nga raruraru manawa i ia ra, ka tukuna e te aukati alpha-1-proteinase he whakamarumaru mo te wa roa e kore e taea e etahi atu whiringa.

Nga Patai e Pā ana ki te Aukati Alpha-1-Proteinase

He Haumaru te Aukati Alpha-1-Proteinase mo te Hunga e mate ana i te Ngakau?

Ka taea te whakamahi i te aukati alpha-1-proteinase i roto i te hunga e mate ana i te ngakau, engari he mea nui te aroturuki atu. Ka tukuna te rongoa i te wa roa hei whakaiti i te tupono o te nui o te wai, te taumahatanga ranei o te ngakau.

Ka ata titiro to taakuta ki to ahuatanga ngakau i mua i te tiimata i te rongoa. Ka taea e ratou te whakatika i te reiti whakauru, te aroturuki ranei i a koe i te wa o nga rongoa kia mohio ai ka pai te whakahaere a to ngakau i te wai taapiri.

Me aha ahau ki te whiwhi au i te nui rawa o te Aukati Alpha-1-Proteinase?

I te mea ka tukuna tenei rongoa e nga tohunga hauora i roto i nga waahi whakahaere, he tino onge te nui o te rongoa. Ka ata tatau te inenga i runga i to taumaha, ka aroturukihia puta noa i te tukanga whakauru.

Mena kei te awangawanga koe mo to inenga, kei te pa ranei koe i nga tohu rereke i te wa, i muri ranei i te rongoa, korero tonu ki to roopu hauora. Ka taea e ratou te arotake mena e tika ana etahi atu aroturuki, rongoa ranei.

Me aha ahau ki te ngaro au i te inenga o te Aukati Alpha-1-Proteinase?

Mena ka ngaro koe i to whakaurunga ia wiki, whakapā atu ki to kaiwhakarato hauora i te wa e taea ai ki te whakarite ano. He mea nui ki te pupuri i nga taumata pūmua i roto i to punaha mo te tiaki pai i te pūkahukahu.

Kaua e neke atu i te 7-10 ra i waenga i nga rongoa mena ka taea. Ka taea e to roopu hauora te awhina i a koe ki te hoki ki te ara me to waarangi auau, a ka aroturukihia pea e ratou o taumata pūmua i muri i te inenga kua ngaro.

Ahea ka taea e au te whakamutu i te tango i te Aukati Alpha-1-Proteinase?

Kei te nuinga o te wā ka haere tonu te aukati i te alpha-1-proteinase mō te wā roa e ora ana koe, e tika ana kia whiwhi koe, ā, e whai hua ana. Kāore te āhua ira e ngaro, nō reira he mea tika te tiaki tonu.

Ka arotakehia e tō tākuta i ngā wā katoa mēnā e tika ana tonu te rongoā mōu. Ko ngā āhuatanga pēnei i te hauora whānui, te mahi o te pūkahukahu, me te kounga o te oranga, he mea nui katoa ki te whakatau mēnā ka haere tonu te rongoā.

Ka taea e au te haere i te wā e tango ana i te aukati i te Alpha-1-Proteinase?

Āe, ka taea e koe te haere i te wā e whiwhi ana koe i tēnei rongoā, engari me whakamahere. Me mahi tahi koe me ngā whare hauora i tō ūnga ki te whakarite i ngā whakaurunga, ki te whakatika rānei i tō hōtaka haerenga i ngā rā rongoā.

He maha ngā pokapū rongoā ka āwhina i te mahi tahi i te tiaki me ngā whare i ētahi atu tāone. He pai ki te tīmata i te whakamahere i ngā wiki i mua i tō haerenga kia mau tonu te tiaki i a koe e ngaro ana.