He aha te waikawa Aminolevulinic (Ara-a-waha): Ngā Whakamahinga, Inenga, Ngā Pānga Taha me ētahi atu mea

Ko te waikawa Aminolevulinic (ALA) he matū tūturu e hangaia ana e tō tinana hei wāhanga o te hanga i ngā pūtau toto whero. Ina tangohia hei rongoā, ka mahi hei ākena whakaahua, ko te tikanga ka nui ake te tairongo o ētahi pūtau ki te mārama. Mā tēnei āhuatanga motuhake ka taea e ngā tākuta te whakamahi i roto i te rongoā motuhake e kiia nei ko te rongoā whakaahua, ko te nuinga mō ētahi momo āhua kiri me te mate pukupuku.

He aha te waikawa Aminolevulinic?

Ko te waikawa Aminolevulinic he pūhui e hangaia ana e tō tinana i roto i ngā rahinga iti ia rā. Kei roto i te rongoā-a-waha tētahi putanga waihanga o tēnei matū kotahi, i hangaia hei kohikohi i roto i ngā pūtau kōaro puta noa i tō tinana. Whakaarohia he kaiawhina whāinga e tohu ana i ngā wāhi raruraru mō te rongoā.

Ka mahi te rongoā mā te uru mai i te nuinga o ngā pūtau e tere ana te tipu, e kōaro ana rānei, pēnei i ngā pūtau mate pukupuku, i ngā kiko i mua i te mate pukupuku rānei. Kia uru mai ai ēnei pūtau i te waikawa aminolevulinic, ka tino tairongo rātou ki ngā ngaru mārama motuhake, ka taea te whakamahi i te rongoā hei whakangaro i a rātou.

He aha te waikawa Aminolevulinic e whakamahia ana mō?

Ko te whakamahinga tuatahi o te waikawa aminolevulinic-a-waha kei roto i te rongoā whakaahua mō ētahi āhua hauora. Ka tohutohu pea tō tākuta i tēnei hei āwhina i te tātaritanga, i te rongoā rānei i ētahi momo tipu kiko kōaro, ina koa ki ngā wāhi uaua ki te tae atu ki ngā rongoā kaupapa.

Ko ngā whakamahinga noa ko te rongoā i ētahi āhua pūpū, ina koa ko te mate pukupuku pūpū kore-uaua me te carcinoma in situ. Ka whakamahi hoki ētahi tākuta i tēnei mō te kite i ngā kiko kōaro i roto i te pūpū i ngā wā o ngā mahi pokanga, i te mea ka whiti ngā wāhi i rongoāhia i raro i te mārama kikorangi motuhake, ka māmā ake te tautuhi me te tango.

I ētahi wā, ka tūtohu pea tō tākuta hauora i te waikawa aminolevulinic mō ngā whakamahinga kore-tapanga, pērā i te rongoā i ētahi āhuatanga kiri, i ētahi atu momo mate pukupuku pāpaku rānei. Heoi anō, he iti noa iho ēnei whakamahinga, me te whakaaro nui ki ngā painga me ngā tūponotanga.

Me pēhea te mahi a te Waikawa Aminolevulinic?

E kiia ana he rongoā kaha-āhua te waikawa aminolevulinic e mahi ana mā tētahi tukanga koiora whakamīharo. Ka tangohia e koe mā te waha, ka haere mā roto i ō toto, ka uru ki roto i ngā pūtau puta noa i tō tinana, me te nui ake o te uru o ngā pūtau kōaro i ngā pūtau hauora.

I roto i ēnei pūtau whāinga, ka huri te waikawa aminolevulinic ki tētahi matū e kīia ana ko te protoporphyrin IX, e mahi ana pērā i te antenna māori mō te mārama. I te wā e whakaatu ana tō tākuta i te wāhi i rongoāhia ki ngā ngaru mārama kikorangi, whero rānei, ka mimiti te protoporphyrin IX i tēnei pūngao, ka waihanga i ngā momo hāora urupare e whakangaro ana i ngā pūtau kōaro.

He tino kōwhiri tēnei tukanga, ko te tikanga ka pā te pānga ki ngā pūtau raruraru, me te waiho i ngā kiko hauora kāore i pā. Ko te katoa o te tukanga e hia hāora te roa mai i te wā e tango ana koe i te rongoā tae noa ki te tīmatanga o te rongoā mā te mārama, e āhei ai te kohikohi pai i roto i ngā pūtau whāinga.

Me pēhea taku tango i te Waikawa Aminolevulinic?

Me tango e koe te waikawa aminolevulinic i te mea tonu i whakaritea e tō tākuta, te nuinga he horopeta kotahi mā te waha i konatunatua ki te wai. Ko te rongoā te nuinga ka tae mai i te pūao e hiahia ana kia whakarewahia ki te nui o te wai i mua i te inu, ā, ka whakarite tō rōpū hauora i tēnei ranunga mōu.

Ko te tango i te rongoā i runga i te puku kau e tūtohutia ana, nā te mea ka raru te kai i tōna urunga. Ka tono pea tō tākuta kia kaua koe e kai mō te 2-3 hāora i mua i te tango i te horopeta. Ka taea e koe te hoki ki te kai i te 4-6 hāora i muri i te tango i te rongoā, ki te kore tō tākuta e hoatu ētahi atu tohutohu.

He mea nui te wā e tango ana koe i te waikawa aminolevulinic, nā te mea me whai wā ki te kohikohi i roto i ngā pūtau e whāia ana i mua i te tīmatanga o te rongoā mā te mārama. Ko te nuinga o ngā tikanga e hiahia ana kia tango koe i te rongoā i te 1-3 haora i mua i tō wāhanga rongoā photodynamic, i runga i te āhua motuhake e rongoāhia ana.

Kia Pēhea te Roa e Tango Ana ahau i te Waikawa Aminolevulinic?

Ko te waikawa Aminolevulinic te tikanga ka hoatu hei horopeta kotahi, kaua hei rongoā wā-roa. Ko te nuinga o ngā tikanga rongoā e whai ana ki te tango i tētahi horopeta i mua i ia wāhanga rongoā photodynamic, ā, tērā pea ka hiahia koe ki ngā wāhanga maha e whakatakotoria ana i ngā wiki, i ngā marama rānei.

Ko te maha o ngā rongoā e hiahia ana koe ka whakawhirinaki ki tō āhua motuhake me te pai o tō urupare ki te rongoā. Ko ētahi tāngata ka kite i te whakapai ake nui i muri i te wāhanga kotahi noa iho, engari ko ētahi atu ka hiahia pea ki te 2-4 rongoā kia tutuki ai ngā hua e hiahiatia ana. Ka aroturukihia e tō tākuta tō ahunga whakamua me te whakatau i te hōtaka rongoā pai rawa atu mō tō āhuatanga.

I waenga i ngā rongoā, e kore koe e tango i te waikawa aminolevulinic i ia rā. Engari, ka tango koe i te rā e whakaritea ana mō te rongoā photodynamic, e tino rerekē ana i te nuinga o ētahi atu rongoā e mōhio ana koe.

He Aha ngā Pānga taha o te Waikawa Aminolevulinic?

Pērā i ngā rongoā katoa, ka taea e te waikawa aminolevulinic te pānga taha, ahakoa he maha ngā tāngata e pai ana ki te tango. Ko te māramatanga ki ngā mea e tūmanakohia ana ka āwhina i a koe kia pai ake te whakarite me te mōhio ki te wā ki te whakapā atu ki tō rōpū hauora.

Ko ngā pānga taha noa e pā ana ki a koe ko te whakapairuaki, te ruaki, me te kore mārie o te puku, ina koa i ngā haora i muri i tō horopeta. Ko ēnei tohumate keri kai te tikanga ka ngaro noa iho i roto i te 24-48 haora, ā, ka taea te whakahaere ki ngā rongoā anti-nausea ki te hiahiatia.

Anei ngā pānga taha e pūrongohia ana e ngā tāngata:

• Te whakapairuaki me te ruaki (e pā ana ki te 10-30% o ngā tūroro)
• Te mamae o te puku, te kōpū rānei
• Te pāhau, te tūtae rānei he ngohengohe
• Te ngenge, te kore rānei e pai te tū
• Te ānini
• Te whanoke, te māmā rānei te mahunga

Ko ēnei pānga taha noa he ngawari ki te āhua, he wā poto noa iho. Ko te nuinga o te tangata e kite ana mā te noho wai me te okioki ka āwhina i te whakahaere i ēnei tohumate.

Ko ngā pānga taha nui ake he mea iti noa iho, engari me whai wāhi tonu te rongoā. Me whakapā atu koe ki tō tākuta i te wā tonu ki te pā mai ngā pānga mate pāwera nui, tae atu ki te uaua ki te hā, te pūhi o tō mata, o tō korokoro rānei, te pāhau rānei e horapa ana. Hei tāpiri, ko te ruaki nui, te ruaki tonu rānei e kore ai koe e pupuri wai, me whai wāhi tonu te arotake rongoā.

Ko ētahi pānga taha onge, engari he mea nui, ko ngā huringa o te mahi ate, koinei te take ka āta titiro tō tākuta ki ō enzyme ate mā ngā whakamātautau toto. He mea onge rawa, ka pā mai pea ngā pānga ngākau nui ake, ngā pānga kiri nui rānei, ina koa ki te pā mai te mārama kanapa i muri tata i te rongoā.

Ko wai kāore e tika kia tango i te waikawa Aminolevulinic?

Kāore ētahi tāngata e tika kia tango i te waikawa aminolevulinic nā te piki o te tūponotanga o ngā raruraru, te iti rānei o te whai huatanga. Ka āta arotake tō tākuta i tō hītori rongoā kia whakatau mēnā he haumaru tēnei rongoā mōu.

Kāore koe e tika kia tango i te waikawa aminolevulinic mēnā e mōhiotia ana he mate pāwera tōu ki te rongoā, ki ētahi o ōna wāhanga rānei. Hei tāpiri, ko ngā tāngata e pā ana ki ētahi mate toto, ina koa ko te porphyria (he rōpū o ngā mate onge e pā ana ki te matū toto), me karo tēnei rongoā nā te mea ka kino ake tō rātou āhua.

He maha ētahi atu āhua ka kore ai te waikawa aminolevulinic e tika mōu:

• Te mate pūkahukahu nui, te kore rānei o te pūkahukahu
• Te mate ate nui, te kore rānei o te ate
• Te hapū, te whāngai u rānei
• Te toto nui i roto i te puku
• Ngā mate ngākau nui, te whakaeke ngākau tata rānei
• Ētahi mate ārai-tinana e pā ana ki te tairongo ki te mārama

Ka whakaaro hoki tō tākuta ki ō rongoā o nāianei, nā te mea ka pāhekoheko ētahi rongoā ki te waikawa aminolevulinic, ka pā rānei ki te āhua e tukatukahia ai e tō tinana. Mā tēnei aromatawai tōtika e whakarite kia haumaru, kia whai hua hoki te rongoā mō tō āhuatanga motuhake.

Ngā Ingoa Waitohu o te Waikawa Aminolevulinic

E wātea ana te waikawa aminolevulinic i raro i ētahi ingoa waitohu, i runga i te hanganga me te whakamahinga. Ko te momo waha e tino whakahauhia ana e mōhiotia ana ko Gleolan i roto i te maha o ngā whenua, ahakoa he rerekē te wātea i ia rohe.

I te United States, ka wātea pea te hanganga waha i raro i ētahi ingoa waitohu rerekē, i te rongoā rānei, i runga i te tohu me te kaihanga. Mā tō whare rongoā e whakarato ki a koe te waitohu tika i whakahauhia e tō tākuta.

He mea tika kia mōhio he momo ā-roto (e whakamahia ana ki te kiri) o te waikawa aminolevulinic e wātea ana i raro i ētahi ingoa waitohu rerekē, pērā i te Levulan Kerastick. Heoi anō, he hanganga rerekē rawa ēnei, kaua e whakawhitiwhiti ki te rongoā waha.

Ngā Kōwhiringa kē mō te Waikawa Aminolevulinic

Mēnā kāore te waikawa aminolevulinic e tika ana mōu, ka whakaaro pea tō tākuta ki ētahi atu rongoā i runga i tō āhuatanga motuhake. Mō te mate pukupuku pūpū, ko ētahi atu kōwhiringa pea ko ētahi atu āpiha whakaahua, ētahi atu rānei huarahi rongoā rerekē.

Ko ētahi atu rongoā whakaahua-whakaoho ko te methyl aminolevulinate (MAL) me ētahi atu pūhui i runga i te porphyrin, ahakoa e whakamahia ana ēnei mō ngā āhuatanga rerekē, ngā tikanga tuku rānei. Ka whakaaro pea tō tākuta ki ngā rongoā tuku iho pēnei i te chemotherapy, te immunotherapy, ngā kōwhiringa pokanga rānei.

Ko te kōwhiringa o te rongoā kē e tino whakawhirinaki ana ki tō tātaritanga motuhake, te hauora whānui, me ngā whāinga rongoā. Ka mahi tahi tō rōpū hauora ki a koe ki te kimi i te kōwhiringa tino tika mēnā kāore te waikawa aminolevulinic te kōwhiringa tika mō tō āhuatanga.

He Pai Anei te Waikawa Aminolevulinic i Ētahi Atu Whakaahua-whakaoho?

He maha ngā painga o te waikawa aminolevulinic i ngā rongoā whakaahua-whakaoho kē, ina koa ki te tere o te whakawātea i tō pūnaha. Kāore i rite ki ētahi atu whakaahua-whakaoho ka tairongo koe ki te mārama mō ngā wiki, ko te waikawa aminolevulinic te tikanga ka tairongo koe ki te mārama mō te 24-48 haora anake.

Ko tēnei wā poto o te tairongo ki te mārama ka pai ake mō ngā tūroro, ka whakaiti i te tūponotanga o ngā raruraru o te whakaaturanga mārama tūpono. I tua atu, ka puta noa te waikawa aminolevulinic i tō tinana, ka whakaiti pea i te tūponotanga o ētahi momo tauhohenga pāwera i te whakataurite ki ngā rongoā kēhanga katoa.

Heoi, ko te kōwhiringa

Ka taea te whakamahi i te waikawa Aminolevulinic i roto i te hunga mate huka, engari me tino aro turuki koe e tō tākuta. Kāore te rongoā nei e pā tika ana ki ngā taumata huka toto, engari ko te pēhanga o te rongoā me ngā pānga taha pea pēnei i te whakapairuaki, te ruaki rānei, ka pā ki tō mana whakahaere huka toto.

Mēnā he mate huka tō, me mōhio tō rōpū hauora kia taea e rātou te whakatika i tō aroturuki me te whakatika pea i ō rongoā mate huka i te wā o te rongoā. Me whakamahere hoki koe ki te tirotiro i tō huka toto i ngā rā rongoā.

Me pēhea te mahi mēnā ka whakamahi au i te waikawa Aminolevulinic nui rawa atu?

Mēnā ka tango koe i te waikawa aminolevulinic nui atu i te mea i whakaritea, whakapā atu ki tō tākuta, ki ngā ratonga ohorere rānei tonu. Ka taea e te horopeta nui te whakanui i te tūponotanga o ngā pānga taha kino, ina koa ko te piki o te tairongo ki te marama me te whakapairuaki, te ruaki rānei.

Kaua e ngana ki te whakaoho i te ruaki ki te kore koe i tohutohutia e ngā tākuta. Engari, rapua he āwhina hauora tonu i reira ka taea e ngā kaiwhakarato hauora te aroturuki i a koe mō ngā raruraru me te whakarato i te manaaki tautoko e tika ana mēnā e hiahiatia ana.

Me pēhea te mahi mēnā ka ngaro au i te horopeta o te waikawa Aminolevulinic?

I te mea ka hoatu te waikawa aminolevulinic hei horopeta kotahi i mua i te rongoā photodynamic, ko te ngaro i te horopeta te tikanga me whakarite anō tō rongoā katoa. Whakapā atu ki tō rōpū hauora tonu mēnā ka ngaro i a koe tō horopeta kua whakaritea.

Me whakarite anō e tō tākuta te rongoā me te rongoā mā te marama, i te mea he mea nui te wā i waenga i ēnei mea e rua mō te whai hua. Kaua e ngana ki te tango i te rongoā i a koe anō, ki te whakatika rānei i te wā me te kore e tirotirohia e te tākuta.

Āhea ka mutu ai taku tango i te waikawa Aminolevulinic?

Kāore koe e "mutu" te tango waikawa aminolevulinic i te tikanga tuku iho, nā te mea ka hoatu i ngā horopeta takitahi, kaua i te rongoā tonu. Ka oti tō akoranga rongoā i te wā e oti ana i a koe ngā wāhanga rongoā photodynamic katoa i whakaritea e tō tākuta.

Ka whakatau tō tākuta i te wā e oti ai tō rongoā i runga i te pai o tō urupare ki te rongoā me te hiahia o ngā rongoā whai muri. Kotahi noa te wāhanga e hiahiatia ana e ētahi tāngata, ētahi atu rānei e hiahiatia ana e rātou ētahi rongoā i horahia i roto i ngā marama.

Ka taea e au te taraiwa i muri i te tango waikawa Aminolevulinic?

Me karo koe i te taraiwa i muri i te tango waikawa aminolevulinic, ina koa i te rā o te rongoā. Ka taea e te rongoā te whakapōrearea, te whakapairuaki, me te ngenge ka raru pea tō kaha ki te taraiwa haumaru.

I tua atu, me karo koe i te pānga o te mārama kanapa mō te 24-48 haora i muri i te rongoā, kei roto i tēnei te rā kanapa ka kitea e koe i te wā e taraiwa ana. Whakaritea kia whai tangata hei taraiwa i a koe ki te haere me te hoki mai i ō whakaritenga rongoā me te iti rawa i te rā tuatahi i muri i ia wāhanga.