He aha te Aztreonam: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

He paturopi rongoā a Aztreonam e whakamahia ana e ngā tākuta hei rongoā i ngā mate huakita kino. No tētahi momo paturopi motuhake e kīia ana ko monobactams, e mahi rerekē ana i te penicillin me ētahi atu paturopi noa.

Ka hoatu tēnei rongoā mā te raina IV (intravenous) rānei, he werohanga rānei ki roto i tō uaua. Ka whakamahia e tō rōpū hauora te aztreonam i te nuinga o te wā kāore i whai hua ētahi atu paturopi, i te wā rānei e pangia ana koe e te huakita e ātete ana ki te maha o ētahi atu rongoā.

He aha te Aztreonam e whakamahia ana mō?

Ka rongoā a Aztreonam i ngā mate huakita kino ka mōrearea te ora ki te kore e rongoātia. Ka tohua e ngā tākuta i te wā e hiahia ana rātou ki tētahi paturopi kaha ka taea te tae atu ki ngā wāhi kua pangia mā tō toto.

He pai te mahi a tēnei rongoā ki ētahi momo huakita e kīia ana ko te huakita gram-negative. He anga whakamarumaru tō ēnei huakita e uaua ai te rongoā ki ngā paturopi noa.

Ngā mate noa e rongoātia ana ki te aztreonam ko:

• Pneumonia me ētahi atu mate pūkahukahu kino
• Ngā mate ara mimi kua horapa ki ō tākihi
• Ngā mate puku, tae atu ki ērā e pā ana ki ō whekau, ki tō ate rānei
• Ngā mate kiri me ngā kiko ngawari kua hōhonu
• Ngā mate toto (sepsis)
• Ngā mate wheua me ngā hononga

Ka whakamahi pea tō tākuta i te aztreonam ki te mate pāwera koe ki te penicillin, ki ētahi atu paturopi beta-lactam rānei. E whakaarohia ana he haumaru ake mō ngā tāngata e pāwera ana ki ēnei mea nā te mea he rerekē tōna hanganga matū.

Me pēhea te mahi a Aztreonam?

He paturopi kaha a Aztreonam e mahi ana mā te wawahi i ngā pakitara pūtau o te huakita. Whakaarohia ngā pakitara pūtau huakita me te anga whakamarumaru huri noa i te hua manu - ka pakaru te anga nei e te aztreonam, kāore e ora te huakita.

E whāinga ana tēnei rongoā ki tētahi whākōrere e kīia ana ko te transpeptidase e hiahiatia ana e ngā huakita hei hanga me te tiaki i ō rātou pakitara pūtau. Ki te aukati a aztreonam i tēnei whākōrere, ka pakaru ngā huakita, ka mate.

Ko te mea motuhake mō aztreonam he pānga anake ki ētahi momo huakita. He tino whai hua ki ngā huakita gram-negatīwi engari kāore e whai hua ki ngā huakita gram-positīwi, ki ngā harore rānei. Ka whai hua tēnei huarahi whāinga i te wā e mōhio ana tō tākuta ki te momo mate e pā ana ki a koe.

Me pēhea taku tango i te Aztreonam?

Ka hoatu tonu a Aztreonam e ngā tāngata ngaio hauora i roto i te hōhipera, i te whare haumanu rānei. E kore koe e tango i tēnei rongoā i te kāinga nā te mea me whakarite hou, me hoatu mā te rārangi IV, mā te werohanga rānei.

Ka hoatu e tō nēhi, e tō tākuta rānei te aztreonam ki a koe mā te uaua (intravenously) mā te werohanga rānei ki roto i te uaua nui, te nuinga i tō pūtake, i tō huha rānei. He mea noa te tikanga IV mō ngā mate kino nā te mea ka tere te rongoā ki roto i tō toto.

Kāore koe e mōhio ki te tango i tēnei rongoā me te kai nā te mea ka haere tika ki roto i tō toto. Heoi, ko te noho pai te wai mā te inu nui i te wai ka āwhina i ō pūkahukahu ki te tukatuka i te rongoā i te whai hua.

Ko te rongoā te nuinga ka hoatu ia 6 ki te 12 hāora, i runga i te kaha o tō mate me te pēhea te urupare o tō tinana ki te rongoā. Ka mātakitaki tata tō rōpū hauora i a koe, ā, ka whakatika pea i te wā i runga i tō ahunga whakamua.

Kia pēhea te roa o taku tango i te Aztreonam?

Ko te roa o tō rongoā aztreonam e whakawhirinaki ana ki te momo me te kaha o tō mate. Ko te nuinga o te tangata ka whiwhi i tēnei rongoā mō te 7 ki te 14 rā, engari ko ētahi mate ka hiahiatia he rongoā roa ake.

Ka whakatau tō tākuta i te roa tika i runga i ētahi mea. Kei roto i tēnei te tere o te urupare o tō mate, te momo huakita e pā ana ki te raruraru, me tō āhua hauora whānui.

Mō te pūkahukahu, ngā mate rānei o te pūkahukahu, tērā pea ka hiahia koe ki te aztreonam mō te 10 ki te 14 rā. Ko ngā mate o te ara mimi e hiahia ana kia 7 ki te 10 rā te rongoā. Ko ngā mate uaua ake pērā i te puku, i ngā wheua rānei, tērā pea ka hiahia rongoā mō ētahi wiki.

He mea nui kia whakaoti i te akoranga rongoā katoa ahakoa ka tīmata koe ki te pai ake. Ko te whakamutu i te paturopi i te wā wawe rawa ka taea e te mate te hoki mai i te kaha ake, ā, ka tūpono ka pūngāwari ki te rongoā.

He aha ngā pānga taha o te Aztreonam?

Pērā i ngā rongoā katoa, ka taea e te aztreonam te pānga taha, ahakoa he maha ngā tāngata e pai ana ki te tango. Ko te nuinga o ngā pānga taha he ngawari, ka ngaro i te otinga o tō rongoā.

Ko ngā pānga taha tino noa ka pā ki a koe ko:

• Te mamae, te pūhi, te whero rānei i te wāhi werohanga
• Te whakapairuaki, te puku rānei
• Te korere
• Te ānini
• Te whanoke
• Te mōmona kiri

Ko ēnei tohumate te tikanga ka pai ake i te wā e urutau ana tō tinana ki te rongoā. Ka aroturukihia koe e tō rōpū hauora mō ngā tauhohenga, ā, ka taea e rātou te whakarato rongoā hei āwhina i te whakahaere i ngā pānga taha e kore e pai.

Ka pā pea ki ētahi tāngata ngā pānga taha nui ake e hiahia ana kia aro mai te rongoā tonu:

• Ngā tauhohenga mate pāwera nui me te uaua ki te manawa, te pūhi rānei o tō mata me tō korokoro
• Te korere nui pea kei roto te toto
• Te pāpāhua, te toto rānei e kore e noa
• Te kōwhai o tō kiri, o ō kanohi rānei
• Te raruraru, te hopu rānei

He pānga taha onge engari he nui hoki ka pā ki te iti iho i te 1% o ngā tāngata e tango ana i te aztreonam. Kei roto i ēnei ko ngā tauhohenga kiri nui, ngā raruraru ate, me ngā huringa i roto i ō tatauranga pūtau toto. Ka mātakitaki tō rōpū hauora mō ēnei mā te aroturuki me ngā whakamātautau toto.

Ko wai kāore e tika kia tango Aztreonam?

He pai te nuinga o te wā ki te tango aztreonam, engari he wāhi ka whiriwhiri tō tākuta i tētahi rongoā paturopi rerekē. Ko te āwangawanga nui ko te mea kua pā mai he pānga mate pāwera ki a koe i te aztreonam i mua.

Me whakatika pea te horopeta, me mātakitaki rānei i ngā tāngata e tino mate ana i te pūkahukahu. I te mea ka āwhina ō pūkahukahu ki te tango aztreonam i tō tinana, ka taea e te mahi pūkahukahu kua heke te rongoā ki te piki ake.

Ka tūpato anō tō tākuta ki te mea kei a koe:

• He hītori o te mate ate nui
• He mate toto, he iti rānei te tatau o te pātirotiro
• He hītori o te hopu, o ngā mate roro rānei
• He mate mumura i te puku, pēnei i te mate a Crohn, i te colitis ulcerative rānei

Me whai whakaaro motuhake te hapū me te whāngai u. Ahakoa e kiia ana he pai te aztreonam i te wā e hapū ana, ka whakataurite tō tākuta i ngā painga ki ngā tūponotanga ka pā ki tō pēpi.

Ngā Ingoa Waitohu Aztreonam

Kei te wātea te Aztreonam i raro i ētahi ingoa waitohu, ko Azactam te mea tino noa i te United States. Ka kite pea koe i te ingoa Cayston, he momo motuhake e ngāia ana hei rongoā i ngā mate pūkahukahu i ngā tāngata e mate ana i te cystic fibrosis.

Kei te wātea hoki ngā momo aztreonam generic, ā, he rite tonu te whai hua ki ngā momo waitohu. Ka whakamahi tō hōhipera, tō whare haumanu rānei i te momo kei a rātou, ā, kei roto i ngā momo katoa te whakauru kaha kotahi.

Ngā Kōwhiringa Aztreonam

Ki te kore te aztreonam te kōwhiringa tika mō tō mate, he maha ētahi atu rongoā paturopi kaha hei whakaaro mā tō tākuta. Ko te kōwhiringa pai rawa atu ka whakawhirinaki ki te momo huakita e pā ana ki tō mate me tō hītori hauora.

Ko ngā kōwhiringa noa ko ngā fluoroquinolones pēnei i te ciprofloxacin, i te levofloxacin rānei, ka taea te rongoā i te maha o ngā mate rite tonu ki te aztreonam. Mō ētahi mate, ka whiriwhiri pea tō tākuta i ngā aminoglycosides pēnei i te gentamicin, i te tobramycin rānei.

Ko ngā paturopi Carbapenem pēnei i te meropenem, i te imipenem rānei tētahi atu kōwhiringa mō ngā mate kino. E mahi ana ēnei rongoā ki te whānuitanga o ngā huakita i te aztreonam, engari he rerekē pea ngā pānga taha.

Ka whiriwhiria e tō tākuta te kōwhiringa pai rawa atu i runga i tō āhuatanga motuhake, tae atu ki ngā mate pāwera kei a koe me ngā hua o ngā whakamātautau e tautuhi ana i ngā huakita e pā ana ki tō mate.

He Pai Anei te Aztreonam i te Ceftriaxone?

He paturopi kaha te Aztreonam me te ceftriaxone, engari e mahi ana rāua ki ngā momo huakita rerekē. Kāore tētahi e pai ake ana i tētahi – kei runga i tō mate motuhake me tō āhuatanga hauora te kōwhiringa tika.

No te akomanga cephalosporins te ceftriaxone, ā, e mahi ana ki ngā huakita gram-positive me te gram-negative. Nō reira he whai hua mō te whānuitanga o ngā mate kaore e mōhio ana ngā tākuta he aha ngā huakita e rongoā ana rātou.

Ko te Aztreonam, i tērā taha, e mahi ana ki ngā huakita gram-negative anake, engari he tino whai hua ki ēnei momo. He maha ngā wā ka whiriwhiria i te wā kāore i whai hua ētahi atu paturopi, i te wā rānei e pāwera ana koe ki ngā rongoā momo penicillin.

Ko te painga nui o te aztreonam ko tōna āhuatanga haumaru mō ngā tāngata e pāwera ana ki te penicillin. I ētahi wā ka pā mai ngā tauhohenga pāwera i te ceftriaxone ki ngā tāngata e pāwera ana ki te penicillin, engari he haumaru te aztreonam mō ēnei tāngata.

Ngā Pātai Auau mō Aztreonam

Q1. He Haumaru te Aztreonam mō ngā Tāngata e Mate ana i te Whatumanawa?

Ka taea te whakamahi i te Aztreonam ki ngā tāngata e mate ana i te whatumanawa, engari ka whakatika pea tō tākuta i te horopeta me te aroturuki i a koe. I te mea e āwhina ana ō whatumanawa ki te tango i te aztreonam i tō tinana, ko te iti o te mahi whatumanawa te tikanga ka noho roa te rongoā i roto i tō pūnaha.

Ka tirohia e tō rōpū hauora te mahi o ō pūkahukahu ki ngā whakamātautau toto i mua i te tīmatanga o te rongoā, ā, ka haere tonu pea te aroturuki i te wā o te rongoā paturopi. Ka hoatu pea e rātou he horopeta iti ake, ka whakanui rānei i te wā i waenga i ngā horopeta hei aukati i te rongoā kia kaua e piki ki ngā taumata kino.

Q2. Me Pēhea Taku Mahi Mēnā he Pānga Tauhohe Taku ki te Aztreonam?

Mēnā ka puta ngā tohu o te pānga tauhohe i te wā e whiwhi ana koe i te aztreonam, kōrero tonu ki tō rōpū hauora. Ko ngā tauhohe ngawari pēnei i te pānga kiri ka taea te whakahaere ki ngā antihistamines i te wā e haere tonu ana tō rongoā.

Ko ngā tauhohe tauhohe nui e hiahia ana ki te āwhina hauora tonu. Ko ngā tohu ko te uaua ki te manawa, te pūhi o tō mata, korokoro rānei, te whanoke nui, te tere rānei o te ngākau. I te mea kei te whiwhi koe i te aztreonam i roto i te taiao hauora, kua rite tō rōpū hauora ki te whakahaere i ēnei āhuatanga i te tere me te whai hua.

Q3. Me Pēhea Taku Mahi Mēnā Kua Ngaro Taku Horopeta Aztreonam?

I te mea ka hoatu te aztreonam e ngā tākuta hauora i roto i te hōhipera, i te whare haumanu rānei, kāore koe e mōhio ki te māharahara mō te ngaro i ngā horopeta. E whai ana tō rōpū hauora i tētahi hōtaka tino tika kia mōhio ai koe ka whiwhi koe i ia horopeta i te wā tika.

Mēnā he take i whakaroa ai tētahi horopeta nā te tikanga hauora, i ētahi atu rongoā rānei, ka whakatika tō rōpū hauora i tō hōtaka kia rite. Ka mōhio rātou ka whiwhi tonu koe i te rongoā katoa e hiahiatia ana e tō mate.

Q4. Āhea Taku Mutu i te Tango Aztreonam?

Ka whakatau tō tākuta i te wā hei mutu i tō rongoā aztreonam i runga i te pai o te urupare o tō mate. Ka titiro rātou ki ngā āhuatanga pēnei i ō tohu, ngā hua o te whakamātautau toto, me ētahi atu rangahau whakaahua hei whakatau i te wā e whakahaerehia ana te mate.

Kaua rawa e tono kia mutu wawe te rongoā, ahakoa kei te pai ake koe. Ka taea e ngā mate huakita te hoki mai i te kaha ake mēnā kāore i te whakakorehia katoatia, ā, ko te whakamutu i ngā paturopi i te wā wawe rawa ka arahi ki te aukati paturopi.

Q5. Ka taea e au te inu waipiro i te wa e tango ana i te Aztreonam?

Ahakoa karekau he pānga tika a aztreonam ki te waipiro, he pai ake te karo i te inu i te wa e rongoa ana koe i te mate kino. Ka taea e te waipiro te whakararu i te kaha o to tinana ki te whawhai i te mate, ka kino pea etahi paanga taha penei i te nausea, te whanoke ranei.

Me whai kaha me nga rauemi katoa to tinana ki te whawhai i te mate me te whakaora. Ka taea hoki e te waipiro te pa ki te kaha o to ate ki te tukatuka i nga rongoa, ka whakararu pea i to moe me to whakaora. Arotahi ki te noho wai ki te wai me te okioki nui.