He aha te Bevacizumab: Ngā Whakamahinga, te Inenga, Ngā Pānga Taha me Ētahi Atu

He rongoā mate pukupuku whāinga a Bevacizumab e āwhina ana ki te whawhai i ētahi momo mate pukupuku mā te tapahi i ō rātou tūhononga toto. E mahi ana tēnei rongoā mā te aukati i tētahi pūmua e kīia ana ko VEGF e āwhina ana i ngā puku ki te whakatipu i ngā oko toto hou hei whāngai i a rātou anō.

Ka tūtohu pea tō tākuta i te bevacizumab mēnā he mate pukupuku motuhake ō koe pēnei i te colorectal, te pūkahukahu, te whatukuhu, te puku roro rānei. Ka hoatu tonu mā te IV i roto i te hōhipera, i te whare haumanu rānei, i reira ka taea e ngā tākuta te aroturuki i a koe i te wā o te maimoatanga.

He aha te Bevacizumab?

He paturopi i hangaia i te taiwhanga a Bevacizumab e whāinga ana i ngā pūtau mate pukupuku i tētahi ara tino motuhake. Whakaarohia he kaitiaki tino whakangungua e mōhio ana, e aukati ana i ētahi tohu e whakamahia ana e ngā pūtau mate pukupuku ki te tipu me te horapa.

No tētahi rōpū rongoā tēnei rongoā e kīia ana ko ngā aukati angiogenesis, ko te tikanga e aukati ana i te hanganga o ngā oko toto hou. E hiahia ana ngā pūtau mate pukupuku ki te tuku tonu o ngā matūkai me te hāora mā ngā oko toto kia ora ai, kia nui haere ai. Mā te aukati i tēnei tūhononga toto, ka whakamate te bevacizumab i te puku.

E mōhiotia ana te rongoā i tōna ingoa waitohu Avastin, ā, ka tae mai i te wai mārama e whakaranuhia ana e ngā kaiwhakarato hauora ki te otinga tote. E kiia ana he paturopi monoclonal, ko te tikanga i hangaia hei whāinga i tētahi pūmua motuhake i tō tinana.

He aha te Bevacizumab e whakamahia ana?

E rongoā ana a Bevacizumab i ētahi momo mate pukupuku matatau, i te nuinga o te wā i te taha o ētahi atu rongoā mate pukupuku. Māu e whakatau tō tākuta mate pukupuku mēnā he tika tēnei maimoatanga mō tō āhuatanga motuhake i runga i tō momo mate pukupuku me te wāhanga.

Koinei ngā mate pukupuku matua e āwhina ai te bevacizumab:

• Te mate pukupuku o te puku me te whekau kua horapa ki ētahi atu wāhi o tō tinana
• Te mate pukupuku pūkahukahu kore-iti i ngā wāhanga whakamua
• Te mate pukupuku whatukuhu (te pūkahukahu pūtau whatukuhu)
• Ngā puku roro, otirā te glioblastoma
• Te mate pukupuku o te kaki kōpū kua hoki mai, kua horapa rānei
• Te mate pukupuku o te pūkahukahu kua hoki mai i muri i te maimoatanga tuatahi

Ka whakaaro pea tō tākuta ki te whakamahi i te bevacizumab mō ētahi atu momo mate pukupuku i roto i ngā whakamātau haumanu, i ngā āhuatanga motuhake rānei. He iti noa te whakamahi i te rongoā nei anake, ā, te nuinga ka mahi tahi me ngā rongoā matū hei whakanui i tō rātou whai huatanga.

Me pēhea te mahi a te Bevacizumab?

Ka mahi te bevacizumab mā te whai i tētahi pūmua e kīia ana ko te vascular endothelial growth factor, arā, ko VEGF mō te poto. Ko tēnei pūmua e mahi ana hei tohu e kī ana ki tō tinana kia hanga ngā oko toto hou, he mahi hauora tēnei i te nuinga o te wā.

Ka tahae ngā pūtau mate pukupuku i tēnei mahi māori mā te whakaputa i te nui rawa o te VEGF hei hanga i tā rātou ake whatunga oko toto. Ko ēnei oko hou e kawe ana i te hāora me ngā matūkai hei āwhina i ngā puku kia nui ake, kia horapa pea ki ētahi atu wāhi o tō tinana.

Ka uru te bevacizumab ki tō pūnaha, ka herea ki ngā pūmua VEGF, ā, ka ārai i a rātou ki te tuku i ā rātou tohu hanga oko toto. Ko tēnei mahi e tapahi ana i te pūtake kai o te puku, e pā ana ki te whakaheke, ki te aukati rānei i tōna tipu.

E whakaarohia ana he kaha te rongoā nei, ā, te nuinga ka kitea ngā pānga i roto i ētahi huringa maimoatanga. Heoi, he rerekē tōna mahi i ngā rongoā matū tuku iho e patu tika ana i ngā pūtau mate pukupuku.

Me pēhea taku tango i te Bevacizumab?

Ka tukuna tonu te Bevacizumab mā te raina intravenous (IV) i roto i te hōhipera, te whare haumanu, te whare maimoatanga mate pukupuku rānei. Kāore e taea e koe te tango i tēnei rongoā i te kāinga, mā te waha rānei, me āta whakarite, me te aroturuki e ngā tāngata ngaio hauora.

Ko te tikanga o tō rongoā ka pēnei: Tuatahi, ka kuhu te nēhi i te raina IV ki tō ringa, ki te wāhi uru rānei mō tō pōti, ki te mea he pōti tōu. Ka whakaranuhia te rongoā ki te wai tote, ka hoatu pōturi ana i roto i te 30 ki te 90 meneti.

I mua i ia whakaurunga, kāore koe e hiahia ki te karo i te kai, i te inu rānei, ki te kore e hoatu e tō tākuta ētahi tohutohu motuhake. Heoi anō, mā te noho wai pai mā te inu wai nui i ngā rā i mua i te rongoā ka āwhina i tō tinana ki te tukatuka pai ake i te rongoā.

Ka whiwhi koe i te bevacizumab ia 2 ki te 3 wiki, i runga i tō mahere rongoā. Ka roa pea ia wāhanga i te 2 ki te 4 haora katoa, tae atu ki te wā whakarite me te aroturuki i muri mai.

Kia Pēhea te Roa e Tango Ana ahau i te Bevacizumab?

Ko te roa o tō rongoā bevacizumab e whakawhirinaki ana ki te pai o te urupare a tō mate pukupuku me te pēhea te aro o tō tinana ki te rongoā. Ko te nuinga o te tangata e rongoā ana mō ētahi marama, ahakoa ka hiahia ētahi mō te tau, neke atu rānei.

Ka aroturukihia e tō tākuta mate pukupuku tō haere mā ngā karapa me ngā whakamātautau toto i ngā wā katoa hei whakatau i te wā ki te haere tonu, ki te whakatika, ki te whakamutu rānei i te rongoā. Ki te whakaheke, ki te mutu rānei te tipu o tō mate pukupuku me te kore he pānga taha nui, ka taea e koe te haere tonu i te rongoā mō te wā roa.

Ka hiahia pea ētahi tangata ki te okioki i te rongoā mō te wā poto ki te whanake ētahi pānga taha, ka hoki anō ki te rongoā i te wā e ngaro ana ēnei take. Ka mahi tō tākuta ki a koe ki te kimi i te taurite tika i waenga i te whawhai i tō mate pukupuku me te pupuri i tō kounga o te ora.

He Aha ngā Pānga Taha o te Bevacizumab?

Pērā i ngā rongoā mate pukupuku katoa, ka taea e te bevacizumab te pānga taha, ahakoa kāore te katoa e pā ana ki a rātou. Ko te nuinga o ngā pānga taha ka taea te whakahaere mā te manaaki hauora tika me te aroturuki.

Ngā pānga taha noa e pā ana ki te nuinga o te tangata ko:

• Te pēhanga toto tiketike ka mātakitaki pū mai tō tākuta
• Te ngenge ka nui ake pea tō pōuri i te tikanga
• Ngā mamae mahunga ka taea te whakahaere ki ngā rongoā mamae kaore e hiahiatia he whakahaunga
• Te whakapairuaki ka pā pea ki tō hiahia kai
• Te korere, ngā rānei huringa i ngā nekehanga whekau
• Te ihu toto, te toto rānei e mutu noa ana
• Ngā huringa i te reka ka rerekē pea te reka o te kai

Ko ēnei pānga taha o ia rā ka pai ake i te wā e urutau ana tō tinana ki te rongoā, ā, he maha ngā huarahi hei āwhina i tō rōpū hauora ki te whakahaere i a rātou.

Ko ngā pānga taha kāore i te pūnoa engari he nui ake te kino, me whai wāhi tonu te āwhina hauora, kei roto:

• Te toto nui kāore e mutu noa ana
• Ngā pūhui toto ka pā pea ki te mamae waewae, ngā rānei raruraru manawa
• Te pēhanga toto tiketike rawa me ngā tohumate pēnei i te mamae mahunga nui, ngā rānei huringa tirohanga
• Ngā raruraru tākihi ka pā pea ki te pūhihi, ngā rānei huringa i te mimi
• Ngā raruraru ngākau ka pā pea ki te mamae uma, te poto rānei o te manawa
• Te poka whekau, e pā ana ki te mamae puku nui

Ka mātakitaki pū mai tō rōpū hauora i a koe mō ēnei pānga nui ake, ā, ka whakaako i a koe i ngā tohu whakatūpato hei mātakitaki i waenga i ngā maimoatanga.

Ko ngā raruraru kāore i te pūnoa engari he nui te kino ka puta i roto i te ōrau iti o ngā tūroro, kei roto:

• Ngā raruraru whakaora patunga nui ka whakaroa pea i te pokanga
• Te mate roro whakamuri (RPLS), e pā ana ki te roro
• Te pūmua nui i te mimi (proteinuria)
• Te rahunga ngākau i roto i ngā tāngata e pā ana ki ngā mate ngākau
• Ngā tauhohenga pāwera nui i te wā o te whakaurunga

Ahakoa te ahua o ēnei pānga kāore i te pūnoa, kua whakangungua tō rōpū hauora ki te mōhio me te whakahaere i a rātou i te wā e puta ana.

Ko wai kāore e tika kia tango Bevacizumab?

Kāore i te haumaru te Bevacizumab mō te katoa, ā, ka āta tātari tō tākuta i tō hītori hauora i mua i te tūtohu i tēnei rongoā. Ko ētahi āhuatanga hauora, ā, ko ētahi wāhanga ka waiho tēnei rongoā hei mea mōrearea.

Kāore koe e whiwhi bevacizumab mēnā he:

• He pokanga tata i roto i ngā rā 28 kua pahure, nā te mea ka raru pea te whakaora i ngā patunga
• Te toto e kaha ana, he hītori rānei mō ngā mate toto nui
• Te pēhanga toto tiketike, kāore i te whakahaerehia
• He whakaeke ngākau tata, he whiu rānei
• He mate tākihi nui, he pūmua rānei i roto i te mimi
• He mate pāwera mō te bevacizumab, mō ngā rongoā rite rānei

Ka tūpato anō tō tākuta mēnā he mate ngākau tōu, he mate toto rānei, he hītori rānei mō ngā raruraru whekau. Kāore ēnei āhuatanga e whakakore aunoa i a koe i te rongoā, engari me mātakitaki tata.

Mēnā kei te hapū koe, kei te whāngai ū rānei, kāore i te tūtohutia te bevacizumab nā te mea ka whara i tō pēpi e tipu ana. Ka kōrero tō rōpū hauora mō ngā tikanga aukati hapū haumaru mēnā kei te tau whānau tamariki koe.

Ngā Ingoa Waitohu Bevacizumab

Ko te bevacizumab te mea e mōhiotia ana e te ingoa waitohu Avastin, koinei te putanga taketake i whakawhanakehia e Genentech. Koinei te ingoa ka rongo pea koe mai i tō rōpū hauora, ka kite hoki i runga i ō pepa rongoā.

He maha ngā putanga koiora o te bevacizumab kua whakaaetia, ā, kei te wātea pea i tō pokapū rongoā. Kei roto i ēnei ko Mvasi, Zirabev, me Alymsys, e mahi ana i te ara kotahi me te Avastin taketake.

He tino rite ngā koiora ki te rongoā taketake, ā, he rite te whai huatanga me te haumaru. Ka whakamahi pea tō tākuta, tō kaimātai rongoā rānei i ēnei ingoa i te wā e kōrero ana mō tō rongoā, engari e pā ana katoa ki te momo rongoā kotahi.

Ngā Kōwhiringa Bevacizumab

Ki te kore a bevacizumab e tika ana mōu, ki te mutu rānei te mahi whai hua, he maha ngā kōwhiringa rongoā kē atu kei tō tākuta mate pukupuku. Ko te kōwhiringa pai rawa atu ka whakawhirinaki ki te momo mate pukupuku e pā ana ki a koe me tō āhua hauora whānui.

Ko ētahi atu aukati angiogenesis e mahi ana i te ara rite ko:

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• Ramucirumab (Cyramza) mō te mate pukupuku puku me te pūkahukahu
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• Sunitinib (Sutent) mō te mate pukupuku whatukuhu
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• Sorafenib (Nexavar) mō te mate pukupuku ate me te whatukuhu
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• Pazopanib (Votrient) mō te mate pukupuku whatukuhu
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Ka whakaaro pea tō tākuta ki ngā rongoā immunotherapy, ngā huinga chemotherapy rerekē, ngā pire rongoā whai wāhi rānei i runga i tō āhuatanga. He painga me ōna ake pānga taha tēnā kōwhiringa kē atu.

He maha ngā wā ka whai wāhi ngā whakamātau haumanu ki ngā rongoā hou kāore anō kia wātea whānuitia. Ka āwhina tō tākuta mate pukupuku i a koe ki te tūhura i ēnei kōwhiringa mēnā kāore ngā rongoā paerewa e tika ana.

He Pai Ake Anei a Bevacizumab i Ētahi Atu Rongoā Mate Pukupuku?

Kāore a Bevacizumab i te pai ake, i te kino ake rānei i ētahi atu rongoā mate pukupuku, engari he rerekē te kaupapa i roto i tō mahere rongoā. He maha ngā wā ka whai hua rawa atu i te wā e honoa ana ki ngā rongoā chemotherapy tuku iho, kaua ki te whakamahi takitahi.

Ki te whakataurite ki te chemotherapy anake, ka āwhina te tāpiri i te bevacizumab ki te whakaheke i ngā puku i te ara whai hua ake, ā, i ētahi wā ka āwhina i te tangata kia roa ake te ora. Heoi anō, ka tāpirihia hoki ngā pānga taha ka āta whakahaerehia e tō rōpū hauora.

Ko te

He Haumaru te Bevacizumab mō te hunga mate ngākau?

Me tūpato anō te Bevacizumab mō te hunga e pā ana ki te mate ngākau, engari kāore e whakakorehia aunoa. Ka mahi tahi tō tākuta ngākau me tō tākuta mate pukupuku ki te whakatau mēnā he nui ake ngā painga i ngā tūponotanga mō tō āhuatanga motuhake.

Mēnā he mate ngākau tōu, ka mātakitaki anō tō rōpū hauora i te mahi o tō ngākau i te wā o te rongoā. Ka whakatika pea rātou i tō inenga, ka whakarite i ngā aroturuki auau, ka tūtohu rānei i ngā rongoā tiaki ngākau i te taha o tō rongoā mate pukupuku.

Me pēhea ahau ki te whiwhi ohorere i te nui rawa o te Bevacizumab?

He tino kore pea te nui rawa o te bevacizumab i te mea e tino tatau ana, e whakahaere ana ngā tāngata ngaio hauora i ia inenga. Ka tukuna te rongoā mā te IV i te wā e aroturukihia ana koe, e kore ai e taea te nui rawa o te horopeta.

Mēnā e māharahara ana koe mō tō inenga, e pā ana rānei ki ngā tohumate rerekē i muri i te rongoā, whakapā atu ki tō rōpū mate pukupuku tonu. Ka taea e rātou te aromātai i ō tohumate me te whakarato i te manaakitanga e tika ana ki te hiahiatia.

Me pēhea ahau ki te ngaro i te inenga o te Bevacizumab?

Mēnā ka ngaro koe i tētahi whakaritenga bevacizumab, whakapā atu ki tō rōpū mate pukupuku i te wa e taea ai ki te whakarite anō. Ka whakatau rātou i te wā pai mō tō inenga e whai ake nei i runga i tō hōtaka rongoā me te nui o te wā kua pahemo.

Kaua e ngana ki te utu i ngā inenga kua ngaro mā te whakarite i ngā rongoā kia tata tahi. Ka whakatika tō rōpū hauora i tō mahere rongoā kia haumaru ai koe ki te ara tika i te wa e mau tonu ana te whai huatanga o te rongoā.

Āhea ahau e mutu ai te tango i te Bevacizumab?

Me mutu anake te rongoā bevacizumab i raro i te aratohu a tō tākuta mate pukupuku, ahakoa kei te pai koe. He uaua ngā whakatau rongoā mate pukupuku, ā, i runga i ngā hua o te karapa, ngā whakamātautau toto, me tō urupare whānui ki te rongoā.

Ka arotakehia e tō tākuta i ngā wā katoa mēnā ka haere tonu, ka whakarerekē, ka whakamutu rānei i tō rongoā i runga i te pai o te mahi me te pēhea o tō whakamanawanui. Ko ētahi tāngata tērā pea me whakamutu i te mea he pānga kino, engari ko ētahi ka haere tonu mō ngā marama maha mēnā he whai hua te rongoā.

Ka Taea e Au te Kōrero i ngā Kānano i te wā e tango ana i te Bevacizumab?

Ko te nuinga o ngā kānano auau he haumaru i te wā e whiwhi ana i te bevacizumab, engari me tirotiro tonu koe ki tō rōpū oncology tuatahi. Ka tūtohu pea rātou i te wā o ngā kānano i waenga i ngā huringa rongoā, i te karo rānei i ngā kānano ora i te wā o tō rongoā.

Kāore pea tō pūnaha ārai mate e whakahoki kaha ki ngā kānano i te wā e tango ana i te rongoā mate pukupuku, nō reira tērā pea ka tūtohu tō tākuta i ētahi atu whakatūpato, i ngā pūhi whakanui rānei. Kia mōhio tō rōpū hauora ki ngā kānano katoa e whakaaro ana koe.