He aha te Bevacizumab-tnjn: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

Ko te Bevacizumab-tnjn he rongoā mate pukupuku e whai ana ki te ārai i te tipu o te puku mā te aukati i te hanganga o ngā oko toto. No roto tēnei rongoā i tētahi rōpū rongoā e kīia ana ko ngā paturopi monoclonal, e mahi ana pērā i ngā pūoro ārahi ki te kimi me te whakaeke i ngā pūmua motuhake e hiahia ana ngā pūtau mate pukupuku kia ora ai, kia horapa ai.

Tērā pea ka pōuri koe i te ako mō tēnei rongoā, ā, he mea tūturu tēnā. Mā te māramatanga ki te mahi o tō rongoā e āwhina i a koe kia māia ake mō tō mahere rongoā me ngā mea e tūmanakohia ana i te ara.

He aha te Bevacizumab-tnjn?

Ko te Bevacizumab-tnjn he putanga koiora o te rongoā bevacizumab taketake. Ko te tikanga o te koiora he tino rite ki te rongoā taketake i runga i te haumaru me te whai hua, engari he mea hanga e tētahi kaihanga rerekē mā te whakamahi i ngā tukanga rerekē.

Ko tēnei rongoā he paturopi i hangaia i te taiwhanga e whai ana i te pūnaha ārai mate tūturu o tō tinana. E whai ana i tētahi pūmua e kīia ana ko VEGF (vascular endothelial growth factor), e whakamahia ana e ngā puku ki te hanga i ngā oko toto hou. Mā te aukati i tēnei pūmua, ka āwhina te rongoā i ngā puku kia kore he kai e hiahiatia ana e rātou kia tipu.

Ko te wāhanga "-tnjn" o te ingoa he kupu tāpiringa noa iho e āwhina ana ki te wehe i tēnei koiora motuhake i ētahi atu. Whakaarohia pērā i te ingoa whakamutunga e āwhina ana ki te tautuhi i te putanga motuhake o te rongoā e whiwhi ana koe.

He aha te Bevacizumab-tnjn e whakamahia ana mō?

Ka rongoā te Bevacizumab-tnjn i ētahi momo mate pukupuku mā te whai i te tuku toto e whāngai ana i ngā puku. Kua tohua tēnei rongoā e tō tākuta nā te mea ka āwhina i te whakaroa i te tipu o te mate pukupuku, ā, ka whakaiti pea i ngā puku e noho ana.

Ka whakamahia te rongoā mō ēnei momo mate pukupuku motuhake:

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• Te mate pukupuku o te kōpū me te nono (te mate pukupuku o te kōpū, te nono rānei)
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• Te mate pukupuku o te pūkahukahu, ina koa te mate pukupuku pūkahukahu kore-iti
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• Te mate pukupuku o te tākihi (te pūkahukahu pūtau tākihi)
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• Te mate pukupuku o te kōpū wahine
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• Te mate pukupuku o te hua manu
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• Glioblastoma (he momo puku roro)
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He maha ngā wā ka whakakotahi tō tākuta mate pukupuku i te bevacizumab-tnjn me ētahi atu rongoā mate pukupuku pērā i te rongoā matū. He pai ake pea tēnei huarahi whakakotahi i te whakamahi i tētahi rongoā anake, e whai wāhi ana koe ki te whai hua pai.

Me pēhea te mahi a Bevacizumab-tnjn?

Ka mahi a Bevacizumab-tnjn mā te tapahi i te tuku toto e hiahiatia ana e ngā puku kia tupu, kia horapa. Koinei te rongoā kaha, ka whai pānga nui ki te haere tonu o te mate pukupuku ina whakamahia tika ana.

Anei te mahi o te tukanga i roto i ngā kupu māmā. Ka tukuna e ngā pūtau mate pukupuku tētahi pūmua e kīia ana ko VEGF, e tohu ana i tō tinana ki te hanga i ngā oko toto hou huri noa i te puku. Ko ēnei oko toto hou e mahi ana hei huarahi nui, e tuku ana i te hāora me ngā matūkai hei āwhina i te mate pukupuku kia tupu, kia horapa ki ētahi atu wāhanga o tō tinana.

Ka aukati a Bevacizumab-tnjn i te VEGF mai i te tuku i ēnei tohu. Ina herea te rongoā ki te VEGF, ka ārai i ngā oko toto hou mai i te hanga huri noa i te puku. Ki te kore tēnei tuku toto, ka uaua te puku ki te tiki i ngā matūkai e hiahiatia ana e ia kia haere tonu te tupu.

Ko tēnei tukanga e kīia ana ko te anti-angiogenesis, ko te tikanga tūturu

Ka whakauruhia e tō rōpū hauora tētahi ngongo iti (raina IV) ki roto i tētahi uaua i tō ringa, ka whakamahi rānei i tētahi raina pokapū mēnā he pērā tōna. Ka whakaranua te rongoā ki te otinga tote, ka whakamakuku pōturi ki roto i tō toto i roto i te 30 ki te 90 meneti. Ko te tikanga ka roa ake tō whakaurunga tuatahi i te mea e aroturukihia ana e tō rōpū hauora te āhua o tō urupare ki te rongoā.

Kāore koe e hiahia ki te tango i tēnei rongoā me te kai, ki te karo rānei i te kai i mua. Heoi, he mea whai hua ki te noho pai te wai mā te inu nui i te wai i mua i muri i tō rongoā. E kitea ana e ētahi tāngata he whakamarie ki te kawe mai i tētahi paramanawa, pukapuka, papa rānei hei āwhina i te wā i te wā o te whakaurunga.

Ka whakawhirinaki tō hōtaka rongoā ki tō momo mate pukupuku me te mahere rongoā whānui. Ko te nuinga o te tāngata ka whiwhi whakaurunga ia 2 ki te 3 wiki, engari mā tō tākuta mate pukupuku e whakatau te wā tika mō tō āhuatanga.

Kia Pēhea Te Roa E Tango Ai Au i te Bevacizumab-tnjn?

Ko te roa o tō rongoā bevacizumab-tnjn ka whakawhirinaki ki te pai o te urupare o tō mate pukupuku me te āhua o tō tinana e whakaae ana ki te rongoā. Ko te nuinga o te tāngata ka haere tonu i te rongoā mō ētahi marama, ahakoa ka hiahia ētahi mō te tau, neke atu rānei.

Ka aroturukihia e tō tākuta mate pukupuku tō haere mā ngā whakamātautau toto, ngā karapa whakaahua, me ngā whakamātautau tinana. Mā ēnei arowhai e āwhina ki te whakatau mēnā kei te whai hua te rongoā, me te kore rānei koe e pā ana ki ētahi pānga taha e pā ana.

Ko te tikanga ka haere tonu te rongoā i te wā e mau tonu ana, e pai ake ana rānei tō mate pukupuku, ā, kāore koe e pā ana ki ngā pānga taha kino. Ka tūtohu pea tō tākuta kia whakamutua te rongoā mēnā e whakaatu ana ngā karapa kei te haere whakamua tō mate pukupuku ahakoa te rongoā, ki te uaua rawa rānei te whakahaere i ngā pānga taha.

He mea nui kia tae ki ngā pōti katoa kua whakaritea, kaua hoki e whakamutu i te rongoā i runga i tō ake. Ki te mea kei te āwangawanga koe mō te haere tonu i te rongoā, kōrerohia ō āwangawanga ki tō rōpū hauora. Ka taea e rātou te āwhina ki te whakatika i tō mahere rongoā, ki te whakarato rānei i te tautoko atu hei āwhina i a koe i ngā wā uaua.

He aha ngā pānga taha o Bevacizumab-tnjn?

Ka taea e Bevacizumab-tnjn te pānga taha nā te mea e pā ana ki te hanganga o ngā oko toto puta noa i tō tinana, ehara i te mea kei te taha noa o ngā puku. Ko te nuinga o te tangata e pā ana ki ētahi pānga taha, engari he maha ngā mea ka taea te whakahaere mā te tiaki tika me te aroturuki.

Ko ngā pānga taha tino noa e pā ana ki te nuinga o te tangata ko:

• Te pēhanga toto tiketike (hypertension)
• Te ngenge me te ngoikore
• Te korere
• Te heke o te hiahia kai
• Te mamae o te upoko
• Te whakapairuaki
• Pūmua i roto i te mimi
• Te ihu toto
• Ngā huringa o te reka

Ka aroturukihia e tō rōpū hauora tō pēhanga toto, ā, ka tohutohu pea i te rongoā hei pupuri i te pēhanga i raro i te mana. Ka tirohia hoki tō mimi i ngā wā katoa kia mōhio ai ki te pūmua, e tohu ana i ngā pānga o te rongoā ki te pūkahukahu.

Ko ētahi pānga taha nui e hiahia ana kia tere te rongoā, ahakoa he iti noa iho. Kei roto i ēnei ko te toto nui, ngā kōpuku toto, ngā raruraru o te ngākau, me te pōturi o te whakaora i ngā patunga. Ka kōrerohia e tō rōpū hauora ēnei tūponotanga ki a koe, me te whakamārama i ngā tohu whakatūpato hei mātakitaki.

Ko ngā raruraru onge engari nui ka uru ki te poka i te whekau (he rua i te pakitara o te whekau), te pēhanga toto tiketike, ngā raruraru rānei ki te whakaora i ngā patunga i muri i te pokanga. Ahakoa he mea whakamataku ēnei, he nui te wheako o tō rōpū hauora ki te whakahaere i ēnei tūponotanga, ā, ka aroturukihia koe i ngā wā katoa o te rongoā.

Ko wai kāore e tika kia tango Bevacizumab-tnjn?

Kāore i te haumaru a Bevacizumab-tnjn mō te katoa, ā, ka arotakehia e tō tākuta tō hītori hauora i mua i te tohutohu. Ko ētahi āhuatanga hauora, āhuatanga rānei ka nui rawa te tūponotanga o tēnei rongoā.

Kāore koe e tika kia whiwhi bevacizumab-tnjn mēnā he āhuatanga ōna e whai ake nei:

• He pokanga nui i tēnei wā (i roto i ngā rā 28 kua pahure)
• Ngā raruraru nui e pā ana ki te toto, ki ngā mate toto rānei
• Ngā pūtau roro kāore anō kia rongoa
• Te ngoikore o te ngākau
• He whakaeke ngākau, he whiu roro rānei i tēnei wā
• Te hapū, te whāngai ū rānei
• Te mate tākihi nui

Ka tūpato anō tō tākuta ki te whakahau i tēnei rongoā mēnā he toto tiketike tōu e uaua ana ki te whakahaere, he hītori o ngā pūtau toto, mēnā rānei kei te whakamahere koe ki te pokanga i tēnei wā. Kāore ēnei āhuatanga e aukati aunoa i te rongoā, engari me nui ake te aroturuki me ngā whakatūpato.

Mēnā kei te hapū koe, ka taea rānei e koe te hapū, he mea nui kia kōrero koe i ngā kōwhiringa whakawhānau ki tō rōpū hauora. Ka taea e Bevacizumab-tnjn te whakaputa i ngā hē whānau nui, nō reira he mea nui te aukati i te hapū i te wā o te rongoā me ngā marama i muri mai.

Ngā Ingoa Waitohu o Bevacizumab-tnjn

Ka hokona a Bevacizumab-tnjn i raro i te ingoa waitohu Mvasi i te United States. Koinei te putanga koiora rite o te rongoā bevacizumab taketake, e hokona ana i raro i te ingoa waitohu Avastin.

E mahi ana ngā rongoā e rua i te ara kotahi, ā, he rite tonu te whai huatanga me ngā kōrero haumaru. Ko te rerekētanga nui ko te iti ake o te utu o Mvasi i te Avastin, ka āwhina i te whakaiti i ngā utu rongoā.

Ka pai pea tāu mahere inihua, te pokapū rongoā rānei ki tētahi putanga i tētahi atu i runga i te utu, te wātea rānei. Ka taea e koe te mōhio kua whai ngā putanga e rua i ngā whakamātautau kaha kia mōhio ai he haumaru, he whai hua hoki mō te rongoā mate pukupuku.

Ngā Kōwhiringa kē mō Bevacizumab-tnjn

He maha atu ngā rongoā e mahi ana i te ara rite ki te bevacizumab-tnjn mā te aro ki te hanga oko toto huri noa i ngā puku. Ka whakaaro pea tō tākuta mate pukupuku ki ēnei kōwhiringa kē mēnā kāore te bevacizumab-tnjn e tika ana mō tō āhuatanga.

Ko ētahi atu rongoā anti-angiogenesis ko:

• Ramucirumab (Cyramza) - whakamahia mō te puku, te pūkahukahu, me te mate pukupuku ate
• Aflibercept (Zaltrap) - whakamahia mō te mate pukupuku colorectal
• Sorafenib (Nexavar) - whakamahia mō te mate pukupuku whatukuhu me te ate
• Sunitinib (Sutent) - whakamahia mō te mate pukupuku whatukuhu me ētahi puku puku

He rerekē ngā pānga taha o ia rongoā, ā, kua whakaaetia mō ngā momo mate pukupuku rerekē. Māu e kōwhiri te kōwhiringa pai rawa atu i runga i tō momo mate pukupuku, te hauora whānui, me te pai o tō urupare ki ngā rongoā o mua.

Ko te kōwhiringa i waenga i ēnei rongoā e pā ana ki ngā āhuatanga pēnei i te mahi whatukuhu, te pēhanga toto, me te tūponotanga o te whakaheke toto. Ka mahi tō rōpū hauora ki a koe ki te kimi i te rongoā e whai hua ana, me ngā pānga taha e taea te whakahaere.

He Pai Anei a Bevacizumab-tnjn i a Avastin?

E kiia ana he rite tonu te whai hua o Bevacizumab-tnjn (Mvasi) me Avastin mō te rongoā mate pukupuku. Kei roto i ngā rongoā e rua te whakauru kaha kotahi, ā, he rite tonu te mahi ki te aukati i te hanganga o ngā oko toto huri noa i ngā puku.

Kua whakatauhia e te FDA he rite tonu te koiora o te bevacizumab-tnjn ki a Avastin, ko te tikanga kāore he rerekētanga nui i roto i te haumaru, i te whai huatanga rānei. Kua whakaatu ngā rangahau he rite tonu ngā putanga me ngā pānga taha o te hunga e whiwhi ana i ngā rongoā e rua.

Ko te painga nui o te bevacizumab-tnjn ko te utu. Hei rite tonu te koiora, he iti ake te utu i te Avastin taketake, e taea ai te whakaiti i ngā utu rongoā mō ngā tūroro me ngā pūnaha hauora.

Ko tō kōwhiringa i waenga i ēnei rongoā ka whakawhirinaki pea ki ngā āhuatanga pēnei i te inihua, ngā manakohanga o te hōhipera, me te wātea. Ka taea e koe te whai māia ka whai hua ngā kōwhiringa e rua ki te whawhai i te mate pukupuku.

Ngā Pātai Auau mō Bevacizumab-tnjn

He Haumaru Anei a Bevacizumab-tnjn mō te Hunga e Mate Pūngāwerewere ana?

Me mātua whakaaroaro a Bevacizumab-tnjn mēnā he mate tō ngākau, engari kāore e whakakorehia aunoatia. Ka pā te rongoā ki te pēhanga toto, ā, ka pōraru pea te ngākau, nō reira me mahi tahi tō tākuta ngākau me tō tākuta mate pukupuku ki te aroturuki i a koe.

Ka tirohia pea e tō rōpū hauora te mahi o tō ngākau i mua i te tīmatanga o te rongoā, ā, ka aroturukihia i ngā wā katoa o tō rongoā. Ka whakatikatikahia pea e rātou āu rongoā ngākau, ka whakarerekē rānei i tō hōtaka rongoā kia noho haumaru ai koe i te wā e whawhai ana ki tō mate pukupuku.

Me Pēhea Taku Mahi Mēnā I Whiwhi Au i te Nui Rawa o Bevacizumab-tnjn?

E kore e puta te nui rawa o te bevacizumab-tnjn nā te mea ka hoatu te rongoā e ngā tāngata hauora i ngā wāhi whakahaere. Heoi, ki te whakapono koe i whiwhi koe i te nui rawa o te rongoā, whakamōhio atu ki tō rōpū hauora tonu.

Ka aroturukihia koe e tō rōpū hauora mō ngā pānga taha, ā, ka whakatikatikahia pea tō hōtaka rongoā. Kāore he rongoā motuhake mō te bevacizumab-tnjn, nō reira ka arotahi te rongoā ki te whakahaere i ngā tohumate ka puta, me te tautoko i ngā tukanga whakaora tūturu o tō tinana.

Me Pēhea Taku Mahi Mēnā I Ngaro Au i te Inenga o Bevacizumab-tnjn?

Mēnā i ngaro koe i tētahi whakaurunga kua whakaritea, whakapā atu ki tō rōpū hauora i te wā e taea ai ki te whakarite anō. Kaua e tatari kia tae rawa ki tō tūpono kua whakaritea, nā te mea he mea nui te pupuri i te wā tika o te rongoā mō te whai huatanga o te rongoā.

Ka whakatau tō tākuta mate pukupuku i te huarahi pai ki te whakahoki i tō rongoā ki te hōtaka. Ka whakatikatikahia pea e rātou te wā o ngā inenga kei te heke mai, ka whakarerekē rānei i tō mahere rongoā kia mōhio ai koe kei te whiwhi tonu koe i te painga katoa o te rongoā.

Āhea Ka Taea e Au te Kati te Tango i te Bevacizumab-tnjn?

Me haere tonu koe ki te tango i te bevacizumab-tnjn mo te roa e taunaki ana to tohunga mate pukupuku, ahakoa ka pai ake koe. E mahi ana te rongoa ki te whakahaere i te tipu o te mate pukupuku, a, ko te whakamutu wawe rawa ka tere ake te ahunga whakamua o te mate pukupuku.

Ka whakatau to taakuta i te wa hei whakamutu i te maimoatanga i runga i te pai o te urupare o to mate pukupuku, ahakoa kei te pa ki a koe nga paanga kino nui, me to hauora whanui. Ka whakamahia e ratou nga karapa i nga wa katoa, nga whakamatautau toto, me nga whakamatautau tinana hei whakatau i tenei.

Ka taea e au te inu waipiro i te wa e tango ana i te Bevacizumab-tnjn?

Ko te inu waipiro i te wa e whiwhi ana i te bevacizumab-tnjn he pai tonu, engari he mea nui ki te korero ki to roopu hauora. Ka kaha ake pea te waipiro i etahi paanga kino penei i te toto tiketike, a ka raru pea te kaha o to tinana ki te whakaora.

Ka tohutohu pea to tohunga mate pukupuku ki te whakaiti i te inu waipiro, ina koa kei te pa ki a koe nga paanga kino penei i te toto tiketike, mena kei te whiwhi koe i etahi atu rongoa kaore e pai te whakakotahi me te waipiro. Ka taea e ratou te whakarato aratohu whaiaro i runga i to ahuatanga motuhake me te mahere maimoatanga whanui.