He aha te Cladribine: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

He rongoā whakahau a Cladribine e āwhina ana ki te rongoā i ētahi momo sclerosis maha mā te whakaiti i te mahi o ngā pūtau ārai mate e whakaeke ana i tō pūnaha io. He rongoā whāinga tēnei e mahi rerekē ana i te maha o ētahi atu rongoā MS, e tuku ana i te tūmanako mō ngā tāngata e pā ana ki ngā momo hoki mai o tēnei āhuatanga.

No tētahi rōpū rongoā tēnei rongoā e kīia nei ko te antimetabolites, ko te tikanga e pokanoa ana ki te tipu me te whakanui o ētahi pūtau. Ahakoa he mea āwangawanga tērā, he mea hoahoa mā te āta titiro a cladribine ki ngā pūtau ārai mate motuhake e whai wāhi ana ki ngā tohumate MS i te wā e waiho ana te nuinga o ō pūtau hauora anake.

He aha te Cladribine e whakamahia ana mō?

Ko te Cladribine te mea nui e whakamahia ana ki te rongoā i ngā momo hoki mai o te sclerosis maha i roto i ngā pakeke. Ka tohutohu pea tō tākuta i tēnei rongoā mēnā he MS hoki mai-whakawātea koe, he MS haere tonu tuarua rānei, kei reira ngā tohumate e haere mai ana, e haere ana i roto i ngā wāhanga.

Ka puta te sclerosis maha i te wā e whakaeke hē ana tō pūnaha ārai mate i te uhi whakamarumaru huri noa i ō muka io. Ka waihanga tēnei i te mumura me te kino ka puta ngā tohumate pēnei i te ngenge, ngā uaua haere, te ngongo, me ngā raruraru ki te whakatikatika. Ka āwhina a Cladribine mā te whakaiti i te maha o ngā lymphocytes, ko rātou ngā pūtau ārai mate motuhake e pā ana ki tēnei kino.

Ko te tikanga ka rahuitia te rongoā mō ngā tāngata he MS tino kaha, kāore rānei i pai te urupare ki ētahi atu rongoā. Ka āta arotake tō kaiwhakarato hauora i tō hītori rongoā me tō āhuatanga o nāianei kia whakatau mēnā ko te cladribine te kōwhiringa tika mōu.

Me pēhea te mahi a Cladribine?

Ka mahi a Cladribine mā te whāinga me te whakaiti i ngā momo pūtau toto mā e kīia nei ko lymphocytes, ina koa ko ngā pūtau B me ngā pūtau T e whai wāhi ana ki te mumura MS. Whakaarohia he ētita whiriwhiri e tango ana i ngā pūtau ārai mate raruraru i te wā e waiho ana te nuinga o tō pūnaha ārai mate.

Inā tangohia e koe te rongoā, ka huri ki tētahi āhua kaha i roto i ēnei pūtau whāinga. Ka raru tēnei āhua kaha i te kaha o ngā pūtau ki te whakanui me te ora, e arahi ana ki te whakahekenga nui engari he wā poto i roto i ngā pūtau ārai mate e whakaeke ana i tō pūnaha io.

E kiia ana he rongoā kaha tēnei i roto i te whānuitanga o te rongoā MS. He kaha ake i ētahi rongoā rārangi tuatahi engari i hangaia hei whakarato i ngā painga roa me ngā wā rongoā poto. Ka taea e ngā pānga te roa mō ngā marama, tau rānei i muri i te otinga o te akoranga rongoā.

Me pēhea taku tango i te Cladribine?

Ka tae mai te Cladribine hei papa e tangohia ana e koe mā te waha, te tikanga e whai ana i tētahi hōtaka motuhake i roto i ngā tau e rua. Ka whakarato tō tākuta i ngā tohutohu taipitopito, engari ko te tauira noa ko te tango i te rongoā mō ētahi rā i ngā wiki motuhake, me ngā wā whakatā roa i waenga.

Me tango e koe ngā papa cladribine i runga i te puku kau, kia kotahi haora i mua i te kai, kia rua haora rānei i muri i te kai. Horomia ngā papa katoa me te karaihe wai katoa, kaua e kuru, e ngaungau, e whati rānei. Ka āwhina tēnei ki te whakarite kia tika te ngongo o te rongoā me te mahi i te mea e tika ana.

He mea nui ki te whakahaere i ngā papa mā te āta, me te horoi i ō ringa i mua me muri i te tango. Ki te whati, ki te ngaro rānei tētahi papa, kaua e pā tika ki ngā wāhanga. Engari, whakamahia ngā karapu, tētahi rānei kakahu mākū hei horoi, i te mea ka taea te ngongo i te rongoā mā tō kiri.

Ka whakarite pea tō kaiwhakarato hauora i ngā whakamātautau toto i mua me te wā o te rongoā hei aroturuki i ō tatauranga pūtau toto mā me te hauora whānui. He mea nui ēnei whakaritenga mō te whakarite kia haumaru me te whai hua te mahi o te rongoā.

Kia Pēhea te Roa e Tango ai au i te Cladribine?

E rua tau te roa o te akoranga rongoā cladribine, engari e kore koe e tango rongoā tonu i roto i tēnei wā. Engari, ka whai wā rongoā motuhake koe, ka whai wā roa ka mutu te rongoā.

I te nuinga o te wā, ka tango koe i te cladribine mō te 4-5 rā i te marama tuatahi, ā, anō i te 4-5 rā i te marama tuarua o te tau tuatahi. E whai ana te tau tuarua i tētahi tauira rite, me ngā wā rongoā i ngā marama 13 me te 14. Whai muri i te whakaoti i tēnei akoranga e rua tau, he maha ngā tāngata kāore e hiahia rongoā cladribine atu mō ētahi tau.

Ko ngā wā roa i waenga i ngā wā rongoā ka āhei tō pūnaha ārai mate ki te ora, i te wā e mau tonu ana ngā pānga whakamarumaru o te rongoā ki ngā hokinga mai o te MS. Ka aroturuki tō tākuta i tō āhua i roto i tēnei wā, ka whakatau mēnā e hiahia ana koe i ētahi atu rongoā i te wā anō.

E hiahia ana ētahi tāngata ki te whakatika i tā rātou hōtaka rongoā i runga i ngā hua o te whakamātautau toto, i ētahi atu whakaaro hauora rānei. Ka mahi tō kaiwhakarato hauora ki a koe ki te kimi i te wā tika e haumaru ana, e whai hua ana mō tō āhuatanga motuhake.

He aha ngā pānga taha o te Cladribine?

Pērā i ngā rongoā katoa, ka taea e te cladribine te pānga taha, ahakoa he maha ngā tāngata e pai ana ki te tango. Ko ngā pānga taha tino noa he ngawari, he mārama hoki me te tautoko hauora tika.

Anei ngā pānga taha ka tino kitea e koe, me te mahara ka aroturuki tata tō rōpū hauora i a koe i roto i te rongoā:

• Ngā mate o te ara rārangi o runga pērā i te makariri, i ngā mate sinus rānei
• Ngā mamae o te upoko ka rereke mai i te ngawari ki te āhua
• Te whakaheke i ngā tatauranga pūtau toto mā, he wāhanga tēnei o te mahi a te rongoā
• Te whakapairuaki, te mamae puku rānei, ina koa i te tīmatanga o te rongoā
• Te ngenge, te ngenge rānei i te nuinga o te wā
• Te angiangi o ngā makawe, te ngaro rānei o ngā makawe mō te wā poto
• Te pānga kiri, te urupare kiri rānei

Ko te nuinga o ēnei pānga he wā poto noa iho, ka pai ake i te wā e urutau ana tō tinana ki te rongoā, i muri rānei i te otinga o te akoranga maimoatanga.

He tētahi atu o ngā pānga taha e tino nui ana, engari he iti noa iho te kitea, e hiahia ana kia āta tirohia e te tākuta. Ahakoa he onge ēnei, he mea nui kia mōhio koe ki a rātou kia taea ai e koe te rapu āwhina wawe ki te hiahiatia:

• Ngā mate kino nā te iti rawa o ngā pūtau toto mā
• Te toto rereke, te pānga rānei e kore e ora noa
• Te kirika tonu, ngā tohumate rānei pērā i te rewharewha
• Ngā pānga pāwera kino me te uaua ki te hā, te pūhi rānei
• Ngā tohu o ngā raruraru ate pērā i te kiri kōwhai, te mimi pouri rānei
• Te leukoencephalopathy multifocal haere tonu (PML), he mate roro onge

Ka whakahaere tō tākuta i ngā whakamātautau toto i ngā wā katoa kia kitea ai ngā huringa e pā ana ki te hauora i te wā wawe, ā, me whakapā atu koe ki a rātou tonu ki te pōturi koe i ngā tohumate e māharahara ana.

Ko wai kāore e tika kia tango Cladribine?

Kāore a Cladribine e tika ana mō te katoa, ā, ka āta arotake tō tākuta i tō hītori hauora i mua i te whakarite i te rongoā. E hiahia ana te rongoā ki tētahi pūnaha ārai mate kaha, e mahi ana, hei tīmatanga, nō reira ka kore e haumaru ētahi āhuatanga.

Kāore koe e tango cladribine ki te whai koe i ngā mate kaha, tae atu ki ngā mate tawhito pērā i te mate kohi, te hepatitis rānei. Me hauora tō pūnaha ārai mate i mua i te tīmatanga o te maimoatanga, i te mea ka whakaiti te rongoā i tō kaha ki te whawhai i ngā mate hou.

Ko te hunga whai mate tākihi, ate rānei, kāore i te nuinga o te wā e taea te tango cladribine i runga i te haumaru. Ka tukatukahia te rongoā mā ēnei okana, ā, ka taea e te mahi ngoikore te arahi ki te kohinga kino o te rongoā i roto i tō pūnaha.

He mea nui hoki te hapū me te whāngai u. Ka taea e te Cladribine te whara i ngā pēpi e tipu ana, nō reira me whakamahi koe i te aukati hapū whai hua i te wā o te rongoā me ngā marama maha i muri mai. Ki te whakamahere koe ki te hapū, kōrerohia ngā rongoā MS kē atu ki tō tākuta.

I tua atu, ki te whai hītori koe mō ētahi momo mate pukupuku, inā rā ngā mate pukupuku toto, me āta whakatau e tō tākuta ngā tūponotanga me ngā painga i mua i te tūtohu i te cladribine.

Ingoa Waitohu Cladribine

Ko te ingoa waitohu mō te cladribine waha ko Mavenclad, i hangaia e EMD Serono. Koinei te hanganga i whakaaetia mō te rongoā i te sclerosis maha, ā, ka tae mai i roto i ngā papa 10mg.

Ka rongo pea koe mō te cladribine e whakamahia ana i ētahi atu āhua mō ngā āhuatanga rerekē. Hei tauira, he āhua werohia e kīia ana ko Leustatin e whakamahia ana hei rongoā i ētahi mate pukupuku toto, engari he rongoā rerekē rawa tēnei ahakoa te tiritiri i te whakauru kaha kotahi.

I te wā e kōrero ana koe i tō rongoā ki ngā kaiwhakarato hauora, ki ngā kaimātai rongoā rānei, he mea whai hua ki te whakatakoto mai kei te tango koe i te Mavenclad mō te rongoā MS kia kore ai e raruraru ki ētahi atu hanganga cladribine.

Ngā Kōwhiringa Cladribine

Ki te kore te cladribine e tika ana mōu, he maha ētahi atu rongoā whai hua mō te MS e hoki mai ana ka whakaarohia e tō tākuta. Ka whakawhirinaki te kōwhiri ki ō tohu motuhake, te hītori hauora, me ngā whāinga rongoā.

Ko ētahi kōwhiringa ko te dimethyl fumarate (Tecfidera), e tangohia ana e rua i te rā, ā, ka mahi mā te whakaiti i te mumura i roto i te pūnaha io matua. Ko te Fingolimod (Gilenya) tētahi atu kōwhiringa e ārai ana i ngā pūtau ārai mate mai i te wehe atu i ngā pona lymph me te whakaeke i te roro me te taurakira.

Mō te hunga e kaha ana te MS, ka whakaarohia ētahi atu rongoā kaha pēnei i te natalizumab (Tysabri) rānei, ocrelizumab (Ocrevus). Ko ēnei ka hoatu i te nuinga o te wā hei whakawhiwhinga, kaua ki ngā pire o ia rā, he mea e pai ana ki ētahi tāngata.

He pai tonu nga rongoā werohia pēnei i te glatiramer acetate (Copaxone) me ngā whakaritenga interferon beta mō te nuinga o te tāngata, inā rā te hunga e pai ana ki ngā rongoā he roa te hītori haumaru.

Mā tō tākuta e āwhina i a koe ki te whakatau i ngā painga me ngā tūponotanga o ia kōwhiringa kia kitea te rongoā e pai ana ki tō oranga me ō hiahia hauora.

He Pai Anei te Cladribine i te Ocrelizumab?

He tino whai hua te cladribine me te ocrelizumab mō te MS e hoki mai ana, engari he rerekē te mahi me ngā painga rerekē. Ko te kōwhiringa

Ka taea te whakamahi i te Cladribine ki te hunga e mate ana i te ngakau, engari me tino aro turuki, me te whai whakaaro ki to ahuatanga ngakau. Kare te rongoa e pa tika ana ki te mahi o te ngakau, engari ka raru pea nga mate, etahi atu raruraru ranei i to hauora ngakau.

Me mahi tahi to tohunga ngakau me te tohunga roro kia mohio he haumaru te maimoatanga cladribine mo koe. Ka whakaarohia e ratou nga mea penei i o rongoa ngakau o naianei, te pumau o te ngakau, me te kaha ki te whawhai i nga mate ka raru pea to ngakau.

Mena he hitori o nga raruraru ngakau, kia mohio to tohunga MS me to tohunga ngakau ki o rongoa katoa me o ahuatanga hauora i mua i te tiimata i te maimoatanga cladribine.

Me aha ahau ki te tango pohehe au i te nui rawa o te Cladribine?

Mena ka tango pohehe koe i te nui atu o te cladribine i te mea i tohua, whakapā atu ki tō tākuta, ki te pokapū whakahaere paihana ranei i te wa tonu, ahakoa kei te pai koe. Ko te tango i te nui rawa ka arahi ki te heke kino o te tatauranga o ou pūtau toto ma, etahi atu raruraru nui ranei.

Kaua e ngana ki te whakapairuaki i a koe, ki te tango ranei i etahi atu rongoa mena kaore i tohutohuhia e te tohunga ngaio hauora. Kia mau ki te pounamu rongoa i a koe e rapu ana i te manaakitanga hauora kia kite nga kaiwhakarato i te mea me te nui i tangohia e koe.

Ka hiahia pea to taakuta ki te aro turuki i o tatauranga toto kia tata ake, a tera pea ka tūtohu i etahi atu manaaki tautoko i runga i te nui o te rongoa taapiri i tangohia e koe me te wa i pa ai.

Me aha ahau ki te ngaro au i te horopeta o Cladribine?

Mena ka ngaro koe i te horopeta o te cladribine, tangohia i te wa e mahara ana koe i te ra ano, i te mea kei roto tonu i te wa maimoatanga kua tohua. Heoi, kaua e tango e rua nga horopeta i te ra kotahi hei utu mo te horopeta i ngaro.

Mēnā ka mahara koe i te rā e whai ake nei, i muri mai rānei, waiho te horopeta i ngaro, ka haere tonu ki tō hōtaka auau. Kaua e ngana ki te whakanui i tō wā maimoatanga hei utu mō ngā horopeta i ngaro, nā te mea ka raru pea tēnei i te hōtaka maimoatanga kua whakaritea.

Whakapā atu ki tō kaiwhakarato hauora ki te kōrero mō te mea i tupu, me te tiki tohutohu motuhake mō tō āhuatanga. Ka hiahia pea rātou ki te whakatika i tō hōtaka aroturuki, ki te whakarato rānei i ētahi atu tohutohu i runga i te horopeta i ngaro i a koe, me te wā.

Āhea Āhau e mutu ai te tango Cladribine?

Kaua rawa koe e mutu te tango cladribine me te kore e kōrero tuatahi ki tō tākuta, ahakoa kei te pai ake koe, kei te pā rānei ētahi pānga taha. E whai ana te rongoā i tētahi mahere maimoatanga motuhake e rua tau te roa, i hangaia hei whakarato i ngā painga pai rawa atu i te wā e whakaiti ana i ngā tūponotanga.

Ko te nuinga o te tangata ka whakaoti i te akoranga e rua tau katoa i te mea i whakaritea, ā, i muri i tērā, kāore rātou e hiahia maimoatanga cladribine atu mō ētahi tau. Ka aroturukihia e tō tākuta tō āhuatanga, ka whakatau mēnā e hiahia ana koe i tētahi rongoā tiaki, i ētahi atu maimoatanga rānei i te wā e haere ake nei.

Mēnā kei te pā tētahi pānga taha e pā ana, ētahi atu raruraru rānei ki te rongoā, kōrerohia ēnei ki tō kaiwhakarato hauora, kaua ki te mutu anō. Ka āwhina rātou ki te whakahaere i ngā pānga taha, ki te whakatika rānei i tō mahere maimoatanga mēnā e tika ana.

Ka Taea e Āhau te Tiki Kānano i te wā e tango ana i te Cladribine?

He mea nui te wā o te kānano i te wā e tango ana i te cladribine, nā te mea ka pā te rongoā ki te kaha o tō pūnaha ārai mate ki te whakautu ki ngā kānano. Me karo katoa ngā kānano ora i te wā o te maimoatanga, me ētahi marama i muri mai.

Ka tūtohu tō tākuta ki te tiki i ngā kānano e hiahiatia ana i mua i te tīmatanga o te maimoatanga cladribine, i te wā e kaha tonu ana tō pūnaha ārai mate. Kei roto pea i tēnei ngā pūtu rewharewha, ngā kānano pneumonia, ngā kānano haere rānei mēnā kei te whakamahere koe i ngā haerenga.

Mēnā e hiahia ana koe ki ngā kano ārai mate i te wā o te rongoā, he pai ake te haumaru o ngā kano ārai mate kua whakakorengia i ngā mea ora, engari me arotake tō tākuta i ia āhuatanga takitahi. Ka whakaarohia e rātou ngā āhuatanga pēnei i ō tatauranga pūtau toto mā me te ohorere o te werohanga.