He aha te Colistimethate: Ngā Whakamahinga, te Inenga, Ngā Pānga Taha me Ētahi Atu

He paturopi kaha te Colistimethate e whakamahia ana e ngā tākuta i te wā kāore anō ētahi atu rongoā i whai hua ki ngā mate pāwera kino. No roto i tētahi rōpū rongoā e kīia ana ko te polymyxins, e kiia ana he paturopi "mutunga" mō ngā mate e mōrearea ana te ora i puta mai i ngā huakita e ātete ana ki te nuinga o ētahi atu rongoā.

Ka hāpai tēnei rongoā mā te werohanga, ki roto i te uaua, i te uaua rānei, nā te mea me mahi wawe, me te whai hua puta noa i tō tinana. Ahakoa he rongoā kaha e taea ana te whakaora i te ora, he tūponotanga ētahi e mātakitaki ana tō rōpū hauora.

He aha te Colistimethate e whakamahia ana?

Ka rongoā te Colistimethate i ngā mate kino i puta mai i ngā huakita gram-negative kāore e aro ana ki ētahi atu paturopi. Ka tohutohu tō tākuta i tēnei rongoā i te wā e pā ana koe i tētahi mate kino, kāore anō ētahi atu rongoā i whai hua.

Ko ngā mate e tino rongoā ana ki te colistimethate ko te pneumonia, ngā mate i roto i te toto, ngā mate i roto i te ara mimi, me ngā mate kiri. He tino whai hua ki ngā huakita pēnei i te Pseudomonas aeruginosa, Acinetobacter, me ētahi momo E. coli kua ātete ki te maha o ngā paturopi.

I ētahi wā ka whakamahia hoki e ngā tākuta te colistimethate hei ārai i ngā mate i roto i ngā tāngata e tino mōrearea ana, pēnei i te hunga e mate ana i te cystic fibrosis, i ngā tūroro rānei i roto i ngā wae tiaki kaha. Heoi, he iti ake te whakamahi ārai i tēnei, me te whai whakaaro nui ki ngā painga me ngā tūponotanga.

Me pēhea te mahi a te Colistimethate?

Ka mahi te Colistimethate mā te whakaeke i te pakitara o waho o ngā pūtau huakita, e pā ana ki te pakaru me te mate. Whakaarohia me te wero i ngā rua ki roto i te pōro - ka pakaru te pakitara pūtau huakita, kāore e ora te huakita.

He paturopi kaha tēnei i hangaia hei whawhai i ngā huakita kua whai parenga ki ētahi atu rongoā. Koinei te mea e kīia ana e ngā tākuta he paturopi "bactericidal", arā, ka patu kē i ngā huakita, kaua ki te aukati i tō rātou tipu.

Ka huri te rongoā ki tōna āhua kaha e kīia ana ko te colistin i te wā e uru ana ki tō tinana. Mā tēnei huringa e whakaiti ētahi o ngā pānga taha, me te pupuri tonu i ngā pānga antibacterial kaha o te rongoā.

Me pēhea taku tango i te Colistimethate?

Ka whiwhi koe i te colistimethate hei werohanga i roto i te hōhipera, i te wāhi haumanu rānei, kaua rawa hei pire ka tango koe i te kāinga. Ka tukuna te rongoā mā te raina IV ki tō uaua, mā te werohanga rānei ki tō uaua, i runga i tō āhuatanga motuhake.

Ka tātai tō rōpū hauora i tō horopeta tika i runga i tō taumaha, te mahi o tō pūkahukahu, me te kaha o tō mate. Ko te maimoatanga noa ko te whiwhi i te rongoā 2-4 ngā wā ia rā, me te horopeta katoa e tukuna ana i te wā roa i roto i te 30 meneti ki te 2 hāora mēnā mā te IV.

Kāore koe e hiahia ki te māharahara mō te tango i tēnei rongoā me te kai i te mea ka tukuna hei werohanga. Heoi, he mea nui kia noho pai te wai i te wā o te maimoatanga, nā reira inu nui i te wai ki te kore te tākuta e kī atu ki a koe.

Ka mātakitaki tata tō rōpū hauora i a koe i te wā o te maimoatanga, me te tirotiro i tō toto i ngā wā katoa kia mōhio kei te pai te mahi o te rongoā, ā, kāore e pā mai ngā pānga taha kino.

Kia pēhea te roa e tango ai au i te Colistimethate?

Ko te roa o te maimoatanga me te colistimethate te tikanga mai i te 7 ki te 14 rā, engari ka rerekē tēnei i runga i tō mate motuhake me te pēhea tō urupare ki te maimoatanga. Mā tō tākuta e whakatau te roa tika i runga i ētahi āhuatanga.

Mō te nuinga o ngā mate pāwera huakita, me haere tonu te rongoā kia kitea e ngā whakamātau taiwhanga kua ngaro ngā huakita, ā, kua pai ake ō tohu. Ko ētahi mate kino rawa pea ka roa ake te rongoā, ēngari ko ētahi ka tere ake te whakautu.

Ka aroturukihia tō haere e tō rōpū hauora mā ngā whakamātau toto auau, ngā rangahau whakaahua, me ngā whakamātau tinana. Ka mātakitaki hoki rātou mō ngā tohu e ngaro ana te mate, pēnei i te heke o te kirika, te pai ake o te manawa, te rānei i te rongoā o ngā patunga kua pangia.

He mea nui kia whakaoti i te rongoā katoa ahakoa ka tīmata koe ki te pai ake. Ko te whakamutu wawe rawa ka taea e ngā huakita te hoki mai me te kaha ake, me te ātete ki te rongoā.

He aha ngā pānga taha o te Colistimethate?

Pērā i ngā rongoā kaha katoa, ka taea e te colistimethate te pānga taha, ahakoa kāore te katoa e pā ana ki a rātou. Ko ngā pānga taha tino noa he mea whakahaere, ā, ka mātakitaki tō rōpū hauora i a rātou.

Anei ngā pānga taha ka pā ki a koe, ka tīmata mai i ngā mea tino noa:

• Ngā raruraru tākihi, tae atu ki ngā huringa i te mimi, te pūhi rānei i ō waewae, ō waewae rānei
• Te whanoke, te kore rānei e tū tika, ina koa ka tū ake
• Te ngau rānei, te ngaro rānei o te rongo i ō ringa, ō waewae, i te waha rānei
• Te whakapairuaki, te puku rānei
• Te mamae, te riri rānei i te wāhi werohanga
• Te ānini, te pōraruraru rānei
• Te ngoikoretanga o te uaua, te uaua rānei ki te whakatikatika

Ko te nuinga o ēnei pānga he ngawari, he wā poto, engari ka aroturukihia koe e tō rōpū hauora kia kitea wawe ngā raruraru. Ka tirohia e rātou tō mahi tākihi me ngā urupare io i te wā o te rongoā.

Ko ētahi pānga taha onge engari he kino, tae atu ki te kino nui o te tākihi, ngā raruraru manawa, ngā huringa nui rānei i tō āhua hinengaro. Kua whakangungua tō rōpū hauora ki te mōhio ki ēnei tohu, ā, ka mahi tonu rātou ki te puta mai.

Ko wai kāore e tika kia tango Colistimethate?

Kāore te colistimethate e tika ana mō te katoa, ā, ka āta tātari tō tākuta i tō hītori hauora i mua i te whakahau. Ko ngā tāngata e pā ana ki ētahi āhuatanga hauora ka hiahia pea ki ētahi atu rongoā, ki te aroturuki motuhake rānei.

Kāore koe e whiwhi colistimethate mēnā he pānga koe ki te colistin, ki ngā paturopi polymyxin, ki ētahi atu kai rānei kei roto i te rongoā. Kōrero atu ki tō rōpū hauora mō ngā pānga pānga ki ngā paturopi i mua, ahakoa kāore e whai pānga ana.

Ko ngā tāngata e pā ana ki ngā raruraru tākihi e hiahia ana ki te whakaaro motuhake, nā te mea ka pā te colistimethate ki te mahi tākihi. Ka whakataurite tō tākuta i ngā painga ki ngā tūponotanga, ā, ka whakatika pea i tō horopeta, ka kōwhiri rānei i tētahi atu rongoā mēnā kāore i te pai te mahi o ō tākihi.

Mēnā he myasthenia gravis koe (he āhuatanga ngoikore uaua), he raruraru io, he raruraru rongo rānei, me āta aroturuki koe e tō tākuta. Ka taea te whakakaha i ēnei āhuatanga e te colistimethate, ahakoa me whai rongoā tonu koe mēnā he mate kino tō.

E hiahia ana ngā wāhine hapū me te whāngai u ki te whakaaro motuhake, nā te mea he iti noa ngā kōrero mō te haumaru o te colistimethate i te wā e hapū ana. Ka whakahau tō tākuta i te rongoā mēnā ka nui ake ngā painga i ngā tūponotanga.

Ngā Ingoa Waitohu Colistimethate

Kei te wātea te Colistimethate i raro i ētahi ingoa waitohu, ko Coly-Mycin M tētahi o ngā mea tino noa i te United States. Ko ētahi atu ingoa waitohu ko Colistin me Promixin, ahakoa he rerekē te wātea i ia whenua.

Ko te ingoa whānui

Ki te kore e tika, e wātea rānei te colistimethate, ka whakaaro pea tō tākuta ki ētahi atu paturopi, ahakoa he iti noa ngā kōwhiringa mō ngā huakita ātete. Ka whakawhirinaki te kōwhiringa ki ngā huakita e pā ana ki tō mate me tō rātou tairongo ki ngā rongoā rerekē.

Ko ētahi atu kōwhiringa ko te tigecycline, e whawhai ana ki te maha o ngā huakita ātete, me ngā rongoā whakakotahi e whakamahi ana i te maha o ngā paturopi. Ko ngā rongoā hou pēnei i te ceftazidime-avibactam, i te meropenem-vaborbactam rānei, he kōwhiringa pea mō ētahi momo mate.

I ētahi wā, ka whakamātau pea tō tākuta i te polymyxin B, he tino whanaunga ki te colistimethate, ā, he rite te mahi. Heoi, he rite tonu ngā pānga taha, nō reira ehara tēnei i te kōwhiringa pai mēnā i raru koe i te colistimethate.

Ko te mea pono, mō te maha o ngā mate tino ātete, ko te colistimethate tonu tētahi o ngā rongoā whai hua e wātea ana. Ka ngana tonu tō rōpū hauora ki te kimi i te kōwhiringa haumaru me te whai hua mō tō āhuatanga motuhake.

He Pai Anei te Colistimethate i Ētahi Atu Paturopi?

Kāore i te tika te colistimethate i te

Ka ngana tonu tō tākuta ki te whakamahi i te paturopi ngawari whai hua i te tuatahi, ka neke ki ngā kōwhiringa kaha ake pēnei i te colistimethate ina tika ana. Mā tēnei huarahi e tiaki te whai huatanga o ēnei rongoā kaha mō te wā e tino hiahiatia ana.

Ngā Pātai Auau mō Colistimethate

He Haumaru te Colistimethate mō te hunga e mate ana i te mate tākihi?

Ka pā te Colistimethate ki te mahi tākihi, nō reira me mātua tiaki me te aroturuki i te hunga e raru ana i te tākihi. Ka whakatika tō tākuta i tō inenga i runga i te pai o te mahi o ō tākihi, ā, ka tirohia te mahi o ō tākihi i ngā wā katoa i te wā o te rongoā.

Mēnā he raru ngawari ō tākihi, ka taea tonu pea e koe te whiwhi colistimethate me te inenga whakaheke me te aroturuki anō. Heoi, mēnā kua tino pāngia te mahi o ō tākihi, tērā pea me whakaaro tō tākuta ki ētahi atu rongoā, ki te whakamahi rānei i te colistimethate ina tino tika ana.

Me pēhea ahau ki te pā mai ngā pānga taha kino?

I te mea ka whiwhi koe i te colistimethate i roto i te hōhipera, i te wāhi haumanu rānei, ka aroturukihia koe e tō rōpū hauora mō ngā pānga taha. Mēnā ka kite koe i ētahi tohu e pā ana ki a koe pēnei i te uaua ki te manawa, te whanoke nui, te huringa nui rānei i te mimi, kōrero tonu ki tō nēhi, ki tō tākuta rānei.

Kaua e māharahara ki te whakararuraru i ngā kaimahi hauora - e hiahia ana rātou ki te mōhio mō ngā tohu e pā ana ki a koe. Mā te kite wawe me te rongoā i ngā pānga taha ka ārai i ngā raru nui ake mai i te whanake.

He aha te mea ka pā mai ki te ngaro i ahau tētahi inenga o Colistimethate?

I te mea ka tukuna te colistimethate e ngā tohunga hauora i roto i te wāhi rongoā, kāore koe e mōhio ki te ngaro i ngā inenga. Mā tō rōpū hauora e whakarite kia whiwhi koe i tō rongoā i runga i te wā i te wāhanga o tō mahere rongoā.

Mena he take ka whakawhāia te horopeta i ngā tikanga rongoā, i ētahi atu rānei rongoā, ka whakatika tō rōpū hauora i te wā tika. Mā rātou e whakarite kia whiwhi koe i te akoranga rongoā katoa e hiahiatia ana mō tō mate.

Āhea ka taea e au te whakamutu i te tango Colistimethate?

Kaua rawa koe e whakamutu i te rongoā colistimethate i runga i tō ake - me whakatau tonu tēnei whakatau e tō rōpū hauora i runga i tō urupare ki te rongoā me ngā hua whakamātautau. Ko te whakamutu wawe rawa ka taea e te mate te hoki mai i te kaha ake i mua.

Ka whakatau tō tākuta i te wā hei whakamutu i te rongoā i runga i ētahi mea: te pai ake o ō tohu, ngā whakamātautau toto e whakaatu ana kei te ngaro te mate, me te whakarite kua whiwhi koe i te rongoā nui hei aukati i te hokinga mai o te huakita.

Ka taea e Colistimethate te pāhekoheko ki ētahi atu rongoā?

Āe, ka taea e colistimethate te pāhekoheko ki ētahi atu rongoā, koinei te take ka arotake tō rōpū hauora i ō rongoā katoa o nāianei i mua i te tīmatanga o te rongoā. Ko ngā pāhekoheko tino nui ko ētahi atu rongoā ka pā ki ngā whatukuhu, ki te pūnaha io rānei.

Ko ngā rongoā pēnei i ngā paturopi aminoglycoside, ētahi diuretics, me ētahi rongoā mamae ka piki ake te tūponotanga o ngā raruraru whatukuhu ina honoa ki te colistimethate. Ka āta whakahaere tō rōpū hauora i ēnei pāhekoheko, ā, ka whakatika pea i ngā horopeta, i te wā rānei o ētahi atu rongoā i te mea e tika ana.