Eculizumab (ara huarahi intravenous)

Bkemv, Epysqli, Soliris

Ko te werohanga Eculizumab te whakamahi hei whakaora i tetahi momo mate toto e kiia nei ko te paroxysmal nocturnal hemoglobinuria (PNH). Ko tenei rongoā hei whakaiti i te whakangaromanga o ngā pūtau toto whero, te pakaru rānei (hemolysis) i ngā tūmanako e pangia ana e te PNH. Ka whakamahia hoki tenei rongoā hei whakaora i te mate whatukuhu kino e kiia nei ko te atypical hemolytic uremic syndrome (aHUS). Ka whakamahia ano te werohanga Eculizumab hei whakaora i te mate ngakau me te uaua e kiia nei ko te generalized myasthenia gravis (gMG) i ngā tūmanako e pai ana te anti-acetylcholine receptor (AchR) antibody. Ka whakamahia ano te werohanga Eculizumab hei whakaora i te mate neuromyelitis optica spectrum disorder (NMOSD), he mate onge e pā ana ki te mumura o ngā uaua o ngā kanohi me te iwi o muri. Ka whakamahia i ngā tūmanako e pai ana te anti-aquaporin-4 (AQP4) antibody. Ko te werohanga Eculizumab he monoclonal antibody e mahi ana i runga i te pūnaha mate. Kei te wātea noa tenei rongoā i raro i te kaupapa tohatoha whakawāiti e kiia nei ko Ultomiris® me te Soliris® REMS (Risk Evaluation and Mitigation Strategy) Program. Kei te wātea tenei hua i ngā momo horoinga e whai ake nei:

I te whakatau ki te whakamahi i te rongoā, me whakarite te kino o te tango i te rongoā ki te pai ka mahia. Ko tēnei he whakatau ka mahia e koe me tō tākuta. Mō tēnei rongoā, me whakaarohia enei: Korero atu ki tō tākuta mēnā kua pāngia koe e tetahi āhuatanga rerekē, te mate pāwera rānei ki tēnei rongoā, ki ētahi atu rongoā rānei. Korero atu hoki ki tō kaimahi hauora mēnā kei a koe ētahi atu momo mate pāwera, pēnei i ngā kai, ngā tae, ngā whakaora, ngā kararehe rānei. Mō ngā hua kore-whakahaunga, panuihia te tohu, te whakauru rānei o te kete. Ko ngā rangahau tika kua oti i tēnei wā kāhore i whakaatu i ngā raruraru motuhake mo ngā tamariki ka āhei te whakaiti i te whakamahinga o te werohanga eculizumab hei whakaora i te mate hemolytic uremic syndrome koretake i ngā tamariki. Heoi, kāhore i whakatūria te ora me te whai hua o te werohanga eculizumab hei whakaora i ētahi atu āhuatanga i ngā tamariki. Ko ngā rangahau tika kua oti i tēnei wā kāhore i whakaatu i ngā raruraru motuhake mō ngā kaumātua ka āhei te whakaiti i te whakamahinga o te werohanga eculizumab i ngā kaumātua. Kāhore he rangahau tika i ngā wāhine hei whakatau i te tūponotanga o te pēpi ina whakamahi i tēnei rongoā i te wā e whāngai u. Whakaritea ngā painga pea ki ngā tūponotanga pea i mua i te tango i tēnei rongoā i te wā e whāngai u ana. Ahakoa kāhore e tika te whakamahi tahi i ētahi rongoā, i ētahi atu take ka taea te whakamahi tahi i ngā rongoā rerekē e rua ahakoa ka puta pea he mahi tahi. I enei take, ka hiahia pea tō tākuta ki te whakarereke i te rongoā, te whakamahi rānei i ētahi atu whakatūpato. I te wā e whiwhi ana koe i tēnei rongoā, he mea nui rawa kia mohio tō kaimahi hauora mēnā kei te tango koe i tetahi o ngā rongoā kei raro nei. Kua tohua ngā mahi tahi e whai ake nei i runga i te nui o te āhuatanga, ā, ehara i te mea katoa. Ko te whakamahi i tēnei rongoā me tetahi o ngā rongoā e whai ake nei kāhore e tūtohutia, engari ka hiahiatia pea i ētahi wā. Mena ka tohua ngā rongoā e rua tahi, ka whakarereke pea tō tākuta i te rongoā, te auau rānei o te whakamahinga o tetahi, o ngā rongoā rānei e rua. Kāhore e tika te whakamahi i ētahi rongoā i te wā e kai ana, i te taha rānei o te kai, te kai rānei i ētahi momo kai, nā te mea ka puta pea he mahi tahi. Ko te whakamahi i te waipiro, te tapeka rānei me ētahi rongoā ka puta pea he mahi tahi. Kōrero atu ki tō kaimahi hauora te whakamahinga o tō rongoā me te kai, te waipiro, te tapeka rānei. Ko te whai i ētahi atu raruraru hauora ka pā pea ki te whakamahinga o tēnei rongoā. Kia tino kī atu koe ki tō tākuta mēnā kei a koe ētahi atu raruraru hauora, ina koa: