He aha te Glasdegib: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

He rongoā mate pukupuku a Glasdegib e whai ana ki te āwhina i ētahi momo mate pukupuku toto, ina koa te leukemia myeloid acute (AML). E mahi ana tēnei rongoā waha mā te aukati i ngā pūmua motuhake e hiahia ana ngā pūtau mate pukupuku ki te tipu me te ora, e whai wāhi ana tō pūnaha ārai mate ki te whawhai i te mate.

Mēnā kua tohua a Glasdegib ki a koe, ki tētahi rānei e manaaki ana koe, he maha pea āu pātai mō te āhua o tana mahi, te aha e tūmanakohia ana, me te āhua o te tango i te rongoā i runga i te haumaru. Me haere tātou i ngā mea katoa e hiahia ana koe ki te mōhio mō tēnei rongoā nui i roto i ngā kupu māmā, mārama.

He aha te Glasdegib?

He rongoā mate pukupuku a Glasdegib e tohua ana e te tākuta, e noho ana ki tētahi rōpū rongoā e kīia ana ko ngā aukati ara hedgehog. I hangaia motuhake hei rongoā i te leukemia myeloid acute (AML), tētahi momo mate pukupuku toto e pā ana ki tō wheua wheua me ngā pūtau toto.

Ka tae mai te rongoā i roto i ngā papa waha e tango ana koe mā te waha, e māmā ake ai te rongoā i ngā rongoā mate pukupuku maha e hiahia ana ki ngā haerenga hōhipera. E mahi ana a Glasdegib mā te whai me te aukati i tētahi ara pūtau motuhake e whakamahia ana e ngā pūtau mate pukupuku ki te tipu me te whakaputa uri.

Ka tohua e tō tākuta a Glasdegib i te nuinga o te wā i te taha o tētahi atu rongoā haumanu e kīia ana ko te cytarabine. E āwhina ana tēnei huarahi whakakotahi i te whawhai i te mate pukupuku mai i ngā koki maha, e pai ake ai ō hua rongoā.

He aha te Glasdegib e whakamahia ana?

Ka whakamahia te Glasdegib ki te rongoā i te leukemia myeloid acute (AML) i roto i ngā pakeke 75 tau, neke atu rānei, i te hunga rānei he āhua hauora kē atu e kore ai e tika mō te rongoā haumanu kaha. E āwhina ana tēnei huarahi whai i te hunga kāore pea i te kaha mō ngā rongoā mate pukupuku tuku iho, kaha ake.

Kua whakaaetia te rongoa mo nga turoro AML katahi ano ka kitea. He mate pukupuku tere te AML e pa ana ki te toto me te wheua wheua, kei reira to tinana e hanga ana i nga pūtau toto hou. Ki te kore he rongoa, ka mate pea tenei momo leukemia.

Ka whakaaro pea to tohunga mate pukupuku ki te glasdegib mena kei a koe etahi tohu ira i roto i o pūtau mate pukupuku e kii ana ka whai hua tenei rongoa mo to momo AML. Ka awhina nga whakamatautau toto me nga koiora wheua wheua ki te whakatau mena ko te glasdegib te whiringa tika mo to mahere maimoatanga.

Me pehea te mahi a Glasdegib?

Ka mahi a Glasdegib ma te aukati i tetahi ara whakawhitiwhiti korero pūtau e kiia nei ko te ara hedgehog. Whakaarohia tenei ara he huinga tohu e korero ana ki nga pūtau me pehea te tipu me te wehe. I roto i te maha o nga mate pukupuku, tae atu ki te AML, ka piri enei tohu ki te tuunga

Horomia ngā papa katoa me te karaihe wai. Kaua e kuru, e ngaungau, e whati rānei ngā papa, nā te mea ka pā tēnei ki te āhua o te rongoā e uru ana, ā, ka puta pea ngā pānga kino. Mēnā he uaua ki a koe te horomia i ngā pire, kōrero ki tō tākuta mō ētahi atu kōwhiringa.

He pai ake te tango i te glasdegib i te wā e taea ai e koe te rite i ia rā. He maha ngā tāngata e kite ana he āwhina ki te tango i te parakuihi, i te tina rānei kia waihanga i tētahi wāhanga o ā rātou mahi o ia rā. Kāore ngā mea kei roto i tō puku e pā nui ana ki te āhua o te mahi a te rongoā, nō reira ka taea e koe te whiriwhiri i te mea e pai ana ki a koe.

Kia Pēhea te Roa e Tango Ana ahau i te Glasdegib?

Ko te roa o tō maimoatanga glasdegib e whakawhirinaki ana ki te pai o te mahi a te rongoā me te āhua o tō whakamanawanui. Ko te nuinga o ngā tāngata e tango ana i te glasdegib mō ētahi marama, ā, me haere tonu ētahi ki te maimoatanga mō te tau, neke atu rānei.

Ka aroturukihia e tō tākuta ō tatauranga toto me te hauora whānui i ngā wā katoa hei whakatau mēnā kei te āwhina te rongoā ki te whawhai i tō mate pukupuku. Ko ēnei arowhai ka puta i ia wiki, i ia wiki ruarua rānei i te tīmatanga, ā, ka iti ake te auau i te wa e haere ana tō maimoatanga.

Kaua rawa e mutu te tango i te glasdegib me te kore e kōrero tuatahi ki tō tākuta, ahakoa kei te pai ake koe. He pai ake te mahi a ngā maimoatanga mate pukupuku ina tangohia ana i te wā katoa, ā, ko te whakamutu wawe rawa ka taea e te mate pukupuku te hoki mai, te kino ake rānei. Mā tō rōpū hauora koe e whakamōhio mō te wā e haumaru ana ki te mutu, mēnā rānei me haere tonu koe i te maimoatanga.

He Aha ngā Pānga Kino o te Glasdegib?

Pērā i ngā rongoā mate pukupuku katoa, ka taea e te glasdegib te pānga kino, ahakoa kāore te katoa e pā ana ki a rātou. Ko te nuinga o ngā pānga kino ka taea te whakahaere mā te manaaki tika me te aroturuki mai i tō rōpū hauora.

Koinei ngā pānga kino e pā ana ki a koe i te wā e tango ana koe i te glasdegib:

• Te ngenge me te ngoikore
• Te whakapairuaki me te kore hiahia
• Ngā uaua e kōpiko ana, e pāngia ana rānei
• Ngā huringa o te reka
• Te korere, te pāpā rānei
• Te pūhi i ngā ringa, ngā waewae, ngā waewae rānei
• Te poto o te manawa

Ko ēnei pānga taha noa ka pai ake i te wā e urutau ana tō tinana ki te rongoā. Ka taea e tō tākuta te kōrero i ngā huarahi hei whakahaere i a rātou, pēnei i ngā rongoā anti-nausea, i ngā huringa kai rānei.

Ka pā pea ki ētahi tāngata ngā pānga taha nui ake engari he iti noa iho te pānga e hiahia ana kia āta tirohia e te tākuta:

• Ngā raruraru o te manawa (te manawa kōaro, te mamae o te uma)
• Te ngoikore nui o ngā uaua, te mamae rānei
• Ngā tohu o te mate (te kirika, te mākākā, te mare tonu)
• Te rere toto, te pā rānei e kore e rite
• Te korere nui, te ruaki rānei
• Te uaua ki te hā, te piri rānei o te uma

Whakapā atu ki tō kaiwhakarato hauora i te wā tonu mēnā ka pā ki a koe ētahi o ēnei pānga taha nui. Ka taea e rātou te whakatika i tō mahere maimoatanga, te whakarato rānei i ētahi atu rongoā hei āwhina i te whakahaere i ēnei tohu i runga i te haumaru.

Ko wai kāore e tika kia tango Glasdegib?

Kāore a Glasdegib e tika ana mō te katoa, ā, ka āta arotake tō tākuta i tō hītori hauora i mua i te whakarite. Ko ētahi āhuatanga hauora me ngā rongoā ka kore e haumaru, ka iti ake rānei te whai hua o te glasdegib.

Kāore koe e tango glasdegib mēnā kei te hapū koe, kei te whakamahere rānei koe kia hapū. Ka taea e te rongoā te whakaputa i ngā hē whānau nui, me te whara i ngā pēpi kāore anō kia whānau. Me whakamahi ngā tāne me ngā wāhine i te mana whakawhānau whai hua i te wā o te maimoatanga, me ngā marama maha i muri i te whakamutu i te rongoā.

Ka tūpato rawa tō tākuta ki te whakarite glasdegib mēnā he:

• Ngā raruraru o te manawa, te mate manawa rānei
• Te mate ate, te mate tākihi rānei
• He hītori o ngā mate uaua
• Ngā tatauranga pūtau toto iti
• Ngā mate kaha

Ka taea e ētahi rongoā te pānga ki te glasdegib, ka nui ake, ka iti ake rānei te whai hua. Me kōrero tonu ki tō tākuta mō ngā rongoā katoa, ngā tāpiringa, me ngā hua otaota e inu ana koe i mua i te tīmatanga o te rongoā glasdegib.

Ingoa Waitohu Glasdegib

Ka hokona te Glasdegib i raro i te ingoa waitohu Daurismo. Koinei anake te ingoa waitohu e wātea ana i tēnei wā mō tēnei rongoā, he rongoā mate pukupuku hou, he rongoā motuhake.

I te wā e tiki ana koe i tō rongoā, ka kite koe i te

E whakaatu ana te rangahau he pai ake te glasdegib i te tahi me te cytarabine iti-rahinga i te cytarabine anake mō te rongoā AML i roto i ngā pakeke, i te hunga rānei e kore e taea te rongoā kaha. Ka āwhina te huarahi whakakotahi ki te whakaeke i ngā pūtau mate pukupuku mā ngā tikanga maha.

I kitea e ngā rangahau he roa ake te ora o te hunga e tango ana i te glasdegib me te cytarabine i te hunga e tango ana i te cytarabine anake. I whakaatu hoki te whakakotahitanga i ngā reiti whakautu pai ake, ko te tikanga he nui ake te hunga i kite i te whakautu o tā rātou mate pukupuku ki te rongoā.

Heoi, ka tae mai te whakakotahitanga me ngā pānga taha atu i te cytarabine anake. Ka whakataurite tō tākuta i ngā painga pea ki ngā tūponotanga i runga i tō āhuatanga hauora takitahi. Ko te whāinga i ngā wā katoa ko te kimi i te rongoā e whai wāhi ana koe ki te whawhai i tō mate pukupuku i te wā e pupuri ana i tō kounga o te ora.

Ngā Pātai Auau mō Glasdegib

Q1. He Haumaru a Glasdegib mō te Hunga e Pā ana ki ngā Raru o te Ngākau?

Ka pā te Glasdegib ki te manawataki o te ngākau, nō reira ka āta arotake tō tākuta i tō hauora ngākau i mua i te whakahau. Mēnā he raru ngākau tō, ka hiahia koe ki te aroturuki atu i te wā o te rongoā, tae atu ki ngā electrocardiograms (EKGs) auau hei tirotiro i tō manawataki ngākau.

Ka mahi tahi tō kaimātai ngākau me te tohunga mate pukupuku ki te whakatau mēnā he haumaru a glasdegib mōu. Ka whakatika pea rātou i tō inenga, ka tūtohu rānei i ngā rongoā ngākau atu hei pupuri i a koe i te wā o te rongoā mate pukupuku. Kaua rawa e whakaroa ki te pūrongo i te mamae o te uma, te manawataki ngākau koretake, te poto rānei o te manawa ki tō rōpū hauora.

Q2. Me Pēhea Taku Mahi Mēnā Ka Tango Ahau i te Nui Rawa o Glasdegib?

Mēnā ka tango koe i te nui rawa o te glasdegib i te mea kua whakahaua, whakapā atu ki tō tākuta, ki te pokapū whakahaere paitini rānei i te wā tonu. Kaua e tatari kia kite mēnā ka pāngia koe, i te mea he pai ake te wawaotanga wawe ki ngā horopeta rongoā nui.

Mena ka nui rawa te glasdegib ka nui ake pea te tūponotanga o ngā pānga kino, ina koa ko ngā raruraru o te manawa, te ngoikore rānei o ngā uaua. Puritia te pounamu rongoā ki a koe ina waea ana koe kia taea ai e koe te tuku pārongo tika mō te nui o te rongoā i tangohia e koe, me te wā.

Q3. Me Pēhea Taku Mahi Mēnā Kua Ngaro i Ahau tētahi Inenga o Glasdegib?

Mēnā kua ngaro i a koe tētahi inenga o glasdegib, tangohia tonu i te wā e mahara ana koe, ki te kore e tata ana te wā mō tō inenga e whai ake nei. I tērā wā, waiho te inenga i ngaro, ka haere tonu ki tō hōtaka auau. Kaua rawa e tango e rua ngā inenga i te wā kotahi hei utu mō tētahi inenga i ngaro.

Whakamātau ki te tango i tō inenga i ngaro i roto i ngā hāora 12 mai i te wā e tango ana koe. Mēnā kua pahure i te 12 hāora, he pai ake te tatari kia tae rawa ki tō inenga e whai ake nei. Whakapā atu ki tō rōpū hauora mēnā kāore koe i te mōhio ki te wā, mēnā rānei kua ngaro i a koe te maha o ngā inenga.

Q4. Āhea Āhau e Kati ai te Tango i te Glasdegib?

Kati anake te tango i te glasdegib ina kī mai tō tākuta he haumaru te mahi. Ka aroturukihia e tō rōpū hauora ō toto me te urupare whānui ki te rongoā hei whakatau i te wā pai ki te whakamutu, ki te huri rānei i tō rongoā.

Ko ētahi tāngata ka hiahia ki te haere tonu i te glasdegib mō te maha o ngā marama, tau rānei, i runga i te pai o tōna mahi me te pēhea o te whakahaere. Ko ētahi atu ka mutu wawe mēnā ka eke rātou ki te murunga hara, mēnā rānei ka uaua rawa ngā pānga kino ki te whakahaere. He mea whaiaro tō mahere rongoā ki tō āhuatanga motuhake.

Q5. Ka Taea e Āhau te Tango i te Glasdegib me Ētahi Atu Rongoā?

He maha ngā rongoā ka taea te pā ki te glasdegib, nō reira he mea nui ki te kōrero ki tō tākuta mō ngā mea katoa e tango ana koe, tae atu ki ngā rongoā kore-whakahaunga, ngā tāpiringa, me ngā hua otaota. Ko ētahi rongoā ka taea te whakaiti i te whai huatanga o te glasdegib, ka nui ake rānei te tūponotanga o ngā pānga kino.

Ka arotakehia e tō tākuta ngā rongoā katoa e whakamahia ana e koe i mua i te tīmatanga o te glasdegib, ā, tērā pea ka whakatika i ngā inenga, ka huri rānei i ētahi rongoā kē atu. Ka mātakitaki hoki rātou i a koe i te wā e whakamahi ana koe i ngā rongoā e pā ana ki te glasdegib. Me kōrero tonu ki tō rōpū hauora i mua i te tīmatanga o ngā rongoā hou i te wā e whakamahi ana koe i te glasdegib.