He aha te Hydroxychloroquine: Ngā Whakamahinga, te Inenga, Ngā Pānga Taha me Ētahi Atu

Ko te Hydroxychloroquine he rongoā rongoā e whakamahia ana e ngā tākuta hei rongoā i te malaria, te rūmātiki, me te lupus. Ka mōhiotia pea e koe i tōna ingoa waitohu, Plaquenil, ā, nō te rōpū rongoā e kīia nei ko ngā antimalarials e mahi ana mā te whakaiti i te mumura i tō tinana.

Kua whakamahia pai tēnei rongoā mō ngā tekau tau hei āwhina i te tangata ki te whakahaere i ngā āhuatanga autoimmune mau tonu. Ahakoa i puta i ngā pane rongoā i te wā o te mate urutā COVID-19, ko tōna tūranga tuatahi ko te āwhina i te tangata ki te rūmātiki me te lupus kia ora ake ai.

He aha te Hydroxychloroquine?

Ko te Hydroxychloroquine he rongoā antimalarial waihanga e mahi ana hoki hei immunosuppressant. He putanga whakarerekē o te chloroquine, i hangaia kia ngawari ake ki tō tinana i te wā e whakarato tonu ana i te rongoā whai hua mō ētahi āhuatanga.

E mahi ana te rongoā mā te raru i te kōrero i waenga i ētahi pūtau i tō pūnaha ārai mate. Whakaarohia me te whakaiti i te rōrahi i runga i te urupare ārai mate kaha rawa e pā ana ki te mumura me te mamae i ngā āhuatanga pēnei i te rūmātiki me te lupus.

E whakaaro ana ngā tākuta ko te hydroxychloroquine he rongoā antirheumatic e whakarerekē ana i te mate, arā, DMARD mō te poto. Ko te tikanga ehara i te mea e rongoā ana i ngā tohu anake engari ka taea te whakaiti i te haere whakamua o ngā mate autoimmune i te roanga o te wā.

He aha te Hydroxychloroquine e whakamahia ana mō?

E rongoā ana te Hydroxychloroquine i ngā āhuatanga matua e toru: te ārai me te rongoā i te malaria, te rūmātiki, me te systemic lupus erythematosus. Ka tohua e tō tākuta i runga i tō āhuatanga motuhake me te hītori hauora.

Mō te malaria, ka ārai tēnei rongoā i te mate i te wā e haere ana koe ki ngā wāhi e kitea ana te malaria, me te rongoā i ngā mate kaha. E mahi ana mā te raru i te kaha o te pirinoa malaria ki te ora i roto i ō pūtau toto whero.

I roto i te mate rūmātiki, ka āwhina te hydroxychloroquine ki te whakaiti i te mamae o ngā hononga, te pōhū, me te mārō o te ata. He maha ngā tāngata e kite ana i te pai haere o ā rātou tohumate i roto i ngā marama maha o te rongoā, ā, ka āwhina pea ki te ārai i te kino haere o ngā hononga.

Mō ngā tūroro lupus, ka āwhina tēnei rongoā ki te whakahaere i ngā pūhihi kiri, te mamae o ngā hononga, me te ngenge. He tino whai hua ki te ārai i ngā mura o te lupus, ā, ka whakaiti pea i te hiahia mō ngā rongoā kaha ake pērā i te steroids.

I ētahi wā ka tohutohu ngā tākuta i te hydroxychloroquine mō ētahi atu āhuatanga autoimmune pērā i te mate o Sjögren, ētahi āhuatanga kiri rānei. Ko ēnei e kiia ana he whakamahinga "kore-tapanga", ko te tikanga kāore i whakaaetia te rongoā mō ēnei āhuatanga engari kua whakaatu i ngā painga i roto i ngā rangahau rongoā.

Me pēhea te mahi a te Hydroxychloroquine?

E kiia ana ko te hydroxychloroquine he rongoā kaha-waenga e mahi ana i te wā. Kāore i rite ki ngā rongoā mamae e mahi ana i roto i ngā hāora, ka hanga tēnei rongoā i roto i tō pūnaha, ā, ka roa pea te wiki, te marama rānei kia kitea ai ōna pānga katoa.

Ka mahi te rongoā mā te uru ki ētahi pūtau i roto i tō pūnaha ārai mate me te huri i te āhua o tā rātou mahi. Ka whakaiti i te hanga o ngā matū mumura e pā ana ki te mamae, te pōhū, me te kino o te kiko i roto i ngā mate autoimmune.

Mō te malaria, ka raru te hydroxychloroquine i te kaha o te pirinoa ki te keri i te hemoglobin i roto i ō pūtau toto whero. Ko te tikanga tēnei ka whakamate i te pirinoa me te ārai i te whakanui me te pā i te mate.

He pānga ngawari hoki te rongoā ki te tairongo o tō kiri ki te rā, ā, ka āwhina pea ki te whakaiti i ētahi momo pūhihi kiri. Koinei te take i tohutohutia ai mō ngā āhuatanga kiri e pā ana ki te lupus, ētahi atu mate autoimmune rānei.

Me pēhea taku tango i te Hydroxychloroquine?

Tangohia te hydroxychloroquine kia rite ki te tohutohu a tō tākuta, te tikanga kotahi, e rua rānei i te rā me te kai, te miraka rānei. Ko te tango me te kai ka āwhina ki te whakaiti i te pōpō o te puku, koinei tētahi o ngā pānga taha tino noa.

Horomia ngā papa katoa me te karaihe wai ki tonu. Kaua e kuru, e ngaungau, e whati rānei ngā papa, nā te mea ka pā tēnei ki te āhua o te rongoā e ngongohia ana, ā, ka piki ake pea ngā pānga taha.

Mēnā kei te tango koe mō te ārai malaria, tīmata te rongoā kotahi ki te rua wiki i mua i te haerenga ki tētahi wāhi e pā ana ki te malaria. Haere tonu te tango i ia wiki i a koe e noho ana i reira, ā, mō ngā wiki e whā i muri i tō hokinga ki te kāinga.

Mō te rūmātiki rumatoid, te lupus rānei, ka tango pea koe i ia rā. He mea whai hua te tango i te wā kotahi i ia rā kia mau tonu ngā taumata i roto i tō pūnaha, ā, kia mōhio koe ki ō horopeta.

Kaua e tango i te hydroxychloroquine me ngā antacids kei roto te konumohe, te konupora, te konupūmā rānei, nā te mea ka raru ēnei i te ngongotanga. Mēnā e hiahia ana koe ki te antacid, tangohia kia whā haora i mua, i muri rānei i tō horopeta hydroxychloroquine.

Kia Pēhea te Roa e Tango Ana ahau i te Hydroxychloroquine?

Ko te roa o te maimoatanga e whakawhirinaki ana ki tō āhua me te pai o tō urupare ki te rongoā. Mō te ārai malaria, ka tango koe mō te roa o tō haerenga me ngā wiki e whā i muri i te hokinga ki te kāinga.

Mō te rūmātiki rumatoid me te lupus, he maimoatanga wā-roa te hydroxychloroquine. He maha ngā tāngata e tango ana mō ngā tau hei āwhina i te whakahaere i ō rātou tohumate me te ārai i te pūmautanga o te mate.

Ka aroturukihia e tō tākuta tō urupare ki te rongoā, ā, ka whakatika pea i tō mahere maimoatanga i te wā. Ka kite ētahi tāngata i te whakapai ake i roto i ngā wiki e rua, i ētahi atu rānei ka hiahiatia kia toru ki te ono marama kia pā te painga katoa.

Kaua rawa e mutu te tango i te hydroxychloroquine ohorere me te kore e kōrero tuatahi ki tō tākuta. Mō ngā āhua ārai-a-tinana, ko te whakamutu ohorere ka arahi ki te pūmautanga o ngā tohumate ka kino ake pea i mua i tō tīmatanga i te maimoatanga.

Ka whakarite tō tākuta i ngā arotake auau hei aroturuki i tō ahunga whakamua me te mātakitaki mō ngā pānga taha. He mea nui ēnei haerenga mō te whakarite kia haumaru tonu te rongoā me te whai hua mō koe.

He aha ngā pānga taha o te Hydroxychloroquine?

He pai te whakawhitiwhiti a te nuinga o te tāngata ki te hydroxychloroquine, engari pērā i ngā rongoā katoa, ka pānga taha pea. Ko te rongo pai he mea kāore i te nuinga ngā pānga taha nui, ina koa ka whakamahia te rongoā i runga i te tika, me te aroturukihia i ngā wā katoa.

Me tīmata tātou ki ngā pānga taha tino noa ka pā ki a koe, he mea ngawari noa iho, ā, he maha ngā wā ka pai ake i te wā e whakatika ana tō tinana ki te rongoā.

Ngā pānga taha noa ko:

• Te pōrearea o te puku, te whakapairuaki, te mamae puku ngawari rānei
• Te korere, te tūtae wewete rānei
• Te ānini
• Te whanoke, te māmā rānei te mahunga
• Te pānga kiri, te mānukanuka rānei
• Te ngaro o te hiahia

He maha ngā wā ka iti ake ēnei tohumate i roto i ngā wiki torutoru i te wā e waia ana tō tinana ki te rongoā. Mā te tango hydroxychloroquine me te kai ka āwhina i te whakaiti i ngā pānga taha e pā ana ki te puku.

Ināianei, me kōrero tātou mō ētahi pānga taha kāore i te noa engari he nui ake te kino e hiahia ana kia aro mai te tākuta. Ahakoa ka puta ēnei i roto i te ōrau iti o te tāngata, he mea nui kia mōhio ki a rātou.

Ngā pānga taha kāore i te noa engari he nui te kino ko:

• Ngā huringa o te tirohanga, tae atu ki te tirohanga kāore i te mārama, te uaua rānei ki te kite
• Ngā raruraru whakarongo, te tangi rānei i ngā taringa
• Te ngoikore o te uaua, ngā raruraru rānei o te ruruku
• Ngā huringa o te ngākau, tae atu ki te pōuri, te āwangawanga rānei
• Te pānga kikokiko kāore i te noa, te toto rānei
• Ngā pānga kiri nui

Me whai whakaaro nui ki ngā raruraru tirohanga nā te mea ka tū tonu pea ki te kore e kitea wawe. Ka tūtohu tō tākuta i ngā whakamātautau kanohi i ngā wā katoa hei aroturuki i ngā huringa retinal, ka puta pea i te wā e whakamahia ana mō te wā roa.

He ētahi anō pānga taha onge engari he nui te kino e hiahia ana kia aro mai te tākuta i te wā tonu. Kāore ēnei i te noa, engari mā te mōhio ki a rātou ka āwhina i a koe ki te rapu āwhina i te wā e hiahiatia ana.

Ngā pānga taha onge engari he nui te kino ko:

• Ngā raruraru nui o te manawa
• Ngā tauhohenga mate pāwera nui me te uaua ki te manawa
• Ngā pākia, ngā kōpiko rānei
• Te kino nui o ngā uaua (rhabdomyolysis)
• Ngā mate toto e pā ana ki ngā pūtau toto mā, ki ngā pūtau rānei
• Ngā raruraru nui o te ate

Mēnā ka pā ki a koe ētahi o ēnei pānga kino nui, whakapā atu ki tō tākuta tonu, rapu rānei i te manaakitanga hauora ohorere. Kia mahara, he onge ēnei raruraru, engari he mea nui te mōhio wawe me te rongoā mō tō haumaru.

Ko wai kāore e tika kia tango Hydroxychloroquine?

Me karo e ētahi tāngata te hydroxychloroquine, me whakamahi rānei i raro i te tirotiro hauora tino tupato. Ka arotake tō tākuta i tō hītori hauora i mua i te whakarite i tēnei rongoā.

Kāore koe e tika kia tango hydroxychloroquine mēnā he pāwera koe ki a ia, ki te chloroquine, ki ētahi rānei o ōna whakauru. Ko ngā tauhohenga pāwera o mua ki ngā rongoā anti-malaria he take mārama ki te karo i tēnei rongoā.

Ko ngā tāngata e pā ana ki ētahi āhuatanga o te kanohi, ina koa ko ngā huringa o te retina, o te āpure rānei, me karo i te hydroxychloroquine. Ka taea e te rongoā te whakapōrearea i ngā raruraru o te kanohi, me te whakatū huringa kitea tonu.

Mēnā he raruraru nui tō manawa, ina koa ko te āhuatanga e kīia nei ko te QT prolongation, kāore pea te hydroxychloroquine i te haumaru mōu. Ka taea e te rongoā te pā ki te pūnaha hiko o tō manawa, me te whakapōrearea i ngā raruraru o te manawa.

Me tūpato anō mō ētahi atu āhuatanga. Ka whakatau tō tākuta i ngā painga ki ngā tūponotanga mēnā he āhuatanga ōna.

Ngā āhuatanga e hiahia ana kia tūpato:

• Te mate tākihi, te iti rānei o te mahi tākihi
• Te mate ate, ngā raruraru rānei o te mahi ate
• Ngā mate toto pēnei i te anemia, te iti rānei o te pūtau toto mā
• Te ngoikoretanga o te Glucose-6-phosphate dehydrogenase (G6PD)
• Psoriasis, porphyria rānei
• Ngā raruraru rongo, ngā mate taringa rānei

Me te hapū me te whāngai ū, me whai whakaaro motuhake. Ahakoa te nuinga e whakaaro ana he haumaru ake te hydroxychloroquine i ētahi atu rongoā mō ngā mate ā-ārai i te wā e hapū ana, ka āta aromatawai tō tākuta mēnā ka nui ake ngā painga i ngā tūponotanga.

Ngā Ingoa Waitohu o Hydroxychloroquine

Ko Plaquenil te ingoa waitohu rongonui mō te hydroxychloroquine i te United States. Kua wātea tēnei waitohu mō ngā tau tekau, ā, koinei te momo e mōhio ana te nuinga o ngā tākuta me ngā tūroro.

He wātea whānui hoki ngā momo generic o te hydroxychloroquine, ā, kei roto anō te whakauru kaha kotahi i te Plaquenil. Ko ēnei momo generic te nuinga he iti ake te utu, ā, he rite tonu te whai hua ki te rongoā waitohu.

Ka taea e tō whare rongoā te whakakapi i tētahi momo generic mēnā kāore tō tākuta i tuhi motuhake i te "ingoa waitohu anake" i runga i tō rongoā. Me tutuki ngā momo generic me ngā momo waitohu i ngā paerewa haumaru me te whai hua kotahi i whakatakotohia e te FDA.

Mēnā kei te huri koe i waenga i ngā kaihanga rerekē o te hydroxychloroquine, whakamōhio atu ki tō tākuta. Ahakoa me mahi rite tonu ngā rongoā, he tāngata tōtika ki ngā rerekētanga o ngā whakauru kore-kaha, o ngā tukanga whakangao rānei.

Ngā Kōwhiringa kē mō Hydroxychloroquine

He maha ngā rongoā kē ka taea te rongoā i ngā āhuatanga kotahi i te hydroxychloroquine, ahakoa ko te kōwhiringa pai rawa atu ka whakawhirinaki ki tō āhuatanga motuhake me te hītori hauora. Ka āwhina tō tākuta i a koe ki te kimi i te kōwhiringa tino tika mēnā kāore te hydroxychloroquine i te tika mōu.

Mō te rūmātiki, ko ētahi atu DMARD pēnei i te methotrexate, sulfasalazine, leflunomide rānei, he kōwhiringa kē pea. Ko ngā rongoā koiora pēnei i te adalimumab, etanercept rānei, he kōwhiringa anō mō ngā tāngata e kaha ake ana te mate.

Ka whai hua pea ngā tūroro Lupus mai i ētahi atu rongoā antimalarial pērā i te chloroquine, ahakoa he nui ake ngā pānga taha o tēnei rongoā i te hydroxychloroquine. Ka whakamahia hoki ngā rongoā immunosuppressive pērā i te methotrexate, mycophenolate mofetil rānei mō te rongoā lupus.

Mō te ārai malaria, ko ngā kōwhiringa kē atu ko te doxycycline, mefloquine, atovaquone-proguanil rānei. Ko te kōwhiringa pai rawa atu ka whakawhirinaki ki te wāhi e haere ana koe me ō āhuatanga tūpono takitahi.

Ka whakaarohia e tō tākuta ngā āhuatanga pērā i ō ētahi atu āhuatanga hauora, ngā rongoā e tango ana koe, me te pai o tō urupare ki ngā rongoā o mua i te wā e tūtohu ana i ngā kōwhiringa kē atu.

He Pai Ake Anei te Hydroxychloroquine i te Methotrexate?

Kāore te hydroxychloroquine me te methotrexate i te "pai ake" i te katoa – he rongoā rerekē ēnei me ō rātou painga me ō rātou ngoikoretanga. Ko te kōwhiringa pai rawa atu mōu ka whakawhirinaki ki tō āhuatanga motuhake, te kaha o ngā tohumate, me te urupare takitahi ki te rongoā.

Ko te tikanga, he ngawari ake te hydroxychloroquine me te iti ake o ngā pānga taha nui, he pai ai hei rongoā tuatahi mō te rheumatoid arthritis ngawari ki te āhua. He tino ātaahua tēnei rongoā nā te mea kāore e pēhi i tō pūnaha ārai mate i te nui o te methotrexate.

Ko te tikanga, he whai hua ake te methotrexate mō te rheumatoid arthritis nui, ā, he maha ngā wā ka whakaarohia ko te paerewa koura DMARD. Heoi, e hiahia ana kia nui ake te aroturuki me te nui ake o ngā pānga taha, tae atu ki ngā raruraru ate me te piki ake o te tūponotanga o te mate.

He maha ngā tākuta ka tīmata ki te hydroxychloroquine mō ngā tūroro kua kitea i te wā tata nei, ina koa ko te hunga he ngawari ngā tohumate. Ki te kore te hydroxychloroquine e whai hua i muri i ētahi marama, ka huri rātou ki te tāpiri rānei i te methotrexate.

Ka tango tahi ētahi tāngata i ngā rongoā e rua, nā te mea ka mahi tahi rātou ki te whakarato i te pai ake o te whakahaere i ngā tohumate i te rongoā kotahi. Mā tō tākuta e āwhina ki te whakatau i te huarahi pai rawa atu i runga i tō āhuatanga takitahi.

Ngā Pātai Auau mō Hydroxychloroquine

He Haumaru te Hydroxychloroquine mō te Mate Ngākau?

Me āta arotake te Hydroxychloroquine mō ngā tāngata e mate ana i te ngākau, otirā mō te hunga e raru ana i te manawataki. Ka pā te rongoā nei ki te pūnaha hiko o tō ngākau, ā, ka kino ake pea ētahi momo mate ngākau.

Mēnā he mate ngākau tōu, tērā pea ka tono tō tākuta i tētahi electrocardiogram (EKG) i mua i te tīmatanga o te hydroxychloroquine, ā, ka āta tirotiro pea i tō manawataki i ia wā i te wā e rongoā ana. Mā tēnei e āwhina kia mōhio ai he haumaru te rongoā nei mō tō mate ngākau motuhake.

Ko te hunga e raru ana i te QT prolongation, tētahi momo motuhake o te raruraru manawataki, me karo te hydroxychloroquine. Heoi anō, ko te hunga e mate ana i ētahi atu momo mate ngākau ka taea te tango i te rongoā nei me te āta tirotiro.

Me pēhea ahau ki te tango nui rawa i te Hydroxychloroquine?

Mēnā ka tango nui rawa koe i te hydroxychloroquine i te mea i whakaritea, whakapā atu ki tō tākuta, ki te pokapū whakahaere paitini rānei i te wā tonu. Ko te tango nui rawa ka pā mai ngā pānga taha kino, tae atu ki ngā raruraru manawataki, ngā pākia, me te heke nui o te pēhanga toto.

Kaua e tatari kia kite mena ka puta mai ngā tohumate – he mōrearea te nui rawa o te hydroxychloroquine, ā, tērā pea ka hiahiatia te rongoā hauora tonu. Mēnā kei te pā mai ngā tohumate pēnei i te whanoke, te uaua ki te hā, te huringa rānei o te manawataki, rapua te manaakitanga hauora ohorere i te wā tonu.

Puritia te pounamu rongoā ki a koe i te wā e rapu ana i te āwhina hauora, nā te mea ka āwhina tēnei mōhiohio i ngā kaiwhakarato hauora ki te rongoā tika i a koe. Kaua rawa e ngana ki te whakapōkae ki te kore i tohutohutia e tētahi tohunga hauora.

Me pēhea ahau ki te ngaro i tētahi horopeta o Hydroxychloroquine?

Mēnā ka ngaro koe i tētahi horopeta o te hydroxychloroquine, tangohia i te wā tonu ka mahara koe, ki te kore e tata ana te wā mō tō horopeta e whai ake nei. I taua wā, waiho te horopeta i ngaro, ka haere tonu ki tō hōtaka horopeta auau.

Kaua rawa e rua ngā horopeta hei whakakapi i tētahi i ngaro, tērā pea ka piki ake tō tūponotanga ki ngā pānga taha. Mēnā kei te tango koe i te hydroxychloroquine mō te ārai malaria, ā, ka ngaro i a koe tētahi horopeta, whakapā atu ki tō tākuta mō te tohutohu me pēhea te haere tonu.

Mō ngā āhuatanga autoimmune, ko te ngaro i tētahi horopeta i ētahi wā, kāore pea e puta he raruraru tonu, engari ngana ki te pupuri i te horopeta rite tonu mō ngā hua pai rawa atu. Whakaarohia te whakatakoto i ngā whakamaharatanga waea, te whakamahi rānei i tētahi kaiwhakarite pire hei āwhina i a koe ki te mahara ki ō horopeta.

Āhea Ānei Ka Taea e Au te Kati te Tango Hydroxychloroquine?

Kaua rawa e kati te tango hydroxychloroquine me te kore e kōrero tuatahi ki tō tākuta. Mō ngā āhuatanga autoimmune pērā i te rheumatoid arthritis me te lupus, ko te whakamutu i te rongoā ka puta he pūhaehae o ngā tohumate, tērā pea ka kino ake i mua i te rongoā.

Mā tō tākuta koe e āwhina ki te whakatau i te wā e tika ana kia mutu, kia whakaiti rānei i tō horopeta i runga i ō tohumate, te mahi mate, me te hauora whānui. Ētahi tāngata pea me tango hydroxychloroquine mō ngā tau maha kia mau tonu te mana whakahaere tohumate pai.

Mēnā kei te pā tōna taha ki a koe, kōrero ki tō tākuta mō te whakatika i tō horopeta, te huri rānei ki tētahi rongoā rerekē, kaua ki te whakamutu ohorere. He maha ngā huarahi hei whakahaere i ngā pānga taha i te wā e haere tonu ana te rongoā.

Mō te ārai malaria, me haere tonu koe ki te tango i te rongoā mō te roanga katoa i whakaritea, tae atu ki ngā wiki e whā i muri i te wehenga atu i tētahi wāhi e pā ana ki te malaria. Ko te whakamutu wawe rawa ka waiho koe kia whakaraerae ki te mate.

Ka Taea e Au te Inu Waipiro i te Wā e Tango Ana i te Hydroxychloroquine?

Ko te inu waipiro i te āhua pai e whakaaetia ana i te wā e tango ana i te hydroxychloroquine, engari he mea pai ki te kōrero i tēnei ki tō tākuta. Ka pā tahi te waipiro me te hydroxychloroquine ki tō ate, nō reira ko te whakakotahi i a rāua ka piki ake te tūponotanga o ngā raruraru ate.

Ki te whai koe i te mate ate, kei te tango rongoā rānei e pā ana ki tō ate, tō tākuta pea e kī ana kia karo katoa i te waipiro. Ko ngā tāngata e whai ana i te rūmātiki, i te lūpus rānei, e tango ana hoki i te methotrexate me tino tūpato ki te inu waipiro.

Ka taea hoki e te waipiro te whakanui i ētahi pānga taha o te hydroxychloroquine, pērā i te whanoke, i te pōpōtanga puku rānei. Kia mōhio ki tō āhua i te wā e whakakotahi ana koe i te waipiro me tō rongoā, ā, whakatika kia rite.

Kia pono tonu ki tō tākuta mō tō inu waipiro kia taea e rātou te tohutohu pai mō tō āhuatanga motuhake. Mā tēnei mōhiohio e āwhina ana i a rātou ki te aroturuki i tō hauora me te whakatika i tō mahere rongoā ki te hiahiatia.