He aha te Istradefylline: Ngā Whakamahinga, Inenga, Ngā Pānga Taha me Ētahi Atu

He rongoā a Istradefylline e āwhina ana ki te whakahaere i ngā wā "whakaweto" i roto i te mate o Parkinson ina kore e pai te mahi o tō rongoā auau. Ki te mea kei a koe, kei tētahi rānei e manaaki ana koe te mate o Parkinson, tērā pea kua kite koe i ētahi wā ka ngaro te pānga o ngā rongoā matua i mua i te wā e tika ana te inenga e whai ake nei, ka waiho koe kia mārō, kia uaua rānei te neke mārire.

Ka mahi tēnei rongoā hei rongoā tāpiri ki tō rongoā o Parkinson o nāianei. I hangaia hei āwhina i te whakaiti i aua wā e hōhā ana ka hoki mai anō ō tohumate i waenga i ngā inenga, e whai wāhi ana koe ki te whakawātea i te rā katoa.

He aha te Istradefylline?

He momo rongoā a Istradefylline e kīia ana he kaiwhakatūtū i te kaiwhakawhiwhi adenosine A2A. I roto i ngā kupu māmā, ka mahi mā te aukati i ētahi tohu i roto i tō roro ka raru i te neke mārire me te ruruku.

Whakaarohia he rongoā āwhina e mahi tahi ana me tō rongoā matua o Parkinson. Ahakoa e whakarato ana tō rongoā tuatahi (te nuinga o te levodopa/carbidopa) i ngā painga matua, ka uru mai a istradefylline ki te āwhina i te pupuri i aua painga i te rā katoa.

Ka tae mai te rongoā i roto i te puka papa, ka tangohia mā te waha. Kua whakaaetia motuhake mō ngā pakeke e mate ana i te mate o Parkinson e pā ana ki ngā rereketanga o te motuka, arā, ko aua wā ka puta mai, ka ngaro ngā tohumate.

He aha te Istradefylline e whakamahia ana?

Ka whakamahia te Istradefylline ki te rongoā i ngā wā "whakaweto" i roto i ngā tāngata e mate ana i te mate o Parkinson. Ko ēnei wā whakaweto he wā ka mutu te mahi o tō rongoā Parkinson auau, ka hoki mai anō ō tohumate pēnei i te wiri, te mārō, me te neke pōturi.

He maha ngā tāngata e mate ana i te mate o Parkinson ka pā ki ēnei huringa i te wa e haere ana te mate. Ka kite pea koe e pai ana te rongoā mō ētahi haora i muri i te tango, engari ka tīmata koe ki te pūhaehae, ki te wiri rānei i mua i tō horopeta e whai ake nei.

E whakamahia ana tēnei rongoā me te levodopa/carbidopa, kaua rawa e whakamahia ana anake. I hangaia hei āwhina i te whakanui i ngā wā e pai ana koe, me te whakaiti i te wā e noho ana koe i roto i aua wā kore pai.

Me pēhea te mahi a Istradefylline?

Ka mahi a Istradefylline mā te aukati i ngā kaiwhiwhi adenosine A2A i tō roro. Ko ēnei kaiwhiwhi te tikanga ka whakaiti i te mahi o te dopamine, te matū roro e āwhina ana ki te whakahaere i te nekehanga, ā, kei te ngaro i te mate o Parkinson.

Mā te aukati i ēnei kaiwhiwhi, ka taea e istradefylline te mahi pai ake o te dopamine. Ko te tikanga tēnei ka taea e tō rongoā Parkinson te whakarato i ngā painga rite tonu puta noa i te rā, me te whakaiti i aua wā kore pai e whakararuraru ana.

E kiia ana he rongoā kaha-ā-waenganui e whakarato ana i te tautoko pūmau, kaua i ngā huringa nui. Ko te nuinga o ngā tāngata ka kite i ngā whakapainga haere i roto i te wā kore i roto i ngā wiki maha o te rongoā, kaua i ngā pānga nui tonu.

Me pēhea taku tango i te Istradefylline?

Tangohia te istradefylline kia rite ki te tohutohu a tō tākuta, te tikanga kotahi i te rā. Ka taea e koe te tango me te kore rānei he kai, ko tēhea te mea e pai ana ki a koe.

He pai ake te tango i tō horopeta i te wā kotahi i ia rā hei āwhina i te pupuri i ngā taumata pūmau i roto i tō pūnaha. He maha ngā tāngata e kite ana he āwhina ki te tango me ā rātou rongoā o te ata hei wāhanga o ā rātou mahi o ia rā.

Mēnā he raruraru tō horomia i ngā papa, ka taea e koe te kuru i ngā papa istradefylline me te whakaranu ki te aporo, ki te pūhi rānei. Heoi, kaua e ngaungau, e wawahi rānei i ngā papa ki te kore te tākuta e kī atu ki a koe he pai ki te mahi.

Me haere tonu ki te tango i ō rongoā Parkinson's katoa e rite ana ki te tohutohu. Ko te Istradefylline he mea hei mahi tahi me tō rongoā o nāianei, kaua hei whakakapi.

Kia Pēhea te Roa e Tango Ana ahau i te Istradefylline?

Ko te Istradefylline te tikanga he rongoā wā-roa e haere tonu ana koe ki te tango i te wā e āwhina ana ki te whakahaere i ō tohu Parkinson's. Ko te nuinga o te hunga e whai hua ana mai i tēnei rongoā me tango tonu kia mau tonu ai ngā whakapainga.

Ka tīmata pea koe ki te kite i ētahi painga i roto i ngā wiki tuatahi, engari ka roa pea te 12 wiki kia pōti ai i ngā pānga katoa. He mea noa tēnei whakapainga haere, ā, kāore i te kī ana kāore te rongoā e mahi ana.

Ka tirohia e tō tākuta i ngā wā katoa te pai o te mahi a te rongoā mōu, ā, ka whakatika pea i tō mahere rongoā i te roanga o te wā. Kaua rawa e mutu te tango i te istradefylline ohorere me te kore e kōrero tuatahi ki tō kaiwhakarato hauora, nā te mea ka hoki mai, ka kino rānei ō wā wahangu.

He Aha ngā Pānga Taha o te Istradefylline?

Pērā i ngā rongoā katoa, ka taea e te istradefylline te pānga taha, ahakoa kāore katoa te tangata e pōti ana. Mā te māramatanga ki ngā mea e tūmanakohia ana ka āwhina koe ki te pōti i te pai ake, ā, ki te mōhio ki te wā hei whakapā atu ki tō tākuta.

Ko ngā pānga taha tino noa he ngawari tonu, ā, he maha ngā wā ka pai ake i te wā e whakatika ana tō tinana ki te rongoā:

• Te whakapairuaki, te puku rānei
• Te whanoke, te māmā rānei
• Te uaua ki te moe, te huringa rānei i ngā tauira moe
• Te pāhohe
• Ngā tūponotanga (te kite, te rongo rānei i ngā mea kāore i reira)

Ko ēnei pānga taha te tikanga ka iti ake te kitea i muri i ētahi wiki o te rongoā. Mā te tango i te rongoā me te kai ka āwhina ki te whakaiti i te whakapairuaki, ā, mā te noho wai ka āwhina pea ki te pāhohe.

Ka pōti pea ētahi tāngata i ngā pānga taha nui ake e hiahia ana ki te āwhina hauora. Ahakoa he iti noa iho ēnei, he mea nui kia mōhio ki ngā mea hei matakitaki:

• Ngā hiahia rerekē, ngā whanonga rānei (pēnei i te petipeti nui, te hoko, te kai rānei)
• Ngā huringa nui o te ngākau, te pōuri rānei
• Te piki nui o ngā nekehanga kore e hiahiatia
• Te mamae o te uma, te ngākau rerekē rānei
• Te whanoke nui, te ngaro rānei

Mēnā ka pā ki a koe ētahi o ēnei pānga nui ake, whakapā atu ki tō tākuta i te wā tonu. Ka taea e rātou te āwhina ki te whakatau mēnā me whakatika te rongoā, mēnā rānei e hiahia ana koe ki te tautoko atu.

Ko wai kāore e tika kia tango Istradefylline?

Kāore a Istradefylline e tika ana mō te katoa, ā, ko ētahi āhuatanga hauora, rongoā rānei ka kore e haumaru. Ka āta arotake tō tākuta i tō hītori hauora i mua i te whakahau i tēnei rongoā.

Kāore koe e tika kia tango i te istradefylline mēnā he pānga pānga koe ki a ia, ki ōna kai rānei. Kōrero atu ki tō tākuta mō ngā pānga pānga i mua ki ngā rongoā, ahakoa kāore e pēnei ana te ahua.

Ko ngā tāngata e whai ana i ētahi āhuatanga hauora ka hiahia ki te aroturuki motuhake, kāore rānei e taea te tango i tēnei rongoā i runga i te haumaru:

• Te mate tākihi nui
• Te mate ate nui
• Te hītori o ngā raruraru o te manawa
• Te psychosis kaha, ngā āhuatanga hauora hinengaro nui rānei
• Te hapū, te whāngai ū rānei

Ka taea e ētahi rongoā te pā tahi ki te istradefylline, ka kore pea e whai hua, ka piki ake rānei ngā pānga taha. Me mōhio ki te kōrero atu ki tō tākuta mō ngā rongoā katoa e tango ana koe, tae atu ki ngā rongoā kaore e hiahiatia he whakahaunga, me ngā tāpiringa.

Ingoa Waitohu Istradefylline

Ka hokona te Istradefylline i raro i te ingoa waitohu Nourianz i te United States. Koinei te huarahi tino noa ka kite koe i te whakahau me te tohatoha i ngā whare rongoā.

I te kōrero ki tō tākuta, ki te kaimātai rongoā rānei, ka taea e koe te whakamahi i te ingoa whānui (istradefylline) te ingoa waitohu rānei (Nourianz). Ka mārama rātou ki te rongoā e kōrero ana koe.

I tēnei wā, ko Nourianz anake te momo waitohu e wātea ana i te US, ahakoa ka wātea pea ngā momo rongoā whānui ā muri ake nei i te pau o ngā pātēneti.

Ngā Kōwhiringa kē mō Istradefylline

Mēnā kāore a istradefylline i te tika mōu, he rongoā anō hei āwhina i te whakahaere i ngā wā 'whakaweto' i te mate o Parkinson. Ka taea e tō tākuta te kōrero mō ēnei kōwhiringa i runga i tō āhuatanga motuhake.

Ētahi atu rongoā e mahi ana i te ara rite ki te whakaiti i te wā 'whakaweto' ko:

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• Safinamide (Xadago) - tētahi atu rongoā tāpiri
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• Rasagiline (Azilect) - he aukati MAO-B
\n
• Selegiline (Eldepryl) - tētahi atu aukati MAO-B
\n
• Entacapone (Comtan) - he aukati COMT
\n

Ka whakaaro pea tō tākuta ki te whakatika i tō hōtaka inenga levodopa/carbidopa o nāianei, ki te huri rānei ki tētahi momo rerekē i mua i te tāpiri i tētahi rongoā hou. Ko te kōwhiringa pai rawa atu ka whakawhirinaki ki ō tohu motuhake, ētahi atu āhuatanga hauora, me te pēhea i urupare ai koe ki ngā rongoā o mua.

He Pai Ake Anei A Istradefylline I A Rasagiline?

Ka taea e te istradefylline me te rasagiline te āwhina i te whakaiti i ngā wā 'whakaweto' i te mate o Parkinson, engari e mahi ana rāua mā ngā tikanga rerekē i tō roro. Kāore he whakautu māmā mō tēhea te mea

He maha ngā tāngata e pā ana ki te mate ngākau ka taea te tango i te istradefylline me te haumaru, engari me mātakitaki tata atu pea rātou. Ka pā te rongoā ki te manawa i ētahi wā, nō reira me arotake tō tākuta i tō hauora ngākau i mua i te tīmatanga o te rongoā.

Mēnā he hītori tō rātou mō ngā raruraru ngākau, ka tono pea tō tākuta i tētahi EKG (te whakamātautau manawa) i mua i te tīmatanga o te tango i te istradefylline, ā, pea i te wā o te rongoā. Mā tēnei e āwhina ai kia mōhio kei te pā te rongoā ki tō manawa.

Kaua e waiho ngā āwangawanga ngākau hei aukati i a koe ki te kōrero i tēnei kōwhiringa rongoā ki tō tākuta. He maha ngā tāngata e pā ana ki ngā āhuatanga ngākau e tango ana i te istradefylline me te angitu me te mātakitaki tika.

Q2. Me Pēhea Taku Mahi Mēnā Ka Tango Au i te Nui Rawa o te Istradefylline?

Mēnā ka tango koe i te nui rawa o te istradefylline i te mea i whakaritea, whakapā atu ki tō tākuta, ki te pokapū whakahaere paitini rānei i te wā tonu. Mā te tango i te nui rawa e whakanui ai i tō tūponotanga ki ngā pānga taha pēnei i te whakapairuaki, te whanoke, te huringa rānei o te manawa.

Kaua e ngana ki te

Me mutu anake te tango i te istradefylline i raro i te tohutohu a tō tākuta. I te mea i hangaia hei āwhina i te whakahaere i ngā tohumate o Parkinson e haere tonu ana, ka hoki mai pea ō wāhanga okioki ki te mutu te tango.

Ka tūtohu pea tō tākuta kia mutu te rongoā mena kei te pā koe i ngā pānga taha nui atu i ngā painga, mena kua piki ake tō mate Parkinson ki te wāhi e tika ana ētahi atu rongoā.

Mēnā ka whakatau koe me tō tākuta ki te mutu te istradefylline, ka heke haere koe i te rongoā, kaua e mutu ohorere. Mā tēnei e ārai te pikinga o ngā tohumate.

Q5. Ka taea e au te inu waipiro i te wā e tango ana i te Istradefylline?

He pai ake te whakaiti i te waipiro i te wā e tango ana i te istradefylline. Ka taea e te waipiro te whakanui i te tūponotanga o te whanoke, ā, ka raru pea i te pai o te mahi o te rongoā.

Mēnā ka whiriwhiri koe ki te inu i ētahi wā, inu i te āhua tika, ā, kia aro ki te āhua o tō tinana. E kite ana ētahi tāngata ahakoa te iti o te waipiro ka nui ake te kore tū me te whanoke i te wā e honoa ana ki tēnei rongoā.

Kōrero ki tō tākuta mō ō tikanga inu waipiro kia taea e rātou te whakarato i ngā tohutohu whaiaro i runga i tō hauora whānui me ētahi atu rongoā e tango ana koe.