He aha te Ivabradine: Ngā Whakamahinga, te Inenga, ngā Pānga taha, me ētahi atu mea

Ko te Ivabradine he rongoā ngākau e āwhina ana ki te whakaiti i te tere o tō ngākau ina tere rawa te patupatu. He rerekē tana mahi i ētahi atu rongoā ngākau mā te aro ki tētahi wāhi motuhake o te pūnaha hiko o tō ngākau e kīia ana ko te "auau katakata", te auau If rānei. Mā tēnei ka whai hua ai mō te hunga e tere ana ō rātou ngākau ahakoa kei te okioki, e āwhina ana i a rātou kia pai ake te tū, me te whakaiti i te pēhanga ki runga i ō rātou uaua ngākau.

He aha te Ivabradine?

Ko te Ivabradine he rongoā rāhui e noho ana ki tētahi rōpū rongoā e kīia ana ko te hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. I te mea he māmā, he kaiwhakahaere i te tere o te ngākau e mahi ana mā te aukati i ētahi tohu hiko i tō ngākau. Kāore i rite ki ngā beta-blockers, ki ngā calcium channel blockers rānei, ka aro te ivabradine ki te kaiwhakatere tūturu o te ngākau me te kore e pā ki tō toto toto, ki te kaha rānei o ngā kōpā o tō ngākau.

I whakawhanakehia te rongoā hei whakatika i tētahi hiahia motuhake mō te hunga e tere rawa ana te patupatu o ō rātou ngākau, ina koa ko te hunga e mate ngākau ana, e angina pumau ana rānei. E tuku ana i tētahi huarahi ahurei ki te whakahaere i te tere o te ngākau e whai hua ana ina kāore ētahi atu rongoā e tika ana, e whai hua ana rānei i a rātou anō.

He aha te Ivabradine e whakamahia ana?

Ko te Ivabradine te mea nui e rāhui ana mō ngā āhuatanga ngākau e rua e whai pānga nui ana te whakahaere i te tere o te ngākau ki tō oranga. Ka tohutohu pea tō tākuta i tēnei rongoā ina tere tonu tō ngākau, e pēhi ana i tō pūnaha cardiovascular.

Ko te whakamahinga tuatahi ko te korenga ngakau mau tonu i roto i nga pakeke he manawataki ngakau noa engari ko te tere o te ngakau kei runga ake i te 70 pao ia meneti ahakoa te tango i te horopeta teitei rawa atu o nga beta-blockers. I roto i tenei ahuatanga, ka awhina te ivabradine ki te whakaiti i te kawenga mahi ki runga i to ngakau, ka taea e ia te papu i te pai ake, me te whakapai ake i o tohu penei i te poto o te manawa me te ngenge.

Ko te whakamahinga tuarua ko te angina pumau mau tonu, he mamae o te uma ka puta i te wa kaore to ngakau e whiwhi toto whai-hauora. Ki te kore e pai nga beta-blockers mo koe, kare ranei e pai te whakahaere, ka taea e te ivabradine te awhina ki te whakaiti i to tere o te ngakau me te whakaiti i te auau o nga wahanga angina.

Me pehea te mahi a Ivabradine?

Ka mahi a Ivabradine ma te aro ki te kaiwhakahaere tere o to ngakau, me te aukati i te

Me tango tika a Ivabradine i runga i nga tohutohu a tō tākuta, te tikanga e rua nga wa ia rā me ngā kai. Mā te tango me te kai ka āwhina tō tinana ki te ngongo tika i te rongoā, ā, ka whakaiti i te tūponotanga o te pōpō i te puku. Ko te wā o āu horopeta kia rite tonu te āhua, tata ki te 12 hāora te wā i waenga i ngā horopeta.

Ka taea e koe te tango ivabradine me te miraka, te wai, me ētahi inu kore-waipiro i te wā o tō kai. Ko te mea nui kia whai kai i tō puku i te wā e tango ana koe i ia horopeta. Kāore he mea nui kia nui te kai - ahakoa he paramanawa māmā, he parakuihi iti, he tina rānei ka pai.

Ka tīmata pea tō tākuta i a koe ki te horopeta iti, ā, ka piki haere i runga i te āhua o te urupare o tō ngākau me te pai o tō whakamanawanui i te rongoā. Kaua rawa e whakatika i tō horopeta i runga i tō ake, me mātakitaki tō reiti ngākau kia mōhio ai kei te mahi haumaru me te whai hua te rongoā.

Mēnā me whakamutu te tango ivabradine, ka ārahi tō tākuta i a koe mā te whakaiti haere, kaua e mutu ohorere. Mā tēnei e āwhina ki te ārai i ngā pānga ohorere ki tō reiti ngākau.

Kia Pēhea te Roa e Tango Ai au i te Ivabradine?

Ko te tikanga ka tohua te ivabradine hei rongoā wā-roa, te tikanga ka tango pea koe i te rongoā mō ngā marama, ngā tau rānei, kaua i ngā wiki noa. Kei runga i tō āhua ngākau me te pai o tō urupare ki te rongoā te roa tika.

Mō te hunga e mate ana i te ngoikore o te ngākau, ka noho te ivabradine hei wāhanga o te mahere rongoā wā-roa me ētahi atu rongoā ngākau. Ka mātakitaki tō tākuta i tō reiti ngākau me te mahi ngākau whānui kia whakatau mēnā kei te whai hua tonu te rongoā mō koe.

Mēnā kei te tango koe i te ivabradine mō te angina pumau, ka whakawhirinaki te roa o te rongoā ki ō tohumate me te pai o te mahi o ētahi atu rongoā. Ka hiahia pea ētahi tangata ki te tango tonu, engari ka taea e ētahi te whakaiti, te whakamutu rānei i te rongoā mēnā ka pai ake tō rātou āhua i ngā huringa o te oranga, ētahi atu rongoā rānei.

Ka whakarite tō tākuta i ngā arotake i ngā wā katoa hei aromatawai mēnā me haere tonu koe ki te tango i te ivabradine. Ka whakaarohia e rātou ngā āhuatanga pēnei i te urupare o tō ngākau, ngā pānga taha e pā ana ki a koe, me ngā huringa i roto i te hauora o tō ngākau.

He aha ngā Pānga Taha o te Ivabradine?

Pērā i ngā rongoā katoa, ka taea e te ivabradine te pānga taha, ahakoa he maha ngā tāngata e pai ana ki te tango. Mā te māramatanga ki ngā mea e tūmanakohia ana ka āwhina koe ki te whai māia ki tō rongoā, me te mōhio ki te wā ki te whakapā atu ki tō kaiwhakarato hauora.

Ko ngā pānga taha e tino kitea ana ka pā ki a koe ko ngā raruraru tirohanga, inā koa te kite i ngā mārama kanapa, i ngā hāro rānei huri noa i ngā mārama. Ka pā tēnei nā te mea ka pā te ivabradine ki te mahi hiko i roto i te retina o ō kanohi. Ko ēnei huringa tirohanga he wā poto noa iho, ā, he maha ngā wā ka pai ake i te wā e urutau ana tō tinana ki te rongoā.

Anei ngā pānga taha e tino kitea ana e te iwi:

• Ngā āhuatanga mārama, phosphenes rānei (te kite i ngā wāhi kanapa, i ngā uira rānei o te mārama)
• Te tirohanga pōkaikaha, inā koa i te mārama kanapa
• Te tere o te ngākau (bradycardia)
• Te ānini
• Te whāwhā, te māmā rānei
• Te ngenge, te ngenge rānei

Ko ēnei pānga taha he ngawari noa iho, ā, ka pai ake i te wā e urutau ana tō tinana ki te rongoā. He maha ngā tāngata e kite ana ka taea e rātou te haere tonu i ā rātou mahi o ia rā, kāore he raruraru nui.

Ko ētahi pānga taha kāore i te kitea, engari he nui ake te kino, me whai wāhi tonu te rongoā. Ahakoa he onge, me mōhio koe ki ēnei mea ka taea kia rapua he āwhina mēnā e tika ana.

• Ngā manawataki ngākau kōaro (atrial fibrillation)
• Te tere o te ngākau tino puhoi (kei raro iho i te 50 ngā patu i ia meneti)
• Te mamae o te uma, te kino rānei o te angina
• Te whāwhā nui, te ngaro rānei
• Te poto o te manawa, te uaua rānei ki te manawa

Mēnā ka pā mai ētahi o ēnei pānga kino, whakapā atu ki tō tākuta tonu, rapu rānei i te manaakitanga hauora ohorere. Ko tō haumaru te mea matua, ā, me arotake wawe ēnei tohumate.

Ko wai kāore e tika kia tango Ivabradine?

Kāore a Ivabradine e tika ana mō te katoa, ā, he wāhi tērā e kore ai tō tākuta e whakahau i tēnei rongoā. Mā te māramatanga ki ēnei aukatinga e āwhina i tō haumaru me te whai hua o tō mahere rongoā.

Kāore koe e tika kia tango ivabradine mēnā he raruraru o te manawa, ina koa mēnā kāore ō manawa i te tikanga. I hangaia te rongoā nei kia mahi tahi me te kaiwhakatere tūturu o tō manawa, nō reira kāore e whai hua, e haumaru rānei mō te hunga he manawa rerekē pēnei i te atrial fibrillation.

Ko ēnei ngā āhuatanga matua e ārai ana i a koe ki te tango ivabradine:

• Te tere o te manawa i raro iho i te 70 ngā patupatu i te meneti i mua i te rongoā
• Te ngoikore o te manawa, te pōro rānei o ngā tohumate o te ngoikore o te manawa
• Te toto iti (hypotension)
• Ngā raruraru ate nui
• Te hapū, te whāngai u rānei
• Te pakeke i raro i te 18 tau

Ka tūpato anō tō tākuta ki te whakahau ivabradine mēnā he āhuatanga ōna e pā ana ki te rongoā, e whakanui rānei i tō tūponotanga ki ngā pānga kino.

I tua atu, he maha ngā rongoā ka pā tahi ki a ivabradine, ina koa ērā e pā ana ki ngā enzyme kotahi i tō ate e tukatuka ana i te rongoā. Ka arotake tō tākuta i ō rongoā katoa i tēnei wā kia mōhio kāore he pānga kino i mua i te tīmatanga o te tango ivabradine.

Ngā Ingoa Waitohu o Ivabradine

E wātea ana a Ivabradine i raro i ētahi ingoa waitohu, ko Corlanor te ingoa waitohu tino nui i te United States. I ētahi atu whenua, ka kitea pea e koe e hokona ana i raro i ngā ingoa pēnei i a Procoralan, Coralan, ētahi atu ingoa waitohu ā-rohe rānei.

Ahakoa te ingoa waitohu, ko nga momo katoa o te ivabradine kei roto ano te whakauru kaha me te mahi i runga i te huarahi kotahi. Ko nga rereketanga nui pea kei roto i te ahua o te papa, nga kaha e waatea ana, etahi atu whakauru kore kaha ranei e whakamahia ana i roto i te hanganga.

Ka taea e to whare rongoā te whakakapi i tetahi waitohu mo tetahi atu i runga i te waatea, i te inihua ranei. He haumaru tonu tenei, engari ki te kite koe i nga huringa o to ahua i muri i te huri i nga waitohu, whakamohio atu ki to taakuta. Ka taea e ratou te awhina ki te whakatau mena kei te hono te huringa ki te hanganga rereke, ki te whai wāhi ranei etahi atu mea.

Nga Whakakapinga Ivabradine

Ki te kore e pai te ivabradine ki a koe, ki te kore ranei e pai te whakahaere i to reiti ngakau, he maha nga rongoā ke atu ka taea te awhina i te whakahaere i to mate. Ka whakaarohia e to taakuta to ahuatanga motuhake, etahi atu mate hauora, me nga whaainga maimoatanga i te wa e kowhiri ana i te whiringa pai.

Ko nga aukati beta te nuinga o te maimoatanga tuatahi mo te whakahaere i te reiti ngakau, kei roto ko nga rongoā penei i te metoprolol, carvedilol, me te bisoprolol. Ehara i te mea ka whakaroa noa enei rongoā i to reiti ngakau, engari ka whakaiti ano i te toto toto me te kaha ki te whakapakari i te kaha papu o to ngakau i te wa.

Ko nga aukati hongere konupūmā, pēnei i te diltiazem, i te verapamil ranei, he momo rongoā ke atu ka taea te whakaroa i te reiti ngakau. Ka mahi enei ma te pa ki te nekehanga konupūmā i roto i o pūtau ngakau, e awe ana i te reiti ngakau me te kaha o nga kirimana.

Mo te hunga e mate ana i te ngakau, ka whakamahia pea nga aukati ACE, ARB ranei (nga aukati kaiwhiwhi angiotensin) i te taha, i te waahi ranei o te ivabradine. Ka awhina enei rongoā i to ngakau kia pai ake te mahi ma te whakaiti i te kawenga mahi me te whakapai ake i te rere toto.

Ka tohutohu pea to taakuta i nga huinga rongoā rereke hei whakatutuki i te mana whakahaere i te reiti ngakau i te wa e whakaiti ana i nga paanga taha. Ko te mea nui ko te kimi i te taurite tika mo o hiahia takitahi me te mana hauora.

He pai ake te Ivabradine i te Metoprolol?

He rongoā whakaheke i te tere o te ngākau e whai hua ana a Ivabradine me te metoprolol, engari he rerekē te mahi, ā, he painga motuhake ō rāua i runga i tō āhuatanga. Kāore tētahi i te pai ake i tētahi, engari kei runga i ō hiahia hauora me te pai o tō whakawhanaunga ki ia rongoā te whiriwhiri.

He aukati beta te metoprolol, kua whakamahia mō ngā tau tekau, ā, he nui ngā rangahau e tautoko ana i tōna whakamahinga mō te ngoikoretanga o te ngākau me ētahi atu āhuatanga o te ngākau. Kāore anake e whakaiti ana i te tere o te ngākau, engari e whakaiti ana i te pēhanga toto, ā, ka taea te whakapai ake i te mahi o te ngākau i te wā. Heoi, ka pā te ngenge, te makariri o ngā ringa me ngā waewae, te uaua rānei ki te manawa ki ētahi tāngata e whakamahi ana i ngā aukati beta.

He painga motuhake a Ivabradine nā te mea e aro ana ki te tere o te ngākau me te kore e pā nui ki te pēhanga toto, ki te manawa rānei. Nō reira he mea nui mō ngā tāngata e hiahia ana ki te whakahaere i te tere o te ngākau engari kāore e taea te whakawhanaunga ki ngā pānga whakaheke i te pēhanga toto o ngā aukati beta, mō te hunga rānei kua iti te pēhanga toto.

I te nuinga o ngā wā, ka whakamahi ngā tākuta i te ivabradine me te metoprolol ngātahi, kaua ki te whiriwhiri i tētahi i runga i tētahi. Mā tēnei huinga ka pai ake te whakahaere i te tere o te ngākau i te rongoā kotahi, me te tuku i ngā horopeta iti ake o ia rongoā, ka whakaiti pea i ngā pānga taha.

Ka whakaaro tō tākuta ki ngā mea pēnei i tō pēhanga toto, te mahi o te whatukuhu, te āhua o te manawa, me ētahi atu rongoā i te wā e whakatau ana i te huarahi pai mōu. Ko te whiringa

Āe, he pai te ivabradine mō te hunga mate huka, ā, he painga pea ki ētahi atu rongoā mō te ngākau. Kāore i rite ki ngā beta-blockers, e taea ana te huna i ngā tohu whakatūpato o te huka toto iti, me te uaua ake te whakahaere i te mate huka, kāore te ivabradine e pokanoa ki te kaha o tō tinana ki te mōhio, ki te urupare rānei ki ngā huringa o te huka toto.

He nui ake te tūponotanga o te hunga mate huka ki ngā raruraru o te ngākau, nō reira he mea nui te whakahaere i te tere o te ngākau. Ka taea e te Ivabradine te āwhina ki te whakaiti i te pēhanga ki tō ngākau me te kore e uaua ake te whakahaere i tō mate huka. Heoi anō, ka aroturukihia koe e tō tākuta, nā te mea ka pā te mate huka ki te āhua o tō tinana ki te tukatuka i ngā rongoā.

Mēnā he mate huka hoki tō, me ngā raruraru o te ngākau, me mōhio ō kaiwhakarato hauora katoa ki ngā rongoā katoa e whakamahia ana e koe. Mā tēnei ka mōhio ai koe kei te pai te mahi tahi o tō rongoā mate huka me ngā rongoā mō te ngākau.

Me pēhea te mahi mēnā i whakamahi au i te nui rawa o te Ivabradine?

Mēnā i inu koe i te nui rawa o te ivabradine, whakapā atu ki tō tākuta, ki te pokapū whakahaere paitini rānei, ahakoa kei te pai koe. Ko te inu i te nui rawa ka heke te tere o tō ngākau ki te taumata kino, he mea nui tēnei, ā, me āwhina hauora.

Ngā tohu pea i inu koe i te nui rawa ko te mōrearea, te māmā, te ngoikore rānei, te wheako i te tere o te ngākau puhoi, te uaua rānei ki te manawa. Mēnā ka pā tētahi o ēnei tohu ki a koe, rapua he āwhina hauora ohorere tonu.

I te wā e tatari ana koe mō te āwhina hauora, ngana ki te noho marino, me te noho, te takoto rānei i tētahi tūnga pai. Kaua e ngana ki te whakapōkae i a koe anō mēnā kāore i tohutohutia e tētahi kaiwhakarato hauora. Puritia te pounamu rongoā ki a koe hei whakaatu ki ngā kaimahi hauora te aha me te nui i inu koe.

Hei ārai i te horomanga nui ohorere, whakaarohia te whakamahi i tētahi kaiwhakarite pire, te whakatakoto rānei i ngā whakamaharatanga waea mō tō hōtaka rongoā. Mā tēnei e āwhina i a koe ki te aroturuki mēnā kua tango kē koe i tō horopeta mō te rā.

Me pēhea taku mahi mēnā ka ngaro i ahau tētahi horopeta o te Ivabradine?

Mēnā ka ngaro i a koe tētahi horopeta o te ivabradine, tangohia i te wā e mahara ana koe, engari mehemea kei raro iho i te 6 hāora mai i te wā i whakaritea ai tō horopeta. Mēnā kua roa ake i te 6 hāora, mēnā rānei kua tata te wā mō tō horopeta e whai ake nei, waiho te horopeta i ngaro, ka haere tonu ki tō hōtaka auau.

Kaua rawa e tango e rua ngā horopeta i te wā kotahi hei utu mō tētahi horopeta i ngaro. Mā tēnei ka heke rawa te tere o tō ngākau, he mea mōrearea tēnei. He pai ake te ngaro i tētahi horopeta i te tūpono ki te tango i te nui rawa o te rongoā i te wā kotahi.

Mēnā he maha ngā wā ka wareware koe i ngā horopeta, kōrerohia ki tō tākuta mō ngā rautaki hei āwhina i a koe ki te mahara. Ka tūtohu pea rātou ki te whakatakoto i ngā whakaoho waea, te whakamahi i tētahi kaiwhakarite pire, te tango rānei i tō rongoā i te wā kotahi me tētahi atu mahi o ia rā pēnei i ngā kai.

Ko te ngaro i tētahi horopeta i ētahi wā kāore i te mōrearea, engari ngana ki te tango i te ivabradine i runga i te rite tonu ki te mea i whakaritea. Mā te horopeta auau e āwhina ki te pupuri i ngā taumata pūmau o te rongoā i tō tinana, e whakarato ana i te mana whakahaere i te tere o te ngākau.

Āhea ka taea e au te whakamutu i te tango i te Ivabradine?

Me whakamutu anake e koe te tango i te ivabradine i raro i te ārahitanga me te tirotiro a tō tākuta. Ahakoa kei te pai ake koe, ko te whakamutu ohorere ka piki tere te tere o tō ngākau, ka kino pea ō tohumate, ka pēhi rānei i tō ngākau.

Ka hiahia tō tākuta ki te whakaiti i tō horopeta i te wā, kaua ki te whakamutu i te katoa i te wā kotahi. Mā tēnei tukanga, e kīia ana ko te whakaiti, e āhei ai tō ngākau ki te whakatika pōturi ki te huringa rongoā me te whakaiti i te tūpono o ngā pānga rebound.

Ko te whakatau ki te whakamutu i te ivabradine e whakawhirinaki ana ki ētahi mea, pēnei i te pai o te whakahaere i tō mate ngakau, mehemea kei te tango koe i ētahi atu rongoā ngakau, me tō āhua hauora whānui. Ko ētahi tāngata ka hiahia ki te tango i te rongoā mō te wā roa, engari ko ētahi atu ka taea te whakamutu mehemea ka pai ake tō rātou āhua.

He mea nui ngā tūpono whai muri i te tākuta mō te whakatau i te wā me te pēhea te whakatika, te whakamutu rānei i tō rongoā. Ka aroturukihia e rātou tō reiti ngakau, ngā tohumate, me te mahi ngakau whānui kia whakatau i te whakatau pai mō tō hauora.

Ka taea e au te whakakori tinana i te wā e tango ana i te Ivabradine?

Āe, ka taea e koe te whakakori tinana i te wā e tango ana i te ivabradine, ā, ko te mea pono, ka akiakihia te mahi tinana tika hei wāhanga o tō mahere hauora ngakau whānui. Heoi, ka pā te rongoā ki te pēhea te urupare o tō reiti ngakau ki te whakakori tinana, nō reira me whakatika e koe ō tūmanako me tō huarahi.

Mai i te mea ka whakaheke te ivabradine i tō reiti ngakau i te okiokinga, ka iti ake hoki tō reiti ngakau i te wā e whakakori tinana ana i mua i te tīmatanga o te rongoā. Ko te tikanga, kāore e taea e koe te whakawhirinaki ki ngā whāinga reiti ngakau tuku iho mō te kaha whakakori tinana. Engari, arotahi ki te pēhea tō āhua i te wā e mahi ana - me taea e koe te whakawhiti kōrero i te wā e whakakori tinana ana.

Tīmatahia he hōtaka whakakori tinana hou i te wātea, me te aro ki te pēhea te urupare o tō tinana. Mēnā ka pā mai te pōkaunga manawa, te mamae o te uma, te whāwhā, te tino ngenge rānei i te wā e whakakori tinana ana, whakamutua te mahi me te kōrero ki tō tākuta.

Ka taea e tō kaiwhakarato hauora te āwhina i a koe ki te whakawhanake i tētahi mahere whakakori tinana tika e whakaaro ana ki tō āhua ngakau, te taumata whakapakari tinana o nāianei, me ngā pānga o te ivabradine. Ka tūtohu pea rātou ki te mahi tahi me tētahi hōtaka whakahou ngakau mēnā he ngoikore tō ngakau, ētahi atu rānei raruraru ngakau nui.