He aha te Macitentan me te Tadalafil: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

Ko te Macitentan me te tadalafil he rongoā whakakotahi e āwhina ana ki te rongoā i te pēhanga toto i roto i ngā pūkahukahu (PAH), he mate nui ka piki te pēhanga toto i roto i ō pūkahukahu ki te taumata mōrearea. Ko tēnei huarahi rongoā rua e whakakotahi ana i ngā rongoā rerekē e rua e mahi ngātahi ana ki te whakatuwhera i ō oko toto pūkahukahu me te whakapai ake i te rere o te toto.

Ki te whai koe i te PAH, ka whāiti, ka mārō ngā uaua iti i roto i ō pūkahukahu, ka kaha ake te mahi o tō ngākau ki te pōmpu i te toto mā roto i a rātou. Ka whakatika tēnei rongoā whakakotahi i te raruraru mai i ngā koki e rua, e hoatu ana ki a koe he huarahi rongoā whānui ake i te whakamahi i tētahi rongoā anake.

He aha te Macitentan me te Tadalafil?

E whakakotahi ana tēnei rongoā i ngā whakauru kaha e rua e whai ana i ngā ara rerekē i roto i tō tinana ki te rongoā i te pēhanga toto i roto i ngā pūkahukahu. Ka aukati te Macitentan i ētahi kaiwhakawhiwhi e whāiti ana i ngā oko toto, i te wā e āwhina ana te tadalafil ki te whakangāwari i te uaua maeneene i roto i ō pakitara oko toto.

Ka puta mai te whakakotahitanga hei papa rongoā waha ka tangohia e koe mā te waha, te tikanga kotahi i te rā. Ka tohua tēnei e tō tākuta i te wā e kore ai te rongoā kotahi e whai hua ana, i te wā rānei e hiahia ana tō āhuatanga ki tētahi huarahi rongoā kaha ake mai i te tīmatanga.

Kua akona ngā whakauru e rua i runga i ō rātou ake me te tahi, e whakaatu ana ka whai hua ake te whakakotahitanga i tētahi rongoā anake mō te whakahaere i ngā tohumate PAH me te whakaroa i te haere o te mate.

He aha te Macitentan me te Tadalafil e whakamahia ana mō?

I hangaia tēnei rongoā whakakotahi ki te rongoā i te pēhanga toto i roto i ngā pūkahukahu, he āhuatanga onge engari he nui e pā ana ki ngā uaua i roto i ō pūkahukahu. Ka uaua te PAH ki te rere o te toto mā roto i ō pūkahukahu, e whakatakoto ana i te pēhanga ki te taha matau o tō ngākau.

Ka tohua pea tēnei huinga rongoā e tō tākuta mēnā kei te pā koe i ngā tohumate pēnei i te pōkae manawa i ngā mahi o ia rā, te mamae o te uma, te ngenge, te pūhi rānei i ō waewae me ō pūwaha. Ka puta ēnei tohumate nā te mea kei te mahi nui tō ngākau ki te pūhi toto mā ngā uaua pūkahukahu kua whāiti.

Ka āwhina te rongoā ki te whakapai ake i tō kaha ki te whakakorikori tinana, te tikanga ka taea e koe te haere tawhiti atu, me te mahi i ētahi atu mahi me te kore e pōkae manawa. Ka āwhina hoki ki te whakaroa i te haere whakamua o te PAH, ka whakaiti pea i tō tūponotanga ki te hōhipera me ētahi atu raruraru nui.

Me pēhea te mahi a Macitentan me Tadalafil?

E mahi ana tēnei huinga rongoā mā ngā tikanga e rua hei whakarato i te rongoā whānui mō tō pēhanga toto i roto i ngā uaua pūkahukahu. Whakaarohia me te whakatika i te raruraru mai i ngā koki maha kia pai ake ai ngā hua ki a koe.

Ka aukati a Macitentan i ngā kaiwhakawhiwhi endothelin i roto i ō uaua toto. He matū te Endothelin e pā ana ki te whakakaha me te whāiti o ngā uaua toto, nā reira mā te aukati i ēnei kaiwhakawhiwhi, ka āwhina a macitentan ki te pupuri i ō uaua pūkahukahu kia tuwhera ake, kia whakangāwari.

E mahi ana a Tadalafil mā te aukati i tētahi enzyme e kīia ana ko PDE5, e arahi ana ki te piki ake o ngā taumata o tētahi matū e āwhina ana i ngā uaua toto kia whakangāwari. Ka waihanga tēnei i tētahi rere toto māeneene ake mā ngā uaua pūkahukahu me te whakaiti i te pēhanga e pā ana ki tō ngākau.

Tahi, ka waihanga ēnei rongoā i tētahi pānga synergistic, te tikanga e pai ake ana te mahi tahi i tō rātou mahi motuhake. E whakaarohia ana tēnei huarahi huinga he kaha ngawari, ā, e rāhui ana mō ngā tūroro e hiahia ana ki te rongoā whānui ake.

Me pēhea taku tango i te Macitentan me te Tadalafil?

Tangohia tēnei rongoā kia rite ki te tohutohu a tō tākuta, te tikanga kotahi i te rā me te kai, me te kore rānei he kai. Ka taea e koe te tango ki te wai, ā, kāore he mea nui mēnā ka kai koe i mua, i muri rānei i te tango i tō horopeta.

Whakamātauria te tango i tō rongoā i te wā kotahi i ia rā kia mau tonu ai ngā taumata i roto i tō toto. Mā tēnei e āwhina ai te whakarite i te rongoā rite tonu mō tō pūkahukahu arterial hypertension puta noa i te rā.

Horomia te papa katoa, kaua e kuru, e whati, e ngaungau rānei. Ki te uaua koe ki te horomia i ngā pire, kōrerohia ki tō tākuta mō ētahi atu kōwhiringa, tikanga rānei e āwhina ai.

Kaua e mutu te tango i tēnei rongoā ohorere, ahakoa kei te pai koe. He mate tawhito te PAH e hiahia ana ki te rongoā tonu, ā, ko te whakamutu ohorere ka tere te kino o ō tohumate.

Kia Pēhea te Roa e Tango Ana ahau i te Macitentan me te Tadalafil?

Ko te tikanga he rongoā wā-roa tēnei me tango tonu e koe i te wā e āwhina ana ki te whakahaere i tō pūkahukahu arterial hypertension. He mate tawhito te PAH e kore e ngaro noa, nō reira he mea tika te rongoā tonu.

Ka aroturukihia e tō tākuta tō urupare ki te rongoā mā ngā arowhai auau, tae atu ki ngā whakamātautau hei ine i tō kaha ki te whakakorikori tinana me te mahi o te ngākau. Mā ēnei tūpono e āwhina ai te whakatau mēnā kei te pai te mahi o te rongoā mōu, me mēnā e hiahia ana koe ki te whakatikatika.

Ko ētahi tūroro ka hiahia ki te tango i tēnei huinga mō ngā tau, ā, ko ētahi ka huri ki ētahi atu rongoā i runga i te urupare o tō rātou āhua. Ka whai takitahi tō mahere rongoā i runga i ō hiahia motuhake me te pai o tō manawanui ki te rongoā.

He Aha ngā Pānga taha o te Macitentan me te Tadalafil?

Pērā i ngā rongoā katoa, ka taea e tēnei huinga te pānga taha, ahakoa kāore te katoa e pā ana ki a rātou. Ko te nuinga o ngā pānga taha he mea whakahaere, ā, ka pai ake i te wā e urutau ana tō tinana ki te rongoā.

Anei ngā pānga taha noa ka pā ki a koe i te wā e urutau ana tō tinana ki tēnei rongoā:

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• Te mamae o te upoko, he maha tonu e pai ake ana i muri i nga wiki tuatahi
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• Te whero, te mahana ranei o te kanohi me te kaki
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• Te pupuhi i ou waewae, nga rekereke, nga waewae ranei
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• Te pupuhi o te ihu, te ihu ranei e puru ana
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• Te puku e raruraru ana, te whakapairuaki ranei
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• Te whanoke, ina koa ka tu wawe
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• Te mamae o te tuara, te mamae ranei o nga uaua
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Ko enei paanga taha noa ka iti ake te raruraru i te wa, engari me whakamohio atu ki to taakuta mena ka mau tonu, ka raru ranei i o mahi o ia ra.

Ko etahi paanga taha nui e hiahia ana kia aro mai te rongoa tonu, ahakoa he iti noa iho. Whakapa atu ki to taakuta i tenei wa tonu mena ka pa ki a koe etahi o enei tohu e raruraru ana:

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• Nga huringa ohorere o te tirohanga, te ngaronga ranei o te tirohanga
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• Te ngaronga ohorere o te rongo, te tangi ranei i ou taringa
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• Te mamae o te uma, te ngakau ranei e rere ke ana
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• Te whanoke nui, te ngaro ranei
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• Nga tohu o nga raruraru ate penei i te kowhai o te kiri, o nga kanohi ranei
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• Te poto o te manawa, te kino ranei o te manawa
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• Te whakatika mamae e roa ana neke atu i te 4 haora (mo nga tane)
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He onge enei paanga taha nui, engari he mea nui kia mohio wawe koe ki a ratou kia whiwhi ai koe i te manaaki hauora tika mena e tika ana.

Ko wai e kore e tango Macitentan me Tadalafil?

Ko tenei rongoa whakakotahi kaore i te pai mo te katoa, a ka ata arotakehia e to taakuta to hitori hauora i mua i te whakahau. He maha nga ahuatanga me nga rongoa ka kore e haumaru, ka iti ake ranei te whai hua o tenei maimoatanga.

Kaua koe e tango i tenei rongoa mena kei te whakamahi koe i nga rongoa nitrate mo te mamae o te uma, na te mea ka puta he heke kino o te toto i tenei whakakotahitanga. Kei roto i tenei ko nga nitrates whakahau penei i te nitroglycerin me nga raau taero whakangahau e kiia nei ko

Ko ngā tāngata e mate ana i te ate nui, i ētahi mate ngākau rānei, tērā pea kāore e tika mō tēnei rongoā. Mā tō tākuta e aromatawai te mahi o tō ate me te hauora o tō ngākau i mua i te tīmatanga o tēnei rongoā ki a koe.

Mēnā he hītori tō raru i te tirohanga, te ngaro o te rongo, te pēhanga toto iti rānei, me āta whakatau tō tākuta i ngā painga me ngā tūponotanga i mua i te whakahau i tēnei huinga.

Ngā Ingoa Waitohu o Macitentan me Tadalafil

E wātea ana tēnei rongoā huinga i raro i te ingoa waitohu Opsynvi, koinei te hanganga arumoni tuatahi i whakaaetia mō te rongoā i te pēhanga toto i roto i ngā uaua o te pūkahukahu. Mā te ingoa waitohu e āwhina ki te wehe i tēnei rongoā i ētahi atu rongoā kei roto ēnei kai takitahi.

Tērā pea ka kitea hoki e koe ngā wāhanga takitahi e hokona ana i raro i ngā ingoa waitohu rerekē. E wātea ana te Macitentan hei Opsumit, ā, e mōhiotia ana te tadalafil e ētahi ingoa waitohu, tae atu ki a Cialis me Adcirca.

Me whakamahi tonu i te waitohu me te hanganga motuhake i whakahaua e tō tākuta, nā te mea he rerekē pea te kaha, te tauira tuku rānei o ngā hanganga rerekē, e pā ana ki te pai o te mahi o te rongoā mō tō āhuatanga.

Ngā Kōwhiringa kē mō Macitentan me Tadalafil

He maha ngā rongoā kē e noho ana mō te pēhanga toto i roto i ngā uaua o te pūkahukahu mēnā kāore tēnei huinga e tika ana mōu, kāore rānei e whai hua ana ki te whakahaere i ngā tohumate. Ka taea e tō tākuta te āwhina ki te whakatau ko tēhea kōwhiringa pea te pai mō tō āhuatanga motuhake.

Ko ētahi atu rongoā waha mō te PAH ko te bosentan, te ambrisentan, te sildenafil, me te riociguat. E mahi ana ia o ēnei mā ngā ara rerekē hei āwhina i te whakatuwhera i ō uaua toto o te pūkahukahu me te whakaiti i te pēhanga o te pūkahukahu.

Mō ngā keehi nui ake, tērā pea ka whakaaro tō tākuta ki ngā rongoā e ngōhia ana, e werohia ana rānei, pēnei i te epoprostenol, te treprostinil, te iloprost rānei. Ko ēnei rongoā e rāhui ana mō ngā tūroro e nui ake ana te mate, mō te hunga rānei kāore e pai te urupare ki ngā rongoā waha.

He pai ana etahi tūroro i te rongoā whakakotahi mā te whakamahi i ngā momo rongoā rerekē ngātahi, ā, he pai ētahi atu ki te rongoā whaiaronga e tāpirihia ana ngā rongoā i tētahi wā i runga i te urupare.

He Pai Anei te Macitentan me te Tadalafil i te Sildenafil?

He kaha ō ngā huarahi rongoā e rua, ā, ka whakawhirinaki te whiriwhiri i waenga i a rātou ki tō āhuatanga hauora takitahi me ngā whāinga rongoā. E tuku ana te whakakotahitanga o Macitentan me te tadalafil i te rongoā ara-rua, i te wā e mahi ana te sildenafil mā tētahi tikanga kotahi e rite ana ki te tadalafil.

Ka taea e te huarahi whakakotahi te whakarato i te rongoā whānui ake nā te mea e aro ana ki ngā ara maha e whai wāhi ana ki te PAH. E whakaatu ana ētahi rangahau ka nui ake te whai hua o te rongoā rua i te rongoā rongoā kotahi mō ētahi tūroro.

Heoi anō, kua roa te sildenafil e whakamahia ana mō te rongoā PAH, ā, he nui ngā raraunga haumaru. Ka pai pea mō ngā tūroro e hiahia ana ki tētahi huarahi rongoā māmā ake, ki te hunga rānei he āhuatanga hauora motuhake e kore ai e tika te rongoā whakakotahi.

Ka whakaaro tō tākuta i ngā āhuatanga pēnei i te kaha o tō mate, ētahi atu āhuatanga hauora, ngā rongoā o nāianei, me ngā whāinga rongoā i te wā e whakatau ana ko tehea kōwhiringa te mea pai mōu.

Ngā Pātai e Pātai pinepine ana mō Macitentan me Tadalafil

He Haumaru Anei te Macitentan me te Tadalafil mō te Mate Ngākau?

Ka taea te whakamahi i tēnei whakakotahitanga ki ngā tāngata e whai ana i ētahi momo mate ngākau, engari me mātakitaki me te arotake mā te tākuta. I te mea e pā ana te PAH ki te ngākau, ka āwhina te rongoā i te āhuatanga taketake ki te whakapai ake i te mahi ngākau.

Heoi anō, ki te whai koe i te ngoikore ngākau nui, te whakaeke ngākau tata nei, ētahi rānei raruraru manawataki ngākau, ka hiahia pea tō tākuta ki te whakatika i tō mahere rongoā, ki te whakaaro rānei ki ētahi atu rongoā. Ka pā te rongoā ki te pēhanga toto me te manawataki ngākau, nō reira he mea nui te mātakitaki ngākau auau.

Ka mahi tahi tō tākuta ngākau me te tohunga PAH ki te whakarite kia tika te whakahaere i tō mahere maimoatanga i tō pūkahukahu me ngā mate ngākau e huna ana, me te haumaru hoki.

Me aha au ki te whakamahi au i te nui rawa o te Macitentan me te Tadalafil?

Mēnā ka inu koe i te nui atu i te horopeta i whakaritea, whakapā atu ki tō tākuta, ki te pokapū whakahaere paitini rānei i te wā tonu, ahakoa kei te pai koe. Ka taea e te horopeta nui te heke kino o te toto me ētahi atu raruraru nui.

Ko ngā tohu o te nui rawa o te inu ka uru pea ki te whanoke nui, te ngaro o te mahara, te whakapairuaki, te huringa rānei o te tirohanga. Kaua e ngana ki te rongoā i ēnei tohu i a koe anō, kaua hoki e tatari kia pai ake anō.

I te wā e karanga ana koe ki te tono awhina, kia wātea tō pounamu rongoā kia taea ai e koe te tuku mōhiohio motuhake mō te aha i inu ai koe me te nui. Mā tēnei e āwhina ai ngā tākuta ki te tuku tohutohu tika ki a koe.

Me aha au ki te ngaro au i te horopeta o te Macitentan me te Tadalafil?

Mēnā ka ngaro koe i te horopeta, inumia i te wā e mahara ana koe, ki te kore e tata ana te wā mō tō horopeta e whai ake nei. I tērā take, waiho te horopeta i ngaro, ka haere tonu ki tō mahere horopeta auau.

Kaua rawa e inu i ngā horopeta e rua i te wā kotahi hei utu mō te horopeta i ngaro, nā te mea ka piki ake tō tūponotanga ki ngā pānga taha me ngā raruraru. Ka taea e te horopeta rua te heke kino o te toto.

Mēnā he maha ngā wā e wareware ana koe ki ngā horopeta, whakaarohia te whakatakoto i ngā whakamaharatanga waea, te whakamahi rānei i tētahi kaiwhakarite pire hei āwhina i a koe kia noho i runga i te mahere maimoatanga.

Āhea e taea ai e au te whakamutu i te inu i te Macitentan me te Tadalafil?

Me whakamutu anake e koe te inu i tēnei rongoā i raro i te tirotiro tika a tō tākuta, nā te mea he mate tawhito te PAH e hiahia ana ki te maimoatanga tonu. Ko te whakamutu ohorere ka taea e ō tohu te hoki mai, te kino ake rānei.

Ka whakaaro pea tō tākuta ki te whakaiti, ki te whakamutu rānei i te rongoā mena ka pā mai ngā pānga taha nui e kore e taea te whakahaere, ki te huri nui rānei tō āhua. Ko ngā huringa ki tō mahere rongoā me mahi pōturi, me te mātakitaki tata.

Ahakoa te pai o tō tū, me inu tonu i tō rongoā i te mea i whakaritea. Ko te pai ake o ō tohumate e whakaatu ana kei te whai hua te rongoā, ehara i te mea kāore anō koe e hiahia ana.

Ka taea e au te inu waipiro i te wā e inu ana au i te Macitentan me te Tadalafil?

Me whakawhāiti koe i te inu waipiro i te wā e inu ana koe i tēnei rongoā, nā te mea ka taea e te waipiro me te rongoā te whakaheke i te toto. Mā te whakakotahi i a rāua ka piki ake pea tō tūponotanga ki te whai i te kirika, te ngaro o te mahara, ētahi atu pānga taha rānei.

Mēnā ka whiriwhiria e koe te inu i ētahi wā, me mahi i te āhua tika, me te aro ki te āhua o tō tū. Me tīmata ki ngā rahinga iti kia kite i te āhua o tō tinana, me te karo i te inu mēnā kei te whai kirika kē koe, he iti rānei te toto.

Kōrero ki tō tākuta mō te nui o te waipiro, mēnā he mea, e haumaru ana mōu i runga i tō hauora whānui me te urupare ki te rongoā.