He aha te Pamidronate: Ngā Whakamahinga, te Inenga, ngā Pānga taha, me ētahi atu mea

He rongoā whakahau a Pamidronate e tukuna ana mā te IV (intravenous) infusion hei āwhina i te whakakaha i ngā kōiwi me te whakahaere i ētahi āhuatanga e pā ana ki ngā kōiwi. No tētahi rōpū rongoā e kīia ana ko bisphosphonates, e mahi ana mā te whakaroa i ngā pūtau e wawahi ana i te kiko kōiwi.

Mēnā kua tūtohu tō tākuta i te pamidronate, kei te pōhēhē pea koe he aha te mea e tūmanakohia ana mai i tēnei maimoatanga. Ko te nuinga o te wā ka whakamahia tēnei rongoā i te wā kāore anō ētahi atu maimoatanga kōiwi i whai hua, i te wā rānei e hiahia ana koe ki te whakamarumaru kōiwi kaha ake nā te āhuatanga hauora motuhake.

He aha te Pamidronate?

He rongoā whakakaha kōiwi a Pamidronate ka taea anake te tuku mā te uaua i tō ringa. Kāore i rite ki ngā pire ka tangohia e koe i te kāinga, me haere tēnei rongoā ki te hōhipera, ki te hōhipera rānei mō te whakahaere.

Whakaarohia ō kōiwi e hanga tonu ana i a rātou anō. E wawahi ana ētahi pūtau i ngā kōiwi tawhito i te wā e hanga ana ētahi atu i ngā kōiwi hou. Ka āwhina a Pamidronate ki te whakatika i tēnei taurite ki te hanga kōiwi kaha ake, hauora ake mā te whakaroa i te tukanga wawahi.

Ka noho te rongoā i roto i tō pūnaha mō ngā wiki ki ngā marama i muri i ia infusion, koinei te take kāore koe e hiahia ana i te nuinga o te wā. Ko te nuinga o te tangata ka whiwhi maimoatanga ia wiki torutoru, ia marama rānei, i runga i tō rātou āhuatanga motuhake.

He aha te Pamidronate e whakamahia ana mō?

Ko te mea nui e whakamahia ana a Pamidronate ki te rongoā i ngā taumata konupūmā tiketike i roto i te toto me ētahi raruraru kōiwi e pā ana ki te mate pukupuku. Ka whakahau pea tō tākuta i tēnei rongoā mēnā he hypercalcemia tōu, he āhuatanga ka piki te taumata konupūmā ki te taumata mōrearea.

He mea noa hoki te whakamahi i te rongoā mō te hunga e mate pukupuku ana kua horahia ki ngā kōiwi, inā koa mai i te mate pukupuku uma, te mate pukupuku pūkahukahu, te myeloma maha rānei. I ēnei wā, ka āwhina i te aukati i ngā whati kōiwi me te whakaiti i te mamae kōiwi.

I tua atu, ka taea e te pamidronate te rongoa i te mate o Paget, he mate e tipu ana nga wheua ki te rahi me te ngoikore. Ka whakamahia hoki e etahi taakuta mo te osteoporosis nui i te wa kaore ano etahi atu rongoa i pai.

Me pehea te mahi a Pamidronate?

E kiia ana ko Pamidronate he rongoa wheua kaha, e mahi ana ma te aro ki nga pūtau motuhake i roto i ou wheua. Ka piri ki te kiko wheua me te aukati i te mahi o te osteoclasts, koinei nga pūtau e kawenga ana mo te wawahi i te wheua.

Ka puhoi enei pūtau wawahi wheua, ka nui ake te wa o ou wheua ki te hanga ano me te whakakaha i a ratou ano. Ka awhina tenei mahi ki te whakaiti i te nui o te konupūmā e tukuna ana ki roto i to toto me te kaha ake o ou wheua ki te whati.

Kaore te rongoa e mahi tonu. Ka timata pea koe ki te kite i nga whakapainga i roto i te mamae wheua, i nga taumata konupūmā ranei i roto i nga ra torutoru ki nga wiki i muri i to werohanga tuatahi. Ka roa pea nga marama ki te whakawhanake i nga paanga whakakaha wheua.

Me pehea taku tango i te Pamidronate?

Ka tukuna tonu te Pamidronate hei werohanga IV puhoi i roto i te taiao rongoa, kaua rawa hei pire, hei werohanga ranei. Ko te tikanga ka roa te 2 ki te 4 haora, a me noho pai koe i tenei wa.

I mua i to werohanga, he mea nui ki te inu i te wai nui ki te kore to taakuta e korero ki a koe. Ko te pai o te wai ka awhina i te tiaki i ou whatukuhu me te whakaiti i te tupono o nga paanga taha. Ka taea e koe te kai noa i mua me muri i te maimoatanga.

I te wa o te werohanga, ka maturuturu te rongoa ki roto i to uaua ma te ngongo iti. Ka ata tirotiro te nēhi i a koe, ka tirotiro pea i to toto me te pāmahana i ia wa. Ka taea e koe te panui, te whakamahi i to waea, te okioki ranei i te wa o te maimoatanga.

I muri i te werohanga, ka taea e koe te hoki ki o mahi noa tonu. Heoi, ka ngenge etahi tangata, ka pa ranei ki nga tohu rewharewha ngawari mo te ra, e rua ranei i muri mai, ina koa i muri i te maimoatanga tuatahi.

Kia pehea te roa e tango ana ahau i te Pamidronate?

He rerekē te roa o te maimoatanga pamidronate i runga i tō āhuatanga me te pai o tō urupare ki te rongoā. Ko ētahi tāngata e hiahia ana kia kotahi, kia rua rānei ngā whakaurunga, engari ko ētahi e haere tonu ana te maimoatanga mō ngā marama, ngā tau rānei.

Mō ngā taumata konupūmā tiketike, tērā pea ka hiahia koe kia kotahi anake te whakaurunga hei whakahoki i tō konupūmā ki te noa. Heoi anō, ki te mau tonu te āhuatanga i raro, tērā pea ka hiahia koe ki ētahi atu maimoatanga i ia wiki, i ia marama rānei.

Mēnā he raruraru tō iwi e pā ana ki te mate pukupuku, tērā pea ka tūtohu tō tākuta kia haere tonu te maimoatanga i te wā e whai hua ana, ā, e pai ana tō tū. Ko te whāinga he ārai i ngā raruraru o te iwi me te pupuri i tō kounga o te oranga.

Ka aroturuki tō tākuta i tō urupare i ngā wā katoa mā ngā whakamātautau toto me ngā karapa iwi. Ka whakatika rātou i tō hōtaka maimoatanga i runga i te urupare o ō iwi me te mea kei te pā tō tū ki ētahi pānga taha.

He aha ngā Pānga Taha o te Pamidronate?

Pērā i ngā rongoā katoa, ka taea e te pamidronate te pānga taha, ahakoa kāore te katoa e pā ana. Ko ngā pānga taha tino noa he ngawari, he wā poto noa iho.

He maha ngā tāngata e pā ana ki ngā tohumate pērā i te rewharewha i muri i tā rātou whakaurunga tuatahi, he tohu tēnei kei te mahi te rongoā. Anei ngā pānga taha tino noa ka kitea e koe:

• Kirika me te mākākā, te tikanga ka tīmata i roto i te 24 hāora i muri i te maimoatanga
• Ngā mamae uaua me te mamae tahi e rite ana ki te rewharewha
• Te ngenge, te pōuri rānei i te wā e rua rānei ngā rā
• Te whakapairuaki, te pōuri puku ngawari rānei
• Te mamae o te upoko e roa ana te wā e rua rānei ngā rā
• Te mamae, te riri rānei i te wāhi IV

Ko ēnei pānga taha noa te tikanga ka pai ake i roto i te 48 hāora, ā, he iti ake te kaha i ngā maimoatanga i muri mai. Ko te tango i ngā rongoā mamae i runga i te kaute pērā i te acetaminophen ka āwhina i te whakahaere i te raruraru.

Ka puta ngā pānga taha iti noa iho engari he nui ake te kino, ā, me whakapā atu koe ki tō tākuta mēnā ka pā tō tū ki ētahi o ēnei:

• Te mamae nui o te kauae, te uaua ranei ki te whakatuwhera i to waha
• He mamae hou, he rereke ranei i te huha, i te hope, i te taha o te taha
• Ngā huringa o tō tirohanga, te mamae ranei o te kanohi
• Te whakapairuaki tonu, te ruaki, te ngaro ranei o te hiahia
• Te ngenge nui kāore e pai ake i muri i ētahi rā
• Ngā tohu o te iti o te konupūmā pēnei i te pāwera uaua, te ngau ranei

Ko ngā pānga taha onge engari he nui te osteonecrosis o te kauae (te mate o te wheua i te kauae) me ngā whati wheua huha rereke. He mea noa ēnei raruraru, engari he mea nui kia mātakitaki, ina koa ki te whakamahi wā roa.

Ko wai kāore e tika kia tango Pamidronate?

Kāore a Pamidronate e tika ana mō te katoa, ā, ka āta arotake tō tākuta i tō hītori hauora i mua i te whakahau. Kāore koe e whiwhi i tēnei rongoā mēnā he mate tākihi nui tōu, he pāwera ranei ki ngā bisphosphonates.

Kāore ngā wāhine hapū, ngā wāhine e whāngai ana i te ū e whakamahi i te pamidronate, nā te mea ka pā kino ki te pēpi e tipu ana. Ka noho te rongoā ki ō wheua mō ngā tau, nō reira me kōrero tahi ngā wāhine ka hapū pea ki tō rātou tākuta.

Ko ngā tāngata e raru ana i ētahi raruraru niho, e whakamahere ana rānei i ngā tikanga niho, tērā pea me whakaroa te maimoatanga. Tērā pea ka tūtohu tō tākuta kia kite i te tākuta niho i mua i te tīmatanga o te pamidronate, ina koa me tango niho koe, me te pokanga waha ranei.

Mēnā he iti te konupūmā i a koe, he raruraru manawa, kei te tango rongoā rānei koe, me mātakitaki tata atu tō tākuta i a koe, me whakatika rānei i tō mahere maimoatanga.

Ngā Ingoa Waitohu Pamidronate

Kei te wātea a Pamidronate i raro i te ingoa waitohu Aredia i te United States. Tērā pea ka kite koe i te ingoa whānui, pamidronate disodium.

He maha ngā kamupene rongoā e hanga ana i te rongoā, engari ko te whakauru kaha me ngā pānga ka noho rite tonu ahakoa te waitohu. Mā tō hōhipera, tō rānei whare rongoā haumanu e whakatau ko tēhea putanga ka whiwhi koe.

He pai pea etahi mahere inihua ki etahi kaihanga, engari kaua tenei e pa ki te kounga o to maimoatanga. Ko te mea nui ko te whiwhi koe i te horopeta tika o te pamidronate mo to mate.

Ētahi Atu Kōwhiringa mō te Pamidronate

He maha atu ano nga rongoā ka taea te rongoā i ngā mate wheua rite, engari ka kōwhiria e tō tākuta te kōwhiringa pai rawa atu i runga i tō āhuatanga motuhake. Ka whakamahia pea ētahi atu bisphosphonates pēnei i te waikawa zoledronic (Zometa) hei utu mō te pamidronate.

Mō te osteoporosis, ko ngā bisphosphonates waha pēnei i te alendronate (Fosamax) rānei risedronate (Actonel) pea ngā kōwhiringa mēnā ka taea e koe te whakawhiti i ngā pire. Ka tangohia ēnei mā te waha, kaua mā te IV.

Ko ngā rongoā hou pēnei i te denosumab (Prolia) e mahi rerekē ana i ngā bisphosphonates, ā, he pai pea mō ētahi tāngata e kore e taea te tango pamidronate. Ka whakaarohia pea ngā rongoā hormone, ētahi atu rongoā hanga wheua rānei.

Ka whakaarohia e tō tākuta ngā āhuatanga pēnei i tō mahi tākihi, ētahi atu rongoā, me ngā hiahia whaiaro i te wā e kōwhiri ana i te maimoatanga pai rawa atu mō tō hauora wheua.

He Pai Anei te Pamidronate i te WAIKAWA ZOLEDRONIC?

He bisphosphonates whai hua te pamidronate me te waikawa zoledronic, engari he rerekētanga ō rāua e pai ai tētahi ki a koe i tētahi atu. Ko te waikawa zoledronic te mea kaha ake, ā, he iti ake te auau o te hoatutanga.

E 2 ki te 4 haora te roa o ngā whakaurunga pamidronate, i te mea ka taea te hoatu waikawa zoledronic i roto i te 15 ki te 30 meneti. Mā tēnei pea e pai ake ai te waikawa zoledronic mō ētahi tāngata, ahakoa he maimoatanga whai hua rāua.

Ko te kōwhiringa i waenga i ēnei rongoā e pā ana ki tō āhuatanga motuhake, te mahi tākihi, me te pai o tō whakawhiti i ia maimoatanga. He pai ake ētahi tāngata ki tētahi rongoā i tētahi atu i te taha o ngā pānga taha.

Ka whakaarohia e tō tākuta ō āhuatanga takitahi, tae atu ki ētahi atu āhuatanga hauora me ngā rongoā, i te wā e whakatau ana ko wai te bisphosphonate te mea pai rawa atu mōu.

Ngā Pātai Auau mō Pamidronate

He Haumaru a Pamidronate mō te hunga e mate ana i te mate tākihi?

Me tino whakaaro nui ki te pamidronate mō te hunga e raru ana i ngā tākihi. Ka tukatukahia te rongoā mā roto i ō tākihi, nō reira ka piki ake te tūponotanga o ngā pānga taha ki te kore e pai te mahi o ngā tākihi.

Ka tirohia e tō tākuta te mahi o ō tākihi mā ngā whakamātautau toto i mua i ia maimoatanga, ā, ka whakatikatikahia pea tō horopeta, te tere rānei o te rongoā ki te hiahiatia. Ko te hunga e tino mate tākihi ana, kāore e taea te tango pamidronate i runga i te haumaru.

Mēnā he pānga tākihi ngawari, tōna rānei, he pānga āhua, ka hoatu pea e tō tākuta he horopeta iti ake, ka roa rānei te wā o te rongoā hei whakaiti i te pēhanga ki ō tākihi. He mea nui kia nui te wai i mua i te maimoatanga, i muri hoki.

Me aha au mēnā ka whiwhi au i te nui rawa o te Pamidronate?

I te mea ka hoatu te pamidronate i roto i te taiao hauora e whakahaerehia ana, he tino onge te nui rawa o te horopeta. Heoi, mēnā e māharahara ana koe mō te whiwhi i te nui rawa o te rongoā, kōrero tonu ki tō rōpū hauora.

Ko ngā tohu o te whiwhi i te nui rawa o te pamidronate pea ko ngā tohu rite te rewharewha, te hekenga nui o ngā taumata konupūmā, te raru tākihi rānei. Ka āta aroturukihia koe e ngā kaimahi hauora, ā, ka taea e rātou te whakarato i te manaaki tautoko ki te hiahiatia.

Ko te rongo pai, he tino onge te nui rawa o te horopeta pamidronate nā te mea ka āta tatau, ka whakahaerehia te rongoā e ngā tohunga whakangungu. Ka āta tirohia e tō rōpū hauora te horopeta i mua i te tīmatanga o tō rongoā.

Me aha au mēnā ka ngaro au i te horopeta Pamidronate?

Mēnā ka ngaro koe i te rongoā pamidronate kua whakaritea, whakapā atu ki te tari o tō tākuta i te wā e taea ai ki te whakarite anō. Kaua e ngana ki te whakakī i te horopeta i ngaro mā te whiwhi i te rongoā atu i muri mai.

Ko te ngaro i tētahi maimoatanga, kāore i te nuinga o te wā e pā ana ki ngā raruraru tonu, engari he mea nui kia mau tonu tō hōtaka maimoatanga mō ngā hua pai. Ka whakatikatikahia pea e tō tākuta te wā o tō horopeta e whai ake nei i runga i te roa o te wā mai i tō rongoā whakamutunga.

Mena kua ngaro koe i nga maimoatanga maha, tera pea ka hiahia to taakuta ki te tirotiro i o taumata konupūmā toto, i nga tohu wheua ranei i mua i te haere tonu i te rongoa. Ka awhina ratou i a koe ki te hoki ki te ara me to mahere maimoatanga.

Ahea Ka Taea e Au te Kati te Tango Pamidronate?

Ko te whakatau ki te whakamutu i te pamidronate kei runga i to ahuatanga o raro me te pai o to urupare ki te maimoatanga. Kaua rawa e whakamutu i te maimoatanga me te kore e korero tuatahi ki to taakuta.

Mo nga taumata konupūmā tiketike, tera pea ka mutu koe i te wa e hoki ana to konupūmā ki te noa, ka noho pumau. Heoi, ki te mau tonu te take o raro, tera pea ka hiahia koe ki te maimoatanga tonu hei aukati i te pikinga ano o nga taumata konupūmā.

Ko nga tangata e raru ana nga wheua e pa ana ki te mate pukupuku, he maha nga wa e haere tonu ana te maimoatanga i te wa e awhina ana, e pai ana ki a ratou. Ka arotakehia e to taakuta i nga wa katoa mena ka nui tonu nga painga i nga tupono, i nga paanga taha ranei.

Ka Taea e Au te Tango i etahi atu rongoa i te wa e whiwhi ana i te Pamidronate?

Ko te nuinga o nga rongoa ka taea te tango marie me te pamidronate, engari he mea nui ki te korero ki to taakuta mo nga rongoa katoa, taapiri, me nga huaora e tango ana koe. Ko etahi rongoa ka pa ki te pamidronate, ka pa ranei ki to maimoatanga.

Ko nga taapiri konupūmā me nga antacids me tango i nga wa rereke i to whakaurunga pamidronate hei karo i te pokanoa. Ka tohutohu pea to taakuta i te wa tika mo enei taapiri.

Ko nga whakaiti toto, etahi paturopi, me etahi rongoa mate pukupuku ka hiahia pea ki te aroturuki motuhake ina whakamahia ana me te pamidronate. Ka whakarite to roopu hauora i o rongoa kia mohio kei te mahi tahi ratou.