He aha te Selegiline: Ngā Whakamahinga, Ngā Inenga, Ngā Pānga Taha me Ētahi Atu

He rongoā whakahau a Selegiline e āwhina ana ki te whakahaere i ngā tohumate o te mate Parkinson mā te tiaki i te dopamine i roto i tō roro. He rerekē te mahi o tēnei rongoā i ētahi atu rongoā mō te mate Parkinson nā te mea e aukati ana i tētahi enzyme e wawahi ana i te dopamine, te matū roro e hiahia ana koe mō te nekehanga mārie me te ruruku.

Ka whakahau pea tō tākuta i te selegiline i te wā e kore e pai ana tō rongoā Parkinson o nāianei. E kiia ana he rongoā tautoko e āwhina ana ki te whakanui i ngā painga o tō rongoā matua, e whai wāhi pai ana koe i te awatea.

He aha te Selegiline?

No te rōpū rongoā a Selegiline e kiia ana ko MAO-B inhibitors, ko te tikanga e aukati ana i tētahi enzyme motuhake i roto i tō roro e kiia ana ko monoamine oxidase B. Ko tēnei enzyme te tikanga e wawahi ana i te dopamine, engari ki te whai koe i te mate Parkinson, he iti ake te dopamine i a koe i tō hiahia.

Whakaarohia te selegiline hei whakangungu rakau mō tō dopamine e toe ana. Mā te aukati i te enzyme e whakangaro ana i te dopamine, he nui ake te matū roro nui nei e wātea ana hei āwhina i te whakahaere i ō nekehanga me te whakaiti i ngā wiri.

Ka tae mai te rongoā i roto i ngā papa auau me ngā papa e rewa ana i te waha e rewa ana i tō arero. Ka whiriwhiri tō tākuta i te puka pai rawa atu i runga i ō hiahia motuhake me te pai o tō horomia i ngā pire.

He aha te Selegiline e whakamahia ana mō?

Ko te tuatahi, ka whakamahia te Selegiline ki te rongoā i te mate Parkinson, ina koa kāore i te tino whakahaerehia ō tohumate e te levodopa me te carbidopa anake. E āwhina ana ki te whakahaere i ngā tohumate motuka pēnei i te wiri, te mārō, me te nekehanga puhoi e uaua ai ngā mahi o ia rā.

Ka tāpirihia pea e tō tākuta te selegiline ki tō mahere rongoā i te wā e tīmata ana koe ki te wheako i ngā wā

I ētahi wā ka whakahau te tākuta i te selegiline i ngā wā tuatahi o te mate o Parkinson. I ēnei wā, ka āwhina pea te whakaroa i te haere o ngā tohu me te whakaroa i te hiahia mō ngā rongoā kaha ake pērā i te levodopa.

Ka āwhina hoki te rongoā ki te whakaiti i ngā huringa i roto i ō tohu i te roanga o te rā. He tokomaha ngā tāngata e mate ana i te mate o Parkinson e kite ana i te rerekētanga nui o ā rātou tohu i ia hāora, ā, ka āwhina te selegiline ki te whakatikatika i ēnei pikinga me te hekenga.

Me pēhea te mahi a te Selegiline?

Ka mahi te Selegiline mā te aukati i te MAO-B, he enzyme e wawahi ana i te dopamine i roto i tō roro. Ki te mate koe i te mate o Parkinson, ka mate haere ngā pūtau roro e whakaputa ana i te dopamine, nō reira ko te tiaki i te dopamine e toe ana ki a koe ka tino nui mō te whakahaere i ngā tohu.

E kiia ana he kaha ngā rongoā nei i roto i ngā rongoā mō te mate o Parkinson. Kāore i te kaha pērā i te levodopa, e kīia ana ko te paerewa koura, engari he nui ake te whāinga, ā, ka taea te whakarato i te whakamaarama tohu whai hua me te iti ake o ngā pānga taha.

Ka roa te pānga tiaki o te selegiline mō ētahi rā i muri i tō tango. Ko te tikanga ka noho tonu te enzyme i te aukati ahakoa kua wehe te rongoā i tō toto, e whakarato ana i ngā painga roa atu i ētahi atu rongoā mō te mate o Parkinson.

Kāore i rite ki ētahi rongoā mō te mate o Parkinson e whakakapi ana i te dopamine ngaro, ka āwhina te selegiline ki te pupuri i te whakaputanga dopamine tūturu o tō tinana. Ka taea e tēnei huarahi te ngawari ake ki tō pūnaha, ā, ka iti ake pea ngā raruraru i te roanga o te wā.

Me pēhea taku tango i te Selegiline?

Tangohia te selegiline i runga i te tohutohu a tō tākuta, te nuinga kotahi, e rua rānei i ia rā me te kai, kāore rānei. Ko te horopeta tīmata noa ko te 5mg e rua i ia rā, ka tangohia me te parakuihi me te tina kia kore ai e raru te moe.

Mēnā kei te tango koe i ngā papa e rewa ana i te waha, waiho ki tō arero ka waiho kia rewa katoa. Kaua e ngaungau, e kuru, e horomia rānei ēnei papa katoa, nā te mea ka pā tēnei ki te pai o te mahi a te rongoā.

He mea nui te wā mō te selegiline nā te mea ka raru pea te moe ki te tangohia i te wā roa rawa atu o te rā. Tangohia tō horopeta whakamutunga i mua i te 2 PM hei ārai i te moe kore, i te noho pōuri rānei i te wā moe.

Ka taea e koe te tango selegiline me te kore kai rānei, engari mā te tango me te paramanawa iti ka āwhina pea ki te whakaiti i te puku. Kaua e tangohia me ngā kai nui e nui ana te tyramine-rich pēnei i te tīhi tawhito, te mīti rāpoi, i ngā hua rewena rānei.

Kaua e mutu ohorere te tango selegiline me te kore e kōrero tuatahi ki tō tākuta. Ka tere pea te kino o ō tohumate Parkinson ki te whakamutua ohorere e koe te rongoā.

Kia Pēhea te Roa o taku Tango Selegiline?

Ko te nuinga o te hunga e mate ana i te mate Parkinson e tango ana i te selegiline mō ngā tau maha hei wāhanga o tā rātou mahere rongoā wā roa. Ko te rongoā te mea pai rawa atu ki te tangohia i ngā wā katoa, e āwhina ana ki te pupuri i ngā taumata dopamine i roto i tō roro.

Ka arotakehia e tō tākuta i ngā wā katoa te pai o te mahi a te selegiline mō koe mā ngā hui whai-whai. Ka arotakehia e rātou mēnā kei te pai te whakahaere i ō tohumate, me mēnā e hiahiatia ana ētahi whakatikatika ki tō mahere rongoā.

Ko ētahi tāngata me tango pea te selegiline mō te toenga o ō rātou oranga, ina koa ki te whakapai ake i te kounga o te oranga me te whakahaere tohumate. He mea noa tēnei, ā, e tūmanakohia ana mō ngā āhuatanga mau tonu pēnei i te mate Parkinson.

Kei te whakawhirinaki hoki te roa o te rongoā ki te ahunga whakamua o tō āhuatanga, me mēnā ka hiahiatia ētahi atu rongoā. Ka tāpirihia pea e tō tākuta ētahi atu rongoā, ka whakatika rānei i tō horopeta selegiline i te huringa o ō hiahia i te wā.

He Aha ngā Pānga Taha o te Selegiline?

Pērā i ngā rongoā katoa, ka taea e te selegiline te pānga taha, ahakoa he maha ngā tāngata e pai ana ki te tango. Ko ngā pānga taha tino noa he ngawari noa iho, ā, he maha ngā wā ka pai ake i te urutau o tō tinana ki te rongoā.

Koinei ngā pānga taha ka pā ki a koe, ka tīmata mai i ngā mea tino noa:

• Te whakapairuaki me te puku puku
• Te whanoke, te mārō rānei
• Te uaua ki te moe, ngā moemoea rānei e mōhiotia ana
• Te waha maroke
• Te Ūpoko
• Te rangirua, ngā whakakitenga rānei
• Te piki ake o ngā nekehanga kore

Ko ēnei pānga taha noa ka ngaro i roto i ngā wiki torutoru i te wā e waia ana tō tinana ki te rongoā. Ki te mau tonu, ki te pōraru rānei, ka taea e tō tākuta te whakatika i tō horopeta, i te wā rānei hei āwhina.

Ko ngā pānga taha nui ake engari he onge, ka uru pea ko ngā huringa nui o te ngākau, te mamae o te uma, te pikinga ohorere rānei o te pēhanga toto. Me whai wāhi tonu tēnei ki te rongoā, ā, he nui ake te tūponotanga ki te puta ki te kai koe i ētahi kai, ki te tango rānei i ētahi atu rongoā e pā ana ki te selegiline.

Ka pā te 'pānga tīhi' ki ētahi tāngata ki te kai rātou i te nui o ngā kai whai tyramine i te wā e tango ana i te selegiline. Ka taea e tēnei te pānga i ngā pikinga kino o te pēhanga toto, ahakoa he mea noa i ngā horopeta e whakamahia ana mō te mate Parkinson.

Ko wai kāore e tika ana kia tango i te Selegiline?

Me karo ētahi tāngata i te selegiline nā te mea ka pā kino ki ētahi atu rongoā, ki ngā āhuatanga hauora rānei. Ka āta arotakehia e tō tākuta tō hītori hauora me ngā rongoā e whakamahia ana i mua i te whakahau.

Kāore koe e tika kia tango i te selegiline ki te whakamahi koe i ētahi rongoā anti-pōuri, ina koa ko ngā SSRI, SNRIs, ngā rongoā anti-pōuri tricyclic rānei. Ka taea e te huinga te pā i tētahi āhuatanga nui e kīia ana ko te syndrome serotonin, e mōrearea ana ki te ora.

Ko ngā tāngata e tango ana i ngā rongoā mamae opioid pēnei i te meperidine, tramadol, methadone rānei me karo hoki i te selegiline. Ka taea e ēnei huinga te pā i ngā urupare nui tae atu ki te kirika nui, te mārō o te uaua, me ngā huringa kino i te pēhanga toto.

Ki te whai mate ate nui koe, ka whiriwhiria e tō tākuta tētahi rongoā rerekē nā te mea ka tukatukahia te selegiline e te ate. Waihoki, ko ngā tāngata whai mate tākihi nui pea me whakatika te horopeta, me whai rānei i ngā rongoā kē.

Me kōrero tonu ki tō tākuta mō ngā rongoā katoa e inu ana koe, tae atu ki ngā rongoā ka taea te hoko, ngā tāpiringa, me ngā rongoā otaota. Ahakoa ngā hua e kore e whara pērā i te St. John's wort ka taea te pā tahi ki te selegiline.

Ngā Ingoa Waitohu o Selegiline

Kei te wātea te Selegiline i raro i ētahi ingoa waitohu, ko Eldepryl te mea e mōhiotia ana. Koinei te ingoa waitohu taketake mō te puka papa o te selegiline e tohutohu ana ngā tākuta mō ngā tau tekau.

Ko Zelapar tētahi atu ingoa waitohu, mō ngā papa e rewa ana i te waha. He māmā ake ēnei papa mō te hunga e uaua ana ki te horo i ngā pire nā te mate o Parkinson.

Kei te wātea whānui ngā puka generic o te selegiline, ā, he rite tonu te whai hua ki ngā puka waitohu. Ka taea e tō kai rongoā te kōrero ki a koe ko tēhea puka e whiwhi ana koe, ā, ka whakautu i ngā pātai mō ngā rerekētanga i waenga i ngā waitohu.

He rite tonu te whakauru kaha ahakoa te ingoa waitohu, nō reira ko te huri i waenga i ngā kaihanga rerekē e kore e pā ki te pai o te rongoā mō koe.

Ngā Kōwhiringa kē o Selegiline

Mēnā kāore te selegiline i te tika mōu, he maha atu ngā rongoā ka taea te āwhina i te whakahaere i ngā tohumate o te mate o Parkinson. Ka whakaaro pea tō tākuta ki te rasagiline, he aukati MAO-B hou e mahi ana i te rite ki te selegiline engari he iti ake pea ngā pānga taha.

Ko ngā kaiwhakawhiwhi dopamine pērā i te pramipexole, i te ropinirole rānei, e mahi rerekē ana mā te whakaihiihi tika i ngā kaiwhiwhi dopamine i tō roro. He whai hua pea ēnei rongoā, ina koa i ngā wāhanga tuatahi o te mate o Parkinson.

Ko ngā aukati COMT pērā i te entacapone, i te tolcapone rānei, tētahi atu kōwhiringa e āwhina ana ki te whakawhānui i ngā pānga o te levodopa. E mahi ana ēnei mā te aukati i tētahi enzyme rerekē e wawahi ana i te levodopa i mua i tōna tae ki tō roro.

Ka whakaaro pea tō tākuta ki te amantadine, he maha ngā huarahi hei āwhina i ngā tohumate o Parkinson, ā, he tino whai hua pea mō te whakaiti i ngā nekehanga kore i puta mai i ētahi atu rongoā.

Ko te kōwhiringa pai rawa atu kei runga i ō tohumate motuhake, ētahi atu rongoā e tango ana koe, me te pēhea te urupare o tō tinana ki ngā momo rongoā rerekē. Ka mahi tō tākuta ki a koe ki te kimi i te huinga tino whai hua.

He Pai Ake A Selegiline I A Rasagiline?

Ko te selegiline me te rasagiline he aukati MAO-B e mahi ana i ngā huarahi rite, engari he rerekētanga nui ō rāua. He rongoā hou a Rasagiline, ā, he iti ake pea ngā pānga taha me ngā pānga rongoā i te selegiline.

Kua roa te whakamahi i te Selegiline, ā, he nui ake ngā rangahau e tautoko ana i tōna whai huatanga, ina koa ka honoa ki te levodopa. Kei te wātea hoki i roto i ngā momo maha, tae atu ki ngā papa e ngaro ana i te waha e māmā ake ana te tango e ētahi tāngata.

Kāore pea a Rasagiline e pā ana ki ngā raruraru moe nā te mea kāore e pakaru ana ki ngā matū rite ki te amphetamine i tō tinana. Mā tēnei ka pai ake mō ngā tāngata e tairongo ana ki ngā pānga whakaihiihi.

Kāore tētahi rongoā i te tino

Mena he mate ngakau tō, tērā pea ka tīmata tō tākuta i tētahi horopeta iti, ā, ka whakanuia haere. Ka hiahia anō rātou ki te kite i a koe i ngā marama tuatahi kia mōhio ai me pēhea te urupare o tō ngākau ki te rongoā.

Kōrero tonu ki tō tākuta mēnā ka pā mai te mamae o te uma, te pōrearea o te manawa, te poto rānei o te manawa i te wā e tango ana koe i te selegiline. Ko ēnei tohumate e tohu ana me mātakitaki tata atu tō āhua ngākau, me whakatika rānei te rongoā.

Q2. Me pēhea taku mahi mēnā ka inu au i te nui rawa o te Selegiline?

Mēnā ka inu koe i te nui rawa o te selegiline, whakapā atu ki tō tākuta, ki te pūtau whakahaere paitini rānei, ahakoa e pai ana tō tū. Kāore pea e puta tonu ngā tohumate o te horopeta nui, engari ka uru pea te mamae nui o te upoko, te mamae o te uma, ngā huringa rānei o te pēhanga toto e mōrearea ana.

Kaua e ngana ki te whakapōka, ki te tango rānei i ētahi atu rongoā hei whakakore i te horopeta nui. Engari, kohikohia tō pounamu rongoā, ka haere ki te ruma ohorere tata mēnā ka tūtohu tō tākuta.

Puritia he rārangi o au rongoā katoa ki a koe, tae atu ki te horopeta tika o te selegiline i inumia e koe. Mā ēnei kōrero e āwhina ngā tāngata rongoā ki te whakarato i te manaakitanga pai rawa atu mēnā e hiahia ana koe ki te rongoā ohorere.

Q3. Me pēhea taku mahi mēnā ka ngaro i ahau tētahi horopeta o te Selegiline?

Mēnā ka ngaro i a koe tētahi horopeta o te selegiline, tangohia i te wā e mahara ana koe, ki te kore i te ahiahi rānei. Ko te tango i te selegiline i te wā roa rawa i te rā ka raru pea i tō moe.

Mēnā kua pahure kē i te 2 PM i te wā e mahara ana koe ki tō horopeta i ngaro, waiho, ka tango i tō horopeta e whai ake nei i te wā tika. Kaua e rua ngā horopeta hei utu mō te mea i ngaro, nā te mea ka piki ake tō tūponotanga ki ngā pānga taha.

Kāore e whara i a koe te ngaro i tētahi horopeta i ētahi wā, engari ngana ki te pupuri i tētahi wāhanga rite tonu kia pai ai te whakahaere i ngā tohumate. Whakaarohia te whakatakoto i ngā whakamārama waea, te whakamahi rānei i tētahi kaiwhakarite pire hei āwhina i a koe ki te mahara.

Q4. Āhea au e mutu ai te tango i te Selegiline?

Kaua e whakamutua te tango selegiline ohorere me te kore e kōrero tuatahi ki tō tākuta. Ka kaha ake pea ō tohu Parkinson i te wa e whakamutua ohoreretia ana te rongoā, ā, ka pā pea ō pānga rite ki te tangohanga.

Ka āwhina tō tākuta i a koe ki te whakaiti i tō horopeta i roto i ngā wiki maha ki te tika te whakamutu i te selegiline. Mā tēnei tukanga whakaiti haere e ārai te hokinga ohorere mai o ngā tohu me te tuku i tō tinana ki te whakatika.

Ko te whakatau ki te whakamutu i te selegiline ka puta i te nuinga o te wā ka nui rawa ngā pānga taha, i te wā rānei ka pai ake ētahi atu rongoā mō tō āhua. Ka mahi tō tākuta ki a koe ki te kimi i te rongoā pai rawa atu i mua i te whakamutu i te selegiline.

Q5. Ka taea e au te inu waipiro i te wā e tango ana au i te Selegiline?

He pai ki te whakaiti i te inu waipiro i te wā e tango ana i te selegiline, nā te mea ka kaha ake te waipiro i ētahi pānga taha pēnei i te whanoke me te rangirua. He pai te iti o te waipiro, engari karohia te inu nui, te inu rānei i te nui.

Kia tūpato ki te waina whero me te pia, nā te mea kei roto i ēnei te tyramine, ka taea te pānga ki te selegiline ki te whakapiki i te pēhanga toto. Ko ngā wairua mārama pēnei i te vodka, te gin rānei te nuinga o te wā he pai ake te kōwhiri mēnā ka whiriwhiri koe ki te inu.

Kōrero ki tō tākuta mō ō tikanga inu waipiro kia taea e rātou te tuku tohutohu whaiaro ki a koe. Ka tūtohu pea rātou kia karohia te waipiro katoa mēnā kei te pā ō pānga taha, kei te tango rānei koe i ētahi atu rongoā e pā ana ki te waipiro.