He aha te Tapinarof: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu mea
Created at:1/13/2025
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He rongoā ā-roto hou te Tapinarof e āwhina ana ki te rongoā i te psoriasis pātea mā te mahi rerekē atu i ngā rongoā tuku iho. He kirīmi tēnei e whakamahia ana e koe ki ngā wāhi kiri e pā ana, ā, nō te kāwai rongoā e kīia nei ko te aryl hydrocarbon receptor agonists. E whai wāhi ana tēnei rongoā mō te hunga e hiahia ana ki tētahi atu momo rongoā i ngā kirīmi steroid, kāore rānei i angitu i ētahi atu rongoā psoriasis.
He aha te Tapinarof?
He kirīmi ā-roto kore-steroidal te Tapinarof i hangaia hei rongoā i te psoriasis pātea i roto i ngā pakeke. Kāore i rite ki ngā kirīmi steroid ka angiangi ai tō kiri i te roanga o te wā, ka mahi rerekē te tapinarof mā tētahi tikanga rerekē kāore e mau ana i ngā tūponotanga roa.
I whakaaetia te rongoā e te FDA i te tau 2022, e waihanga ana i tētahi o ngā kōwhiringa hou e wātea ana mō te rongoā psoriasis. I ahu mai i tētahi pūhui tūturu i kitea i roto i te huakita, engari ko te putanga e whakamahia ana i roto i te rongoā ka hangaia i roto i ngā taiwhanga hei whakarite i te mā me te whai hua.
Ka kitea e koe te tapinarof e wātea ana hei kirīmi 1% e tae mai ana i roto i ngā ngongo o ngā rahi rerekē. He ahua maeneene, mā te kirīmi, ā, ka horahia ngāwari ki tō kiri me te kore e waiho i te toenga hinu.
He aha te Tapinarof e whakamahia ana mō?
Ko te Tapinarof te mea nui e whakamahia ana hei rongoā i te psoriasis pātea, koinei te momo psoriasis e pā ana ki te miriona o te tangata puta noa i te ao. Ka waihanga te psoriasis pātea i ngā pāti whero kua piki ake, kua hipokina ki ngā unahi hiriwa ka puta ki hea i runga i tō tinana.
He pai te mahi a te rongoā mō te psoriasis pātea ngawari ki te āhua. Ka tūtohu pea tō tākuta i te tapinarof mēnā he pāti psoriasis tō i ngā wāhi pēnei i ō tūātae, ō pūhiwi, ō mahunga, ētahi atu wāhi tinana kāore i pai te urupare ki ētahi atu rongoā.
E tohutohu ana etahi tākuta i te tapinarof mō ngā tūroro e hiahia ana ki te karo i te whakamahi steroid mō te wā roa. I te mea kāore he steroid, ka taea e koe te whakamahi mō te wā roa, kāore he āwangawanga mō te kikokore o te kiri, ētahi atu pānga taha rānei e pā ana ki te steroid.
Me pēhea te mahi a Tapinarof?
Ka mahi a Tapinarof mā te whakahohe i tētahi mea e kīia ana ko te aryl hydrocarbon receptor i roto i ō pūtau kiri. Ko tēnei receptor e mahi ana pērā i te huri e āwhina ana ki te whakahaere i te mumura me te whakatairanga i te tipu noa o ngā pūtau kiri.
Ka pā mai te psoriasis, ka tere rawa te whakaputa o ō pūtau kiri, ka hanga i ngā pāti matotoru, he unahi. Ka āwhina a Tapinarof ki te whakaiti i tēnei tipu tere o ngā pūtau i te wā e whakaiti ana i te mumura e pā ana ki te whero me te riri.
E whakaarohia ana he kaha ngāwari te rongoā, engari he ngawari ake i te maha o ngā rongoā psoriasis i runga i te tohutohu. E hia wiki te roa ki te whakaatu i ōna pānga katoa, nō reira he mea nui te manawanui i te tīmatanga o tēnei rongoā.
Me pēhea taku tango i te Tapinarof?
Whakamahia te kirīmi tapinarof kotahi i te rā ki ngā wāhi e pā ana ki tō kiri, he pai ake i te wā kotahi i ia rā. Kāore koe e hiahia ki te tango me te kai, te wai rānei i te mea ka whakamahia tika ki tō kiri.
Anei me pēhea te whakamahi tika i te tapinarof:
- Horoi tino pai ō ringa i mua i te whakamahi i te kirīmi
- Horoi marie i te wāhi kiri e pā ana, ka maroke
- Whakamahia tētahi paparanga angiangi o te kirīmi hei uhi katoa i ngā pāti psoriasis
- Miria marie te kirīmi kia ngaro rawa atu ki tō kiri
- Horoi anō ō ringa i muri i te whakamahi, ki te kore koe e rongoā i ō ringa
Ka taea e koe te whakamahi tapinarof ki te 20% o tō rohe mata o te tinana. Kaua e whakamahi i te nui ake o te kirīmi i te mea e tohutohutia ana, i te mea kāore tēnei e mahi tere ake, ā, ka piki ake pea tō tūponotanga ki ngā pānga taha.
Ka pai te mahi o te kirīmi ina whakamahia ki te kiri mā, maroke. Kāore koe e hiahia ki te karo i te kai i ētahi kai, ki te tango rānei i ētahi whakatūpato motuhake me ngā kai i te mea ka whakamahia te tapinarof ki te wāhi.
Kia pehea te roa e tango ai au i te Tapinarof?
He maha ngā tāngata e whakamahi ana i te tapinarof mō ētahi marama kia kite i te whakapainga nui i ngā tohumate o te psoriasis. I whakaatu ngā rangahau haumanu he maha ngā tūroro i kite i ngā painga e kitea ana i muri i te 12 wiki o te whakamahi i ia rā.
Ka tohutohu pea tō tākuta ki a koe kia whakamahi i te tapinarof mō te 3 ki te 6 marama kia whai wā ai ki te mahi pai. Ko ētahi tāngata ka hiahia pea ki te whakamahi mō te wā roa ake, i runga i te urupare o tō rātou kiri ki te rongoā.
Kāore i rite ki ngā kirīmi steroid e hiahia ana ki ngā okiokinga hei ārai i ngā pānga taha, ka taea te whakamahi tonu i te tapinarof mō ngā wā roa. Ka aroturuki tō tākuta i tō ahunga whakamua, ā, ka whakatika pea i tō mahere rongoā i runga i te pai o te whakapai o tō kiri.
He aha ngā Pānga Taha o te Tapinarof?
He pai te aro o te nuinga o te tāngata ki te tapinarof, engari pērā i ētahi rongoā, ka pānga taha pea. Ko te rongo pai he mea noa ngā pānga taha nui ki tēnei rongoā ā-rohe.
Ko ngā pānga taha tino noa ka pā ki a koe ko:
- Te riri kiri, te whero rānei i te wāhi tono
- Te mōmō, te wera rānei i te wā tuatahi ka tono
- Te kiri maroke i ngā wāhi i rongoatia
- Te wero ngawari e pai ake ana i te wā
- Folliculitis (ngā pūpū iti huri noa i ngā makawe)
Ko ēnei pānga taha he ngawari te nuinga, ā, ka pai ake i te wā e waia ana tō kiri ki te rongoā. Ko te nuinga o te tāngata e kite ana ka heke te riri tuatahi i muri i ngā wiki tuatahi o te whakamahi.
Ko ngā pānga taha onge engari nui ake ka uru ki ngā tauhohenga mate pāwera nui. Ki te pā ki a koe te rāwaho whānui, te uaua ki te hā, te pūhi rānei o tō mata, ngā ngutu, te korokoro rānei, me rapu tonu i te āwhina hauora.
Ka whakawhanake pea ētahi tāngata i te dermatitis whakapā, e pā ana ki te riri kiri nui atu i te tikanga. He mea noa tēnei engari me whakamutu te rongoā me te kōrero ki tō tākuta mō ētahi atu rongoā.
Ko wai kāore e tika kia tango Tapinarof?
Kāore a Tapinarof e tika ana mō te katoa, engari ka taea e te nuinga o ngā pakeke e pangia ana e te psoriasis pātea te whakamahi i te haumaru. Me karo koe i tēnei rongoā mēnā he pānga tō ki a tapinarof, ki ētahi atu whakauru rānei o te kirīmi.
Kāore ngā tamariki kei raro i te 18 tau te pakeke e whakamahi i te tapinarof mai i te mea kāore anō ngā rangahau i whakatū i tōna haumaru me tōna whai huatanga i roto i ngā tūroro tamariki. Me kōrero ngā wāhine hapū i ngā tūponotanga me ngā painga ki tō rātou tākuta i mua i te whakamahi i tēnei rongoā.
Ko ngā tāngata e pangia ana e ētahi āhuatanga kiri e whakanui ana i tō rātou tairongo ki ngā rongoā ā-rohe, tērā pea me karo i te tapinarof. Ka taea e tō tākuta te āwhina i te whakatau mēnā he tika tēnei rongoā mō tō āhuatanga motuhake.
Ngā Ingoa Waitohu o Tapinarof
E hokona ana a Tapinarof i raro i te ingoa waitohu Vtama i te United States. Koinei anake te ingoa waitohu e wātea ana mō tēnei rongoā, i te mea he hou tonu ki te mākete.
Kei roto i a Vtama te 1% tapinarof hei whakauru kaha. E wātea ana te kirīmi i roto i ngā ngongo 30-karamu me te 60-karamu, i runga i te nui o te wāhi kiri e hiahia ana koe ki te rongoā.
Kāore anō ngā putanga whānui o te tapinarof i te wātea mai i te mea kei te tiakina tonu te rongoā e te pātēneti. Ko te tikanga ko Vtama anake tō kōwhiringa mō te whiwhi rongoā tapinarof i tēnei wā.
Ngā Kōwhiringa kē mō Tapinarof
He maha atu ngā rongoā ā-rohe ka taea te rongoā i te psoriasis pātea mēnā kāore a tapinarof e mahi mō koe, kāore rānei e tika ana. E mahi ana ēnei kōwhiringa kē mā ngā momo tikanga rerekē, ā, tērā pea he kōwhiringa pai ake i runga i ō hiahia motuhake.
Ko ngā corticosteroids ā-rohe tonu te rongoā psoriasis e tino whakahauhia ana. Kei roto i ēnei ngā rongoā pēnei i te clobetasol, betamethasone, me te triamcinolone, e whakaiti ana i te mumura i te tere, engari me mātakitaki i te whakamahi wā-roa.
Ko ngā tairitenga Vitamin D pēnei i te calcipotriene (Dovonex) e tuku ana i tētahi atu kōwhiringa kore-steroid. E āwhina ana ēnei rongoā i te whakatau i te tipu o ngā pūtau kiri, ā, ka taea te whakamahi wā-roa me te kore ngā tūponotanga e pā ana ki ngā steroids.
Kei roto i ngā kōwhiringa hou ko te roflumilast (Zoryve), tētahi rongoā ā-rohe kāore i te steroid e mahi ana mā te aukati i tētahi enzyme e kīia ana ko PDE4. I whakaaetia tēnei rongoā i te wā kotahi me te tapinarof, ā, he rite tonu ngā painga.
He Pai Anei te Tapinarof i te Clobetasol?
He rerekē te mahi a te tapinarof me te clobetasol, ā, he rerekē ngā painga i runga i tō āhuatanga. He steroid ā-rohe tino kaha te clobetasol e mahi ana i te tere, engari he nui ake ngā tūponotanga i te wā roa.
Ko te tikanga, ka kitea ngā hua o te clobetasol i roto i ngā rā ki ngā wiki, engari ka roa pea te tapinarof i ngā wiki ki ngā marama kia tino whai hua. Heoi anō, ka taea e te clobetasol te whakaheke i te kiri, te tohu totoro, me ētahi atu pānga taha i te wā roa e whakamahia ana.
E whai ana te tapinarof i te painga o te noho haumaru mō te whakamahi i te wā roa, kāore he āwangawanga e pā ana ki ngā steroid kaha. He maha ngā wā ka whakaarohia he pai ake mō te rongoā tiaki i te wā e whakahaerehia ana tō psoriasis.
Ka tūtohu pea tō tākuta kia tīmata ki te clobetasol mō te āwhina tere, katahi ka huri ki te tapinarof mō te whakahaere i te wā roa. E whakakotahi ana tēnei huarahi i te mahi tere o ngā steroid me te pūkete haumaru o te tapinarof.
Ngā Pātai e Pātai Pinepine ana mō te Tapinarof
He Haumaru te Tapinarof mō te Mate Huka?
Āe, he haumaru te tapinarof mō ngā tāngata e mate huka ana, i te mea e whakamahia ana ā-rohe, ā, kāore e pā ana ki ngā taumata huka toto. E mahi ana te rongoā i te rohe i runga i tō kiri, ā, kāore e pokanoa ki ngā rongoā mate huka, ki te insulin rānei.
Heoi anō, me mātakitaki ngā tāngata e mate huka ana i tō rātou kiri i te wā e whakamahi ana i tētahi rongoā ā-rohe hou. Ka taea e te mate huka te whakaroa i te whakaora i ngā patunga me te whakanui i te tūponotanga o te mate, nō reira me pūrongo ngā huringa kiri rerekē ki tō tākuta.
Me Pēhea Taku Mahi Mēnā Ka Whakamahi Au i te Nui Rawa o te Tapinarof?
Kāore i te mōrearea te whakamahi i te nui rawa o te tapinarof i ētahi wā, engari kāore e pai ake ai te mahi o te rongoā. Me horoi noa i te kirīmi nui, ā, me haere tonu ki tō tikanga whakamahi noa i te rā e whai ake nei.
Mēnā e whakamahi tonu ana koe i te kirīmi nui rawa atu, tērā pea ka nui ake te riri o tō kiri i te tikanga. Whakaitihia te nui e whakamahia ana e koe, ā, me whakamahi anake i tētahi paparanga angiangi e hipoki katoa ana i ngā wāhi e pā ana.
Me Pēhea Taku Mahi Mēnā Kua Ngaro Taku Inenga o Tapinarof?
Mēnā kua wareware koe ki te whakamahi i te tapinarof, whakamahia i te wā e mahara ana koe i te rā kotahi. Kaua e whakamahi i te kirīmi atu i te rā e whai ake nei hei utu mō te inenga i ngaro.
Kāore he kino ki a koe mēnā ka ngaro ētahi inenga, engari ko te whakamahi i ia rā ka whai hua pai ki a koe. Whakaarohia te whakatakoto i tētahi whakamaharatanga i ia rā i runga i tō waea hei āwhina i a koe ki te mahara ki te wā e whakamahi ai koe.
Āhea Āhei Ai Au ki te Kati te Tango i te Tapinarof?
Ka taea e koe te whakamutu i te whakamahi i te tapinarof i te wā e whakatau ana tō tākuta kua pai te whakahaere i tō psoriasis, mēnā rānei ka pā ki a koe ngā pānga taha e nui ake ana i ngā painga. Kaua e mutu ohorere me te kore e kōrero tuatahi ki tō kaiwhakarato hauora.
Tērā pea ka hiahia ētahi tāngata ki te whakamahi i te tapinarof mō te wā roa kia mau tonu te kiri mā, i te wā e huri ana ētahi ki tētahi atu rongoā tiaki. Mā tō tākuta koe e āwhina ki te whakawhanake i te rautaki pai rawa atu mō te whakahaere i tō psoriasis.
Ka Taea e Au te Whakamahi i te Tapinarof me Ētahi Atu Rongoā Psoriasis?
He maha ngā wā ka taea te whakakotahi i te tapinarof me ētahi atu rongoā psoriasis, engari me tirotiro tonu koe ki tō tākuta i te tuatahi. He pai te mahi tahi o ētahi whakakotahitanga, i te wā e piki ake ai te tūponotanga o te riri o tō kiri i ētahi atu.
Tērā pea ka tūtohu tō tākuta ki te whakamahi i te tapinarof me ngā whakamākū, ngā horoi ngawari, ētahi atu rongoā rānei e whakamahia ana ki te kiri. Mā rātou koe e āwhina ki te waihanga i tētahi mahere rongoā whānui e whakanui ana i ngā painga i te wā e whakaiti ana i ngā pānga taha.