He aha te Ubrogepant: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

Ko te Ubrogepant he rongoā i runga i te whakahaunga i hangaia hei rongoā i ngā mamae mōmona i te wā e tīmata ana. No roto i tētahi rōpū rongoā mōmona hou e kīia ana ko CGRP receptor antagonists, e mahi ana mā te aukati i ngā tohu mamae motuhake i tō roro i te wā o te whakaeke mōmona.

E whai wāhi ana tēnei rongoā mō te hunga kāore i kite i te whakamaungia i ngā rongoā mōmona tuku iho. Kāore i rite ki ētahi rongoā mōmona tawhito, kāore te ubrogepant e pā mai i ngā mamae mōmona rebound, ā, ka taea te whakamahi pinepine ake i te wā e hiahiatia ana.

He aha te Ubrogepant e whakamahia ana mō?

Ka rongoā te Ubrogepant i ngā whakaeke mōmona koi i roto i ngā pakeke, te tikanga ka tangohia i te wā e whai mamae mōmona ana koe. E mahi ana te rongoā ki te aukati i te mamae mōmona me ngā tohu e pā ana pēnei i te whakapairuaki, te tairongo ki te mārama, me te tairongo ki te oro.

Ka tohua pea e tō tākuta te ubrogepant mēnā ka pā mai i a koe ngā mōmona āhua ki te kaha e raru ana i ō mahi o ia rā. He tino āwhina mō te hunga kāore e taea te tango triptans (tētahi atu rōpū rongoā mōmona) nā te mate ngākau, ētahi atu raruraru hauora rānei.

Kāore tēnei rongoā e whakamahia ana hei aukati i ngā mōmona kia puta. Engari, ko te mea e kīia ana e ngā tākuta he rongoā "abortive" e tangohia ana e koe i te tohu tuatahi o te mōmona hei āwhina i te aukati i te ara.

Me pēhea te mahi a te Ubrogepant?

Ka aukati te Ubrogepant i ngā kaiwhiwhi CGRP i tō roro, e whai wāhi ana ki ngā tohu mamae mōmona. Ko te CGRP e tū ana mō te calcitonin gene-related peptide, he pūmua e kaha rawa ana i te wā o ngā whakaeke mōmona me te whai wāhi ki te mamae kaha me ētahi atu tohu.

Whakaarohia te CGRP hei kī e iriti ana i ngā ara mamae i tō roro i te wā o te mōmona. E mahi ana te Ubrogepant pēnei i te uhi whakamarumaru i runga i te raka, e aukati ana i te CGRP mai i te whakaoho i aua tohu mamae.

He rongoā kaha tēnei e whakaarohia ana mō te rongoā i te migraine. He kaha ake te whai i ngā whāinga i ngā rongoā mamae tawhito, engari kāore pea i te kaha tonu pērā i ētahi rongoā werohanga. Heoi anō, ko tōna mahi motuhake te tikanga he iti ake ngā pānga taha mō te nuinga o te tāngata.

Me pēhea taku tango i te Ubrogepant?

Tangohia te ubrogepant kia rite ki tā tō tākuta i whakahau ai, te tikanga he papa kotahi 50mg, 100mg rānei i te wā e pōro ana koe i te tīmatanga o te migraine. Ka taea e koe te tango me te kore kai rānei, ahakoa e kite ana ētahi tāngata he māmā ake ki tō rātou puku i te wā e tango ana me te paramanawa māmā.

Horomia te papa katoa me te wai. Kaua e kuru, e whati, e ngaungau rānei, nā te mea ka pā tēnei ki te mahi o te rongoā i tō tinana.

Anei ngā mea me mōhio koe mō te wā me te kai i mua i te tango i te ubrogeant:

• Tangohia i te wā tonu ka kite koe i ngā tohumate migraine e tīmata ana
• Ka taea e koe te kai noa i mua i te tango, ahakoa ko ngā kai taumaha, ngako pea ka whakaroa i ōna pānga
• Mēnā ka hoki mai tō migraine i muri i te whakamaungia tuatahi, ka taea e koe te tango i te horopeta tuarua i muri i te 2 hāora
• Kaua e tango i te nui atu i te 200mg i roto i te wā 24-hāora

Ko te wawe ake ka tango koe i te ubrogepant i muri i te tīmatanga o tō migraine, ka pai ake te mahi. He maha ngā tāngata e kite ana i te tino whai hua i te wā e tango ana i te hāora tuatahi o ngā tohumate.

Kia Pēhea te Roa e Tango Ana ahau i te Ubrogepant?

Ka tangohia te Ubrogepant i te wā e pā ana koe ki te migraine, kāore i te rongoā o ia rā. I ia wā e whakamahi ana koe, kei te rongoā koe i tētahi wāhanga migraine motuhake.

Ka whakatau tō tākuta i te auau ka taea e koe te whakamahi i te ubrogepant i runga i tō auau migraine me ētahi atu āhuatanga hauora. Ka taea e te nuinga o te tāngata te whakamahi i te 8 ngā wā i te marama, engari he rerekē tēnei i runga i tō āhuatanga takitahi.

Mēnā ka kite koe e hiahia ana koe ki te ubrogepant i te auau, ka tūtohu pea tō tākuta ki te tāpiri i te rongoā migraine aukati hei whakaiti i te auau ka pā koe ki te migraine i te tuatahi.

He aha ngā Pānga Taha o te Ubrogepant?

He pai te manawanui o te nuinga o te tangata ki te ubrogepant, engari pērā i ngā rongoā katoa, ka pā ngā pānga taha. Mā te māramatanga ki ngā mea e tūmanakohia ana ka āwhina koe ki te whai māia ki tō rongoā.

Ko ngā pānga taha e tino kitea ana he ngawari, he wā poto:

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• Te whakapairuaki (e pā ana ki te 4% o te tangata)
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• Te hōhā, te ngenge rānei
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• Te waha maroke
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• Te whanoke
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• Te mamae o te puku
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Ko ēnei pānga taha e kitea ana ka ngaro i roto i ngā hāora ruarua, ā, kāore e hiahiatia kia whakamutua te rongoā. Heoi, ki te mau tonu, ki te kino rānei, whakamōhio atu ki tō tākuta.

Ka puta ngā pānga taha kāore i te kitea, engari he nui ake te kino, ahakoa he onge. Kei roto i ēnei ko ngā tauhohenga mate pāwera nui me ngā tohu pērā i te uaua ki te hā, te pūhi o tō mata, o tō korokoro rānei, te pāngia kiri nui rānei.

Ka pā ki ētahi tāngata te mea e kīia ana ko te

E hokona ana te Ubrogepant i raro i te ingoa waitohu Ubrelvy. Koinei anake te ingoa waitohu e wātea ana i tēnei wā mō tēnei rongoā i te United States.

Ka tae mai a Ubrelvy hei papa waha i roto i ngā kaha e rua: 50mg me te 100mg. Māu tō tākuta e whakatau ko tēhea te kaha e pai ana mō tō tauira migraine me tō kaha.

I tēnei wā, kāore he momo generic o te ubrogepant e wātea ana, ko te tikanga he nui ake te utu o Ubrelvy i ngā rongoā migraine tawhito. Heoi, he maha ngā mahere inihua e hipoki ana, ā, e tuku ana te kaihanga i ngā hōtaka āwhina tūroro mō te hunga e tika ana.

Ngā Kōwhiringa kē mō te Ubrogepant

Mēnā kāore te ubrogepant e pai ana mōu, e pā rānei i ngā pānga taha e whakararuraru ana, he maha atu ngā kōwhiringa maimoatanga migraine e wātea ana. Ka taea e tō tākuta te āwhina i a koe ki te kimi i te kōwhiringa pai rawa atu i runga i ō hiahia motuhake.

Ko ētahi atu kaiwhakatūtū CGRP receptor ko te rimegepant (Nurtec ODT), e rewa ana i tō arero, me te zavegepant (Zavzpret), e tae mai ana hei rehu ihu. He rite te mahi ki te ubrogepant engari he pai ake pea mōu mēnā he uaua ki a koe te horo i ngā pire.

Ngā rongoā migraine tuku iho ka mahi pea hei kōwhiringa kē ko:

• Ngā triptans pēnei i te sumatriptan, i te rizatriptan rānei
• Ngā NSAIDs pēnei i te ibuprofen, i te naproxen rānei
• Ngā rongoā whakakotahi me te caffeine
• Ngā rongoā anti-nausea mō te nausea e pā ana ki te migraine

Ka whai hua hoki ētahi tāngata mai i ngā huarahi kore rongoā pēnei i te whakamahi i te makariri, i te wera rānei, te noho i roto i tētahi ruma pouri, marie rānei, te whakamahi rānei i ngā tikanga whakangā i te taha o ā rātou rongoā.

He Pai Ake te Ubrogepant i te Sumatriptan?

He rerekē te mahi a te Ubrogepant me te sumatriptan, ā, he painga motuhake tō ia. Ko te Sumatriptan, he rongoā triptan, kua roa te whakamahi, ā, he tere te mahi mō ngā migraine kaha, engari he haumaru ake pea te ubrogepant mō te hunga e whai mate ngākau ana.

Ko te painga nui o te ubrogepant ko te kore e whaiti i nga oko toto pera i te triptans. Na tenei ka noho haumaru ake mo nga tangata e mate ana i te ngakau, te toto tiketike, nga mea morearea ranei mo te whiu kaore e taea te tango triptans.

He maha nga wa ka tere ake te awhina a Sumatriptan, i etahi wa i roto i te 30 meneti, ko te ubrogepant te tikanga ka 1-2 haora kia tino whai hua. Heoi, tera pea ka iti ake nga paanga o te taha o te ubrogepant penei i te puku o te uma, te mangere ranei e pa ana ki etahi tangata e triptans ana.

Ka whakaarohia e to taakuta to hauora ngakau, te kaha o te migraine, me te tere o to hiahia ki te awhina i te wa e whiriwhiri ana i waenga i enei rongoa. E kitea ana e etahi tangata he pai ake tetahi i tetahi, a tera pea ka whakamatau kia kitea to whiringa pai.

Nga Pātai e Pātai pinepine ana mo Ubrogepant

He Haumaru te Ubrogepant mo te Toto tiketike?

Ae, ko te ubrogepant te nuinga he haumaru mo nga tangata e mate ana i te toto tiketike. Kaore i rite ki nga rongoa triptan, kaore te ubrogepant e whaiti i nga oko toto, na reira he whiringa pai mo nga tangata e pa ana ki nga raruraru ngakau.

Heoi, me korero tonu koe ki to taakuta mo to mate toto me nga rongoa e tango ana koe mo taua mea. Ka taea e etahi rongoa toto te taunekeneke ki te ubrogepant, a tera pea ka hiahia to taakuta ki te whakatika i te inenga, ki te aro turuki ranei i a koe.

Me aha ahau ki te whakamahi pohehe ahau i te nui rawa o te Ubrogepant?

Mena ka inu pohehe koe i te nui atu i te horopeta e taunakitia ana o te ubrogepant, whakapā atu ki to taakuta, ki te pokapū whakahaere paihana ranei i te wa tonu. Kaua e tatari kia puta nga tohu, na te mea he haumaru ake te tiki tohutohu wawe.

Ko te tango i te nui rawa o te ubrogepant ka nui ake to tupono ki nga paanga o te taha penei i te nausea nui, te mangere, te ngenge ranei. I nga wa onge, ka raru pea te nui o te rongoa, ahakoa te nuinga o te wa ka pai te aro ki tenei rongoa ahakoa i nga horopeta teitei ake.

Kia mau ki te rā ka tango koe i ō horopeta kia kore ai e rua ngā horopeta i te wā kotahi. Ki te kore koe e mōhio kua tango kē koe i tō rongoā, he pai ake te tatari kia kite mena ka pai ake tō migraine i te tūpono ki te tango i te nui rawa.

Me Pēhea Taku Mahi Mēnā Kua Ngaro i Ahau tētahi Horopeta o Ubrogepant?

I te mea ka tangohia te ubrogepant i te wā e pā ana koe ki te migraine, kāore he "horopeta ngaro" i te tikanga tuku iho. Ka tango koe i te wā e hiahia ana koe mō te whakaeke migraine.

Mēnā i wareware koe ki te tango i te ubrogepant i te wā i tīmata ai tō migraine, ā, kua maha ngā hāora i muri mai, ka taea tonu e koe te tango. Ka taea e te rongoā te whai wāhi ki te whakamāmā, ahakoa te nuinga o te wā ka pai ake te mahi i te wā e tango wawe ana i te wāhanga migraine.

Kaua e tango i te rongoā atu hei "whakatika" mō te kore e tango wawe. Kia piri ki ngā aratohu horopeta me te wā i whakaritea e tō tākuta.

Āhea Āhau e Kati ai te Tango i te Ubrogepant?

Ka taea e koe te kati te tango i te ubrogepant i ngā wā katoa i te mea ehara i te rongoā o ia rā e whakawhirinaki ai tō tinana. Ka mutu noa te whakamahi i te wā e kore ai koe e hiahia ana mō te rongoā migraine.

Heoi, i mua i te whakamutu, kōrero ki tō tākuta mō te pai o te mahi a te ubrogepant mō ō migraine. Ki te āwhina ana, kāore he take rongoā hei whakamutu mena kāore koe e pā ana ki ngā pānga taha raruraru.

Mēnā ka iti ake te auau, te kaha rānei o ō migraine, ka whakamahi noa koe i te ubrogepant i ngā wā iti ake. Ka taea e tō tākuta te āwhina i a koe ki te whakatau mēnā e hiahia ana koe ki ngā rongoā kē, ki te whakamahi rānei i te ubrogepant i ngā wā kotahi tonu te huarahi pai.

Ka Taea e Āhau te Tango i te Ubrogepant me Ētahi Atu Rongoā Mamae?

I te nuinga o te wā ka taea e koe te tango i te ubrogepant me ngā rongoā mamae noa i te tākuta, pēnei i te acetaminophen, te ibuprofen rānei, engari me kōrero tonu ki tō tākuta i te tuatahi. E kite ana ētahi tāngata ko te whakakotahi i ngā rongoā ka pai ake te whakamāmā migraine.

Heoi anō, karawhiua te tango ubrogepant me ētahi atu rongoā migraine i runga i te rēhita pēnei i te triptans ki te kore e tohutohutia e tō tākuta. Ko te whakakotahi i ngā rongoā migraine rerekē i ētahi wā ka piki ake ngā pānga taha, ka whakaiti rānei i te whai huatanga.

Kia tūpato rawa ki te tango ubrogepant me ngā rongoā e pā ana ki tō ate, nā te mea me tukatuka rāua e ngā enzyme ate kotahi. Ka taea e tō tākuta te arotake i ō rongoā katoa kia mōhio ai he huinga haumaru.