He aha te kano ārai mate Zoster (Shingrix): Ngā Whakamahinga, te Inenga, Ngā Pānga taha me ētahi atu mea

Ko te kano ārai mate zoster, e mōhiotia ana ko Shingrix, he kano ārai mate whai hua nui e tiaki ana i a koe i te shingles me ōna raruraru. E whakamahi ana tēnei kano ārai mate recombinant i tētahi wāhanga iti o te huaketo varicella-zoster i honoa ki tētahi adjuvant hei whakanui i tō urupare ārai mate, hei āwhina i tō tinana ki te mōhio me te whawhai i te huaketo e pā ana ki te shingles.

Mēnā kei runga ake koe i te 50 tau, he rānei ō tikanga hauora e ngoikore ana i tō pūnaha ārai mate, ka taea e tēnei kano ārai mate te whakaiti i tō tūponotanga ki te whakawhanake i te shingles i te neke atu i te 90%. E kiia ana ko tētahi o ngā kano ārai mate whai hua rawa atu i tēnei rā mō te ārai i tēnei āhuatanga mamae.

He aha te Kano Ārai Mate Zoster (Shingrix)?

Ko Shingrix he kano ārai mate recombinant, adjuvanted i hangaia hei ārai i te shingles (herpes zoster) me ōna raruraru. Kāore i rite ki ngā kano ārai mate ora, kei roto i tēnei kano ārai mate tētahi pūmua iti noa iho mai i te huaketo varicella-zoster, ehara i te huaketo ora tonu.

Kei roto i te kano ārai mate tētahi adjuvant e kiia ana ko AS01B, e mahi ana hei āwhina e kaha ake ai tō pūnaha ārai mate ki te urupare ki te kano ārai mate. E hanga ana tēnei huinga i tētahi urupare ārai mate kaha e taea ai te tiaki i a koe mō ngā tau maha, ahakoa ka ngoikore tō pūnaha ārai mate i te wā.

Ka tukuna te kano ārai mate hei werohanga ki roto i tō uaua o runga ringa, me te hiahia kia rua ngā inenga e 2-6 marama te wā i waenga i ngā inenga mō te tiaki katoa.

He aha te Kano Ārai Mate Zoster e whakamahia ana mō?

Ko te kaupapa tuatahi o Shingrix ko te ārai i te shingles, tētahi āhuatanga kiri mamae e whakawhanake ana i te wā e whakahohe anō ana te huaketo heihei i tō tinana. E tūtohu ana te kano ārai mate mō ngā pakeke 50 tau, neke atu rānei, ahakoa e mahara ana rātou i pā ki te heihei.

I tua atu i te ārai i te shingles, ka tiakina hoki e te kano ārai mate ki te postherpetic neuralgia (PHN), he raruraru nui e mau tonu ana te mamae o te io i muri i te ngaro o te pānga shingles. Ka roa pea tenei āhua mamae mau tonu i ngā marama, i ngā tau rānei, e pā ana ki tō kounga o te oranga.

E taunakitia ana te kano ārai mate mō ngā pakeke 19 tau, neke atu rānei, he ngoikore te pūnaha ārai mate i ngā āhuatanga pēnei i te HIV, te rongoā mate pukupuku, te whakawhitinga okana rānei. Ahakoa kua pā i a koe te shingles i mua, ka āwhina te kano ārai mate ki te ārai i ngā wāhanga kei te heke mai.

Me pēhea te mahi a te kano ārai mate Zoster?

Ka mahi a Shingrix mā te whakangungu i tō pūnaha ārai mate ki te mōhio me te whawhai i te huaketo varicella-zoster i te pai ake. Kei roto i te kano ārai mate he pūmua motuhake (glycoprotein E) mai i te huaketo e ako ana tō pūnaha ārai mate ki te tautuhi he mea ke.

Inā honoa ki te adjuvant AS01B, ka whakaoho tēnei pūmua i te urupare ārai mate kaha e uru ana ki ngā paturopi me ngā pūtau T. He mea nui tēnei whakamarumaru rua nā te mea ka heke te ārai mate pūtau T i te pakeketanga, koinei te take e kaha ake ai ngā pakeke ki te shingles.

E kiia ana he tino kaha me te whai hua tēnei kano ārai mate, e whakarato ana i te neke atu i te 90% te whakamarumaru ki te shingles i ngā whakamātau haumanu. Ka mau tonu te whakamarumaru ahakoa i ngā tāngata neke atu i te 70 tau te pakeke, e whai hua ana i te nui atu i te kano ārai mate zoster ora tawhito kāore i te taunakitia.

Me pēhea taku tango i te kano ārai mate Zoster?

Ka tukuna a Shingrix hei werohanga ki roto i te uaua o tō ringa o runga e tētahi kaiwhakarato hauora. Kāore koe e hiahia ki te tango me te kai, te wai rānei i te mea he werohanga, ehara i te rongoā waha.

E hiahia ana koe kia rua ngā horopeta o te kano ārai mate, me te horopeta tuarua ka tukuna 2-6 marama i muri i te horopeta tuatahi. He mea nui kia whakaoti i ngā horopeta e rua kia mōhio ai te whakamarumaru nui. Ki te tatari koe neke atu i te 6 marama i waenga i ngā horopeta, kāore koe e hiahia ki te tīmata anō i te raupapa – me tiki noa tō horopeta tuarua i te wā e taea ai.

I mua i tō kōtuinga, mau he hāte he rākau e taea te huri ake. Ka taea e koe te kai noa i mua me muri i tō werohanga, ā, kāore he here kai motuhake e pā ana ki tēnei kano ārai mate.

Kia Pēhea te Roa e Tango ai au i te Kano Ārai Mate Zoster?

Ko te kano ārai mate zoster he raupapa e rua ngā horopeta ka whakaotihia e koe i roto i ngā marama maha, ehara i te rongoā e haere tonu ana e tango ana koe i ia rā. Kia whiwhi koe i ngā horopeta e rua, ka whakaarohia koe kua tino werohia ki te shingles.

E whakaatu ana te rangahau o nāianei e kaha tonu ana te whakamarumaru mai i te Shingrix mō te 7 tau i muri i te werohanga. Kei te haere tonu ngā rangahau ki te whakatau i te roa o te ārai mate, engari kāore pea koe e hiahia ki ngā pūhi whakakaha mō ngā tau maha, ki te hiahia rānei.

Kāore i rite ki ētahi kano ārai mate e hiahia ana ki ngā pūhi whakakaha ā-tau, ko te urupare ārai mate kaha i hangaia e Shingrix te ahua nei ka whakarato i te whakamarumaru roa. Ka whakamōhio tō kaiwhakarato hauora ki a koe mō ngā tūtohutanga mō ngā horopeta whakakaha i te wā e wātea ana te rangahau.

He Aha ngā Pānga Taha o te Kano Ārai Mate Zoster?

Ko te nuinga o te tangata ka pā ki ētahi pānga taha ngawari ki te āhua i muri i te whiwhinga i te Shingrix, e tohu ana tēnā e pai ana te urupare a tō pūnaha ārai mate ki te kano ārai mate. Ko ēnei pānga taha te nuinga ka roa 2-3 rā, ā, he ngawari te whakahaere ki ngā rongoā mamae e hokona ana.

Koinei ngā pānga taha tino noa ka pā ki a koe, tata ki te raupapa mai i te nuinga ki te iti:

• Te mamae, te whero, te pūhi rānei i te wāhi werohanga (e pā ana ki te 8 i roto i te 10 tangata)
• Ngā mamae uaua me te ngenge (e pā ana ki te 4-5 i roto i te 10 tangata)
• Te ānini (e pā ana ki te 4 i roto i te 10 tangata)
• Te kirika me te wiri (e pā ana ki te 2-3 i roto i te 10 tangata)
• Te whakapairuaki me te pōpōtanga o te puku (e pā ana ki te 1-2 i roto i te 10 tangata)

He kaha ake te nuinga o ēnei urupare i muri i te horopeta tuarua, ā, he nui ake te kitea i roto i ngā pakeke taitamariki. Ahakoa te kore e pai, he tohu tēnei kei te hanga tō pūnaha ārai mate i te whakamarumaru ki te shingori.

He onge ngā pānga taha kino, engari ka uru pea ki ngā urupare pāwera nui. Mēnā ka raru koe ki te manawa, te pūhi o tō mata, o tō korokoro rānei, he pūhi kino rānei, me rapu tonu koe i te āwhina hauora. Ka pā pea te whara o te pakihiwi e pā ana ki te whakahaere i te kano ārai mate (SIRVA) ki ētahi tāngata, ahakoa he mea noa tēnei ina tika ana te werohanga.

Ko wai kāore e tika kia tango i te kano ārai mate Zoster?

Ka taea e te nuinga o ngā pakeke te tango i te Shingrix, engari he mea nui ētahi mea hei whakaaro. Kaua koe e tango i tēnei kano ārai mate mēnā i pāwera koe ki tētahi wāhanga o te kano ārai mate, ki tētahi horopeta o mua o te Shingrix rānei.

Me karo hoki koe i te kano ārai mate mēnā kei te pā koe i tētahi mate āhua kino ki te kino me te kirika. Ahakoa e kore te makariri iti e aukati i te werohanga, he pai ake te tatari kia pai ake koe kia mōhio tika ai koe ki ngā pānga taha e pā ana ki te kano ārai mate.

Mēnā kei te hapū koe, kei te whāngai u rānei, me tatari koe ki te tango i te Shingrix kia oti ra anō te hapūtanga me te whāngai u. Ahakoa kāore he tohu o te kino, kāore he raraunga haumaru i roto i ngā wahine hapū hei tūtohu i te whakamahi i ia rā.

Ko ngā tāngata e tango ana i ētahi rongoā e tino pēhi ana i te pūnaha ārai mate me kōrero ki tō rātou kaiwhakarato hauora mō te wā tika. Ahakoa e tūtohutia ana te kano ārai mate mō ngā tāngata e ngoikore ana te pūnaha ārai mate, ka hiahia pea tō tākuta ki te whakatika i te wā tika i runga i tō hōtaka maimoatanga.

Ngā Ingoa Waitohu o te Kano Ārai Mate Zoster

Ko Shingrix te ingoa waitohu mō te kano ārai mate zoster recombinant i hangaia e GlaxoSmithKline (GSK). Koinei anake te kano ārai mate zoster e tūtohutia ana e te CDC mō ngā pakeke 50 tau me te pakeke ake.

Ka rongo pea koe mō Zostavax, te kano ārai mate zoster tawhito, engari kāore i te wātea i Amerika i te tau 2020. Ki te mea i whiwhi koe i te Zostavax i mua, me whiwhi tonu koe i te Shingrix mō te whakamarumaru pai ake.

I te wā e whakarite ana i tō hui, pātai noa mō te "kano ārai mate shingles" rānei "Shingrix" – ka mōhio ngā kaiwhakarato hauora ki tāu e kōrero ana. Ko te nuinga o ngā whare rongoā, ngā tari tākuta, me ngā hōhipera hauora e mau ana i tēnei kano ārai mate.

Ngā Kōwhiringa Kano Ārai Mate Zoster

I tēnei wā, kāore he kano ārai mate kē atu ki te Shingrix mō te ārai i te shingles. Ko Shingrix anake te kano ārai mate shingles e wātea ana, e tūtohutia ana i Amerika mai i te wā i whakamutua ai te Zostavax.

Ki te kore e taea e koe te whiwhi Shingrix nā te mate pāwera, ētahi atu take hauora rānei, kāore ētahi atu kano ārai mate e wātea ana. Heoi, ki te whanake koe i te shingles, ka taea e ngā rongoā antiviral pēnei i te acyclovir, valacyclovir, famciclovir rānei te āwhina i te whakaiti i te kaha me te roa o ngā tohumate i te wā e tīmata wawe ana.

E pātai ana ētahi tāngata mō ngā kōwhiringa tūturu, ngā tāpiringa rānei, engari kāore he hua tūturu i whakamatauria hei ārai i te shingles me te whai hua rite ki te Shingrix. Ko te pupuri i te hauora pai, te whakahaere i te pēhanga, me te moe pai pea e tautoko ana i tō pūnaha ārai mate, engari kāore ēnei mahi anake e whakarato i te whakamarumaru motuhake e tukuna ana e te kano ārai mate.

He Pai Ake Anei te Shingrix i te Zostavax?

Āe, he nui ake te whai hua o te Shingrix i te kano ārai mate Zostavax tawhito. Ahakoa i whakarato te Zostavax i te 50% te whakamarumaru ki te shingles i roto i ngā tāngata 60-69 tau te pakeke, ka tukuna e te Shingrix te neke atu i te 90% te whakamarumaru puta noa i ngā rōpū tau katoa, tae atu ki te hunga neke atu i te 70.

Ka whakarato hoki te Shingrix i te whakamarumaru pai ake ki te neuralgia postherpetic, te āhua mamae mau tonu ka whai i te shingles. E whakaatu ana ngā rangahau ka whakaiti te Shingrix i te tūponotanga o te PHN i te neke atu i te 90%, ka whakataurite ki te 67% te whakaiti me te Zostavax.

Ka roa ake ano te whakamarumaru mai i te Shingrix. Ahakoa i tino heke te whai huatanga o Zostavax i muri i te 5 tau, ka mau tonu te whai huatanga o Shingrix mo te 7 tau neke atu ranei. Koinei te take i whakakapi ai nga mana hauora i te Zostavax ki te Shingrix.

Ahakoa i whiwhi koe i te Zostavax i mua, me whiwhi tonu koe i te Shingrix kia pai ake ai te whakamarumaru. Ka taea e koe te whiwhi Shingrix i nga wa katoa i muri i te whiwhinga o Zostavax – karekau he wa tatari e hiahiatia ana.

Nga Pātai e Pātai pinepine ana mō te kano ārai mate Zoster

He haumaru te Shingrix mō te hunga mate huka?

Ae, he haumaru te Shingrix, he mea nui rawa atu mō te hunga mate huka. Ka taea e te mate huka te whakaiti i tō pūnaha ārai mate, ka nui ake te tūponotanga ki te shingles me ōna raruraru.

Ko te hunga mate huka e whakawhanake ana i te shingles ka nui ake pea ngā tohumate me te roa ake o te wā whakaora. E whakarato ana te kano ārai mate i te whakamarumaru pai i roto i te hunga mate huka me te hunga kāore, nā reira he mahi ārai mate pai te kano ārai mate. Kāore e tika kia pā te kano ārai mate ki ō taumata huka toto, ahakoa me mātakitaki koe i ō taumata mō ētahi rā i muri i te kano ārai mate mena he pai tō whakahaere i te kūkū.

Me aha au mēnā ka whiwhi au i te nui rawa o ngā horopeta o Shingrix?

Mēnā ka whiwhi koe i tētahi horopeta anō o Shingrix, kaua e mataku – kāore tēnei e whara nui. Whakapā atu ki tō kaiwhakarato hauora ki te pūrongo i te horopeta anō me te kōrero mō ō āwangawanga.

Ka nui ake pea ō pānga taha i te tikanga, pēnei i te nui ake o te mamae i te wāhi werohanga, i ngā tohumate rite te rewharewha rānei. Me whakaoti ēnei i roto i ngā rā torutoru. Kia mau ki te wā i whiwhi ai koe i ia horopeta kia tika ai te wātea o ngā kano ārai mate a muri ake nei. Ka taea e tō kaiwhakarato hauora te āwhina i a koe ki te whakatau mēnā e hiahiatia ana ētahi whakatikatika ki tō hōtaka kano ārai mate.

Me aha au mēnā ka ngaro taku horopeta tuarua o Shingrix?

Mēnā ka ngaro i a koe tō horopeta tuarua o Shingrix, whakaritea i te wā e taea ai. Kāore koe e hiahia ki te tīmata anō i te raupapa – me tiki noa tō horopeta tuarua i te wā e taea ai e koe, ahakoa kua roa ake i te 6 marama mai i tō horopeta tuatahi.

Ahakoa ko te wā i waenga i ngā horopeta e rua ki te ono marama, ko te whiwhi i te horopeta tuarua i muri i te wā i whakaritea e kore e whakaiti i tōna whai huatanga. Ka pai tonu te urupare a tō pūnaha ārai mate ki te horopeta tuarua kua roa. Heoi, e kore koe e whai whakamarumaru katoa ki te shingrix kia oti ra anō i a koe ngā horopeta e rua, no reira kaua e whakaroa noa.

Āhea ka mutu taku māharahara mō te Shingles i muri i te whiwhi i te Shingrix?

Ka taea e koe te whai whakaaro mō tō whakamarumaru shingrix tata ki te 2-4 wiki i muri i te whiwhi i tō horopeta tuarua o Shingrix. Koinei te wā i tino urupare ai tō pūnaha ārai mate ki te kano ārai mate, ā, kua hanga te whakamarumaru mōrahi.

Neke atu i te 90% te whakamarumaru o te kano ārai mate, ko te tikanga he iti rawa tō tūponotanga ki te whakawhanake i te shingrix. Heoi, kia mahara kāore he kano ārai mate he 100% whai hua, no reira kei te noho tonu te tūponotanga iti o te shingrix. Mēnā ka whakawhanake koe i te shingrix i muri i te kano ārai mate, he māmā ake pea, he poto ake i te mea ka pēnei me te kore he kano ārai mate.

Ka taea e au te tiki Shingrix mēnā kei te tango au i ngā whakaiti toto?

Āe, ka taea e koe te whiwhi haumaru i te Shingrix mēnā kei te tango koe i ngā whakaiti toto pēnei i te warfarin, apixaban, rānei, te aspirin. Ka tukuna te kano ārai mate hei werohanga intramuscular, ā, ahakoa he iti ake pea te pānga i te wāhi werohanga, kāore tēnei i te mōrearea.

Tohua tō kaiwhakarato hauora mō ō rongoā whakaiti toto i mua i te kano ārai mate. Ka pēhi pea rātou i te wāhi werohanga mō te wā roa ake i te tikanga hei whakaiti i te pānga. Ko ngā painga o te ārai shingrix he nui ake i te tūponotanga iti o te piki ake o te pānga, ina koa kei te tūpono pea ngā tāngata e tango ana i ngā whakaiti toto ki ngā raruraru shingrix.