Āe, ka taea e Augmentin te whakaora i te mate mimi, engari he rongoā tuarua tērā. E tohua ana e te FDA te amoxicillin/clavulanate mō ngā pākū tōtika i puta mai i ngā huakita e whakaputa ana i te beta-lactamase, ā, kei mua tonu i tēnei rongoā te nitrofurantoin, te trimethoprim-sulfamethoxazole me te fosfomycin mō ngā mate pukupuku noa. Ko te tikanga, ka rima ki te whitu ngā rā te roa o te rongoā mō te pakeke.

Kōrero Tere: Ngā Take Nui

  • Ka whakaora a Augmentin i ngā mate mimi, engari ka tohua e te IDSA me te ESCMID hei rongoā whakakapi, ehara i te mea tuatahi, mō te cystitis kāore nei he raruraru.
  • I roto i ngā raraunga whakataetae o muri mai i tērā tohutohu, i whakaora te rongoā 3-ra te roa o te amoxicillin/clavulanate i te 58% o ngā wāhine i te taha ki te 77% mō te ciprofloxacin.
  • Tata ki te 43% o ngā huakita E. coli o te UTI noa o waho e ātete ana ki ngā rongoā o te whānau penicillin, ā, i raro iho i te 1% ki te nitrofurantoin.
  • Koinei te kōwhiringa tika mēnā he ahurea aukati, he mate pāwera ki te hūpō, ka whakarerea te nitrofurantoin, ka whai tamariki rānei, kei reira ngā beta-lactam hei kōwhiringa tuatahi.
  • Ko te horopeta pakeke kua tohua ko te 500 mg ia 12 haora, ko te 250 mg rānei ia 8 haora, nā te 5 ki te 7 rā te roa mō te cystitis. Ko te tākuta e tohutohu ana i te horopeta.

Āe, ka taea e Augmentin te whakaora i te mate mimi, engari he iti rawa te kōwhiringa tuatahi

Ka taea e Augmentin te whakaora i te mate mimi? Āe, engari me tētahi atu. E tohua ana te amoxicillin/clavulanate e te FDA mō ngā pāpāku tōtika i puta mai i ngā momo huakita e whakaputa ana i te beta-lactamase pēnei i te E. coli, Klebsiella me Enterobacter, ā, ka whakaora tonu tēnei i ngā mate pukupuku. Engari, kei muri iho i ngā rongoā e toru hei rongoā noa i te cystitis, nā reira ko te mea tika rawa atu hei kōwhiringa ina teka te mahi o aua rongoā.

Kāore te clavulanate e mahi hei rongoā anō i a ia anō. Ka aukati tēnei i te whākoka beta-lactamase e whakamahia ana e ngā huakita aukati ki te whakangaro i te amoxicillin, ā, koinei te take e taea ai e te huinga te toro atu ki ngā iroriki kāore e taea e te amoxicillin noa. He pono tēnei kaha, ā, kāore tonu i te rahi kia waiho hei rongoā tuatahi: E kii ana te IDSA me te ESCMID ko te amoxicillin/clavulanate he rongoā whakakapi tuarua mō te cystitis noa, kāore nei he raruraru. Ko te wāhanga e whai ake nei te taunakitanga.

Tuarua mō te Take: Ka iti ake te whakaora a Augmentin i ngā mate mimi i ngā rongoā e whakakapi ana ia

Ko ngā tohutohu IDSA/ESCMID o te tau 2011 mō te cystitis noa, kāore nei he raruraru, e whā ngā rongoā matua: nitrofurantoin, trimethoprim-sulfamethoxazole, fosfomycin, me te pivmecillinam ki te wātea ki Uropi. Kei te taha whakakapi te amoxicillin/clavulanate, hei tērā wā ka kore e taea te whakamahi i ngā rongoā matua. He tikanga tēnei, ehara i te whakakore.

Ko ngā tatauranga o muri mai i te tikanga he koretake. I roto i te whakataetaenga i whakahuatia i roto i taua tohutohu, ko te amoxicillin/clavulanate 500/125 mg rua i te ra mō te 3 rā ka eke ki te 58% te whakaora katoa ki te 77% mō te ciprofloxacin, me te whakaora iroriki 76% ki te 95%. Kia mahara ki te roa. Ko taua rongoā 3-ra te roa, he poto ake i te tikanga o te rongoā mō te cystitis i ēnei rā.

Ka nui ake te rerekētanga o te aukati. I roto i tētahi raraunga nui o ngā tari hauora i Amerika, i whakaputaina i te Open Forum Infectious Diseases i te tau 2023, ko ngā momo E. coli o te UTI noa ka tata ki te 43% te aukati ki ngā rongoā o te whānau penicillin, te rōpū e uru ana te amoxicillin/clavulanate, ki raro iho i te 1% te aukati ki te nitrofurantoin.

Ko te mea kāore ngā whārangi e kii ana: kāore tēnei e kii ana kua kino te Augmentin. He rongoā pai tēnei mō ngā mate o te ihu, te taringa, te ngau me te pūkahukahu. Ko te 43% he kohinga ā-motu, ā, ko te tauira aukati o tō rohe me tō ake ahurea te mea nui ake i ngā tauira whakaputa. Ko te kōrero kei te raupapa noa, mō tētahi mate motuhake, ehara i te mea atu.

E whā ngā āhuatanga e huri ai te kōwhiringa ki a Augmentin

Ko te Augmentin mō te mate mimi i te wā e hapū ana, ko tētahi o ngā whā ngā āhuatanga hei kōwhiringa tika mā te rongoā tuarua. Ko te toru atu ko te ahurea aukati, te mate pāwera ki te hūpō, me te mate whatukuhu, te wāhi o te mate rānei ka aukati i te nitrofurantoin.

  • Ko te ahurea te kii. E whakaatu ana te ahurea mimi me te pūrongo aukati i tētahi iroriki whakaputa beta-lactamase e aukati ana ki te rongoā tuatahi i whakamātau kē koe.
  • Kāore te hūpō. Ko te mate pāwera ki te hūpō, te kore e kaha ki te kōwhiri, ka aukati i te trimethoprim-sulfamethoxazole katoa.
  • Kāore te nitrofurantoin. Ko te iti o te mahi whatukuhu, te mate rānei kua whakapae ki runga ake i te pukupuku, ka waiho hei taputapu he.
  • Te hapūtanga. I te 2025 JAMA Network Open study neke atu i te 71,000 ngā hapūtanga tuatahi, i kitea ko te trimethoprim-sulfamethoxazole he nui ake te tupono o te whānautanga kē atu i te beta-lactams (tupono 1.35), ā, ko te nitrofurantoin me te fluoroquinolones i rite ki te beta-lactams.

Panuitia ngā kupu tuawhā kia tino mārama. E tautoko ana tēnei i te kii ko ngā beta-lactams hei momo matua i te timatanga o te hapūtanga, ehara i te kii ko Augmentin "haumaru i te hapūtanga". Ko te tākuta me te marama e whakatau ana. Me te kite hoki, e toru o ngā whā ngā take ka whakawhirinaki ki te hua o te ahurea, te tikanga ko tēnei he rārangi hei whakarite ki tō rekoata, ehara i te pātai ki a koe anō.

Mēnā kei a koe ngā tohu, ā, kāore anō he mahere, ko te $39 te utu o te tari ohorere ipurangi me August ka hono koe ki tētahi tohunga rongoā kua rēhitatia ki te US ka taea te aromatawai i ō tohu, tono whakamātautau me te whakahaere mena e tika ana. Ko te tohunga te whakatau mena ka hiahiatia he rongoā, me te aha hoki, nā reira kāore he rongoā e taurangi ana. Kāore hoki e taea e tētahi tari te whakahaere i te mate whatukuhu kua whakapae, te whakakapi rānei i te tirotiro tinana ina kei reira ngā tohu whakatūpato.

Ko te horopeta te haurua o te whakahaeretanga. Ko te roa te haurua atu.

Ko te horopeta Augmentin mō te mate mimi i runga i te tohutohu FDA mō ngā pakeke ko te kotahi papa 500 mg ia 12 haora, ko te kotahi papa 250 mg rānei ia 8 haora, me te 875 mg ia 12 haora te tikanga mō ngā mate tino nui.

Ko te rerenga e tika ana kia korerotia ki tō kaihoko rongoā, ko te huinga o te horopeta me te roa: mō te cystitis noa, 500/125 mg ia 12 haora (ko te 875/125 mg rānei ia 12 haora mēnā ka whakaaro te tākuta he tino nui te mate) mō te 5 ki te 7 rā, ehara i te 3-ra te roa nā te mea i raro iho te mahi i roto i ngā whakataetae. Mēnā ka hiahia koe ki te take mō te te roa o te tango Augmentin, kei te wāhi o te mate me te kaha o taua mate te take.

Ka whakarerekē te mahi o te whatukuhu i te tatauranga. E ai ki te tohutohu, kāore te papa 875 mg e tika ana kia whakamahia i te wā he raro iho i te 30 mL/min te horoi o te creatinine, ā, ka heke te horopeta ki te tata ki te 250 ki te 500 mg ia 12 haora mō te 10 ki te 30 mL/min te horoi o te creatinine, ā, ia 24 haora ki raro iho i te 10. Kei te tākuta te whakarerekētanga. Kāore rawa e taea e koe anō te whakarerekē.

E rua ngā kōrero mahi ka pā ki te pai o te manawaro o te horopeta Augmentin mō te mate mimi. E kii ana a MedlinePlus kia tangohia ia 8 ki te 12 haora me te kai, te paramanawa rānei hei whakaiti i te mamae o te puku, ā, e whakatūpato ana hoki ko te amoxicillin/clavulanate ka taea te whakaiti i te whai hua o ngā rongoā ā-waha mō te hapūtanga, nā reira me whakamahi he tikanga whakakapi i te wā e rongoā ana.

Ki te taha ki a Macrobid me Bactrim, ka ngaro a Augmentin i ngā āhuatanga katoa engari kotahi

Ko te Augmentin ki te Macrobid mō te mate mimi, ko te Augmentin ki te Bactrim mō te mate mimi, koinei ngā whakataetae e rua e mahia ana e ngā tāngata, ā, ka tere te whakaoti tahi i tērā ki tērā. Ko te Nitrofurantoin te rongoā tuatahi, i raro iho i te 1% te aukati E. coli i roto i ngā raraunga o te tau 2023, engari ka kuhu ki te mimi, kāore hoki e tae atu ki te taumata tiketike o te kiko i waho o te pukupuku. Tirohia tēnei hei ture uaua: kāore e ranea mō te pyelonephritis. Ko te Trimethoprim-sulfamethoxazole hoki te rongoā tuatahi ki te mōrearea teitei o te aukati o te rohe, ā, ko te mate pāwera ki te hūpō ka kati katoa tērā tatau. Ko te Fosfomycin te rongoā tuatahi hei kōwhiringa kotahi te horopeta. Ko tā mātou whakataetae o Bactrim vs Macrobid ka nui ake te kōrero mō aua tokorua.

Ko te painga pono o Augmentin he whāiti engari he pono: he rongoā beta-lactam ina kua kati te mate pāwera, te hapūtanga, te ahurea aukati rānei i ngā tatau tuatahi, ka whakaritea ki te tata ki te 43% te aukati o te whānau penicillin.

Anei te kōrero kāore he whārangi whakataetae e kii ana. Ka aukati te mate whatukuhu i te nitrofurantoin, engari kāore e piki tonu a Augmentin. E kii ana te IDSA guideline nei anō he iti ake te whai hua o ngā beta-lactams ā-waha i ngā rongoā kē atu mō te pyelonephritis, ā, mēnā ka whakamahia, me whai i te rongoā tuatahi ā-waha o tētahi rongoā roa pēnei i te ceftriaxone me tētahi aminoglycoside.

Ko te kirika me te mamae o te taha ka kii kua puta ke te pātai rongoā

Ko ētahi tohu ka waiho te kōrero Augmentin-ranei-kāore rānei hei kōrero koretake, nā te mea ka whakarereke te wāhi o te manaaki, ehara i te kōwhiringa o te pire.

Waea mai ki te 911, haere rānei ki te tari ohorere ināianei mēnā:

  • Te raruraru o te hinengaro, te manawa tere, te tere o te ngākau, te iti rānei o te pehanga toto me te mate mimi kua whakapae, ka tohu pea te urosepsis
  • Te pupuhi o te mata, te korokoro, te arero, te ngutu, te kanohi rānei, te uaua ki te manawa, te horomia rānei, te ngāwhiwhi rānei, ka tohu pea te mate pāwera nui
  • Te kōwhai o te kiri, te karu rānei, te mimi pouri, te mamae rānei o te puku matau o runga, ka tohu pea te kino o te ate

Ko te taumata e whai ake nei ehara i te ohorere, engari ehara hoki i te tatari noa. Ko ngā tohu katoa o te mate mimi me te kirika i te wā e hapū ana, me āta tirotiro wawe.

Whakaritea he wā o te wiki nei mēnā:

  • Ko te kirika, te makariri, te mamae o te taha, te tuarā rānei o raro, te ruaki rānei me te mate mimi, ka tohu pea he mate whatukuhu me āta tirotiro wawe tonu.
  • Kāore ngā tohu e pai haere ana i raro i te rongoā
  • Te mimi wai, te toto rānei me te mamae o te puku me te kirika i te wā o te rongoā, tae atu ki te rua marama i muri i te whakamutu, e ai ki a MedlinePlus ka tohu pea he korikori C. difficile. He pono taua whakaroa, nā reira me whakauru ngā rongoā tata nei, ahakoa kua maha marama kua pahure.

A ko ētahi mea e tika ana kia korerotia i mua i te tango i te papa tuatahi, me ngā āhuatanga kino o Augmentin.

Kōrero ki tētahi tohunga i mua i te tīmatanga mēnā:

  • Kei a koe te mate pāwera ki te penicillin, te urupare kino rānei o te ate ki te amoxicillin/clavulanate i mua
  • Kua iti te mahi o tō whatukuhu
  • Kei te hapū koe, kei te whāngai koe, ā, kei te whakawhirinaki koe ki ngā rongoā ā-waha mō te hapūtanga

Ngā Pātai Auau

Ka taea e au te tango i te Augmentin tawhito kua toe mō te mate mimi?

Kāore. Ko te pounamu kāore i oti, ko te tikanga he rongoā kāore i oti, ā, i tohua mō tētahi mate kē atu, ā, pea hoki he iroriki kē atu. Ko te tango i etahi rā o te beta-lactam ka mate pea te iroriki o nāianei ki te aukati, ka whakatairanga ake i te aukati, ka whakapouri i te ahurea mimi mēnā ka whiwhi koe i muri mai, ā, ka whakaroa te rongoā whai hua. Me āta tirotiro te mate o nāianei me te whakahaere rongoā tika.

Kia hia te tere ka tīmata te mahi a Augmentin mō te mate mimi?

Nō reira, i roto i te 24 ki te 48 haora, ka tino mārama te whakaheke o te wera me te hiahia ki te mimi. Mēnā kāore he pai haere i te 48 ki te 72 haora, ka kino rānei ngā tohu i tētahi wā, whakapā atu ki tō tākuta kaua e tatari kia mutu te rongoā. Ko taua tauira te tikanga kua aukati te iroriki, ā, me ārahi te ahurea i te panoni. Me whakaoti te rongoā katoa i whakahaeretia, ahakoa kua pai kē te ahua.

He aha te raruraru o ngā arotake a ngā tūroro ipurangi mō Augmentin mō te mate mimi?

I ētahi wā kāore noa i rite te rongoā ki te iroriki. Ka wehea ngā arotake tata ki te rite te wehewehe nā te mea ko te hua ka whakawhirinaki ki te āhua o te momo E. coli nei, ā, ko te aukati o te whānau penicillin i roto i ngā momo mate mimi o waho ka tata ki te 43%. I whakahaeretia i runga i te pūrongo aukati, he pai te mahi. I whakahaeretia kāore i te mōhio, he maha ngā tāngata kāore e whai hua, ka tuhituhi hoki mō taua mea.

He pai kē atu te amoxicillin noa i te Augmentin mō te mate mimi?

Kāore. Kāore e taea te whakakapi tērā tokorua. Ko te tohutohu a te FDA ko te mea motuhake mō ngā momo whakaputa beta-lactamase, ā, ko aua huakita ka whakaputa te whākoka e whakangaro ana i te amoxicillin i whakamahia anō. Kei te herea te clavulanate ki te aukati i taua whākoka. Kua heke rawa te amoxicillin anō i roto i te pono ki te urinary E. coli, kāore hoki e tika ana hei rongoā matua mō te cystitis.

Ka mahi kē atu a Augmentin mō te mate mimi i ngā tāne, mō te hunga rānei he ngongo mimi?

I ētahi wā, engari ka puta kē ēnei i ngā mea katoa i runga ake nei. Ko ngā mate mimi i ngā tāne, i te hunga he ngongo mimi, me te hunga kua pakaru te pūngao mimi, ka kiia he tino nui, te tikanga ko te ahurea mimi he mea nui, ka roa te rongoā, ā, ka taea te whakakapi te tango rānei i te ngongo mimi. Ko te horopeta me te roa o te rongoā i runga i tēnei whārangi e kii ana mō te cystitis kāore nei he raruraru.

Ko te mutunga mō Augmentin me ngā mate mimi

He whai hua a Augmentin ki ngā mate mimi, ā, kei te tuarua tonu te taumata mō te cystitis noa, kei muri i te nitrofurantoin, te trimethoprim-sulfamethoxazole me te fosfomycin. Ko Augmentin mō te mate mimi ka waiho hei rongoā tika ina kati te hua o te ahurea, te mate pāwera ki te hūpō, te mahi whatukuhu, te hapūtanga rānei i ngā tatau tuatahi. Ina tohua, ko te huinga e whai kiko ana ko te horopeta me te roa: 500/125 mg ia 12 haora mō te 5 ki te 7 rā i roto i te cystitis noa, hei tohutohu mā tō tākuta. Ko te tohutohu i raro i te ahurea te mea e wehewehe ai ngā hua pai i ngā hua kino e kōrerohia ana e te tangata i roto i ngā arotake.

Whakakāhore: Ko tēnei tuhinga mō ngā kōrero mōhiohio anake, ā, kāore e kiia hei tohutohu hauora. Me whakapā atu tonu ki tētahi tohunga hauora whai raihana mō ngā whakatau tātaritanga me te rongoā. Mēnā kei te wheako koe i tētahi ohorere hauora, waea mai ki te 911, haere rānei ki te tari ohorere tata tonu atu.