He pono te whakatūpato mō te metronidazole me te waina, engari he iti te taunakitanga: e kii ana te tapanga a te FDA kia karohia te waina i te wā o te rongoā, me ngā rā e toru i muri i tō pū rongoā whakamutunga, ā, e kii ana te CDC kāore he take kia whakarērea. E mau tonu ana ēnei kōrero. Mō te wā poto o te rongoā, ko te tatari te whakatau mārama.
TL;DR: Ngā Mea Nui Kia Mahara
- E kii ana te tapanga a te FDA kia kaua he waina i te wā o te rongoā, me ngā rā e toru i muri i te pū rongoā whakamutunga.
- E kii ana ngā aratohu rongoā a te CDC mō te metronidazole, kāore he take kia whakarērea, ā, iti te taunakitanga mō te pānga ki waenga i te metronidazole me te waina.
- Kāore te metronidazole e aukati i te whākawa disulfiram e aukati nei, nā reira he kupu teka te "rite ki te disulfiram".
- Ki te inu kē koe, tēnā pea kāore he aha, tēnā pea he ngāwari te whero o te kiri me te māuiui ka mutu anō māna.
- Kaua rawa e mutu te rongoā paturopi nā te mea kua inu koe i te waina.
Kia noho tawhiti i te waina i te wā kei te tango koe i te metronidazole, engari ehara i te mea he kino
Ko te aratohu mana mō te metronidazole me te waina, he mārama: ko te tapanga kua whakaaetia e te FDA, kua whakahoutia Pēpuere 2022, e whakatūpato ana ko te metronidazole ā-waha e pā ana ki te tauhohenga ki te waina ka rite ki te disulfiram, tae atu ki te mamae o te puku, te māuiui, te ruaki, te mamae o te upoko, me te whero o te kiri. E kii ana kia mutu te inu waina me ngā hua kei roto te propylene glycol i te wā o te rongoā, me te 3 rā i muri atu i tō pū rongoā whakamutunga.
MedlinePlus, te rauemi rongoā a te Whare Wānanga o te Motu mō ngā tūroro, e whakahoki ana i taua tohutohu 3-rā i roto i ngā kupu ngāwari ake. Ko ngā mea katoa kei tēnei wāhanga e pā ana ki ngā papa me ngā kapote ā-waha, ko tēnei anō te tikanga ina rapua e te tangata te Flagyl me te waina, nā te mea ko te Flagyl he metronidazole noa iho i raro i tō ingoa waitohu tuatahi.
He mea nui kia mōhiohia i mua i te mataku o te katoa: ko te tauhohenga e whakaahuatia ana e ngā tapanga nei, i ngā wā ka puta mai, he kino kē atu i te whakatumatuma ora. He pō kino tērā, ehara i te haerenga ki te rūma ohorere.
E kii ana te CDC kāore he take kia karohia te waina i te wā kei te tango koe i te metronidazole
Ko te pūrākau mō te metronidazole me te waina ehara i te mea kāore e taea te tauhohenga, engari kāore te whakatūpato i hangaia i runga i te whenua pakari. E kii ana te CDC i roto i ngā Aratohu Rongoā STI i kitea e te arotake "kāore he rangahau in vitro, he tauira kararehe, he pūrongo mō ngā pānga kino, he rangahau rānei e whakarato ana i te taunakitanga whakapono o te tauhohenga rite ki te disulfiram i waenga i te waina me te metronidazole," ā, ka mutu ko "te whakarērea i te kai waina i te wā kei te tango koe i te metronidazole (tērā rānei te tinidazole) kāore he take."
Ko ngā raraunga whakahaere e whakaatu ana i te ara kotahi. I roto i tētahi arotake i whakaputaina ki Antimicrobial Agents and Chemotherapy, ka whakaahuatia e Mergenhagen me āna hoa tētahi rangahau matapōkere, ā, ko tētahi i whakahaerea mā te placebo i roto i ngā kaiuru 12, ka kitea kāore he rereketanga o ngā taumata aldehyde dehydrogenase i waenga i ngā rōpū, ā, kāore hoki he tohu hinengaro o te tauhohenga rite ki te disulfiram. Ko tā rātou panuitanga i te tuhinga whānui, he iti te taunakitanga, he tauwhitiwhiti hoki, ā, ko te tauhohenga, ki te pūrongohia katoatia, ka puta "i te auau kāore i te tino mārama" me te "taumaha rerekē".
Nā reira, nō hea i ahu mai ai te ture? E kii ana te CDC i ahu mai i ngā whakamātau taiwhanga me ngā kōrero take i roto i tērā ka taea "kia rite te puta mai i te waina anake, tērā rānei i ngā pānga kino o te metronidazole". I tētahi arotake take i roto i te hautaka Emergency Medicine News, e ono noa iho ngātake kua pūrongohia, e pā ana ki waru tūroro, i roto i ngā tau 1964 ki 1999. Ko ngā whakatūpato paturopi whānui pērā te whakakaha, koinei hoki te kōrero i muri i te cephalexin me te waina.
Ko te raruraru: he kupu poto tika te kii he pūrākau te metronidazole me te waina, engari ehara te taunakitanga iti i te taunakitanga o te haumarutanga. Kāore ngā tekau mā rua o ngā kaitautoko e eke ki te whakakore i tētahi tauhohenga onge, ā, ko te rangahau nui hei whakatau i tērā kāore anō kia whakahaeretia.
Ko te "rite ki te disulfiram" he kupu teka: ko te kino tūtahi o te disulfiram ko te rongoā tonu
Ko te tauhohenga rite ki te disulfiram e tika ana kia puta mai i te metronidazole he tikanga motuhake, ā, kāore te metronidazole e whakamahi ana i tērā. I roto i tētahi tauhohenga disulfiram tūtahi, ka huri te waina ki te acetaldehyde ā, ka noho ki reira, nā te mea ka aukatihia te whākawa aldehyde dehydrogenase. Ka kohikohi te acetaldehyde, ā, ka whiwhi koe i te whero, te pāhū o te ngākau, te māuiui, me te ruaki.
Ehara ko tērā te mahi a te metronidazole. E kii ana te CDC, mārama, ko te metronidazole "kāore e aukati i te acetaldehyde dehydrogenase, pera i te disulfiram". Ko te kōrero a ngā tākuta i Medscape, e ōrite ana ki ngā tuhinga arotake, e kii ana ki te aukati i te alcohol dehydrogenase, e whakaiti ana i te pakanga o te waina, kaua ki te whakaputa i te piki nui o te acetaldehyde. Ko te ingoa e mau ana i te rite o ngā tohu, ehara i te rite o te koiora.
I tērā wā, he tauhohenga disulfiram kei runga i te tapanga e tino taunakitia ana. Kāore te metronidazole ā-waha e tukuna ki te tangata kua tango disulfiram (Antabuse) i roto i ngā wiki e rua kua pahure ake nei, nā te mea kua pā ana te huinga ki ngā tauhohenga hinengaro. Ko tētahi inu noa te tūraru iti te taunakitanga. Ko te Antabuse me te metronidazole te mea kua tuhia.
E toru ngā rā i muri i tō pū whakamutunga te tau e pono ana
Ki te pātai koe kia hia te roa i muri i te metronidazole ka taea e koe te inu, ko te whakautu taunoa ko te 3 rā, tērā rānei 72 haora, i muri i tō pū rongoā whakamutunga, ko tēnei anō te mea e kii ana te tapanga a te FDA me MedlinePlus.
Rapua kia hia te roa i muri i te metronidazole ka taea e koe te inu, ka kite koe i te 24, 48, me te 72 haora e kii ana ngā momo tuhinga. Ko te nama 24-haora i ahu mai i te pharmacokinetics: he poto te haurua ora o te metronidazole, tata ki te waru haora, ā, ka whakawāteatia te nuinga i roto i te tata ki te rua rā. Ko ētahi aratohu ā-motu e whakamahi ana i te 48 haora. Ko te 3 rā o te tapanga he pātaka tiaki, kaua ko te taha tōrangitanga, ā, kāore he mea e huri ana i te pūtaiao i te haora 72.
E rua ngā whakarerekētanga e whai take ana. Ko ngā tāngata he mate ate ka āta whakawātea i te metronidazole, ā, me ui ki te kaitohutohu mō tētahi wā roa ake. Ā, ko te tinidazole-for-bv-when-it-is-used-instead-of-metronidazole" target="_blank" rel="noopener noreferrer">tinidazole ka mau i te tohutohu 3-rā taua.
Kua inu kē? Ko ngā tohu ngāwari ka mutu tonu māna
Ki te mea kua inu koe i te waina i te wā kei te tango koe i te metronidazole, ko te mea nui ka puta ko te kore noa o te aha. Ki te puta he aha, tēnā pea he whero o te kiri, he māuiui, he mamae te upoko, me te mamae o te puku, ka tīmata i roto i te kotahi, e rua rānei ngā haora, ā, ka iti haere me te kore he rongoā.
Kati te inu mō te toenga o te rongoā, inumia ngā wai, kai tētahi mea, ā, ārai te hiahia ki te whakamātau i te tuarua kia kite ai koe mehemea ko te tuatahi he mahi noa. Ko te nuinga o ngā tāngata kua inu waina mā te rongoā metronidazole ka pai anō te ahua i te ata.
Ko te mea kāore koe e tika ana kia mahia ko te mutu i te paturopi. Ko te mate kāore i rongoatia, ahakoa ko te bacterial vaginosis, trichomoniasis, tērā rānei he mate anaerobic, he raruraru nui ake i tētahi pō whero. Karangahia tō kaitohutohu i mua i te peke i tētahi pū rongoā. Ki te ngā tohu ka taka ki waho i te pikitia i runga ake nei, tirohia te rarangi whakatūpato whero i raro nei.
Kei te māuiui tonu koe, kāore hoki koe i te tino mōhio ki tāu e pa ana? Ko te $39 te utu mō te toro rongoā ohorere ā-ipurangi a August ka hono atu koe ki tētahi tākuta kua rēhitia i te US nāna e arotake ngā tohu, ā, ka whakahaere rongoā ina tika; ko te tākuta te whakatau i tērā, ehara ko te puka. Kāore he ataata e taea te aromatawai i te mamae o te uma, te ngaro o te māramatanga, tērā rānei te uaua ki te manawa, e hiahia ana ki te tiaki ohorere.
A, no te rapu awhina hauora, ā, a, no te rongoā, ehara i te waina, te raruraru
Karangahia te 911 tērā rānei haere ki te rūma ohorere ināianei mena:
- Te pupū o te mata, ngā ngutu, te arero, tērā rānei te korokoro, te hives whānui, tērā rānei te uaua ki te manawa
- Te mamae o te uma, te tere tērā rānei te ngākau kōpūkotekote, tērā rānei te ngaro o te māramatanga i muri i te inu
- Ngā hopu
- Te ruaki nui, te mau tonu rānei me ngā tohu o te maroke
Whakaritehia tētahi toro i roto i te wiki mena:
- He kōpō noa, he weriweri, tērā rānei te ngoikore o ngā ringaringa tērā rānei ngā waewae
- Te kōhuwhera nui, te mau tonu rānei
- Ētahi tohu tauhohenga ka mau tonu mō te ra kotahi
Ko aua tohu neurological he pānga taha o te metronidazole, ehara i te pānga ki te waina.
Kōrero ki tētahi tākuta i mua i te tīmatanga mena:
- Kua tango koe i te disulfiram (Antabuse) i roto i ngā wiki e rua kua pahure ake nei
- He mate ate tō koe e mōhiotia ana
- Ka nui tāu inu ia rā, kei reira te mutu i te wā kotahi ka mau te mate tangohanga
Te mutunga mō te metronidazole me te waina
E kii tonu ana te tapanga a te FDA kia kaua he waina i te wā o te rongoā me te 3 rā i muri mai; e kii ana ngā aratohu rongoā a te CDC kāore he take kia whakarērea. E mau tonu ana ēnei e rua, ā, kāore koe e whai ki te whakatau i waenganui i a rāua. I runga i te rongoā e whitu, e tekau rānei te roa, ko te tatari he iti te utu, ā, ka whakakore i te pātai katoa. Ko te tūraru e tino tika ana kia whakahaerea ko te disulfiram i tangohia i roto i ngā wiki e rua o te metronidazole, ehara ko tētahi anake karāhe waina. Ā, ahakoa tēhea tāu inu, whakaotia te paturopi.
Ngā Pātai Auau
Kei te pā te whakatūpato waina ki te gel metronidazole tērā rānei ngā whakauru ki roto i te pakitara?
Kāore i te nuinga. Ko te whakatūpato ā-waha kei reira nā te mea ka kawea te rongoā ki te tinana katoa e ngā papa, ā, ko te gel metronidazole ā-pakitara me te waina ka iti te pānga, nā te mea he iti rawa te mimiti ki roto i te tinana mai i te gel. Ko ētahi pukapuka a te kaihanga ka whakahoki tonu i te whakatūpato ā-waha ki ngā puka katoa, nō reira tirohia te hua motuhake i whakawhiwhia ki a koe, ā, pātai atu ki tō taote rongoā ki te kore koe e mārama.
Me wareware ahau ki te tapanga "karohia te waina" a tō taote rongoā inaianei kua kii te CDC kāore he take kia whakarērea?
Kao. Ka whakatakotohia e ngā taote rongoā te tapanga nā te mea e hiahiatia ana e te tapanga kua whakaaetia, ā, koira te mahi ngaio tika, ehara i te he hei whakakore. Ki te whai take ki a koe te aratohu mō te metronidazole me te waina, pātai atu ki a rātou tika atu i te whakatau mā te wahangu. Ka taea e rātou te whai whakaaro ki tō hauora ate, ngā rongoā kē atu, me te hua motuhake, e kore e taea e tētahi tuhinga whānui.
Ko te inu waina ka iti ake te whai hua o te metronidazole ki te whakawātea i te mate?
Kao. Kāore he taunakitanga e whakaatu ana ka whakaiti te waina i te kaha o te metronidazole ki te patu huakita tērā rānei ngā parar site. Ko te tūraru whai tikanga he kore tika: ki te kainga te waina ka ruaki koe i tētahi pū rongoā, ka moe koe i tētahi, tērā rānei ka ngaro te mahara ki te tikanga, ka iti ake te pono o te rongoā. Ko te whai i te tikanga whai tikanga he nui ake te take ki te hua i te mea tāu i inu tahi.
Kei te tatau ngā rongoā i te mangai, te rongoā mare, me ngā puna waina huna kē atu?
Mā te hangarau, āe. Ko te tohutohu a te tapanga e mau ana ki ngā hua kei roto te waina tērā rānei te propylene glycol, ehara ko ngā inu anake. I te mahi, ko te rongoā i te mangai e horoia ana, ka tautunu he iti rawa te whakawhiwhi, ko te rongoā mare e horomia ana kia maha ngā wā i te rangi he mea nui ake. Kei te wātea ngā putanga kāore he waina o ēnei e rua mena ka pai ake koe ki te kore e whakaaro ki tērā.
Ka taea e te metronidazole te mahi kia kaha ake te painga o tētahi anake inu i te tikanga?
Tērā pea. Nā te mea ka āta whakawātea te waina atu i tō tikanga, ka kaha ake te painga o tētahi inu, tērā rānei ka roa ake i te mea i tatarihia. Ko te hua whai tikanga he ngāwari: kaua e whakaaro ka pā tō te manawa noa, ina koa ki te taraiwa tērā rānei tetahi mea e pā ana ki te iti ake te whara i te mea i whakaaroa e koe.
Whakakāhoretanga: Ko tēnei tuhinga mō te mōhiohio anake, ā, ehara i te tohutohu hauora. Kōrero tonu ki tētahi kaiwhakarato hauora whai tohu mō ngā whakatau arohaehae me te rongoā. Ki te wheako koe i tētahi ohorere hauora, karangahia te 911 tērā rānei haere ki te rūma ohorere tata tonu.
