He aha te Reslizumab: Ngā Whakamahinga, te Inenga, ngā Pānga taha me ētahi atu

He rongoā motuhake te Reslizumab i hangaia hei āwhina i te hunga e mate ana i te huangō nui, kāore e pai te whakautu ki ngā rongoā paerewa. He rongoā whāinga tēnei e mahi ana mā te aukati i tētahi pūmua motuhake i tō pūnaha ārai mate e kīia nei ko te interleukin-5, he mea nui tōna mahi ki te whakaoho i ngā whakaeke huangō.

No tētahi rōpū rongoā tēnei rongoā e kīia nei ko ngā paturopi monoclonal. Whakaarohia he taputapu tika e āwhina ana ki te whakamārie i te whakautu ārai mate kaha rawa atu e uaua ai te whakahaere i te huangō nui ki ngā whakakōpiko me ngā pire auau.

He aha te Reslizumab e whakamahia ana mō?

Kua whakaaetia te Reslizumab mō te rongoā i te huangō eosinophilic nui i roto i ngā pakeke me ngā tamariki 18 tau me te pakeke ake. Ko te huangō eosinophilic tētahi momo motuhake o te huangō nui e kaha rawa ana ētahi pūtau toto mā e kīia nei ko ngā eosinophils, ā, ka pā mai te mumura i roto i ō rātou ara rererangi.

Ka whakaaro tō tākuta ki tēnei rongoā i te wā e kore e pai te whakahaere i tō huangō ahakoa te whakamahi i ngā corticosteroids i te horopeta nui me tētahi atu rongoā whakahaere. Kei te rāhui mō ngā take kāore i whai hua ngā rongoā tuku iho ki te whakaiti i ngā tohumate pēnei i te whakaeke huangō auau, te uaua ki te hā, te whakaheke rānei i te mahi o te pūkahukahu.

He tino whai hua te rongoā mō te hunga e pā ana ki te pūhihi huangō auau e hiahia ana ki ngā corticosteroids waha, ki ngā haerenga rānei ki te ruma ohorere. Ka taea e ia te whakaiti i te maha o ngā pūhihi nui me te whakapai ake i tō kounga oranga.

Me pēhea te mahi a te Reslizumab?

E mahi ana te Reslizumab mā te whāinga me te aukati i te interleukin-5, tētahi pūmua e tohu ana i tō tinana ki te whakaputa me te whakahohe i ngā eosinophils. Ko ēnei eosinophils he pūtau toto mā, i te wā e kaha rawa ana, ka pā mai te mumura nui i roto i ō rātou ara rererangi, ā, ka nui ake te kino o ngā tohumate huangō.

Na te aukati i tēnei ara motuhake, ka āwhina a reslizumab ki te whakaiti i te maha o ngā eosinophils i roto i tō toto me ō pūkahukahu. Ko te mutunga mai, he iti ake te mumura o te ara rererangi, he iti ake ngā whakaeke huango, me te pai ake o te manawa i te roanga o te wā.

E kiia ana he rongoā kaha tēnei e mahi rerekē ana i ngā rongoā huango tuku iho. Ahakoa e mahi tika ana ngā inhalers i roto i ō pūkahukahu, ka mahi a reslizumab puta noa i tō pūnaha ārai mate ki te whakatika i te take o te huango eosinophilic.

Me pēhea taku tango i te Reslizumab?

Ka tukuna a Reslizumab hei whakauru i roto i te uaua, ko te tikanga ka tukuna tika ki roto i tō toto mā roto i te uaua i tō ringa. Ka whiwhi koe i tēnei rongoā i te tari o tō tākuta, i te hōhipera, i te whare whakauru rānei - kaua rawa i te kāinga.

Ko te tikanga ka tukuna te rongoā ia whā wiki, ā, ka roa te whakauru i te 20 ki te 50 meneti hei whakaoti. Ka mātakitaki tata tō rōpū hauora i a koe i te wā o te whakauru me muri i ia whakauru kia mātakitaki i ngā tauhohenga.

I mua i ia rongoā, kāore koe e hiahia ki te whai i ngā here kai motuhake. Heoi, he mea nui kia noho pai te wai me te kai noa iho ki te kore ō tākuta e tohutohu kē. Me haere tonu koe ki te tango i ō rongoā huango i te mea kua whakaritea, ahakoa e whiwhi ana koe i te reslizumab.

Ka tātai tō tākuta i tō horopeta tika i runga i tō taumaha tinana, te tikanga 3 milligrams mō ia kirokaramu o te taumaha tinana. Ko tēnei horopeta whaiaro e āwhina ana ki te whakarite kia whiwhi koe i te nui tika mō ō hiahia motuhake.

Kia Pēhea te Roa o taku Tango i te Reslizumab?

He rerekē te roanga o te rongoā reslizumab mai i te tangata ki te tangata, i runga i te pai o tō urupare ki te rongoā me tō mana huango whānui. He maha ngā tāngata e haere tonu ana i te rongoā mō te maha o ngā marama ki ngā tau kia mau tonu ngā painga.

Ka arotakehia e tō tākuta tō ahunga whakamua i muri i ngā marama tuatahi o te rongoā. Ka titiro rātou ki ngā āhuatanga pēnei i te auau o ō whakaeke huango, mehemea e hiahia ana koe i ngā steroid waha iti iho, me ngā whakapainga i roto i ō whakamātautau mahi pūkahukahu.

Ka kite ētahi tāngata i ngā whakapainga i roto i ngā rongoā tuatahi, engari ka hiahiatia e ētahi atu ētahi marama kia pōtaea ai ngā painga katoa. Ka mahi tō rōpū hauora ki a koe ki te whakatau i te roa o te rongoā e tika ana i runga i tō urupare takitahi me ngā pānga taha ka pā ki a koe.

He aha ngā Pānga Taha o Reslizumab?

Pērā i ngā rongoā katoa, ka taea e reslizumab te pānga taha, ahakoa he maha ngā tāngata e pai ana ki te tango. Mā te māramatanga ki ngā mea e tūmanakohia ana ka āwhina koe ki te whai wāhi atu, me te mōhio ki te wā ki te whakapā atu ki tō rōpū hauora.

Ko ngā pānga taha tino noa he ngawari, he whakahaere hoki. Ko ēnei urupare ka puta i te wā, i muri tata rānei i tō rongoā, ā, he maha tonu ka pai ake i te wā e whakatika ana tō tinana ki te rongoā:

• Te mamae o te upoko me te ngenge
• Te mamae o te uaua, o te hononga rānei
• Te riri o te korokoro, te korokoro mamae rānei
• Te pūhihi o te ihu
• Te whakapairuaki, te kore rānei o te hāneanea o te puku
• Te whanoke
• Ngā urupare kiri i te wāhi werohanga

Ko te nuinga o ēnei pānga taha noa he wā poto, ka ngaro noa iho i roto i te rā, e rua rānei i muri i tō rongoā.

Ko ngā pānga taha nui ake he iti noa iho, engari e hiahia ana kia aro mai te rongoā tonu. Kei roto i ēnei ko ngā urupare pānga nui i te wā, i muri rānei i te rongoā, koinei te take ka āta aroturukihia koe i te wā o te rongoā:

• Ngā urupare pānga nui me ngā tohu pēnei i te uaua ki te manawa, te pūhihi o te mata, o te korokoro rānei, te pupuhi nui rānei
• Te heke nui o te pēhanga toto
• Te mamae o te uma, te tere rānei o te ngākau
• Te whanoke nui, te ngaro rānei o te mōhiotanga
• Ngā mate rerekē nā te pānga pea ki tō pūnaha ārai mate

He tino onge engari he kino nga paanga taha ka uru pea ki te piki ake o te tupono ki etahi momo mate pukupuku, ahakoa he iti rawa tenei tupono. Ka matapakihia e to taakuta enei mea kaore i te kitea ki a koe, ka whakataurite i a raatau ki nga painga o te maimoatanga mo to huango kino.

Ko wai e kore e tango Reslizumab?

Kaore a Reslizumab e tika ana mo te katoa, a ka ata tirotirohia e to taakuta mena he tika tenei rongoa mo to ahuatanga motuhake. He maha nga mea ka kore e tika tenei maimoatanga, me whakatupato motuhake ranei.

Kaua koe e tango reslizumab mena i pa ki a koe he mate pāwera nui ki a ia i mua. I tua atu, kaore tenei rongoa i whakaaetia mo nga tamariki kei raro iho i te 18 tau, na te mea kaore ano i whakapumautia te haumaru me te whai huatanga i roto i nga turoro iti.

Ka tino tupato to taakuta ki te whakahau reslizumab mena kei a koe etahi ahuatanga ka piki ake pea to tupono ki nga raruraru:

• Nga mate kaha o naianei, he hitori ranei o nga mate e hoki ana
• Nga mate pirinoa, ina koa nga mate helminth
• He punaha aukati i te mate i ahu mai i etahi atu rongoa, i etahi ahuatanga ranei
• Hitori o te mate pukupuku
• Te haputanga, te whakangote u ranei
• Te mate ate, te mate whatukuhu ranei

Mena kei a koe etahi o enei ahuatanga, ehara i te mea kaore e taea e koe te whakamahi reslizumab, engari me ata whakataurite e to taakuta nga tupono me nga painga, a tera pea ka hiahia ki etahi atu aroturuki.

Nga Ingoa Waitohu Reslizumab

Ka hokona a Reslizumab i raro i te ingoa waitohu Cinqair i Amerika me etahi atu whenua. Koinei te ingoa waitohu tuatahi ka tutaki koe i te wa e korero ana koe mo tenei rongoa ki to roopu hauora, ki te kai rongoa ranei.

I ētahi rohe, ka kitea pea e koe i raro i ngā ingoa waitohu rerekē, engari ko te whakauru kaha tonu te mea kotahi. Me mōhio tonu ki tō tākuta kia mōhio ai kei te whiwhi koe i te rongoā tika, ina koa kei te haere koe, kei te whiwhi rongoā rānei i roto i ngā pūnaha hauora rerekē.

Ngā Kōwhiringa kē mō Reslizumab

He maha atu ngā rongoā e mahi ana i te ara rite ki te reslizumab mō te huangō eosinophilic nui, e hoatu ana ki a koe me tō tākuta ngā kōwhiringa ki te kimi i te rongoā pai rawa atu mō ō hiahia motuhake. Ko ēnei kōwhiringa kē he paturopi monoclonal hoki e whai ana i ngā ara rerekē i roto i te pūnaha ārai mate.

Ko Mepolizumab (Nucala) tētahi atu rongoā e whai ana i te interleukin-5, he rite ki te reslizumab. Ka hoatu i te āhua o te werohanga i raro i te kiri ia whā wiki, e kitea ana e ētahi tāngata he pai ake i ngā whakaurunga i roto i te uaua.

Ko Benralizumab (Fasenra) e whai ana i te kaiwhiwhi interleukin-5, ā, ka hoatu hoki i te āhua o te werohanga i raro i te kiri. E pai ana ētahi tāngata ki tēnei kōwhiringa nā te mea ka whakahaerehia ia waru wiki i muri i ngā horopeta uta tuatahi.

Mō ngā tāngata e pā ana ki te huangō pānga, ko omalizumab (Xolair) e whai ana i ngā paturopi IgE, ā, he pai ake pea te kōwhiringa. Ko Dupilumab (Dupixent) tētahi atu kōwhiringa e whai ana i ngā ara interleukin-4 me interleukin-13.

Ka āwhina tō tākuta ki te whakatau ko tēhea kōwhiringa kē te mea pai rawa atu i runga i tō momo huangō motuhake, ō taumata eosinophil, me ētahi atu āhuatanga pēnei i tō hiahia mō te auau werohanga me te wāhi.

He Pai Ake Anei a Reslizumab i te Mepolizumab?

He rongoā tino whai hua a Reslizumab me te mepolizumab mō te huangō eosinophilic nui, ā, kāore tētahi i te tino

Ka tukuna a Reslizumab hei whakauru i roto i te uaua ia wha wiki, i te mea ka tukuna a mepolizumab hei werohanga i raro i te kiri ka taea e koe te ako ki te tuku i a koe i te kainga. He pai ki etahi tangata te watea o te werohanga-a-tangata, engari he pai ake etahi ki nga whakaurunga e tirotirohia ana.

E rua nga rongoa e whai ana i te ara kotahi i roto i to punaha aukati me te whakaatu i te whai huatanga rite i roto i nga whakamatautau haumanu. E rua e tino whakaiti ana i nga whakaroanga o te huango me te hiahia mo nga corticosteroids waha i roto i nga tangata e mate ana i te huango eosinophilic nui.

Ko te whakatau i te nuinga o te wa ka whakawhirinaki ki nga mea penei i to taumata whakamarie ki nga momo werohanga rereke, to waatea mo nga haerenga ki te whare haumanu, me te pehea e urupare ai to tinana ki ia rongoa. Ka whakaarohia e to taakuta enei mea me to hitori rongoa hei awhina i a koe ki te whiriwhiri pai.

Nga Pātai e Pātai pinepine ana mo Reslizumab

He Haumaru a Reslizumab mo te hunga e mate ana i te ngakau?

Ka taea te whakamahi i te Reslizumab i roto i te hunga e mate ana i te ngakau, engari me mahi tahi to tohunga ngakau me te tohunga pukahukahu ki te aro turuki i a koe. Ko te rongoa ake nei karekau e pa tika ki te mahi ngakau, engari ko te tukanga whakauru e hiahia ana kia tino aro turuki i o tohu nui.

Mena he mate ngakau koe, ka aro nui to roopu hauora ki to toto me te tere o te ngakau i te wa o te whakaurunga. Ka taea hoki e ratou te whakatika i te reeti whakauru kia pai ai to whakamarie me to haumaru puta noa i te maimoatanga.

Me aha ahau ki te ngaro ohorere ahau i te horopeta o Reslizumab?

Mena ka ngaro koe i to whakaurunga reslizumab kua whakaritea, whakapā atu ki to kaiwhakarato hauora i te wa e taea ai ki te whakarite ano. Kaua e ngana ki te takirua i nga horopeta, ki te utu ranei mo te maimoatanga kua ngaro i a koe ano.

Ka whakarite anō tō tākuta i tō horopeta kua ngaro i te wā e taea ai, ā, ka haere tonu i tō hōtaka whā-wiki mai i taua wā. Ko te ngaro i tētahi horopeta e kore e puta he raruraru tonu, engari he mea nui kia mau tonu te rite mō ngā hua pai.

Me pēhea te mahi mēnā ka pā mai he pānga mate pāwera i te wā o te rongoā?

Mēnā ka pā mai ngā tohu o te pānga mate pāwera i te wā o tō rongoā reslizumab, whakamōhio tonu ki tō rōpū hauora. Ko ngā tohu hei mātakitaki ko te uaua ki te hā, te pūhi o tō mata, o tō korokoro rānei, te pāngia nui, te ngoikore rānei.

Kua pai te whakarite o tō pokapū rongoā ki te whakahaere i ngā pānga mate pāwera, ā, ka wātea tonu ngā rongoā ohorere. Ka mutu tonu te rongoā, ā, ka whakawhiwhia te rongoā tika, arā, ko ngā antihistamines, corticosteroids, epinephrine rānei mēnā e hiahiatia ana.

Āhea e taea ai e au te whakamutu i te tango i te Reslizumab?

Ko te whakatau ki te whakamutu i te reslizumab me mahi tonu i te taha o tō tākuta, kaua rawa e mahi anake. Ka arotake tonu tō rōpū hauora i tō urupare ki te rongoā, ā, ka āwhina ki te whakatau i te wā tika hei whakaaro ki te whakamutu.

Ka taea e ētahi tāngata te whakamutu i muri i te pai o te whakahaere i tō rātou huangō mō te wā roa, i te wā e hiahia ana ētahi atu ki te haere tonu i te rongoā mō te wā roa. Ka whakaaro tō tākuta ki ngā āhuatanga pēnei i tō whakahaere tohu, te mahi o te pūkahukahu, me te kaha ki te whakaiti i ētahi atu rongoā huangō i te wā e whakatau ana i tēnei whakatau.

Ka taea e au te whiwhi kano ārai mate i te wā e tango ana i te Reslizumab?

Ka taea e koe te whiwhi i te nuinga o ngā kano ārai mate i te wā e tango ana i te reslizumab, engari he mea nui kia kōrerohia tēnei ki tō kaiwhakarato hauora i mua i te whiwhi i ngā kano ārai mate. Kāore pea i te tūtohutia ngā kano ārai mate ora, i te wā e haumaru ana ngā kano ārai mate kore mahi.

Ka tohutohu pea tō tākuta kia whakarite i te wā o āu werohanga i waenga i ngā whakaurunga reslizumab kia whai hua ai. Me mōhio anō rātou kāore koe e pā ana ki ngā mate e kaha ana i mua i te whiwhinga werohanga, nā te mea ka pā tēnei ki tō urupare ārai mate.