Maastootoosisis Siistemaatik

Sisteemik mastositoosis (mas-to-sy-TOE-sis) dhukkuba hin barbaachifne dha, inni mast seelota hedduu qaama keessatti walitti qabachuu dhiheessu. Mast seelota gosa dhiiga adii dha. Mast seelotonni qaama keessatti jiran walitti qabaman keessa jiraatu. Mast seelotonni hojii sirna ittisa qaamaa sirriitti hojjechuuf gargaaran, akkasumas dhukkuba irraa ittisuuf gargaaru.

Yommuu sisteemik mastositoosis qabaatte, mast seelota hedduun gara balbala, lafee summii, qaama dijeetiiv, ykn qaama qaama biraa keessa walitti qabamu. Yommuu kaka'an, mast seelotonni kun wantoota mallattoofi beekkumsa akka ri'aa'aa fakkaatu, yeroo tokko tokko immoo walitti bu'iinsa cimaa qaama miidhuu danda'u baasan. Kaka'umsa baay'een alkaholii, nyaata hawwaa, dhiibbaa bineensa, ykn qoricha tokko tokko dabalata.

Mallattoofiifi mallattoosa mastocytosis haalaa guutummaa qaamaa, hedduun seluloota mast kan miidhagdu qaamaa irratti hundaa'a. Seluloota mast hedduun gara balbala, tiree, dhibee, lafee ykn gara gadameessaatti walitti qabamuun ni danda'a. Baay'ee hin taane, qaamota biroo kan akka sammuu, onnee ykn sammuutti kan miidhamu ta'a. Mallattoofiifi mallattoosa mastocytosis haalaa guutummaa qaamaa kanneen armaan gadii of keessaa qabaachuu danda'a: Bifa jijjiirama, gidiraa ykn qoricha Dhukkubbii gadameessa, garaa dheebbaa, dhibee ykn qara Anemia ykn rakkoo dhiiga Dhukkubbii lafee fi firiif Tiree, dhibee ykn qooda limfi guddatan Dhiibbaa, jijjiirama yaada ykn rakkoo xiyyeeffannaa Seluloota mast wantoota walitti qabamanii fi mallattoosa uumaan ni kaka'amu. Namoonni kaka'umsa adda addaa qabu, garuu kanneen baay'inaan argaman armaan gadii of keessaa qabu: Alkool Balbala miidhaa Nyaata ba'aa Sochii Qoricha insekta Qorichoota tokko tokko Yommuu doktera arguu qabdu Yoo rakkoo bifa jijjiiramaa ykn qoricha qabaattu, ykn yoo yaaddoo mallattoofiifi mallattoosa armaan olitti tarreessan irratti qabaattu, doktera keessan waliin haasawaa.

Dhibeen mastocytosis of systemic hedduun jijjiirama (mutation) utuu hin yaadamne keessatti uumamuu KIT gene irratti mul'ata. Waa'ee KIT gene kanaa dogongora kanaa dhaaluu irraa kan argamu miti. Seelota mast hedduun oomishamaa fi qaamaa fi qaama qaama keessatti walitti qabamanii, maatiin akka histamine, leukotrienes fi cytokines kan walitti bu'iinsa fi mallattoowwan uumaan baasan.

Rakkoolee mastocytosis haala waliigalaa irraa dhufan kana keessa jiraatu:

• Deebii anaphylaxis. Kun deebii aleejirgii cimaa yoo ta'u, mallattoolee fi malaammaltoonni akka garaa saffisaan rukutu, gad lafaan kufuu, yaada dhabuu fi shookiidha. Yoo deebii aleejirgii cimaa qabaatte, injeeshinii epinephrine barbaachisa ta'a.
• Dhukkuba dhiiga. Kun aniiimiyaa fi dhiigni gaariitti hin guutamne dabalata.
• Dhukkubbii ulser peptik. Irriitaan garaa yeroo dheeraa ulserii fi dhiigni sirna diijeshiinii keessatti ba'uu geessisa.
• Gaaddisa lafee hir'ina. Mastocytosis haala waliigalaa lafee fi hirriira lafee keessatti miidhaa geessiisuudhaan, rakkoolee lafee, akka osteoporosisitti, keessa galuunsaa.
• Hiddiin qaamaa hin hojjetne. Seelota mast qaama keessatti walitti guutummaan, madda qal'inaa fi miidhaa qaamaa geessisa.

To diagnose systemic mastocytosis, your doctor will likely start by reviewing your symptoms and discussing your medical history, including medications you've taken. He or she can then order tests that look for high levels of mast cells or the substances they release. Evaluation of organs affected by the condition also may be done. Tests may include: Blood or urine tests Bone marrow biopsy Skin biopsy Imaging tests such as an X-ray, ultrasound, bone scan and CT scan Biopsy of organs affected by the disease, such as the liver Genetic testing Types of systemic mastocytosis The five main types of systemic mastocytosis include: Indolent systemic mastocytosis. This is the most common type and usually doesn't include organ dysfunction. Skin symptoms are common, but other organs may be affected, and the disease may worsen slowly over time. Smoldering systemic mastocytosis. This type is associated with more-significant symptoms and may include organ dysfunction and worsening disease over time. Systemic mastocytosis with another blood or bone marrow disorder. This severe type develops rapidly and is often associated with organ dysfunction and damage. Aggressive systemic mastocytosis. This rare type is more severe, with significant symptoms, and is usually associated with progressive organ dysfunction and damage. Mast cell leukemia. This is an extremely rare and aggressive form of systemic mastocytosis. Systemic mastocytosis most commonly occurs in adults. Another type of mastocytosis, cutaneous mastocytosis, typically occurs in children and usually affects only the skin. It generally doesn't progress to systemic mastocytosis. Care at Mayo Clinic Our caring team of Mayo Clinic experts can help you with your systemic mastocytosis-related health concerns Start Here

Wallagga, kan sirna maastootoosisii fi qaama qaama qaama miidhame irratti hundaa'a. Wallaggaas, sirreeffama mallattoowwan, dhibee itti fayyadamuu fi hordoffii yeroo hunda dabalata. Dhaabbii kaka'umsa Jireenya keessatti kaka'umsa seluloota maastii keessan kaka'su, akka nyaata, qoricha ykn dhuka'aa inseektaa, adda baasuun fi itti fufuun, mallattoowwan sirna maastootoosisii keessan to'achuuf gargaara. Qorichoota Doktarri keessan qorichoota kanaaf yaada kennuu danda'a: Mallattoowwan itti fayyadamuu, fakkeenyaaf, antihistamiinoota Asidii garaa fi dhiphinna sirna diijestii keessan hir'isu Dhiibbaa maatiriyaa seluloota maastii keessan gadhiisan irratti tarkaanfii fudhachuu, fakkeenyaaf kortikosteroiidoota Jini KIT dhaabuu seluloota maastii oomisha isaa hir'isu Ogeessi fayyaa tokko, yeroo seluloota maastii keessan kaka'an deebii aalirjiitii cimaa qabaattanitti, injekshinii epinefiriinii of kennuu akkamitti akka godhatan barsiisuu danda'a. Keemootiraapii Sirna maastootoosisii cimaa, sirna maastootoosisii dhibee dhiiga biraa wajjin walitti hidhamee ykn lukiiimiyaa selula maastii qabaattanii yoo ta'e, lakkoofsa seluloota maastii hir'isuuf qorichoota keemootiraapii itti fayyadamuu ni dandeessu. Guutuun selulaa Namoota sirna maastootoosisii sadarkaa ol'aanaa, lukiiimiyaa selula maastii jedhamu qabanif, guutuun selulaa filatamuu danda'a. Hordoffii yeroo hunda Doktarri keessan haala haala keessan hordofuuf, qormaata dhiiga fi sharafa fayyadama. Mallattoowwan mudatanitti, dhiiga fi sharafa walitti qabuuf meeshaalee mana keessatti fayyadamuu dandeessu, kunis doktarri keessan sirna maastootoosisii qaama keessan akkamitti akka miidhu hubachuuf gargaara. Lakkoofsa gaaddisa lafaa yeroo hunda, rakkoolee akka oostiyooporoosisiiitti hordofuu dandeessa.

Dhibee jiraataa akka mastocytosis jedhamu kun nama dhiphisaa fi nama dadhabsiisa. Yaadawwan kunneen yaadii: Dhibicha baradhu. Waan dandeessutti hundumaa mastocytosis jedhamuu baradhu. Sana booda filannaa gaarii gochuu fi ofii keessanif abukaatoo ta'uu dandeessa. Miseensa maatii fi hiriyyootni keessan haala kana, kunuunsa barbaachisaa fi of eeggannoo barbaachisu hubatanii akka isiniif ta'an godhaa. Gareen ogeessota amanamaa argadhaa. Murtee barbaachisaa kunuunsa irratti murteessuu qabda. Giddu-galeen fayyaa garee ogeessotaa qaban odeeffannoo mastocytosis, gorsa fi deeggarsa, akkasumas kunuunsa akka isiniif ta'an isiniif kennuu danda'u. Deeggarsa biraa barbaadaa. Namoonni rakkinoota walfakkaata qaban waliin dubbachuun odeeffannoo fi deeggarsa miiraa isiniif kennuu danda'a. Doktarri keessan humnaalee fi garee deeggarsa hawaasa keessaniitti jiran gaafadhaa. Garee deeggarsa keessatti yoo of hin eegganne, dokterri keessan namni mastocytosis qabaatee walitti dhiheessuu danda'a. Yookiin garee yookiin deeggarsa dhuunfaa interneetii irratti argachuu dandeessa. Gargaarsa maatii fi hiriyyootarraa gaafadhaa. Yeroo barbaachise gargaarsa maatii fi hiriyyootarraa gaafadhaa yookiin fudhadhaa. Yaadaa fi hojii keessaniif yeroo kennuu. Gorsa ogeessa fayyaa sammuu waliin ta'uun walitti qabamuu fi walitti fuudhuu keessatti gargaara.