Maal Faaktara Koogulaashinii IX (Reekombinaantii, Gilaayikoopeegilaayiteed)? Mallattoolee, Sababoota, & Wal'aansa Manaa

Faaktarri Koogulaashinii IX (ree-kombinaantii, gilaayikoopeegilaayiteed) qoricha addaa kan dhiigni keessan akka sirritti itti hidhamuuf kan gargaaru yoo heemofiliyaa B qabaattanidha. Kunis pirootiinii itti hidhama uumamaa kan laaboraatooriidhaan hojjetame yoo ta'u, dandeettii qaamni keessan dhiiga dhaabuu akka deebisu gargaara. Qorichi kun IV karaa kennamaa, pirootiinii Faaktara IX kan dhabame ykn kan hin hojjanne qaamni keessan itti hidhama dhiigaa uumuuf barbaadu bakka buusa.

Maal Faaktara Koogulaashinii IX (Reekombinaantii, Gilaayikoopeegilaayiteed)?

Qorichi kun pirootiinii barbaachisaa dhiigni keessan akka itti hidhamuuf barbaadu, Faaktara IX kan namaan hojjetameedha. Yoo heemofiliyaa B qabaattan, qaamni keessan pirootiinii kana gahaa hin oomishu ykn kan sirritti hin hojjanne oomisha. Kutaan "ree-kombinaantii" jedhu akkaataa teeknooloojii baayoo-teeknooloojiidhaan laaboraatooriitti uumamuu isaa kan agarsiisudha malee dhiiga namaa irraa kan argamuu miti.

Kutaan "gilaayikoopeegilaayiteed" jedhu uffata addaa qoricha irratti dabalamu kan dhiiga keessatti yeroo dheeraaf akka turu gargaaru kan agarsiisudha. Uffanni kun gaachana eegumsaa fakkaata, qorichi yeroo dheeraaf akka hojjetu taasisa, akkasumas baay'ina sirna injikshinii akka hir'isu gargaara. Kunis qorichaaf humna yeroo dheeraaf turu kennuu fakkaata.

Wal'aansi Faaktara Koogulaashinii IX akkamitti ni dhaga'ama?

Namoonni hedduun sirni IV kennuu salphaa fi mijataa akka ta'e ni hubatu. Teessuma keessa taa'aa qorichi dafee dafee daqiiqaa 15 hanga 30 gidduutti damara keessanitti akka yaa'u gootu. Muuxannoon kun akkaataa IV wal'aansa fayyaa biroo argachuutti fakkaata, jalqaba irratti cirracha cirracha xiqqaa qaba.

Yeroo itti fayyadamni qorichaa gaggeeffamu, wanti tokkoyyuu akka hin dhagahamne gochuu dandeessa, kunis waanuma baramaa dha. Namoonni tokko tokko yeroo qorichi dhiiga isaanii keessa seenu miira qabbanaa'aa xiqqaa ni dhaga'u. Erga yaalamee booda, namoonni baay'een dhiigni isaanii akka gaariitti walitti qabamuu danda'a jedhanii amansiifamuu isaanii ni himu, keessumaa yoo dhiigni itti yaa'aa ture.

Bu'aawwan gama tokkoon dhufan, yeroo dhufanitti, yeroo baay'ee salphaa dha, mataa dhukkubbii, giddigisaa, ykn quufuu xiqqaa dabalata. Miirri kunniin yeroo baay'ee erga itti fayyadamni qorichaa xumuramee booda saffisaan ni darbu. Gareen fayyaa keessanii yeroo yaala keessatti fi erga yaalamee booda akka isin mijattu mirkaneessuuf isin hordofa.

Maaliif yaalii Coagulation Factor IX barbaachisa?

Sababni guddaan qoricha kana barbaachisuu dandeessan hemophilia B, dhukkuba dhiigaa kan geneetikii kan akka dhiigni keessan itti walitti qabamu kan miidhu dha. Haalli kun kan uumamu yeroo geneenota jijjiramanii kan qaamni keessan pirootinii Factor IX kan normal ta'e akka hin hojjanne isin dhaaltanidha. Factor IX hojii irra jiru gahaa hin ta'u yoo ta'e, dhiigni keessan akka gaariitti walitti qabamuu hin danda'u, kunis dhiigni akka dheeraatti yaa'u geessa.

Hemophilia B maatii keessatti darba, yeroo baay'ee haadholii irraa gara daa'imman isaaniitti. Haalli kun kiroomoza X irratti dhiibbaa waan qabuuf, dhiirota irratti baay'inaan kan argamu ta'us, dubartoonnis baattuu ta'uu danda'u, ykn yeroo muraasa keessatti, haala kana mataan isaanii qabaachuu danda'u. Isin haala kana waliin dhalattan, garuu mallattoonni dhiigni yaa'uu daa'imummaa booda ykn waggoota guddaa keessatti hin mul'atu.

Yeroo tokko tokko, namoonni sababa dhukkuboota dhiigaa argaman irraa kan ka'e bakka bu'aa Factor IX barbaachisu. Kunis qorichoota tokko tokko, haala oto-immune, ykn dhukkuba tiruu kan qaama keessan humna walitti qabamuu uumuu danda'u irratti dhiibbaa qabu irraa kan ka'e ta'uu danda'a. Doktarri keessan sababa bu'uuraa qorannoo dhiigaa fi seenaa fayyaa fayyadamuun murteessa.

Hanqina Factor IX mallattoo ykn mallattoo maaliiti?

Hanqina Factor IX keessatti, dhibee hemophilia B, kan dhibee Kiristimaas jedhamuun beekamu, mallattoo guddaadha. Haalli geneetikii kun qaamni kee proteeniin Factor IX hojii hin qabne xiqqaa ykn hin oomishu jechuudha. Hamaatni hemophilia keetii hammam Factor IX qaamni kee hojii irra oolchu irratti hundaa'a.

Hemophilia B hamaa yeroo hojii Factor IX normalii %1 gadii qabaattan ni mul'ata. Namoonni bifa hamaa qaban yeroo baay'ee walnyaatinsa qaama keessaa, maashaalee, fi qaamota keessaa keessatti argamu ni muudatu. Hemophilia B giddu-galeessaa hojii normalii %1-5 kan qabu yoo ta'u, yeroo baay'ee miidhama xiqqaa ykn adeemsa wal'aansaa booda dhiigni akka yaa'u godha.

Hemophilia B salphaan jechuun hojii Factor IX normalii %5-40 qabaachuu jechuudha. Yeroo marsaa yaala, hojii ilkaanii, ykn miidhama guddaa keessatti dhiigni baay'ee yoo yaa'u, haala kana akka qabdu hin hubattu ta'a. Namoonni hemophilia B salphaa qaban tokko tokko waggoota hedduuf osoo hin qoratamini turu.

Yeroo muraasa keessatti, hanqinni Factor IX umurii booda sababa haalota oto-immune, kanneen keessatti sirni ittisa qaamaa dogoggoraan wantoota dhiiga ittisaniif haleellaa godhuun dhufuu danda'a. Dhibeen tiruu hamaas oomisha Factor IX ni hir'isa, sababiin isaas tiruun kee proteeniin dhiiga ittisanii baay'ee oomisha.

Hanqinni Factor IX ofumaa ni badaa?

Garuu, hanqinni Factor IX geneetikii kan hemophilia B irraa dhufu, haala jireenyaa guutuu kan ofumaa hin fayyineedha. Sababiin isaas, jijjirama jiinii irraa kan ka'e, qaamni kee jireenya kee guutuu keessatti proteeniin Factor IX normalii oomishuuf rakkina qabaachuu itti fufa. Garuu, kun yaala fi to'annaa sirrii ta'een jireenya guutuu fi ho'aa jiraachuu hin dandeessu jechuu miti.

Oduun gammachiisaan, yaalli bakka bu'aa Factor IX haala kee to'achuu danda'a. Yaalli yeroo hundaa dhufuun walnyaatinsa dhiigaa ni ittisa, akkasumas hojiiwwan normalii baay'ee irratti hirmaachuu siif hayyama. Namoonni hemophilia B qaban baay'een, kunuunsa fayyaa sirrii ta'een jireenya normalii guutuu jiraatu.

Yoo hanqina Factor IX kee kan dhufan dhibeewwan biroo kan akka dhukkuba tiruufi dhukkuboota ofii of irratti dhufan ta'e, dhukkuba hundee irratti yaaluun sadarkaa Factor IX kee fooyyessuu danda'a. Doktarri kee sababoota kanneen furuuf si waliin ni hojjata yoo barbaachisaa ta'e bakka Factor IX buusuun ni kenna.

Akkaataa hanqina Factor IX mana keessatti itti yaalamu danda'amu

Hanqina Factor IX qoricha manaatiin yaaluu kan hin dandeenye ta'us, leenjii yaala fayyaa sirrii ta'een mana keessatti haala kee to'achuu barachuu dandeessa. Namoonni baay'een hemophilia B qaban ofii isaaniitiif Factor IX mana keessatti of kennuu baratu, kunis yeroo barbaachisaa ta'etti jijjirama guddaa fi yaala saffisaa ni kenna.

Gareen yaala fayyaa kee akkaataa qoricha kana qopheessuufi nageenyaan kennuu siif barsiisu ykn miseensota maatii keetii barsiisa. Adeemsichi kun qoricha sirnaan kuusuu, teeknikiin qulqullinaa walitti makuufi of kennuuf fayyadamuufi yeroo yaalli barbaachisu hubachuu ni dabalata. Yaalli mana keessaa keessattuu yeroo walitti bu'iinsi dhiigaa xiqqaan saffisaan to'achuuf baay'ee barbaachisaa ta'uu danda'a.

Naannoo mana nageenyaa uumuunis barbaachisaa dha. Kunis yeroo hojiiwwan gaggeessitanitti meeshaalee eegumsaa fayyadamuu, daandiiwwan salphaatti itti deemamuufi kuufamuu ittisuuf qopheessuu, odeeffannoo bilbilaa hatattamaa qopheessuu jechuudha. Doktarri kee akkaataa dhiigaa kee fi jireenya kee irratti hundaa'uun jijjirama addaa ni gorsa.

Waraqaa walitti bu'iinsa dhiigaa, Factor IX kennamuu, fi bu'aawwan gama tokkoon tokkoon isaa sirnaan qabachuun gareen yaala fayyaa kee karoora yaala kee fooyyessuuf ni gargaara. Namoonni baay'een appiiwwan addaa ykn barruulee hemophilia to'achuuf qophaa'an fayyadamu.

Yaalli fayyaa dhukkuba Factor IX maalii dha?

Yaalli fayyaa inni guddaan hemophilia B Factor IX bakka buusuudha. Doktarri kee gosaa fi doozii sirrii ta'e sadarkaa Factor IX kee, seenaa dhiigaa, fi barbaachisummaa jireenya kee irratti hundaa'uun murteessa. Yaalli yeroo dhiigni dhufu kennamuu ykn akka prophylaxisitti walitti bu'iinsa dhiigaa ittisuuf kennamuu danda'a.

Yaala barbaachisaa ta’e jechuun, yeroo dhiigni itti yaa’u ykn hojiiwwan dhiiga itti yaa’uu danda’an dura, Factor IX argatta. Tooftaan kun namoota hemophilia B salphaa qabaniif ykn warra yeroo muraasa dhiigni itti yaa’uuf gaarii ta’a. Doktarri kee qoricha safara qaamaa keetii fi hammeenya dhiiga yaa’uu irratti hundeeffachuun shallaga.

Yaalli ittisaa, Factor IX yeroo hunda sirnaan kennuun dhiiga kee keessatti sadarkaa eegumsa qabu eeguu dabalata. Tooftaan kun yeroo baay’ee namoota hemophilia B cimaa qabaniif ykn warra yeroo baay’ee walitti dhiigni itti yaa’uuf ni gorfama. Factor IX kan glycopegylated jedhamu yeroo baay’ee hin kennamu, yeroo tokko tokko giddugala yaala gidduutti yeroo dheeraa kennuun ni danda’ama.

Karoora yaala kee keessatti yaalawwan deeggarsa dabalataa ni argatta. Kunis fayyaa waljijjiirraa eeguuf yaala qaamaa, dhukkubbii ykn barooda to’achuuf qorichoota, fi qorannoo dhiigaa yeroo hunda Factor IX sadarkaa gaarii ta’e akka qabaattu mirkaneessuuf ni dabalata.

Yoom Factor IX hir’achuu irraa kan ka’e doktaratti argamuu qaba?

Mallattoolee dhiiga cimaa yoo argatte, yeroo ammaa yaala Factor IX argattus, dafee ogeessa fayyaa kee qunnamuu qabda. Kunis mataa cimaa, jijjiirama mul’ata, dhukkubbii garaa yeroo hundaa, ykn dhiiga yaa’uu yaala keetiin hin deebine ni dabalata.

Haala kee hordofuu fi karoora yaala kee akka barbaachisumatti sirreessuuf walgahii hordoffii yeroo hunda qabadhu. Doktarri kee yeroo baay’ee ji’a 3-6 keessatti akka si argu barbaada, akkaataa dhiigni itti yaa’u ilaaluuf, rakkoolee ilaaluuf, fi yaalli Factor IX bakka bu’aa kee akka hojjetu mirkaneessuuf.

Qorannoo sirna yaalaa, yaala ilkaan ykn yaala fayyaa kamiyyuu dura garee fayyaa kee waliin wal qunnamu. Haalli kun yeroo baay’ee dhiigni akka hin yaanetti ittisuuf qoricha Factor IX addaa barbaada. Doktarri kee ogeessota fayyaa biroo waliin walii galuun yaala nageenya qabu fi bu’a qabeessa ta’e akka argattu ni mirkaneessa.

Yoo mallattoowwan haaraan ykn jijjiirama qaamni kee dhiiga akka dhiisu gochuu hubatte, doktaroota kee qunnamuu hin shakkinaa. Kunis yeroo baay'ee dhiiguu, bakka haaraatti dhiiguu, ykn akkaataa itti yaala Faaktara IX itti deebistuu jijjiiramaa dabalata. Yeroon dursanii walitti dhufuun rakkoolee ittisuu fi kunuunsa kee fooyyessuu danda'a.

Maal fa'i dhaabbanni Faaktara IX dhabuu kan dhufan?

Wantoonni balaa guddaan Faaktara IX dhabuu maatii kee keessatti seenaa dhiiga dhiiguu B qabaachuu dha. Haalli kun kromozomii X irraa kan dhaalamu waan ta'eef, dhiirota irratti baay'inaan ni mul'ata, dubartoonni immoo baay'inaan akka geejjibaa ta'u. Yoo haati kee geejjibaa taate, carraa %50 jiinii jijjiirame dhaaluu qabda.

Dhiira dhalachuun yoo jiinii jijjiirame dhaalte balaa dhiiga dhiiguu B kan mallattoon isaa mul'atu akka qabaattu siif dabala. Dubartoonnis ni miidhamuu danda'u, garuu kun baay'ee hin baratamne yoo ta'u yeroo jiinii jijjiiramee warra lamaan irraa dhaalan ykn jijjiirama kromozomii tokko tokko qabaatanitti ta'a.

Haalli fayyaa tokko tokko yeroo booda jireenya keessatti balaa Faaktara IX dhabuu akka qabaattu ni dabala. Kunis dhukkuboota ofii of irratti xiyyeeffatan kan qaamni kee faaktaroota dhiiga itti walitti qabuu of irratti weeraru, dhukkuba tiruu cimaa kan oomisha faaktara dhiiga itti walitti qabuu itti dhorku, fi qorichoota tokko tokko kan dhiiga itti walitti qabuu irratti dhiibbaa qaban dabalata.

Umriin Faaktara IX dhabuu kan argamu irrattis gahee taphachuu danda'a, akkuma haalli ofii of irratti xiyyeeffatan tokko tokko kan faaktaroota dhiiga itti walitti qabuu irratti dhiibbaa qaban umrii dabaluu wajjin baay'achaa deemu. Haa ta'u malee, dhiiga dhiiguu B kan jiinii irraa dhufan dhalootarraa kan jiru yoo ta'u, mallattoon isaa yeroo booda jireenya keessatti mul'achuu danda'a.

Rakkoolee Faaktara IX dhabuu kan danda'aman maal fa'i?

Miidhaan walii galaa rakkoolee yeroo dheeraa Faaktara IX dhabuu kan hin yaalamne keessaa tokko dha. Dhiiguun walitti aansee walii galaa keessatti, keessumaa jilba, miillaa, fi qoma, dhukkubbii yeroo dheeraa, cimaa ta'uu, fi sochii hir'isuu ni danda'a. Haalli kun, arthropaatii hemofiliikii jedhama, yoo sirriitti hin bulfamin qulqullina jireenya kee irratti dhiibbaa guddaa geessisuu danda'a.

Dhiigni keessaa rakkoo guddaa biraa agarsiisa, keessumaa dhiiga sammuu, garaacha, ykn qaama qomaatti dhangala'uun. Haalli dhiigni itti dhangala'uun kun jireenya sodaachisaa ta'uu danda'a, kunis xiyyeeffannaa wal'aansaa hatattamaa barbaada. Dhiigni sammuu keessatti dhangala'uun mataa dhukkessuu, wal'aansoo dhabuu, ykn mallattoolee narvii fiduu danda'a, yoo dhiigni garaacha keessatti dhangala'uun immoo dhukkubbii cimaa fi miidhaa qaama keessaa fiduu danda'a.

Dhiigni maashaalee keessatti dhangala'uun, ykn heematoomaan, narvii fi hidda dhiigaa walitti qabuu danda'a, kunis dhukkubbii, qaama hir'achuu, ykn hojii naannoo miidhametti hir'isuu geessa. Dhiigni maashaalee gurguddoo keessatti dhangala'uun wal'aansa suukoo barbaachisa, dhiibbaa salphisuufi miidhaa yeroo hundaa ta'u ittisuuf.

Namoonni hanqina Faaktara IX qabanis yeroo wal'aansa fayyaa, daa'ima godhachuu, ykn miidhaa irra ga'uun balaa guddaa keessa galu. Utuu Faaktara IX sirriitti hin bakka bu'in, haalli kun dhiigni baay'ee akka dhangala'u kan to'achuun ulfaatu fiduu danda'a. Haa ta'u malee, qindoomina wal'aansaa sirriitiin, balaawwan kun to'annaa gaariin bulfamu.

Yeroo muraasa keessatti, namoonni tokko tokko inhibitoorota - qaamolee dhukkuba ittisuu kan Faaktara IX bakka bu'uun akka hin hojjanne godhan - horatu. Rakkoon kun tooftaalee wal'aansaa addaa fi hordoffii dhiigaa ogeeyyii heemofiliyaan wal qabatu barbaada.

Wal'aansi bakka bu'iinsa Faaktara IX heemofilii B'f gaarii moo badaa?

Wal'aansi bakka bu'iinsa Faaktara IX namoota heemofilii B qabaniif faayidaa guddaa qaba, kunis wal'aansa sadarkaa warqee agarsiisa. Qorichi kun dhiigni akka hin dhangalaane, miidhaa waljijjiirraa hir'isuun, fi hojiiwwan baay'ee idileetti nageenyaan hirmaachuu akka dandeessan gochuun qulqullina jireenya keessanii guddisuu danda'a.

Wal'aansi kun kan hojjetu Faaktara IX pirootiinii qaama keessanii dhiiga akka itti walitti qabuuf barbaadu kan hin jirre ykn miidhametti bakka bu'uudhaan. Wal'aansi yeroo hundaa ta'u miidhaa waljijjiirraa fi dhukkubbii yeroo dheeraa kan heemofilii B wal'aansa malee yeroo turu uumamu ittisuu danda'a. 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Oomota Factor IX ammayyaa, keessumaayyuu kanneen glycopegylated jedhaman, salphina fooyya'aa kan qaban yoo ta'u, kan yeroo dheeraaf turu. Kunis sirna walitti aansuun sirna qoricha itti fayyadamuu xiqqeessuu fi dhiigni akka hin yaane ittisuu jechuudha. Qorichi kun yeroo garee fayyaa keessaniin akka isinitti himametti itti fayyadamtan, nageenya gaarii qaba.

Yoo terapiin Factor IX bakka bu'uun faayidaa guddaa qabaatus, karoora yaala keessan sirritti hordofuu fi walitti dhufeenya yeroo hunda wal'aantota fayyaa keessanii wajjin qabaachuun barbaachisaa dha. Itti fayyadama qoricha kanaa sirrii ta'e fayyadamuun, hemophilia B qabaachuu keessaniin kan ka'e, jireenya fayyaa fi nagayaa jiraachuu isin gargaara.

Maalif hanqina Factor IX dogoggoraan ilaalamuu danda'a?

Hanqina Factor IX yeroo tokko tokko dhukkuboota dhiigni itti yaa'u biroo, keessumaayyuu hemophilia A (hanqina Factor VIII) wajjin walitti makamuu danda'a. Haalli lamaanuu mallattoowwan dhiigni itti yaa'u wal fakkaatan kan qaban yoo ta'an, garuu wantoota dhiiga itti walitti qaban adda addaa kan fayyadamanii fi terapiis bakka bu'aa adda addaa kan barbaadan ta'aniidha. Qorannoon dhiigaa sirrii ta'e gidduu isaanii addaan baasuu danda'a.

Dhukkubni Von Willebrand, dhukkuba dhiigni itti yaa'u kan dhaalamu kan baay'ee argamu, mallattoowwan wal fakkaatan agarsiisuu danda'a. Haa ta'u malee, haalli kun yeroo baay'ee dhiiraa fi dubartoota wal qixa kan tuqu yoo ta'u, yeroo baay'ee mallattoowwan dhiigni itti yaa'u adda addaa kan qabu, akka yeroo laguu ulfaataa ykn miidhama salphaatti qaama irraa argamu.

Rakkoowwan platelet Factor IX hanqina wajjin walitti makamuu danda'u sababiin isaas lamaanuu miidhama salphaa fi dhiigni akka yaa'u sababa ta'uu danda'u. Haa ta'u malee, rakkoowwan platelet yeroo baay'ee bakkeewwan dhiigni itti yaa'u xiqqaa, kan petechiae jedhamu, kan sababa ta'u yoo ta'u, hanqina Factor IX garuu yeroo baay'ee dhiigni keessa gadi fagoo ta'ee wal ijootti fi maashaatti akka yaa'u sababa ta'a.

Yeroo tokko tokko, dhukkubni tiruu ykn hanqina vitamin K Factor IX hanqina fakkaachuu danda'a, wantoota dhiiga itti walitti qaban hedduu irratti dhiibbaa waan qabuuf. Doktarri keessan qorannoowwan dhiigaa bal'aa fi xiinxala seenaa fayyaa fayyadamuun haala kana addaan baasuu danda'a.

Ijoollee keessatti, hanqina Faaktara IX jalqaba irratti miidhaa daa'immaniif kan dogoggoraan ilaalamu ta'uu danda'a sababa miidhama ykn dhiigni hin ibsamne. Haa ta'u malee, fakkeenyi dhiigni addaa fi seenaan maatii yeroo baay'ee ogeeyyiin fayyaa akka sirnaan hubatan gargaara.

Gaaffiiwwan yeroo baay'ee waa'ee hanqina Faaktara IX gaafatamaniin

Yaalli Faaktara IX qaama koo keessatti hangam turuu danda'aa?

Foomiin glycopegylated Faaktara IX yeroo baay'ee dhiiga keessatti kan turu oomisha Faaktara IX aadaa caalaa. Akkaataa qaama keessaa keessatti walnyaatinsa fi oomisha addaa itti fayyadamtan irratti hundaa'uun, eegumsi guyyoota muraasaa hanga torban tokkoo olitti turuu danda'a. Doktarri keessan sagantaa qoricha sirrii ta'e sadarkaa Faaktara IX fi fakkeenya dhiigaa irratti hundaa'uun murteessa.

Faaktara IX hanqina qabaadhee ispoortii hojjechuu ykn taphachuu nan danda'aa?

Eeyyee, yaala bakka bu'aa Faaktara IX sirnaan fi qajeelfama fayyaa waliin, hojiiwwan qaamaa fi ispoortii hedduu irratti hirmaachuu dandeessu. Gareen fayyaa keessan hojiiwwan balaa guddaa qaban dura qoricha Faaktara IX sirrii ta'e itti fayyadamuun karoora hojii akka qabaattan isin gargaara. Suuqii, siikilii fi miillaan deemun waliigalaan amansiisaa akka ta'etti ilaallama, yoo taphoota walitti dhufeenyaa garuu eegumsi addaa barbaachisa ta'uu danda'a.

Jireenya koo guutuu yaala Faaktara IX nan barbaadaa?

Yoo hemophilia B dhalaan qabaattan, jireenya keessan guutuu yaala bakka bu'aa Faaktara IX barbaachisuu dandeessu. Haa ta'u malee, akka yaalli haaraan fi teeknooloojii argamanitti, yaalli jijjiramuu danda'a. Gareen fayyaa keessan akka barbaachisummaa keessanitti, kunuunsa gaarii akka argattanif yeroo hunda yaala keessan ni ilaaluu fi ni sirreessu.

Nyaata ykn qoricha yaala Faaktara IX waliin ittisuu qabuun jiraa?

Akkaataa waliigalaatti, yaala Factor IX wajjin wantoota nyaata adda ta'an hin qaban. Haa ta'u malee, qorichoota dhiigni akka itti hin dhangalaane godhan, akka aspirin ykn qorichoota dhukkubbii tokko tokko, yoo ogeessa fayyaan keessan hin eeyyaminitti of eeggachuu qabdu. Qorichoota haaraa kamiyyuu jalqabuu keessan dura, ogeessota fayyaa keessanitti waa'ee hemophilia B fi yaala Factor IX keessanii beeksisuu qabdu.

Dubartoonni hanqina Factor IX qabaachuu danda'u?

Eeyyee, garuu baay'ee hin argamu, dubartoonni hanqina Factor IX qabaachuu danda'u. Kun kan uumamuu danda'u yeroo maatiin lamaan irraa geenota jijjiramanii dhaalan ykn jijjirama kromosoomii tokko tokko qabaatanidha. Dubartoonni baattoota ta'an mallattoowwan dhiigni dhangala'uu ni muudatu, keessumaa yeroo laguu, da'umsa ykn sirna yaalaa, akkasumas haala kana keessatti yaala Factor IX irraa faayidaa argachuu danda'u.