Twageze kuki ku gukira SIDA?

Nta mwanya wo gukira burundu SIDA irahari, ariko abashakashatsi barimo bakora intambwe zidasubirwaho. Birashoboka ko waje hano kuko wowe cyangwa umuntu mukundana bafite SIDA, kandi ushaka kumenya niba hari ibyiringiro koko ku gasongero. Igisubizo gito ni yego, abahanga barimo bakora uburyo bwinshi bwo kugoboka bushobora kuzakurura virusi mu mubiri wawe umunsi umunsi. Ubu, dufite imiti myiza cyane igumisha virusi mu bwihisho kandi igatuma ubaho ubuzima buzira inenge.

Kwakira SIDA Bisobanura Iki Mu By'ukuri?

Gukira bisobanura gukuraho burundu virusi ya SIDA mu mubiri wawe kugira ngo itagaruke ukundi. Ibi bitandukanye n'ibyo imiti yacu ikora ubu, aho igumisha virusi mu maboko. Herpes simplex virus, cyangwa HSV, ihisha mu nkomamashyi aho sisitemu y'umubiri wawe n'imiti myinshi idashobora kugerayo. Ituma yihisha, cyangwa yiryamye, kugeza igihe ikintu gikimwibutsa cyo kwibuka no gutera icyorezo.

Imiti ya antiviral nka acyclovir, valacyclovir, na famciclovir ikora neza mu guhagarika virusi kwiyongera. Igabanya ibiza, ikorohesha ibimenyetso, kandi ikagabanya amahirwe yo kwanduza virusi ku muntu. Ariko ntibakuraho virusi mu nkomamashyi zawe. Ni byo abashakashatsi barimo bashaka guhindura.

Kuki SIDA Ikomeye Kwihanganira?

Virusi ya SIDA irakomeye mu kwihisha. Iyo imaze kwinjira mu mubiri wawe, igenda mu nkomamashyi hafi y'umugongo wawe kandi igahagarara. Inkomamashyi ni nk'inzu z'umutekano aho virusi ishobora kwihisha amezi cyangwa imyaka myinshi. Sisitemu y'umubiri wawe irabika umubiri wawe ishaka abagabanyi, ariko ifite akazi gakomeye ko kubona virusi zihishwe mu nkomamashyi.

Iyo virusi ihishwe, ntibigana virusi cyangwa igikoresho cyayo. Bivuze ko sisitemu y'umubiri wawe idayibona nk'ikibazo. Ibi kandi bisobanura ko imiti myinshi ya antiviral, ikora mu guhagarika virusi kwiyongera, nta cyo ikwiranyeho. Virus ntikora ibintu byinshi igihe yiryamye.

Ikindi kibazo ni uko DNA ya SIDA yinjira mu bikoresho by'umubiri wawe mu nkomamashyi zawe. Iba igice cy'inshuti mu buryo bukomeye kugirango ikurweho nta kwangiza inkomamashyi ubwayo. Abahanga bagomba kubona inzira yo kwibuka buri virusi yihishe kandi bakayikuraho, cyangwa bakakuraho DNA ya virusi nta kwangiza ingirakamaro zawe.

Ni Ubuhe Buvuzi Dufite?

Mbere yuko tuvuga ku kwirinda ejo, bifasha gusobanukirwa ibikorwa by'ibimaze kugira akamaro ku bantu miliyoni. Imiti ya antiviral ya none irakingiye, irakora, kandi irahari cyane. Bashobora kugabanya cyane umubare w'ibibazo uhura nabyo kandi bakagabanya ibimenyetso mu gihe bibaye. Abantu benshi bafata imiti ya buri munsi, bivuga gufata ikinini buri munsi kugira ngo virusi ikomeze mu bwihisho.

Imiti ishobora kandi kugabanya akaga ko kwanduza SIDA ku mukunzi wawe kuri 50% igihe yahujwe n'indi mikorere yo kwirinda. Ni itandukaniro rikomeye. Niba uba na SIDA ubu, ufite ibikoresho bikora. Ntibagirira kwandura, ariko bikubaha ubuyobozi bwabyo.

Ni Ubuhe Abahinga Barimo Gukora?

Imiti Y'imikoro

Gukoresha imikoro ni kimwe mu bintu byiza cyane mu bushakashatsi bwa SIDA. Abahinga bakoresha ibikoresho nk'umwanya wa CRISPR, uba nk'udushyiramo nk'udushyiramo, kugirango bakureho DNA ya SIDA mu nkomamashyi zanduye. Mu bushakashatsi bwa laboratoire n'imigabane y'inyamaswa, abashakashatsi bashoboye gukuraho igice cya DNA ya virusi kandi bagahagarika virusi kwibuka. Iki gikorwa kiracyari mu ntangiriro, ariko ibisubizo kugeza ubu birashimishije.

Ikibazo gikomeye cyo gukoresha imikoro ni gutanga imiti mu buryo bwo kwirinda mu nkomamashyi zose zihishe virusi. Inkomamashyi zihagaze mu mubiri wose, kandi kugera kuri buri nshuti yanduye ntibyoroshye. Abahinga barimo bashakashatsi ibindi virusi, bita vectors, bashobora gutwara ibikoresho by'imikoro mu nkomamashyi nta kwangiza. Bamwe muri ubu buryo bwo gutanga barimo bageragezwa mu nyamaswa.

Imirimo y'abantu y'imiti y'imikoro birashoboka ko izaba mu myaka mike. Abahinga bagomba kwemeza ko imiti irakingiye, irakora, kandi itangiza DNA nziza mu buryo bw'impamvu. Ariko iki gikorwa gifite ubushobozi bukwiriye kugirira akamaro.

Imiti Y'ubudahangarwa

Ikindi gikorwa gishimishije ni ugushyiraho sisitemu y'umubiri wawe kugira ngo ibone kandi ikureho virusi yihishe. Bamwe mu bashakashatsi barimo bakora imiti ya therapeutic vaccines itozwa sisitemu y'umubiri wawe kwibuka no kurwanya inkomamashyi zanduye na SIDA. Bitandukanye n'inkingo zo kwirinda, utanga mbere yuko wandura, inkingo za therapeutic zitangwa nyuma yuko umaze kwandura.

Izi nkingo zikora mu kwigisha T cells zawe, ubwoko bw'ingirakamaro, kwibuka ibintu by'ingenzi bikorwa na virusi ya SIDA. Iyo zimaze kwigishwa, T cells zawe zishobora gukora umubiri wawe kandi zikuraho inkomamashyi zose zatangiye gukora ibintu by'ingenzi bya virusi. Ubushakashatsi bwa mbere bwerekanye ko inkingo za therapeutic zimwe na zimwe zishobora kugabanya umubare w'ibibazo kandi zikagabanya ububare bwa virusi mu mubiri.

Inkingo z'ubushakashatsi kimwe bita DNA vaccine zagaragaje ubushobozi mu bushakashatsi bw'inyamaswa. Ikoresha igice cya DNA ya SIDA kugira ngo ishyireho sisitemu y'umubiri nta kwanduza. Ikindi gikorwa gikoresha virusi z'ubuzima ariko zihishe kugira ngo zitere ubukomeye bwo kwirinda. Imirimo y'abantu irahari kuri izi nkingo nyinshi, kandi ibisubizo bigomba kuboneka mu myaka mike iri imbere.

Imiti Itera Virus Yibuka

Bamwe mu bashakashatsi barimo bakoresha ikindi gikorwa mu kigerageza gutera virusi yiryamye kwibuka. Iki gitekerezo ni ugukoresha imiti itera virusi gutangira kwiyongera. Iyo virusi igikora, iba irakingiye ku miti ya antiviral na sisitemu y'umubiri wawe. Iki gikorwa rimwe na rimwe gitwa "shock and kill".

Mu bushakashatsi bwa laboratoire, abahinga bagerageje imiti ishobora kwibuka SIDA mu nkomamashyi. Igihe yahujwe n'imiti ya antiviral ikomeye, iki gikorwa cyagabanyije ububare bwa virusi yihishe. Ikibazo cyo kwemeza ko imiti itera virusi kwibuka buri virusi yihishe icyarimwe, ntabwo ari kimwe gusa. Niba hari na copies nke za virusi zihishe, zishobora gutera ibibazo byongeye nyuma.

Iki gikorwa kiracyageragezwa mu nyamaswa, kandi bizafata igihe kugira ngo tubone niba gikora mu buryo bwo kwirinda mu bantu. Abahinga bagomba kwemeza ko gutera virusi kwibuka bidatera ibibazo bikomeye cyangwa ibindi bibazo.

Inkingo Zo Kwirinda

N'ubwo atari kwirinda, inkingo zo kwirinda zishobora guhagarika kwanduza SIDA mu ntangiriro. Amakipe menshi arimo gukora inkingo zizaringaniza abantu batigeze bahura na virusi. Niba zikora, izi nkingo zishobora kugabanya umubare w'abandura bashya buri mwaka.

Kwakira inkingo za SIDA byaragoranye kuko virusi iruta ingabo zo kwirinda umubiri. Imirimo y'inkingo ya mbere ntiyagize icyo ikora, ariko abahinga bamenye byinshi kuri ayo masezerano. Ibisubizo bishya bikoresha ikoranabuhanga rya none kandi bigamije ibice bitandukanye bya virusi. Imirimo imwe irimo kwibanda ku nkingo zizaringaniza HSV 1 na HSV 2, ubwoko bubiri bwa SIDA.

Ni Igihe Kingana Gute Kugira Ngo Kwirinda Kuboneke?

Imirimo ya kliniki iba mu ngingo. Imirimo ya 1 igenzura kwirinda mu itsinda rito ry'abantu. Imirimo ya 2 yibanda ku ngingo yo kwirinda n'ibipimo byiza. Imirimo ya 3 irimo abantu ibihumbi kandi igakuranya imiti nshya n'ibindi bikoresho byo ubu. Buri ngingo ishobora gufata imyaka myinshi. Nyuma yaho, ibiro by'amategeko nk'umuryango wa FDA bisubiramo amakuru mbere yo kwemerera imiti.

Imiti y'imikoro n'inkingo za therapeutic zirahari mu ngingo za mbere cyane. Bamwe mu miti yo kwirinda bagereye mu ngingo za 2, bivuga ko abahinga batangiye kubona niba ikora mu bantu. Birashoboka ko kimwe muri ibi bikorwa cyajya kwemerwa mu myaka icumi iri imbere, ariko nta ngwano.

Ni Ubuhe Ushobora Gukora Ugiye Kwirinda?

Kubaho na SIDA ubu ntibisobanura kwirinda ubuzima bwawe kugeza kwirinda biboneka. Ufite uburyo bwiza bwo gukemura ibimenyetso no kwirinda ubuzima bwawe. Gufata imiti ya antiviral buri munsi ishobora kugabanya ibibazo no kugabanya akaga ko kwanduza. Abantu benshi basanga ibibazo byabo bigenda bigabanuka mu gihe, n'ubwo nta kwirinda.

Stress, indwara, no kutaryama neza byateza ibibazo, bityo kwita ku buzima bwawe bwose ni ingenzi. Kurya neza, kuruhuka bihagije, no kwirinda stress byafasha virusi kwibuka. Ushobora kandi gusanga bifasha kwifatanya n'itsinda ryo kwifashisha cyangwa umujyanama wumva uko wumva. SIDA irasanzwe cyane, ikagira ingaruka ku bantu bagera kuri umwe muri batandatu, kandi nturi wenyine.

Birakwiriye kandi kuguma ufite amakuru ku bushakashatsi bushya. Imirimo ya kliniki irimo igishakisha abazitabira, kandi kwitabira imirimo ishobora gutuma ugira uburyo bwo kwirinda bwo hejuru kandi ugatuma abahinga bagera kuri kwirinda. Ushobora kubaza muganga wawe niba hari imirimo ishobora kugufasha.

Icyo Twavuga

Kutagira kwirinda ubu ntibisobanura ko nta byiringiro. Abahinga barimo bakora intambwe zikomeye, kandi ibikorwa bigeragezwa ni byiza kuruta ibyo twigeze tubona. Imikoro, imiti yo kwirinda, n'inkingo za therapeutic zose zifite ubushobozi bwo guhindura isura yo kuvura SIDA. Bamwe muri bino bikorwa bashobora no guhurirana kugira ngo babone ibisubizo byiza.

Mu gihe utegereje, wibuke ko SIDA ari indwara ishobora gukemurwa. Ntibigufasha, kandi ntibigomba kugabanya ubuzima bwawe. Abantu benshi bafite SIDA babayeho ubuzima bwuzuye, imiryango irimo ubuzima, n'imirimo ikomeye. Imiti ihari ubu irakora, kandi ibishya birahari.

Ushobora gutanga amakuru meza, ubufasha bw'impuhwe, n'ibyiringiro by'ejo hazaza. Komeza kwibaza, ugumane na muganga wawe, kandi witware. Kwirinda bishobora kutaboneka ubu, ariko biri hafi kuruta uko byigeze bibaho, kandi nturi wenyine utegereje.