Cancer, Uburibwe Bwa Carcinoid

Ubuye bwa karusinoide ni ubwoko bwa kanseri ikura buhoro buhoro ishobora kuvuka ahantu henshi mu mubiri wawe. Ubuye bwa karusinoide, buri mu bwoko bumwe bw'ubuyemo bwitwa ubuye bwa neuroendocrine, busanzwe butangira mu mara (igifu, umura, uruhinja, igice kinini cy'amara, umurama) cyangwa mu bihaha.

Ubuye bwa karusinoide akenshi ntibutera ibimenyetso kugeza igihe cya nyuma cy'indwara. Ubuye bwa karusinoide bushobora gukora no kubohora imisemburo mu mubiri wawe itera ibimenyetso nka diarehe cyangwa umutuku ku ruhu.

Ubuvuzi bw'ubuyemo bwa karusinoide busanzwe burimo kubaga kandi bushobora kuba burimo imiti.

Umuti w'ibisebe bimwe na bimwe ntabwo uterwa n'ibimenyetso cyangwa ibimenyetso. Iyo bibayeho, ibimenyetso n'ibimenyetso bikunze kuba bidafatika kandi biterwa n'aho uwo muti uri.

Ibimenyetso n'ibimenyetso by'ibisebe bya karisinoide biri mu bihaha birimo:

• Kubabara mu kifuba
• Guhumeka bikomeye
• Guhumeka nabi
• Impiswi
• Ububara cyangwa ubushyuhe mu maso no mu ijosi (uruhu rutukura)
• Kugira ibiro, cyane cyane mu gice cy'inda no mu mugongo wo hejuru
• Ibimenyetso by'umutuku cyangwa umuhondo ku ruhu bisa n'ibimenyetso byo kwaguka

Ibimenyetso n'ibimenyetso by'ibisebe bya karisinoide biri mu nzira y'igogorwa birimo:

• Kubabara mu nda
• Impiswi
• Isesemi, kuruka no kudashaka kujya ku musarani kubera inzitizi mu mara (inzitizi mu mara)
• Umuvuduko w'amaraso mu kibuno
• Kubabara mu kibuno
• Ububara cyangwa ubushyuhe mu maso no mu ijosi (uruhu rutukura)

Niba ufite ibimenyetso n'ibibonwa bikubabaza kandi bikomeza igihe kirekire, hamagara muganga wawe. Kanda kuri "subscribe" ubuntu, maze ubone igitabo cyerekana uko wakwirinda kanseri, ndetse n'amakuru y'uko wakwemererwa kujya kubona undi muganga. Ushobora gukuramo izina ryawe kuri iyi service igihe icyo aricyo cyose. Igitabo cyerekana uko wakwirinda kanseri kizaba kiri muri inbox yawe mu kanya gato. Uzabona kandi

Ntabwo birasobanutse icyateza uburwayi bwa carcinoid. Muri rusange, kanseri ibaho iyo akagira kagize impinduka muri ADN yacyo. Izi mpinduka zemerera akagira gukomeza gukura no kwibyarira mu gihe utundi tugira twiza twapfa. Utu tugira dutangira gukusanyiriza hamwe tugakora igihingwa. Utu tugira twa kanseri dushobora kwangiza imyanya y'ubuzima ibiri hafi no gukwirakwira mu bindi bice by'umubiri.

Abaganga ntibabizi icyateza impinduka zishobora gutera uburwayi bwa carcinoid. Ariko bazi ko uburwayi bwa carcinoid buterwa n'utugira twa neuroendocrine.

Utu tugira twa neuroendocrine tuboneka mu ngingo zitandukanye z'umubiri. Dukora imirimo imwe y'uturemangingo tw'imbere n'imirimo imwe yo gukora imisemburo y'uturemangingo tw'imisemburo. Imwe mu misemburo ikorwa n'utugira twa neuroendocrine ni histamine, insuline na serotonin.

Ibintu byongera ibyago byo kurwara uburwayi bwa carcinoid tumors birimo:

• Urukoko rukuze. Abantu bakuze bafite ibyago byinshi byo kubonwa bafite uburwayi bwa carcinoid tumors ugereranyije n'abakiri bato cyangwa abana.
• Ibitsina. Abagore bafite ibyago byinshi kurusha abagabo byo kurwara uburwayi bwa carcinoid tumors.
• Amateka y'umuryango. Amateka y'umuryango afite uburwayi bwa multiple endocrine neoplasia, ubwoko bwa 1 (MEN 1), yongera ibyago byo kurwara uburwayi bwa carcinoid tumors. Mu bantu bafite MEN 1, habaho uburwayi bwinshi mu mitsi y'ubwonko ikora imisemburo.

Uturambuye tw'ibitumwa bya carcinoid dushobora gukora imisemburo n'izindi chemicals, bigatera ibibazo bitandukanye birimo:

• Indwara ya Carcinoid. Indwara ya Carcinoid itera uburyo bw'umutuku cyangwa ubushyuhe mu maso no mu ijosi (kwishima kw'uruhu), impiswi zidakira, no kugorana guhumeka, mu bindi bimenyetso n'ibibonwa.
• Indwara y'umutima iterwa na Carcinoid. Ubumara bwa Carcinoid bushobora gukora imisemburo ishobora gutera ukubyimbirwa kw'urugingo rw'imbere mu byumba by'umutima, imivure n'imitsi y'amaraso. Ibi bishobora gutera imivure y'umutima idafunze neza n'i gucika intege kw'umutima bishobora gusaba kubagwa kugira ngo imivure ihindurwe. Indwara y'umutima iterwa na Carcinoid ishobora guhagararirwa hakoreshejwe imiti.
• Indwara ya Cushing. Ubumara bwa Carcinoid mu muhogo bushobora gukora imisemburo myinshi ishobora gutera umubiri wawe gukora imisemburo myinshi ya cortisol.

Ibizamini n'uburyo bikoreshwa mu kumenya ibibyimba bya carcinoid birimo:

• Ibizamini by'amaraso. Niba ufite ibibyimba bya carcinoid, amaraso yawe ashobora kuba afite urugero rwinshi rw'imisemburo isohorwa n'ibibyimba bya carcinoid cyangwa ibinyabutabire bikorwa iyo iyo misemburo isenyutse mu mubiri.
• Ibizamini by'umushitsi. Abantu bafite ibibyimba bya carcinoid bafite urugero rwinshi rw'ikinyabutabire mu mushitsi wabo gikorerwa iyo umubiri usenyuye imisemburo isohorwa n'ibibyimba bya carcinoid.
• Ibizamini byo kubona ishusho. Ibizamini byo kubona ishusho, birimo scan ya computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), X-ray na scan za nuclear medicine, bishobora gufasha muganga wawe kumenya aho ibibyimba bya carcinoid biherereye.
• Gukuramo umubiri kugira ngo ukorerwe ibizamini bya laboratoire. Igice cy'umubiri kivuye mu kibyimba (biopsy) gishobora gukurwa kugira ngo hamenyekane neza icyo urwaye. Uburyo bwo gukuramo igice cy'umubiri biterwa n'aho kibyimba giherereye.

Uburyo bumwe bwo gukuramo igice cy'umubiri bukoresha igikoresho cyo kubona utunyangingo mu kibyimba. Ubundi buryo bushobora kuba ari ubuvuzi. Umubiri woherezwa muri laboratoire kugira ngo hamenyekane ubwoko bw'utunyangingo turi mu kibyimba n'uburyo butera ubwoba utwo tunyangingo tuboneka kuri microscope.

Igisoko cyangwa camera iboneka imbere mu mubiri wawe. Muganga wawe ashobora gukoresha umuyoboro muremure, muto ufite lens cyangwa camera kugira ngo asuzume ibice biri imbere mu mubiri wawe.

Endoscopy, irimo gushyira igisoko mu mazuru yawe, ishobora gufasha muganga wawe kubona imbere mu mara yawe. Bronchoscopy, ikoresha igisoko gishyirwa mu mazuru yawe no mu bihaha byawe, ishobora gufasha kubona ibibyimba bya carcinoid byo mu bihaha. Gushyira igisoko mu kibuno cyawe (colonoscopy) bishobora gufasha kumenya ibibyimba bya carcinoid byo mu kibuno.

Kugira ngo ubone imbere mu mara mato yawe, muganga wawe ashobora kugusaba ikizamini gikoreshwa na camera ingana n'ipiluli uyanywa (capsule endoscopy).

Gukuramo umubiri kugira ngo ukorerwe ibizamini bya laboratoire. Igice cy'umubiri kivuye mu kibyimba (biopsy) gishobora gukurwa kugira ngo hamenyekane neza icyo urwaye. Uburyo bwo gukuramo igice cy'umubiri biterwa n'aho kibyimba giherereye.

Uburyo bumwe bwo gukuramo igice cy'umubiri bukoresha igikoresho cyo kubona utunyangingo mu kibyimba. Ubundi buryo bushobora kuba ari ubuvuzi. Umubiri woherezwa muri laboratoire kugira ngo hamenyekane ubwoko bw'utunyangingo turi mu kibyimba n'uburyo butera ubwoba utwo tunyangingo tuboneka kuri microscope.

Ubuvuzi bwa kanseri ya carcinoid buringira aho iherereye, niba kanseri yamaze gukwirakwira mu bindi bice by'umubiri, ubwoko bw'imisemburo imikira, ubuzima bwawe rusange n'ibyo ukunda. Amahitamo yo kuvura kanseri ya carcinoid ashobora kuba arimo:

• Ubuganga. Iyo imenyekanye hakiri kare, kanseri ya carcinoid ishobora gukurwaho burundu hakoreshejwe ubuganga. Niba kanseri ya carcinoid ari iya kure cyane igihe iboneka, kuyikuraho burundu bishobora kuba bidashoboka. Mu bihe bimwe na bimwe, abaganga bashobora kugerageza gukuraho igice kinini cy'ibyo bibyimba, kugira ngo bafashe kugenzura ibimenyetso n'ibibazo.
• Imiti yo kugenzura imisemburo y'umubiri. Gukoresha imiti yo guhagarika imisemburo isohorwa n'ibyo bibyimba bishobora kugabanya ibimenyetso n'ibibazo bya carcinoid syndrome no kugabanya ukwihuta kw'ibyo bibyimba. Octreotide (Sandostatin, Bynfezia Pen) na lanreotide (Somatuline Depot) bitangwa nk'injeksiyonu munsi y'uruhu. Ingaruka mbi z'imiti yombi zishobora kuba harimo ububabare mu nda, kubyimbagira no guhitwa. Telotristat (Xermelo) ni pilule ikoreshwa rimwe na rimwe hamwe na octreotide cyangwa lanreotide kugira ngo hageragezwe kurushaho kunoza ibimenyetso bya carcinoid syndrome.
• Chemotherapy. Chemotherapy ikoresha imiti ikomeye yo kwica uturemangingo tw'ibyo bibyimba. Ishobora gutangwa binyuze mu mutsi wo mu kuboko cyangwa ifatwa nk'ipilule. Chemotherapy rimwe na rimwe isabwa mu kuvura kanseri ya carcinoid ikomeye idashobora gukurwaho n'ubuganga.
• Ubuvuzi bwibanze ku miti. Ubuvuzi bwibanze ku miti bugerwa ku bintu bidasanzwe biri mu turemangingo tw'ibyo bibyimba. Mu guhagarika ibyo bintu bidasanzwe, ubuvuzi bwibanze ku miti bushobora gutuma uturemangingo tw'ibyo bibyimba dupfa. Ubuvuzi bwibanze ku miti busanzwe buhuzwa na chemotherapy mu kuvura kanseri ya carcinoid ikomeye.
• Imiti itanga imirasire mu buryo butaziguye mu turemangingo twa kanseri. Peptide receptor radionuclide therapy (PRRT) ihuza imiti ishaka uturemangingo twa kanseri hamwe n'ibintu by'imirasire bikayica. Muri PRRT yo kuvura kanseri ya carcinoid, imiti iterwa mu mubiri, aho ijya mu turemangingo twa kanseri, ikayifataho ikayitera imirasire mu buryo butaziguye. Ubu buvuzi bushobora kuba amahitamo ku bantu bafite kanseri ya carcinoid ikomeye.
• Ubuvuzi bwa kanseri ikwirakwira mu mwijima. Kanseri ya carcinoid ikunda gukwirakwira mu mwijima. Ubuvuzi bushobora kuba harimo ubuganga bwo gukuraho igice cy'umwijima, guhagarika amaraso ajya mu mwijima (hepatic artery embolization), no gukoresha ubushyuhe n'ubukonje bwo kwica uturemangingo twa kanseri. Radiofrequency ablation itanga ubuvuzi bw'ubushyuhe butuma uturemangingo twa kanseri ya carcinoid mu mwijima dupfa. Cryoablation ikoresha imizunguko yo gukonjesha no gushyuha kugira ngo yice uturemangingo twa kanseri. Imiti yo kugenzura imisemburo y'umubiri. Gukoresha imiti yo guhagarika imisemburo isohorwa n'ibyo bibyimba bishobora kugabanya ibimenyetso n'ibibazo bya carcinoid syndrome no kugabanya ukwihuta kw'ibyo bibyimba. Octreotide (Sandostatin, Bynfezia Pen) na lanreotide (Somatuline Depot) bitangwa nk'injeksiyonu munsi y'uruhu. Ingaruka mbi z'imiti yombi zishobora kuba harimo ububabare mu nda, kubyimbagira no guhitwa. Telotristat (Xermelo) ni pilule ikoreshwa rimwe na rimwe hamwe na octreotide cyangwa lanreotide kugira ngo hageragezwe kurushaho kunoza ibimenyetso bya carcinoid syndrome. Kwandikisha ubuntu hanyuma ubone igitabo cyimbitse cyo guhangana na kanseri, hamwe n'amakuru afatika yo kubona igitekerezo cya kabiri. Ushobora guhagarika kwandikisha igihe icyo aricyo cyose ukoresheje link yo guhagarika kwandikisha iri muri email. Igishushanyo cyawe cyimbitse cyo guhangana na kanseri kizaba kiri muri inbox yawe vuba. Uzabona kandi Buri muntu urwaye kanseri agira uburyo bwe bwite bwo guhangana. Ariko ntugomba kubikora wenyine. Niba ufite ibibazo cyangwa ushaka ubuyobozi, vugana n'umwe mu bagize itsinda ryawe rya serivisi z'ubuzima. Tekereza kandi ku ntambwe zikurikira kugira ngo ugire uruhare mu guhangana n'uburwayi bwawe:
• Menya amakuru ahagije kuri kanseri ya carcinoid kugira ngo ufate ibyemezo bijyanye no kwitaho kwawe. Baza muganga wawe ibibazo bijyanye n'uburwayi bwawe. Saba abagize itsinda ryawe rya serivisi z'ubuzima kugira ngo baguhe ibikoresho aho ushobora kubona amakuru y'inyongera.
• Genzura ibyo ushobora kugenzura ku buzima bwawe. Uburwayi bwa kanseri bushobora gutuma wumva nta kintu na kimwe ugenzura ku buzima bwawe. Ariko ushobora gufata ingamba zo kubungabunga ubuzima bwiza kugira ngo uhangane neza n'ubuvuzi bwa kanseri. Hitamo amafunguro azima yuzuye imbuto n'imboga. Iyo wumva ubikwiriye, shyiramo imyitozo yoroheje mu buzima bwawe bwa buri munsi. Gabanya umunaniro uko bishoboka. Rara uhagije kugira ngo wumve uhuye igihe ubyemeye. Genzura ibyo ushobora kugenzura ku buzima bwawe. Uburwayi bwa kanseri bushobora gutuma wumva nta kintu na kimwe ugenzura ku buzima bwawe. Ariko ushobora gufata ingamba zo kubungabunga ubuzima bwiza kugira ngo uhangane neza n'ubuvuzi bwa kanseri. Hitamo amafunguro azima yuzuye imbuto n'imboga. Iyo wumva ubikwiriye, shyiramo imyitozo yoroheje mu buzima bwawe bwa buri munsi. Gabanya umunaniro uko bishoboka. Rara uhagije kugira ngo wumve uhuye igihe ubyemeye.