Factor V Leiden ni iki? Ibimenyetso, Intandaro, n'Ubuvuzi

Factor V Leiden ni indwara y'umuzuko iterwa n'imiterere y'umuntu, ituma amaraso yawe akora ibinure byoroshye kurusha uko bikwiye. Ni yo ndwara ikunze kugaragara mu muryango y'amaraso akora ibinure, ikaba iboneka ku bantu bagera kuri 5% bafite inkomoko y'uburayi.

Iyi ndwara ibaho iyo warazwe impinduka runaka mu mbaraga za gene zituma amaraso yawe abuza ibinure gukora mu buryo busanzwe. Nubwo abantu benshi bafite Factor V Leiden batagira ibibazo, abandi bashobora kugira ibinure by'amaraso bishobora kuba bibi niba bitavuwe.

Factor V Leiden ni iki?

Factor V Leiden ni impinduka mu mbaraga za gene zigira ingaruka kuri poroteyine yitwa Factor V mu mikorere y'amaraso yawe. Iyi poroteyine isanzwe ifasha amaraso yawe gukora ibinure iyo wakomerekeye, hanyuma igahagarikwa n'indi poroteyine yitwa activated protein C.

Iyo ufite Factor V Leiden, poroteyine yahindutse irwanya guhagarikwa na activated protein C. Tekereza ko ari nk'igikoresho cyo guhagarika gukora ibinure cyakomeye ku mwanya wa "kuri." Ibi bituma amaraso yawe ashobora gukora ibinure nubwo utabikeneye.

Warazwa iyi ndwara mu babyeyi bawe binyuze mu mbaraga za gene. Ushobora kuzarwa kopi imwe y'impinduka ya gene cyangwa kopi ebyiri, ibyo bigira ingaruka ku buryo ushobora kugira ibinure by'amaraso.

Ibimenyetso bya Factor V Leiden ni ibihe?

Factor V Leiden ubwayo ntabimenyetso itera. Abantu benshi bafite iyi ndwara bumva bameze neza kandi bashobora kutamenya ko bayifite keretse iyo bagize ibinure by'amaraso cyangwa bakorewe ibizamini kubindi mpamvu.

Ibimenyetso ushobora kugira ni ibyo ibinure by'amaraso bishobora gukora kubera Factor V Leiden. Dore ibimenyetso bigaragaza ko ibinure by'amaraso bishobora kuba byarakozwe:

Ibimenyetso bya deep vein thrombosis (DVT) birimo:

• Kubyimbagira mu kaguru kamwe, cyane cyane mu gice cy'ibirenge cyangwa mu mutwe w'ikirenge
• Kubabara cyangwa kubabara mu kaguru kabyimbagira
• Ubushyuhe mu gice cyabyimbagira
• Uruhu rutukura cyangwa rwahindutse ibara ku kaguru
• Amaguru ababara adakira

Ibimenyetso bya Pulmonary embolism birimo:

• Guhumeka nabi k'umugayo
• Kubabara mu gituza bikomeye birushaho kuba bibi iyo uhumeka
• Umutima ukubita cyane
• Gusohora amaraso mu gihe ukoha
• Kumva ugiye kugwa cyangwa utameze neza

Ibi bimenyetso bisaba ubuvuzi bw'ihutirwa kuko ibinure by'amaraso bishobora kuba bibi cyane niba byagiye mu mwijima cyangwa mu zindi ngingo z'ingenzi.

Intandaro ya Factor V Leiden ni iki?

Factor V Leiden iterwa n'impinduka runaka mu mbaraga za gene warazwe mu babyeyi bawe. Iyi mpinduka igira ingaruka kuri gene ikora poroteyine ya Factor V, igira uruhare rukomeye mu mikorere y'amaraso yawe.

Iyi mpinduka ibaho iyo igice kimwe cy'ubwubatsi bwa ADN gihinduka muri gene ya Factor V. Iyi mpinduka ntoya ituma poroteyine ya Factor V irwanya gusenywa na activated protein C, isanzwe ifasha gukumira gukora ibinure byinshi.

Ushobora kuzarwa iyi ndwara mu buryo bubiri. Niba umubyeyi umwe afite iyi mpinduka, ushobora kuzarwa kopi imwe ya gene yahindutse. Niba bombi bayifite, ushobora kuzarwa kopi ebyiri, ibyo bikongera ibyago byo kugira ibinure by'amaraso.

Iyi mpinduka ya gene ishobora kuba yarabayeho imyaka ibihumbi, kandi ishobora kuba yaragize akamaro ku ba sekuruza bacu, ishobora kuba yaragabanyije kuva amaraso mu gihe cyo kubyara cyangwa imvune.

Ni ryari ukwiye kubona muganga kubera Factor V Leiden?

Ukwiye kubona muganga ako kanya niba ufite ibimenyetso by'ibinure by'amaraso, nko kubyimbagira mu kaguru k'umugayo, kubabara mu gituza, cyangwa kugira ikibazo cyo guhumeka. Ibi bimenyetso bisaba isuzuma ry'ubuvuzi bw'ihutirwa utabizi niba ufite Factor V Leiden.

Tegereza kuvugana na muganga wawe ibizamini bya Factor V Leiden niba ufite amateka y'umuryango w'ibinure by'amaraso, cyane cyane niba abavandimwe bawe bagize ibinure bakiri bato cyangwa batagira impamvu isobanutse nko kubagwa cyangwa igihe kirekire badakora.

Ugomba kandi kuvugana na muganga wawe ibizamini niba uteganya gutwita, utekereza gukoresha imiti y'imisemburo, cyangwa witegura kubagwa. Ibi bihe bishobora kongera ibyago byo kugira ibinure by'amaraso niba ufite Factor V Leiden.

Niba umaze kugira ibinure by'amaraso bitasobanuwe, muganga wawe azashaka ko ukorerwa ibizamini by'indwara z'amaraso akora ibinure, harimo Factor V Leiden, kugira ngo amenye ibyago byawe kandi ategure ubuvuzi bukwiye.

Ibyago bya Factor V Leiden ni ibihe?

Ibyago by'ingenzi byo kugira Factor V Leiden ni imiterere y'umuntu. Ushobora kugira iyi ndwara cyane niba ufite inkomoko y'uburayi, cyane cyane niba inkomoko y'umuryango wawe irimo uburayi bw'amajyaruguru, akarere ka Mediterane, cyangwa akarere ka Aziya yo hagati.

Ibintu bimwe na bimwe bishobora kongera ibyago byo kugira ibinure by'amaraso niba ufite Factor V Leiden:

Ibyago by'igihe gito birimo:

• Gutwita n'ibyumweru bitandatu nyuma yo kubyara
• Gukoresha imiti y'ubwirinzi cyangwa imiti y'imisemburo
• Kubagwa, cyane cyane kubagwa amagufwa cyangwa mu nda
• Kudakora igihe kirekire, nko mu rugendo rurerure cyangwa kuryama
• Kugira indwara zimwe na zimwe nka kanseri cyangwa indwara z'uburiganya

Ibyago birambye birimo:

• Kuba ufite imyaka irenga 60
• Kuba ufite umubyibuho ukabije
• Kunywesha itabi
• Kugira izindi ndwara z'amaraso akora ibinure
• Kuba umaze kugira ibinure by'amaraso

Uko ibyago byinshi ufite bifatanije na Factor V Leiden, ni ko amahirwe yo kugira ibinure by'amaraso ari menshi. Muganga wawe ashobora kugufasha kumva urwego rw'ibyago byawe.

Ingaruka zishoboka za Factor V Leiden ni izihe?

Ingaruka nyamukuru ya Factor V Leiden ni ukugira ibinure by'amaraso, bishobora kuva ku bintu bitoroshye kugeza ku bintu bishobora kwica bitewe n'aho bikorwa n'uburyo bivurwa.

Dore ingaruka zikunze kugaragara ushobora guhura nazo:

Deep vein thrombosis (DVT) ni yo ngaruka ikunze kugaragara. Ibi binure bisanzwe bikorwa mu mitsi minini y'amaguru yawe kandi bishobora gutera ububabare, kubyimbagira, no kwangiza imitsi y'amaguru yawe mu gihe kirekire niba bitavuwe vuba.

Pulmonary embolism ibaho iyo ibinure by'amaraso byagiye mu mwijima. Iyi ni ingaruka ikomeye, ishobora kwica, isaba ubuvuzi bw'ihutirwa.

Ingaruka zo gutwita zishobora kuba harimo ibyago byo kubura imbanyi, cyane cyane mu mezi atatu ya nyuma, ndetse n'ingaruka nko guhumeka nabi cyangwa ibibazo by'umwana mu nda.

Ingaruka zidafite akamaro zishobora kuba harimo ibinure by'amaraso mu bice bidasanzwe, nko mu mitsi yo mu nda, mu bwonko, cyangwa mu zindi ngingo. Ibi ni bike ariko bishobora kuba bibi cyane iyo bibaye.

Inkuru nziza ni uko abantu benshi bafite Factor V Leiden batagira ingaruka, kandi abazigira bashobora kubigenzura neza bafashwe neza n'abaganga.

Factor V Leiden ishobora gukumirwa gute?

Ntushobora gukumira Factor V Leiden ubwayo kuko ari indwara y'umuzuko wavukanye. Ariko, ushobora kugabanya cyane ibyago byo kugira ibinure by'amaraso ukora amahitamo meza yo kubaho no gukorana n'itsinda ryawe ry'ubuvuzi.

Dore intambwe ushobora gukora kugira ngo ugabanye ibyago by'ibinure:

Kora imyitozo ngororamubiri ukora imyitozo ngororamubiri buri gihe kandi ukirinda igihe kirekire wicaye cyangwa uhagaze. Ndetse n'imikorere yoroshye nko kugenda cyangwa gukora imyitozo y'amaguru mu gihe cy'ingendo ndende bishobora kugufasha gutuma amaraso yawe akomeza kugenda.

Komeza umubyibuho ukwiye kuko umubyibuho ukabije wongera ibyago by'ibinure by'amaraso. Kurya indyo yuzuye kandi gukora imyitozo ngororamubiri buri gihe bishobora kugufasha kugera ku mubyibuho ukwiye no kuwukomeza.

Ntutabire cyangwa ureke niba utabi ubu. Itabi yongera cyane ibyago by'ibinure by'amaraso, cyane cyane iyo bifatanije na Factor V Leiden.

Vugana na muganga wawe ku gukoresha imisemburo. Imiti y'ubwirinzi n'imiti y'imisemburo ishobora kongera ibyago by'ibinure, bityo ugomba kupima inyungu n'ibyago byayo hamwe na muganga wawe.

Mu bihe by'ibyago byinshi nko kubagwa, gutwita, cyangwa igihe kirekire utakora, muganga wawe ashobora kugutegeka ingamba z'ubwirinzi nko gukoresha imyenda ihambiriye cyangwa imiti igabanya amaraso.

Factor V Leiden imenyekanwa gute?

Factor V Leiden imenyekanwa binyuze mu bipimo by'amaraso bishakisha impinduka mu mbaraga za gene cyangwa bipima uko amaraso yawe asubiza activated protein C. Muganga wawe azakora ibi bipimo niba ufite ibyago cyangwa umaze kugira ibinure by'amaraso.

Isuzuma ryizewe cyane ni isuzuma rya gene rishakisha impinduka ya Factor V Leiden muri ADN yawe. Iri suzuma rishobora kukubwira niba ufite kopi imwe cyangwa ebyiri z'impinduka, ibyo bigira ingaruka ku rwego rw'ibyago byawe.

Ikindi kizamini cyitwa activated protein C resistance test kipima uko amaraso yawe asubiza activated protein C. Niba amaraso yawe adasubiza neza, bigaragaza ko ushobora kugira Factor V Leiden cyangwa izindi ndwara z'amaraso akora ibinure.

Muganga wawe ashobora kandi gukora ibindi bipimo by'amaraso kugira ngo ashake izindi ndwara z'amaraso akora ibinure, kuko abantu rimwe na rimwe bagira indwara nyinshi zongera ibyago byo kugira ibinure by'amaraso.

Ubuvuzi bwa Factor V Leiden ni buhe?

Ubuvuzi bwa Factor V Leiden bugamije gukumira ibinure by'amaraso aho kuvura indwara y'umuzuko ubwayo. Abantu benshi bafite Factor V Leiden ntibakenera ubuvuzi keretse iyo bagize ibinure by'amaraso cyangwa bafite ibyago byinshi.

Niba ufite ibinure by'amaraso, muganga wawe azakwandikira imiti igabanya amaraso, izwi cyane nk'imiti igabanya amaraso. Iyi miti ntigabanya amaraso yawe ariko ifasha gukumira ibinure bishya gukora n'ibinure biriho gukura.

Imiti ikunze gukoreshwa igabanya amaraso irimo:

• Warfarin, isaba gukurikirana amaraso buri gihe
• Imiti yo kunywa igabanya amaraso nka rivaroxaban, apixaban, cyangwa dabigatran
• Injisi za Heparin zo kuvura ako kanya cyangwa iyo imiti yo kunywa idakwiye

Igihe cyo kuvurwa gituruka ku bintu bitandukanye, harimo niba ari ibinure byawe bya mbere, icyabiteye, n'ibyago byawe byose byo kugira ibinure mu gihe kizaza. Bamwe bakenera ubuvuzi bugufi, abandi bashobora gukenera kuvurwa ubuzima bwabo bwose.

Muganga wawe ashobora kandi kugutegeka ubuvuzi bw'ubwirinzi mu bihe by'ibyago byinshi, nko mbere yo kubagwa cyangwa mu gihe cyo gutwita, nubwo utaragira ibinure mbere.

Uko wakwitwara Factor V Leiden murugo

Kwitwara Factor V Leiden murugo bisobanura gukora amahitamo yo kubaho agabanya ibyago byo kugira ibinure by'amaraso mu gihe ukomeza ubuzima bwawe rusange n'imibereho myiza.

Komeza gukora kandi ugenda umunsi wose. Fata ibiruhuko buri gihe uvicaye, cyane cyane mu ngendo ndende z'imodoka cyangwa izindege. Imyitozo yoroshye nko guhaguruka cyangwa gukora imyitozo y'ibirenge bishobora kugufasha gutuma amaraso yawe akomeza kugenda.

Koresha imyenda ihambiriye niba muganga wawe abikugira inama, cyane cyane mu ngendo cyangwa igihe utazaba utakora. Iyi myenda yihariye ifasha kunoza amaraso mu birenge byawe.

Komeza kunywa amazi ahagije, cyane cyane mu ngendo cyangwa mu gihe cy'ubushyuhe. Kutagira amazi ahagije bishobora gutuma amaraso yawe akora cyane kandi bikongera ibyago by'ibinure.

Menya ibimenyetso by'ibinure by'amaraso kandi ushake ubuvuzi bw'ihutirwa niba ufite ibimenyetso nko kubyimbagira mu kaguru k'umugayo, kubabara mu gituza, cyangwa kugira ikibazo cyo guhumeka.

Niba ufashe imiti igabanya amaraso, kurikiza amabwiriza ya muganga wawe neza ku bijyanye n'umwanya wo kuyifata no kuyikurikirana. Komeza urutonde rw'imiti yawe kandi uze ubwira abaganga bose ubwabo uburwayi bwawe bwa Factor V Leiden.

Uko wakwitegura gusura muganga wawe

Kwitwara neza mbere yo gusura muganga wawe bizagufasha kubona igihe cyiza cyo kuvugana na muganga wawe kandi bikwizeze ko uzabona ubuvuzi bwiza kuri Factor V Leiden.

Kora urutonde rw'amateka y'ubuzima bw'umuryango wawe, cyane cyane amakuru yerekeye ibinure by'amaraso, ibicurane, cyangwa indwara z'umutima mu muryango wawe. Andika imyaka ibyo byabayeho n'impamvu zizwi.

Andika imiti yose ufashe ubu, harimo imiti y'amabwiriza y'abaganga, imiti yo kugura udafite amabwiriza y'abaganga, n'ibindi byongerwamo. Imiti imwe ishobora kugira ingaruka ku byago by'ibinure cyangwa ikagira ingaruka ku miti igabanya amaraso.

Andika ibimenyetso byawe niba ufite ibyo, harimo igihe byatangiye, icyabirushaho kuba bibi cyangwa byiza, n'uko bigira ingaruka ku bikorwa byawe bya buri munsi.

Tegura ibibazo byawe mbere. Tegereza kubaza ibyago byawe bwite, niba ukeneye ubuvuzi, impinduka mu mibereho ukwiye gukora, n'igihe ukwiye gushaka ubuvuzi bw'ihutirwa.

Zana umuntu wo mu muryango wawe cyangwa inshuti niba ushaka ubufasha, cyane cyane niba muganira ku bijyanye n'ubuvuzi bugororanye cyangwa niba uhangayikishijwe n'uburwayi bwawe.

Icyo ukwiye kumenya cyane kuri Factor V Leiden

Factor V Leiden ni indwara ikunze kugaragara y'umuzuko yongera ibyago byo kugira ibinure by'amaraso, ariko birashoboka kubigenzura neza ukoresheje uburyo bukwiye n'ubuvuzi. Abantu benshi bafite iyi ndwara babayeho ubuzima busanzwe, bwiza.

Ikintu cy'ingenzi cyo kwibuka ni uko kugira Factor V Leiden ntibivuze ko uzagira ibinure by'amaraso. Ibyago byawe nyabyo biterwa n'ibintu byinshi, harimo imibereho yawe, izindi ndwara, n'imimerere y'ubuzima.

Gukorana na itsinda ryawe ry'ubuvuzi, kumenya neza uburwayi bwawe, no gukora amahitamo meza yo kubaho bishobora kugabanya cyane ibyago by'ingaruka. Nturetse Factor V Leiden iguhagaritse, ariko ubitware uburemere buhagije kugira ngo ufate ibyemezo byiza ku buzima bwawe.

Wibuke ko ubushakashatsi mu by'ubuvuzi bukomeza kunoza ubumenyi bwacu kuri Factor V Leiden no guteza imbere ubuvuzi bwiza. Komeza gufatanya na muganga wawe kugira ngo ugire amabwiriza aheruka yo gucunga uburwayi bwawe.

Ibibazo bikunze kubaho kuri Factor V Leiden

Nshobora guha abana banjye Factor V Leiden?

Yego, Factor V Leiden ni indwara y'umuzuko warazwa ushobora guha abana bawe. Buri mwana afite amahirwe 50% yo kuzarwa iyi ndwara niba umubyeyi umwe ayifite. Niba ababyeyi bombi bafite Factor V Leiden, amahirwe ari menshi, kandi abana bashobora kuzarwa kopi ebyiri z'impinduka, ibyo bikongera ibyago byabo by'ibinure by'amaraso cyane. Inama y'abaganga mu by'umuzuko ishobora kugufasha kumva ibyago byihariye by'umuryango wawe.

Ni byiza gukoresha imiti y'ubwirinzi niba mfite Factor V Leiden?

Imiti y'ubwirinzi ishobora kongera ibyago byo kugira ibinure by'amaraso, kandi ibyo byago biri hejuru niba ufite Factor V Leiden. Ariko, icyemezo si "oya" gusa - biterwa n'ibyago byawe bwite, amateka y'umuryango wawe, niba umaze kugira ibinure mbere. Muganga wawe azapima inyungu n'ibyago neza kandi ashobora kugutegeka ubundi buryo bwo kwirinda cyangwa gukurikirana hafi niba uhisemo imiti y'imisemburo.

Nzagomba gufata imiti igabanya amaraso ubuzima bwanjye bwose?

Oya ntabwo ari ngombwa. Abantu benshi bafite Factor V Leiden ntibakenera imiti igabanya amaraso na gato. Niba ufite ibinure by'amaraso, igihe cyo kuvurwa gituruka ku bintu bitandukanye, harimo icyateye ibinure, niba ari ibyawe bya mbere, n'ibyago byawe byose byo kugira ibinure mu gihe kizaza. Bamwe bakenera ubuvuzi iminsi mike, abandi bashobora gukenera kuvurwa igihe kirekire. Muganga wawe azakomeza gusuzuma niba ukeneye kuvurwa.

Nshobora gukora imyitozo ngororamubiri nk'uko bisanzwe niba mfite Factor V Leiden?

Yego, imyitozo ngororamubiri isanzwe ifitiye akamaro kandi irakenewe ku bantu bafite Factor V Leiden. Imyitozo ngororamubiri ifasha kunoza amaraso kandi ishobora kugabanya ibyago byo kugira ibinure by'amaraso. Ntukwiye kwirinda imyitozo runaka keretse niba ufashe imiti igabanya amaraso, muri ubwo buryo muganga wawe ashobora kugutegeka kwirinda imikino ishobora gutera imvune.

Ndagomba gukora iki niba nteganya kubagwa?

Menyesha itsinda ry'abaganga bakubaga uburwayi bwawe bwa Factor V Leiden mbere y'igihe cyo kubagwa. Kubagwa byongera ibyago by'ibinure by'amaraso kuri buri wese, kandi ibyo byago biri hejuru niba ufite Factor V Leiden. Abaganga bawe bashobora kugutegeka ingamba z'ubwirinzi nko gufata imiti igabanya amaraso, imyenda ihambiriye, cyangwa gukora vuba nyuma yo kubagwa. Uburyo bwihariye buzaba biterwa n'ubwoko bw'ubuvuzi n'ibyago byawe bwite. Ntuzigere urekura iki kiganiro - ni ingenzi ku buzima bwawe.