Mgus

Monoclonal gammopathy idafite ishingiro (MGUS) ni uburwayi aho umwimerere utari mwiza w’amaprotéine uboneka mu maraso. Iyo protéine yitwa protéine ya monoclonal cyangwa protéine M.

Iyo protéine ikorwa mu mubiri woroha, ukora amaraso, uri hagati mu gufata amagufwa. Uwo mubiri ukora amaraso ni ubwonko bw’amagufwa. Monoclonal gammopathy idafite ishingiro iba kenshi mu bagabo bakuze.

MGUS isanzwe nta kibazo itera. Ariko rimwe na rimwe ishobora gutera indwara zikomeye. Izo ndwara zirimo zimwe mu ndwara za kanseri yamaraso.

Abantu bafite umwimerere munini w’iyo protéine mu maraso bagomba gukorerwa isuzuma buri gihe. Ni ukugira ngo bahabwe ubuvuzi hakiri kare iyo iyi ndwara ikomeye. Niba idakomeye, MGUS ntiisaba ubuvuzi.

Abantu bafite monoclonal gammopathy akenshi nta bimenyetso bagira. Bamwe bagira ibibyimba cyangwa ibibazo by'imiterere y'imyakura, nko kubabara cyangwa kunanirwa. Ibizamini by'amaraso byakozwe kubindi bibazo bishobora kubona MGUS ku bw'amahirwe.

Impuguke ntizizi icyateza MGUS. Impinduka mu mimerere y'impyiko no kuba hafi y'ibintu bimwe na bimwe bya chimique, nka biriya bikoresha mu kwica ibyonnyi, bigaragara ko bigira uruhare.

Ibintu byongera ibyago byo kwibasirwa na MGUS birimo:

• Imyaka. Umuntu ubonerwa iyi ndwara afite imyaka 70 y'amavuko muri rusange.
• Ubwoko. Abanyafurika n'Abanyamerika b'Abirabura bafite ibyago byinshi byo kwibasirwa na MGUS ugereranyije n'abazungu.
• Ibitsina. MGUS igaragara cyane mu bagabo.
• Amateka y'umuryango. Kugira abagize umuryango bafite MGUS bishobora kongera ibyago.

Buri mwaka, abantu bagera kuri 1% bafite MGUS barwara kanseri zimwe na zimwe z'amaraso cyangwa izindi ndwara zikomeye, nka:

• Multiple myeloma.
• Light chain amyloidosis.
• Waldenstrom macroglobulinemia.
• Lymphoma.

Ibindi bibazo bifitanye isano na MGUS birimo amagufa akunze kuvunika, ibibyimba by'amaraso, ibibazo by'impyiko, n'ubuhangange bw'imitsi yo hanze y'ubwonko n'umugongo, bizwi kandi nka peripheral neuropathy.

Kuko MGUS isanzwe nta bimenyetso itera, abantu bayirwaye bakunze kubimenya ku bw’impanuka mu bipimo by’amaraso byakozwe ku mpamvu zindi. Nyuma yaho, ibindi bipimo bishobora kuba birimo: Ibindi bipimo by’amaraso. Ibi bishobora gufasha gukuraho izindi mpamvu z’ikigero cy’imyonangongo kiri hejuru. Kandi bishobora kugenzura kwangirika kw’impyiko. Ibizamini by’inkari. Ibipimo by’inkari bifatwa mu masaha 24 bishobora gufasha kumenya niba imyonangongo idasanzwe iri mu nkari. Nanone bishobora kugenzura kwangirika kw’impyiko. Ibizamini by’amashusho. Ku bantu bafite ububabare bw’amagufa, MRI cyangwa positron emission tomography (PET) scan bishobora gushaka ibibazo by’amagufa bituruka kuri MGUS. Nanone bashobora kuba bakeneye ikizamini cyo gupima uburemere bw’amagufa, bizwi kandi nka bone density. Ikizamini cy’amasogwe y’amagufa. Igikombe cy’ubushyuhe gikuramo igice cy’amasogwe y’amagufa inyuma y’imwe mu magufwa y’ikibero kugira ngo gisuzuzwe. Ibi bisanzwe bikorerwa abantu bafite ibyago byo kurwara indwara ikomeye cyangwa ibindi bibazo bifitanye isano na MGUS. Kwitabwaho muri Mayo Clinic Itsinda ryacu ryita ku barwayi ry’inzobere za Mayo Clinic rishobora kugufasha mu bibazo byawe by’ubuzima bifitanye isano na Monoclonal gammopathy of undetermined significance (MGUS) Tangira hano Amakuru y’inyongera Monoclonal gammopathy of undetermined significance (MGUS) kwitabwaho muri Mayo Clinic Biopsy y’amasogwe y’amagufa Igipimo cyuzuye cy’amaraso (CBC) Ikizamini cya Creatinine X-ray Garagaza amakuru afitanye isano menshi

MGUS ntabwo isaba kuvurwa. Ariko umuvuzi wawe arashobora kugusaba gukora isuzuma buri gihe kugira ngo akurikirane uko iyi ndwara imeze. Ibizamini bishobora gutangira nyuma y'amezi atandatu ubonye indwara. Gutegereza no gukurikirana Ku barwaye MGUS bafite ibyago byinshi byo kurwara indwara ikomeye, gukora isuzuma kenshi bishobora gukurikirana indwara. Ubwo buryo, kuvura bishobora gutangira vuba bishoboka niba bibaye ngombwa. Ibimenyetso byo kwitondera birimo: Kubabara amagufa. Kwumva unaniwe cyangwa intege nke. Kugabanya ibiro utabishaka. Urufuriro cyangwa ibinya mu ijoro. Kubabara umutwe, guhindagurika, kubabara imiyoboro y'imbere, cyangwa guhinduka mu maso cyangwa mu matwi. Kuzana amaraso. Kugira ubusembwa bw'amaraso cyangwa ibindi bintu bidafashe mu maraso. Umuhogo w'ingingo, umwijima cyangwa umwijima. Imiti Imiti yo kurwanya indwara y'amagufa izwi nka osteoporosis yongera uburemere bw'amagufa. Urugero harimo alendronate (Fosamax), risedronate (Actonel, Atelvia), ibandronate na zoledronic acid (Reclast, Zometa). Saba gahunda yo kubonana na muganga