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Ibibyimba Bya Pituitary

Incamake

Umuhengeri w'umusemburo ni ibintu bidasanzwe bikura mu gice cy'umusemburo. Uyu musemburo ni umubiri ufite ubunini bungana n'icyatsi. Uherereye inyuma y'izuru ku ruhande rw'ubwonko. Bimwe muri ibi bintu bituma umusemburo ukora byinshi by'imisemburo runaka igenzura imikorere y'umubiri. Ibindi bishobora gutuma umusemburo ukora bike by'iyo misemburo.

Umuhengeri w'umusemburo ubanza kuba utari kanseri. Ibyo bivuze ko atari kanseri. Irindi zina ry'ibi bintu bitari kanseri ni adenomas y'umusemburo. Adenomas nyinshi ziguma mu gice cy'umusemburo cyangwa mu mubiri uri hafi yaho, kandi zikura buhoro buhoro. Ntibisanzwe ko zikwirakwira mu bindi bice by'umubiri.

Umuhengeri w'umusemburo ushobora kuvurwa mu buryo butandukanye. Umuhengeri ushobora gukurwaho n'ubuganga. Cyangwa uburyo bwo gukura bwakongererwa imiti cyangwa imirasire. Rimwe na rimwe, urwego rw'imisemburo rugenzurwa n'imiti. Umuganga wawe ashobora kugutekerezaho guhuza ubwo buryo bwo kuvura. Mu bihe bimwe na bimwe, kureba - bizwi kandi nka 'gategereza no kubona' - bishobora kuba amahitamo meza.

Ubwoko bw'adenomas y'umusemburo harimo:

  • Ikorera. Izi adenomas zikora imisemburo. Zituma ibimenyetso bitandukanye bitewe n'ubwoko bw'imisemburo zikora. Adenomas y'umusemburo ikora igabanuka mu byiciro bitandukanye, harimo ibyakozwe na:
    • Hormone ya Adrenocorticotropic. Iyi hormone izwi kandi nka ACTH. Ibi bintu rimwe na rimwe byitwa corticotroph adenomas.
    • Hormone yo gukura. Ibi bintu byitwa somatotroph adenomas.
    • Hormone ya Luteinizing na hormone yo gukurura follicle. Izi hormone izwi kandi nka gonadotropins. Umuhengeri w'umusemburo ukora izi hormone witwa gonadotroph adenomas.
    • Prolactin. Ibi bintu byitwa prolactinomas cyangwa lactotroph adenomas.
    • Hormone istimula thyroid. Ibi bintu byitwa thyrotroph adenomas.
  • Hormone ya Adrenocorticotropic. Iyi hormone izwi kandi nka ACTH. Ibi bintu rimwe na rimwe byitwa corticotroph adenomas.
  • Hormone yo gukura. Ibi bintu byitwa somatotroph adenomas.
  • Hormone ya Luteinizing na hormone yo gukurura follicle. Izi hormone izwi kandi nka gonadotropins. Umuhengeri w'umusemburo ukora izi hormone witwa gonadotroph adenomas.
  • Prolactin. Ibi bintu byitwa prolactinomas cyangwa lactotroph adenomas.
  • Hormone istimula thyroid. Ibi bintu byitwa thyrotroph adenomas.
  • Macroadenomas. Izi ni adenomas nini. Zipima hafi santimetero 1 cyangwa birenga. Ibyo ni bike kurusha igice cy'igice cya kabiri. Zishobora gukora cyangwa kutakora.
  • Microadenomas. Izi adenomas ni nto. Zipima munsi ya santimetero 1. Ibyo ni bike kurusha igice cy'igice cya kabiri. Zishobora gukora cyangwa kutakora.
  • Hormone ya Adrenocorticotropic. Iyi hormone izwi kandi nka ACTH. Ibi bintu rimwe na rimwe byitwa corticotroph adenomas.
  • Hormone yo gukura. Ibi bintu byitwa somatotroph adenomas.
  • Hormone ya Luteinizing na hormone yo gukurura follicle. Izi hormone izwi kandi nka gonadotropins. Umuhengeri w'umusemburo ukora izi hormone witwa gonadotroph adenomas.
  • Prolactin. Ibi bintu byitwa prolactinomas cyangwa lactotroph adenomas.
  • Hormone istimula thyroid. Ibi bintu byitwa thyrotroph adenomas.

Umuhengeri w'umusemburo utandukanye n'icyitwa umusemburo. Umuhengeri ni umufuka ushobora kuzura umwuka, amazi cyangwa ibindi bintu. Umuhengeri ni ikintu kitari gisanzwe cy'uturemangingo gishobora gukura igihe kinini. Umuhengeri ushobora gukura kuri cyangwa hafi y'umusemburo, ariko si umuhengeri cyangwa adenoma.

Ibimenyetso

Pituitary tumors, growths in the pituitary gland, don't always cause problems. Sometimes, they're found during medical tests like MRIs or CT scans done for other reasons. If they don't cause symptoms, they usually don't need treatment.

How Pituitary Tumors Cause Symptoms:

Pituitary tumors can cause symptoms in several ways:

  • Pressure: The tumor can press on the brain or nearby tissues and nerves, leading to various problems.
  • Hormone Imbalance: The pituitary gland controls many hormones in the body. A tumor can either produce too much of one or more hormones, or disrupt the gland's function, causing too little of certain hormones.

Symptoms of Pituitary Tumors:

Symptoms can vary greatly depending on the type of tumor and the hormones involved. Here are some common signs:

  • General Pressure Symptoms: Headaches, eye problems (like vision loss, double vision), facial pain (including sinus or ear pain), drooping eyelids, and seizures.

  • Hormone-Related Symptoms: These symptoms vary based on which hormones are affected.

    • Too Much Hormone: Symptoms could include tiredness, lack of energy, sexual problems (erections, libido), changes in menstrual cycles, nausea, feeling cold, unintended weight loss or gain. These excess hormones can also lead to specific conditions.

    • Too Little Hormone: If the tumor disrupts the pituitary gland's ability to produce hormones, symptoms may include the same hormone-related issues as above, but in the opposite direction.

Types of Pituitary Tumors and Their Symptoms:

Different types of pituitary tumors produce different hormones, leading to unique symptoms:

  • Cushing Disease: Caused by a tumor producing too much adrenocorticotropic hormone (ACTH). This leads to high cortisol levels, resulting in:

    • Weight gain, especially around the midsection and upper back
    • Round face
    • Stretch marks
    • Thin, easily bruised skin
    • Thin arms and legs, muscle weakness
    • Thicker body hair
    • Slow healing wounds
    • Darkened skin patches
    • Acne
    • Changes in menstrual cycles
    • Sexual problems

  • Acromegaly: Caused by a tumor producing too much growth hormone. Symptoms include:

    • Changes in facial features (larger lips, nose, tongue, longer jaw, wider spaces between teeth)
    • Enlarged hands and feet
    • Thicker skin
    • Increased sweating and body odor
    • Joint pain
    • Deeper voice
    • In children/teens, faster growth, becoming unusually tall (gigantism).

  • Gonadotroph Adenomas: Produce luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Usually, symptoms are from the tumor's pressure on nearby tissues rather than excess hormones. Symptoms may differ between men and women:

    • Women: Changes in menstrual cycles, fertility problems, ovarian enlargement and pain (ovarian hyperstimulation syndrome).
    • Men: Enlarged testicles, higher testosterone levels.

  • Prolactinomas: These tumors produce too much prolactin, affecting sex hormones (estrogen and testosterone).

    • Women: Irregular or absent menstrual periods, milky breast discharge, breast tenderness, fertility problems, decreased libido.
    • Men: Erection problems, decreased libido, breast growth, fertility problems, decreased body and facial hair.

  • Thyrotroph Adenomas: Produce thyroid-stimulating hormone (TSH), causing the thyroid to produce too much thyroxine (T4). This leads to hyperthyroidism (overactive thyroid):

    • Weight loss
    • Rapid or irregular heartbeat
    • Nervousness, anxiety, or irritability
    • Frequent bowel movements
    • Sweating
    • Tremors
    • Sleep problems

Important Considerations:

  • Hereditary Pituitary Tumors: Some pituitary tumors are inherited, particularly in families with multiple endocrine neoplasia type 1 (MEN 1). If you have a family history of MEN 1, talk to your doctor about testing for pituitary tumors.

When to See a Doctor:

If you experience any symptoms that might be related to a pituitary tumor, it's crucial to see your healthcare provider. Early diagnosis and treatment can help manage hormone levels and reduce symptoms.

Igihe cyo kubona umuganga

Niba ugize ibimenyetso bishobora kuba bifitanye isano n'ubwandu bwa pituitary, reba umuvuzi wawe. Ubuvuzi bw'ubwandu bwa pituitary bushobora kugarura imisemburo ku rwego rwiza kandi bugatuma ibimenyetso bigabanuka. Nubwo ari bito, bimwe mu bwandu bwa pituitary birakomoka ku miryango. Bisobanura ko bihererekanywa mu miryango. By'umwihariko, indwara ikomoka ku miryango y'ibice byinshi by'imisemburo, ubwoko bwa 1 (MEN 1) ishobora gutera ubu bwandu bwa pituitary. Niba MEN 1 iri mu muryango wawe, vugana n'umuvuzi wawe ku bipimo bishobora kugufasha kubona ubu bwandu bwa pituitary hakiri kare. Kanda hano ubone amakuru mashya ku kuvura, ibizamini n'abaganga babaga indwara z'ubwonko.

Impamvu

Umuhini (glande pituitaire) ni umusemburo muto ufite ubunini nk'ubw'ikaramu. Uherereye inyuma y'izuru hasi y'ubwonko. Nubwo ari muto, umuhini ugira ingaruka kuri buri gice cy'umubiri. Imihini ikora igenzura imikorere y'ingenzi y'umubiri, nko gukura, umuvuduko w'amaraso no kubyara. Impamvu y'ukudakora neza kw'ingirabuzimafatizo mu muhini, bigatera uburibwe, ntibiramenyekana. Mu bihe bitoroshye, uburibwe bw'umuhini bushobora guterwa na gene wavutse uzanye. Ariko abenshi nta mpamvu isobanutse y'amasoko. Nyamara, abahanga mu bya siyansi batekereza ko impinduka za gene zishobora kugira uruhare mu mikurire y'uburibwe bw'umuhini.

Ingaruka zishobora guteza

Abantu benshi bafite uburibwe bwa pituitary nta bintu bibatera ibyago byinshi byo kurwara izi tumors. Ibintu by'ibidukikije n'imibereho asa nkaho nta cyo bikora ku kaga umuntu afite cyo kurwara uburibwe bwa pituitary.

Nubwo ibintu by'umurage bisa nkaho bigira uruhare, abantu benshi bafite uburibwe bwa pituitary nta mateka yabyo mu muryango wabo.

Ibyago byonyine bizwi ni ibintu bike cyane by'umurage byongera ibyago byinshi by'ibibazo by'ubuzima, birimo uburibwe bwa pituitary. Ibi bintu birimo:

  • Indwara nyinshi zikura mu mubiri, ubwoko bwa 1, bizwi kandi nka MEN 1.
  • Indwara nyinshi zikura mu mubiri, ubwoko bwa 4, bizwi kandi nka MEN 4.
  • Carney complex.
  • McCune-Albright syndrome.
Ingaruka

Ubusanzwe, ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo (pituitary gland) ntibikwirakwira mu bindi bice by'umubiri. Ariko bishobora kugira ingaruka ku buzima bw'umuntu. Ibibyimba byo muri iki gice bishobora gutera:

  • Ibibazo by'ububone, birimo no kubura ubwenge.
  • Isuri y'amaraso.
  • Kubura amagufwa.
  • Ibibazo by'umutima.
  • Ibibazo byo gutekereza no kwibuka.

Kugira ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo, cyangwa kubikuramo hakoreshejwe ubuvuzi, bishobora guhindura burundu imisemburo umubiri wawe ukora. Kubera iyo mpamvu, ushobora gukenera imiti isubiza imisemburo mu mubiri wawe ubuzima bwawe bwose.

Ingaruka mbi z'ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo, gake ariko zishobora kuba zikomeye, ni ukubura amaraso muri iki gice (pituitary apoplexy). Ibi bibaho iyo amaraso azamutse mu kibyimba giturumbuka. Ibimenyetso birimo:

  • Uburwayi bukabije bw'umutwe, bushobora kuba bubi kurusha ibindi byose wari warigeze kugira.
  • Ibibazo by'ububone, birimo kubona ibintu bibiri cyangwa kubura ubwenge mu jisho rimwe cyangwa mu yombi.
  • Isesemi no kuruka.
  • Gusinzira cyangwa ibindi bibazo byo gutekereza.

Pituitary apoplexy isaba ubuvuzi bwihuse. Ubuvuzi busanzwe burimo gufata imiti ya corticosteroid kugira ngo hagaruke kubyimba hafi y'ikibyimba. Ushobora kandi gukenera kubagwa kugira ngo ukureho ikibyimba.

Kupima

Umuntu akenshi ntabwo amenya cyangwa ngo amenye ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo (pituitary gland). Mu bihe byinshi, ni ukubera ko ibimenyetso biterwa n'ibibyimba byo muri iki gice bikora imisemburo, bizwi nka adenomas zikora, n'ibibyimba binini, bizwi nka macroadenomas, bisa n'ibimenyetso by'izindi ndwara. Nanone ni ukubera ko bikura buhoro buhoro mu gihe. Ibibyimba bito byo mu gice cy'ubwonko gishinzwe gukora imisemburo, bita nonfunctioning microadenomas, akenshi ntibitera ibimenyetso. Niba byagaragaye, ni ukubera ko babikoze mu bipimo byo kubona ishusho y'umubiri, nka MRI cyangwa CT scan, byakozwe ku rundi mpamvu.

Kugira ngo hamenyekane kandi hamenywe ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo, umuganga wawe ashobora kukuganiraho amateka yawe n'ay'umuryango wawe, akakora n'isuzuma rusange. Ibizamini byo kumenya ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo bishobora kandi kuba birimo:

  • Ibizamini by'amaraso. Ibizamini by'amaraso bishobora kwerekana niba umubiri wawe ufite imisemburo myinshi cyangwa micye. Kuri imwe muri iyo misemburo, ibisubizo by'ibizamini by'amaraso byerekana ko hari imisemburo myinshi bishobora kuba ari byo byose umuganga wawe akeneye kugira ngo amenye adenoma yo mu gice cy'ubwonko gishinzwe gukora imisemburo.

Kuri izindi misemburo, nka cortisol, igisubizo cy'ikizamini cy'amaraso kigaragaza ko hari imisemburo myinshi bishobora gukurikirwa n'ibindi bizamini. Ibyo bizamini bishobora kwerekana niba igisubizo cyabanje cyatewe na adenoma yo mu gice cy'ubwonko gishinzwe gukora imisemburo cyangwa n'ikibazo cy'ubuzima.

Ibisubizo byerekana ko urwego rw'imisemburo ruri hasi bigomba gukurikirwa n'ibindi bizamini, akenshi ni ibizamini byo kubona ishusho y'umubiri, kugira ngo harebwe niba adenoma yo mu gice cy'ubwonko gishinzwe gukora imisemburo ishobora kuba ari yo yateye ibyo bisubizo.

  • Ibizamini by'inkari. Ikizamini cy'inkari gishobora gukoreshwa mu gufasha kumenya adenoma yo mu gice cy'ubwonko gishinzwe gukora imisemburo ikora imisemburo myinshi ya ACTH. ACTH nyinshi itera cortisol nyinshi mu mubiri kandi itera indwara ya Cushing.
  • MRI scan. MRI scan ni ikizamini gikoreshwa mu kubona ishusho y'imbere mu mubiri hakoreshejwe uburyo bwa magnétike n'amashusho akorwa na mudasobwa. MRI y'ubwonko ishobora gufasha kumenya ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo no kwerekana aho biherereye n'ubunini bwabyo.
  • CT scan. CT scan ni uburyo bwo kubona ishusho y'imbere mu mubiri bukoresha uburyo bwa X-rays. MRI scans ikoreshwa kenshi kurusha CT scans mu kumenya no kuvura ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo. Ariko CT scan ishobora gufasha gutegura kubaga niba umuganga wawe akubwiye ko igomba gukurwaho.
  • Ibizamini by'amaso. Ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo bishobora kugira ingaruka ku kubona, cyane cyane kubona ku ruhande, bizwi nka peripheral vision. Gusuzuma amaso yawe kugira ngo urebe uko ubona neza bishobora gufasha umuganga wawe gufata umwanzuro w'ibindi bizamini bishobora kuba bikenewe kugira ngo hamenyekane ibibyimba byo mu gice cy'ubwonko gishinzwe gukora imisemburo.

Ibizamini by'amaraso. Ibizamini by'amaraso bishobora kwerekana niba umubiri wawe ufite imisemburo myinshi cyangwa micye. Kuri imwe muri iyo misemburo, ibisubizo by'ibizamini by'amaraso byerekana ko hari imisemburo myinshi bishobora kuba ari byo byose umuganga wawe akeneye kugira ngo amenye adenoma yo mu gice cy'ubwonko gishinzwe gukora imisemburo.

Kuri izindi misemburo, nka cortisol, igisubizo cy'ikizamini cy'amaraso kigaragaza ko hari imisemburo myinshi bishobora gukurikirwa n'ibindi bizamini. Ibyo bizamini bishobora kwerekana niba igisubizo cyabanje cyatewe na adenoma yo mu gice cy'ubwonko gishinzwe gukora imisemburo cyangwa n'ikibazo cy'ubuzima.

Ibisubizo byerekana ko urwego rw'imisemburo ruri hasi bigomba gukurikirwa n'ibindi bizamini, akenshi ni ibizamini byo kubona ishusho y'umubiri, kugira ngo harebwe niba adenoma yo mu gice cy'ubwonko gishinzwe gukora imisemburo ishobora kuba ari yo yateye ibyo bisubizo.

Umuganga wawe ashobora kukwerekeza ku muhanga mu ndwara z'imisemburo, bizwi nka endocrinologist, kugira ngo akore ibindi bizamini.

Uburyo bwo kuvura

Ama-adenoma menshi atari menshi menshi ntabwo akenera kuvurwa. Si kanseri, bityo niba adatera ibimenyetso, gukurikirana gusa igihe kirekire bishobora kuba uburyo bwiza. Niba kuvurwa bikenewe, kuvurwa byihariye biterwa no kureba ubwoko bw'ibibyimba, ubunini, aho biherereye n'ukuntu bikura igihe kirekire. Niba igituntu giterwa no kuba hari imisemburo myinshi cyangwa mike cyane mu mubiri, ibyo na byo bigira ingaruka ku ivurwa. Imyaka yawe n'ubuzima bwawe muri rusange bigira uruhare mu gutegura ivurwa. Intego y'ivurwa ni ukugira ngo: Gusubiza urwego rw'imisemburo ku rwego rwiza. Kwirinda ibindi byangiza kuri gland ya pituitary no gusubiza imikorere isanzwe. Gusubiza ibimenyetso byatewe n'umuvuduko w'igituntu cyangwa kubabuza kuba bibi. Niba adenoma ya pituitary ikenera kuvurwa, ishobora kuba irimo kubaga kugira ngo hakureho igituntu. Imiti cyangwa ubuvuzi bwa radiation na byo bishobora gukoreshwa mu kuvura adenoma ya pituitary. Kuvura bikubiyemo itsinda ry'inzobere mu by'ubuvuzi. Iyo kipe ishobora kuba irimo: Umuganga w'ubwonko, witwa neurosurgeon. Umuganga w'izuru n'ibitotsi, witwa umuganga wa ENT. Inzobere mu ndwara z'imisemburo, witwa endocrinologist. Inzobere mu buvuzi bwa radiation, witwa radiation oncologist. Kubaga Kubaga kuvura igituntu cya pituitary bikubiyemo gukuraho igituntu. Ibi rimwe na rimwe bita tumor resection. Umuganga ashobora kugutekerezaho kubaga niba adenoma ya pituitary: Itera igitutu ku mitsi y'amaso ikagabanya ubushobozi bwo kubona. Itera ibindi bimenyetso, nko kubabara umutwe cyangwa mu maso. Igabanya urwego rw'imisemburo mu mubiri kubera igitutu kuri gland ya pituitary. Itera umubiri gukora imisemburo myinshi. Ibintu bikurikira kubaga bisanzwe biterwa n'ubwoko bwa adenoma, ubunini n'aho biherereye, niba igituntu cyaraguye mu ngingo zikikikije. Kubaga kugira ngo bakureho igituntu cya pituitary birimo kubaga endoscopic transnasal transsphenoidal na craniotomy. Kubaga endoscopic transnasal transsphenoidal Agasanduku k'ishusho fungura Kubaga endoscopic transnasal transsphenoidal Kubaga endoscopic transnasal transsphenoidal Mu kubaga endoscopic transnasal transsphenoidal, igikoresho cy'abaganga gishyirwa mu cyuho cy'izuru ndetse no ku ruhande rw'ikibuno cy'izuru kugira ngo hagerwe ku gicurane cya pituitary. Ubu buvuzi na bwo bwitwa adenomectomy. Ni bwo buvuzi busanzwe bukoreshwa mu gukuraho adenoma ya pituitary. Mu gihe cy'ubuvuzi, umuganga — akenshi neurosurgeon ufatanyije n'umuganga w'izuru n'ibitotsi — akuraho adenoma binyuze mu izuru n'ibitotsi. Ubu buvuzi ntibukenera igikomere cyo hanze, bita incision. Ntibugira ingaruka ku bindi bice by'ubwonko. Ubu buvuzi ntibutera inkovu ushobora kubona. Macroadenomas nini bishobora kuba bigoye gukuraho muri ubu buvuzi. Ibyo ni byo cyane cyane niba macroadenoma yaragwiriye imiyoboro y'amaraso, imiyoboro y'amaraso cyangwa ibindi bice by'ubwonko. Kubaga transcranial Ubu buvuzi na bwo bwitwa craniotomy. Bukoresha bike ugereranije na kubaga endoscopic transnasal transsphenoidal ku bitunguru bya pituitary. Ubu buvuzi butuma byoroshye kugera no gukuraho macroadenomas nini cyangwa ibintu bya pituitary byaraguye ku mitsi cyangwa mu ngingo z'ubwonko. Byongera byoroshya umuganga kubona aho igituntu kigeze, ndetse n'ibice by'ubwonko bikikikije. Mu gihe cy'ubuvuzi bwa transcranial, umuganga akuraho igituntu binyuze mu gice cyo hejuru cy'umutwe binyuze mu gikomere mu ruhu. Kubaga endoscopic transnasal transsphenoidal na kubaga transcranial ni uburyo butekanye muri rusange. Ingaruka mbi ni nke. Ariko nk'uko biri mu buvuzi ubwo aribwo bwose, hari ibyago. Ingaruka mbi nyuma yo kubaga igituntu cya pituitary zishobora kuba: Gukura amaraso. Kwandura. Kugira reaction ku muti ugutera ibitotsi mu gihe cy'ubuvuzi Icyo gisebo cyitwa anesthesia. Kubabara umutwe by'igihe gito no gufunga izuru. Kugira ikibazo cy'ubwonko. Kubona ibintu bibiri cyangwa kubura ubushobozi bwo kubona. Kwibasira gland ya pituitary. Diabetes insipidus Kubaga kugira ngo bakureho igituntu cya pituitary bishobora kwangiza gland ya pituitary. Ibyo bishobora kugabanya ubushobozi bwo gukora imisemburo, bigatuma haba ibindi bibazo by'ubuzima birimo diabetes insipidus. Iyi ndwara ibaho iyo gland ya pituitary idashobora gukora imisemburo ihagije ya vasopressin. Iyo hormone ikorwa inyuma ya gland, ahantu hitwa posterior pituitary. Diabetes insipidus itera amazi y'umubiri kuba adahwitse, ibyo bigatuma umubiri ukora inkari nyinshi. Ibyo bishobora gutera inyota ikabije no kongera ibyago byo gukama. Diabetes insipidus nyuma yo kubaga kugira ngo bakureho igituntu cya pituitary isanzwe iba igihe gito. Isanzwe iracika ubuvuzi butabayeho mu minsi mike. Niba diabetes insipidus imara igihe kirekire kurusha ibyo, kuvurwa hamwe n'uburyo bwakozwe bwa vasopressin bishobora gukoreshwa. Iyi ndwara ikunda gucika nyuma y'ibyumweru cyangwa amezi. Niba umuvuzi wawe agutekerezaho kubaga kugira ngo uvurwe igituntu cya pituitary, baza ku bijyanye n'ubuvuzi bukubereye. Muganire ku ngaruka mbi zishoboka, ibyago n'ingaruka mbi. Baza icyo ushobora kwitega mu gihe cyo gukira. Ubuvuzi bwa radiation Ubuvuzi bwa radiation bukoresha ibintu bifite ingufu nyinshi bya radiation mu kuvura ibintu bya pituitary. Ubuvuzi bwa radiation bushobora gukoreshwa nyuma yo kubaga. Cyangwa bushobora gukoreshwa bwonyine niba kubaga atari amahitamo. Ubuvuzi bwa radiation bushobora gufasha niba igituntu cya pituitary: Kitakuweho burundu hamwe no kubaga. Kigarutse nyuma yo kubaga. Gitera ibimenyetso imiti idakemura. Intego y'ubuvuzi bwa radiation kuri adenomas ya pituitary ni ugucunga ukurura kwa adenoma cyangwa guhagarika adenoma gukora imisemburo. Uburyo bw'ubuvuzi bwa radiation bushobora gukoreshwa mu kuvura ibintu bya pituitary birimo: Stereotactic radiosurgery. Akenshi bitangwa nk'umwanya umwe ukomeye, ubu bwoko bw'ubuvuzi bwa radiation buhererekanya neza ibintu bya radiation ku gicurane. Nubwo ijambo "kubaga" riri mu izina ryacyo, nta gikomere mu ruhu gikenewe. Bitanga ibintu bya radiation ubunini n'isura y'igituntu mu gicurane bifashishije ubuhanga bwo kubona ubwonko. Ibi bisaba gushyira umufuka w'umutwe ku mutwe. Uwo mufuka ukurwaho nyuma yo kuvurwa. Radiation mike ihura n'ingingo zikomeye hafi y'igituntu. Ibyo bigabanya ibyago byo kwangiza ingingo zikomeye. External beam radiation. Ubu buryo na bwo bwitwa fractionated radiation therapy. Butanga radiation mu bice bito igihe kirekire. Icyiciro cy'ubuvuzi gisanzwe gikorerwa gatanu mu cyumweru ibyumweru 4 kugeza ku 6. Intensity modulated radiation therapy. Ubu bwoko bw'ubuvuzi bwa radiation, bwitwa IMRT, bukoresha mudasobwa ibemerera gushyira ibintu mu buryo bwo gukikiza igituntu kuva mu mpande nyinshi. Imbaraga z'ibintu zishobora kugabanuka. Ibyo bigabanya ibyago by'ingaruka mbi ku ngingo zikomeye. Proton beam therapy. Ikindi kintu cya radiation, proton beam therapy ikoresha ions zizigamye, bita protons, kugira ngo zigere ku bitunguru. Ibintu bya proton bihagarara nyuma yo kurekura ingufu zabo mu gicurane. Ibi bivuze ko ibintu bishobora kugenzurwa kugira ngo bigere kuri adenoma ya pituitary n'ibyago bike by'ingaruka mbi ku ngingo zikomeye. Ubu bwoko bw'ubuvuzi bwa radiation bukenera ibikoresho bidasanzwe. Ntabwo buraboneka hose. Ingaruka mbi zishoboka n'ingaruka mbi z'ubuvuzi bwa radiation kuri adenomas ya pituitary zishobora kuba: Kwibasira gland ya pituitary bigabanya ubushobozi bwayo bwo gukora imisemburo. Kwibasira ingingo zikomeye hafi ya gland ya pituitary. Impinduka zo kubona kubera kwangiza imiyoboro y'amaso. Kwibasira ibindi mitsi hafi ya gland ya pituitary. Ibyago bike byo kurwara igituntu cy'ubwonko. Radiation oncologist asuzuma uko uhagaze akaganirira nawe ku byiza n'ibyago by'ubuvuzi bwa radiation mu mimerere yawe. Bisanzwe bimamara amezi kugeza ku myaka kugira ngo ubone inyungu nyinshi z'ubuvuzi bwa radiation kuri adenomas ya pituitary. Ingaruka mbi n'ingaruka mbi z'ubuvuzi bwa radiation ntizisanzwe zigaragara ako kanya. Ni ngombwa kugira ubuvuzi bwo gukurikirana igihe kirekire kugira ngo hamenyekane ibibazo by'imisemburo bishobora kubaho kubera ubuvuzi bwa radiation. Imiti Kuvurwa hamwe n'imiti bishobora kuba byiza mu gucunga adenomas ya pituitary. Bishobora gufasha kugabanya umubare w'imisemburo umubiri ukora kubera igituntu. Imiti imwe na imwe ishobora kugabanya ubwoko bumwe bw'ibintu bya pituitary. Ibintu bya pituitary bikora prolactin Imiti ikurikira ikoreshwa mu kugabanya umubare wa prolactin adenoma ya pituitary ikora. Nanone ishobora kugabanya igituntu. Cabergoline. Bromocriptine (Parlodel, Cycloset). Ingaruka mbi zishoboka zirimo: Kuzenguruka. Indwara zo mu mutwe, harimo kwiheba. Kubabara umutwe. Kugira intege nke. Bamwe mu bantu bagira imyitwarire y'ubwenge, nko kugira ibibazo byo kumarisha, mu gihe bafata iyi miti. Iyo myitwarire na yo yitwa impulse control disorders. Ibintu bya pituitary bikora adrenocorticotropic hormone Ibintu bikora adrenocorticotropic hormone, bita ACTH, biterwa n'umubiri gukora cortisol myinshi. Iyo ndwara izwi nka Cushing disease. Imiti ishobora kugabanya umubare wa cortisol umubiri ukora irimo: Ketoconazole. Metyrapone (Metopirone). Osilodrostat (Isturisa). Ingaruka mbi zishoboka z'iyi miti zirimo ikibazo cy'umutima gishobora gutera ikibazo gikomeye cy'umutima. Ikindi kintu cyitwa mifepristone (Korlym, Mifeprex) gishobora gukoreshwa ku bantu barwaye Cushing disease bafite diyabete yo mu bwoko bwa 2 cyangwa glucose intolerance. Mifepristone ntigabanya umubare wa cortisol umubiri ukora. Ahubwo, ibuza ingaruka za cortisol ku ngingo z'umubiri. Ingaruka mbi za mifepristone zirimo: Uburwayi. Kugira intege nke. Isesemi. Gukura amaraso menshi mu gitsina. Iyi miti yitwa pasireotide (Signifor) ikora igabanya umubare wa ACTH adenoma ya pituitary ikora. Ifatwa nk'urushinge kabiri ku munsi. Abaganga bakunze kugutekerezaho pasireotide iyo kubaga kugira ngo bakureho adenoma bitakora. Nanone bishobora gukoreshwa iyo adenoma idashobora gukurwaho hamwe no kubaga. Ingaruka mbi za pasireotide zirimo: Impiswi. Isesemi. Isukari y'amaraso iri hejuru. Kubabara umutwe. Kubabara mu nda. Uburwayi. Ibintu bya pituitary bikora imisemburo y'ubukure Ubwoko bubiri bw'imiti bushobora kuvura ibintu bya pituitary bikora imisemburo y'ubukure. Abaganga bakunze kwandika iyi miti iyo kubaga kugira ngo bakureho adenoma ya pituitary bitakorewe gusubiza umubare w'imisemburo y'ubukure mu mubiri ku rwego rwiza. Somatostatin analogs. Ubu bwoko bw'imiti bugabanya umubare w'imisemburo y'ubukure umubiri ukora. Nanone bishobora kugabanya igituntu cya pituitary. Somatostatin analogs irimo: Octreotide (Sandostatin). Lanreotide (Somatuline Depot). Iyi miti itangwa nk'urushinge, akenshi buri cyumweru 4. Uburyo bwa octreotide bushobora gufatwa mu kibindi, bwitwa Mycapssa, na bwo buraboneka. Ikora nk'uburyo butangwa nk'urushinge kandi ifite ingaruka mbi zimeze kimwe. Ingaruka mbi za somatostatin analogs zirimo: Isesemi no kuruka. Impiswi. Kubabara mu nda. Kuzenguruka. Kubabara umutwe. Kubabara aho urushinge rwatewe. Amabuye y'umwijima. Kwimuka kwa diyabete. Benshi muri izo ngaruka mbi ziratera imbere igihe kirekire. Pegvisomant (Somavert). Iyi miti ibuza ingaruka z'imisemburo myinshi y'ubukure ku mubiri. Ifatwa nk'urushinge buri munsi. Iyi miti ishobora gutera ingaruka mbi zo kwangiza umwijima kuri bamwe. Gusubiza imisemburo ya pituitary Gland ya pituitary igenzura ubukure, imikorere ya thyroid, imikorere ya adrenal, imikorere yo kubyara n'uburinganire bw'amazi mu mubiri. Kimwe cyangwa byose bishobora kwangizwa na adenoma ya pituitary cyangwa kuvurwa hamwe no kubaga cyangwa radiation. Ibi biterwa n'impinduka z'imisemburo zishobora gutera. Niba imisemburo yawe igwa ku rwego rutabereye, ushobora kuba ukeneye gufata imiti isubiza imisemburo. Ibi bishobora gusubiza imisemburo ku rwego rwiza. Gutegereza no kureba Mu gutegereza no kureba — bizwi kandi nko kureba, kuvura biteganijwe cyangwa kuvura byatinzwe — ushobora kuba ukeneye ibizamini byo gukurikirana kugira ngo urebe niba igituntu gikura cyangwa niba urwego rw'imisemburo ruhinduka. Gutegereza no kureba bishobora kuba amahitamo kuri wewe niba adenoma idatera ibimenyetso cyangwa itera ibindi bibazo by'ubuzima. Ganira n'umuvuzi wawe ku byiza n'ibyago byo gutegereza no kureba ugereranije no kuvurwa mu mimerere yawe. Amakuru y'inyongera Kwita ku bitunguru bya pituitary muri Mayo Clinic Ubuvuzi bwa stereotactic radiosurgery bw'ubwonko Craniotomy Proton therapy Radiation therapy Kugaragaza amakuru ajyanye menshi Gusaba gahunda Hari ikibazo gifitanye isano n'amakuru yatsinzwe hepfo kandi usubiremo ifishi. Bona inama zigezweho ku bitunguru by'ubwonko ukomoka muri Mayo Clinic bitangwa mu imeri yawe. Kwiyandikisha ubuntu kandi ubone amakuru agezweho ku kuvura ibintu by'ubwonko, ubuvuzi no kubaga. Imeri Adrese Iyi mimerere ya imeri irakenewe Kora imeri Adrese 1 Kwiyandikisha Menya byinshi ku ikoreshwa ry'amakuru rya Mayo Clinic. Kugira ngo tugutange amakuru afatika kandi akubereye, kandi dusobanukirwe amakuru afatika, dushobora guhuza imeri yawe n'amakuru y'imikorere ya website hamwe n'andi makuru dufite kuri wewe. Niba uri umurwayi wa Mayo Clinic, ibi bishobora kuba birimo amakuru y'ubuzima abarindwe. Niba duhuza aya makuru n'amakuru yawe y'ubuzima abarindwe, tuzabyita amakuru y'ubuzima abarindwe kandi tuzakoresha cyangwa tugaha ayo makuru nk'uko byagenwe mu itangazo ryacu ry'amabwiriza y'ibanga. Ushobora guhagarika imeri igihe icyo aricyo cyose ukande kuri link yo guhagarika mu imeri. Turagushimira kwandikisha Uzabona imeri ya mbere y'ibintu by'ubwonko mu imeri yawe vuba, izaba irimo amakuru ku kuvura, ubuvuzi, kubaga n'uko amakipe ya kanseri y'ubwonko muri Mayo Clinic abona ubufasha bwihariye. Mbabarira ikintu cyarangiye nabi n'iyandikisha ryawe Nyamuneka, gerageza ukundi mu minota mike Ongera

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