Icyo Abacavir na Lamivudine ari cyo: Ibyo bikoreshwa, urugero rwo gufata imiti, ingaruka ziterwa n'iyo miti n'ibindi

Abacavir na lamivudine ni umuti uvura SIDA uvura virusi mu mubiri wawe. Uyu muti wandikirwa na muganga urimo imiti ibiri ikomeye irwanya virusi, ikorera hamwe kugirango igabanye ubushobozi bwa SIDA bwo kwiyongera no gukwirakwira mu mubiri wawe.

Ushobora kumenya uyu muti ku mazina y'ubucuruzi nka Epzicom cyangwa Kivexa. Ni igice cy'uburyo bwo kuvura bushobora kugufasha kubaho ubuzima bwiza, burebure ufite SIDA iyo ufata imiti buri gihe nkuko byategetswe na muganga wawe.

Abacavir na Lamivudine ni iki?

Abacavir na lamivudine ni ikinini gihuza imiti, kirimo imiti ibiri itandukanye ya SIDA mu kinini kimwe. Ibikoresho byombi bigize itsinda ry'imiti yitwa nucleoside reverse transcriptase inhibitors, ikora ibyo ikingira SIDA kwigana muri selile zawe.

Ubu buryo bukorana butuma byoroha gufata imiti yawe ya SIDA kuko ubona imiti ibiri mu rugero rumwe. Uyu muti uza mu kinini kimira cyose, kandi ukoreshwa nk'igice cy'uburyo bwuzuye bwo kuvura SIDA hamwe n'indi miti irwanya virusi.

Muganga wawe azandika uyu muti nk'igice cy'icyitwa imiti ikora cyane irwanya virusi cyangwa HAART. Ubu buryo bukoresha imiti myinshi ya SIDA hamwe kugirango habeho uburyo bukomeye bwo kurwanya virusi mu mubiri wawe.

Abacavir na Lamivudine bikoreshwa kubera iki?

Uyu muti ukoreshwa by'umwihariko mu kuvura indwara ya HIV-1 mu bantu bakuru n'abana bapima nibura ibiro 25 (hafi ya 55 pounds). Ikora nk'igice cy'uburyo bwo kuvura buhuza kugirango igabanye umubare wa SIDA mu maraso yawe kugera ku rwego rutagaragara.

Intego nyamukuru ni ugufasha urwego rwawe rw'ubudahangarwa gukira no gukomera mugihe birinda SIDA gukura ikagera kuri SIDA. Iyo ikoreshejwe neza hamwe n'indi miti ya SIDA, ubu buryo bukorana bushobora kugufasha kugumana ubuzima busanzwe no kwirinda kwandura virusi ku bandi.

Umuvuzi wawe ashobora kugusaba uru ruhererekane rw'imiti niba utangiye kuvurwa na virusi itera SIDA ku nshuro ya mbere cyangwa niba ukeneye guhindura imiti uvura. Ni ngombwa gusobanukirwa ko uyu muti uvura virusi itera SIDA ariko ntuyikize burundu.

Abacavir na Lamivudine bikora bite?

Uyu muti uvura ukora mu kubuza virusi itera SIDA ubushobozi bwo kwikorera mu ngingo zawe. Abacavir na lamivudine byombi bibuza enzyme yitwa reverse transcriptase, virusi itera SIDA ikeneye kugira ngo yandukure ibikoresho byayo bya genetike kandi ikore udushya twa virusi.

Bitekereze nk'ugushyira urufunguzo mu byuma bya virusi itera SIDA. Iyo virusi igerageza kwiyongera, iyi miti irayibuza kurangiza neza icyo gikorwa. Ibi bifasha kugabanya umubare wa virusi mu maraso yawe uko igihe kigenda.

Uyu muti ufashwe nk'ufite imbaraga ziringaniye iyo uvuzwe hamwe n'indi miti ivura virusi itera SIDA. Nubwo ifite akamaro, ikora neza nk'igice cy'imiti itatu aho gukoreshwa yonyine, niyo mpamvu muganga wawe azakwandikira indi miti ivura virusi itera SIDA.

Nkwiriye gufata Abacavir na Lamivudine nte?

Ukwiriye gufata uyu muti nk'uko muganga wawe abitegeka, akenshi rimwe ku munsi hamwe cyangwa hatariho ibiryo. Iyi tablette irashobora gufatwa n'amazi, amata, cyangwa umutobe, kandi ntugomba guhangayika ku gihe cyo gufata ibiryo kuko ibiryo ntibigira ingaruka zikomeye ku buryo umubiri wawe wakira umuti.

Gerageza gufata urugero rwawe ku gihe kimwe buri munsi kugira ngo bifashe kugumana urwego rwawo ruriho neza mu mubiri wawe. Urashobora gushyiraho alarme ya buri munsi cyangwa ugakoresha umuteguro w'ibinini kugira ngo bikufashe kwibuka, kuko kutafata imiti bishobora gutuma virusi itera SIDA irwanya imiti.

Mimina tablette yose aho kuyikanda, kuyihekenya, cyangwa kuyimenagura. Niba ugira ikibazo cyo kumira ibinini, ganira na farumasiye yawe ku bijyanye n'uburyo bushobora kugufasha, ariko ntukahindure imiterere ya tablette utabiherewe uburenganzira.

Mbere yo gutangira uyu muti, muganga wawe azagupima ikimenyetso cya genetike cyitwa HLA-B*5701. Iyi igeragezwa ni ngombwa kuko abantu bafite iyi mpinduka ya genetike bafite ibyago byinshi byo kugira allergie zikomeye kuri abacavir.

Nzamara igihe kingana iki mfata Abacavir na Lamivudine?

Uzakeneye gufata uyu muti ubuzima bwawe bwose nk'igice cyo kuvura SIDA bikomeje. Kuvura SIDA ni gahunda y'igihe kirekire isaba imiti ya buri munsi kugira ngo virusi igumane hasi kandi urugingo rwawe rw'umubiri rukore neza.

Abantu benshi batangira kubona impinduka mu kigereranyo cyabo cya virusi mu byumweru 2-8 nyuma yo gutangira kuvurwa, n'igabanuka rikomeye risanzwe ribaho mu mezi 3-6. Muganga wawe azakurikiza iterambere ryawe binyuze mu igeragezwa ry'amaraso risanzwe kugira ngo arebe ko umuti ukora neza.

Ntuzigere uhagarika gufata uyu muti utabanje kuvugana n'umuganga wawe, kabone n'iyo wumva umeze neza rwose. Guhagarika kuvura SIDA birashobora gutuma virusi yororoka vuba kandi igashobora kwigiriza ubushobozi imiti, bigatuma kuvurwa mu gihe kizaza bigorana.

Ni izihe ngaruka ziterwa na Abacavir na Lamivudine?

Abantu benshi bakira neza uyu muti, ariko nk'imiti yose, irashobora gutera ingaruka. Ingaruka zisanzwe ni zoroshye kandi akenshi zinozwa uko umubiri wawe wimenyereza kuvurwa mu byumweru bya mbere.

Dore ingaruka zisanzwe ushobora guhura nazo:

• Umutwe no kunanirwa
• Isesemi no kuribwa mu nda
• Impiswi cyangwa imyanda yoroshye
• Kugorwa no gusinzira cyangwa inzozi zidasanzwe
• Umuzunguruko cyangwa kumva umutwe
• Izuru ryuzuye cyangwa rivamo amazi

Izi ngaruka za buri munsi zikunze kugabanuka uko umubiri wawe umenyera umuti. Niba zikomeje cyangwa zikabangamira imirimo yawe ya buri munsi, umuganga wawe ashobora gutanga ibitekerezo byo kuzicunga.

Ariko, hari ingaruka zikomeye zishobora kwitabwaho n'abaganga ako kanya, nubwo zitabaho cyane:

• Uburwayi bukomeye bwo kwanga ibintu (syndrome ya hypersensitivity)
• Lactic acidosis (kwiyongera kwa aside ya lactic mu maraso)
• Ibibazo bikomeye by'umwijima
• Uburwayi bwa hepatite B burushaho kuba bubi (niba ufite ubu burwayi)

Uburwayi bwo kwanga abacavir ni ingaruka ikomeye cyane. Bishobora gutera umuriro, ibiheri, umunaniro ukabije, kuribwa mu nda, n'ibimenyetso bisa n'ibya grip. Niba ubona ibi bimenyetso, cyane cyane mu byumweru bitandatu bya mbere uvurwa, vugana n'umuganga wawe ako kanya kandi ntuzongere gufata uyu muti.

Ninde utagomba gufata Abacavir na Lamivudine?

Ntugomba gufata uyu muti niba ufite allergie kuri abacavir, lamivudine, cyangwa izindi ngingo zose ziri muri iyi tablet. Byongeye kandi, niba uryamiye HLA-B*5701 genetic marker, umuganga wawe azahitamo uburyo bwo kuvura SIDA butandukanye kugirango wirinde ingaruka zikomeye ziterwa no kwanga ibintu.

Abantu bafite indwara y'umwijima yo hagati cyangwa ikomeye bashobora gukenera imiti itandukanye cyangwa imiti isimbura. Umuganga wawe azasuzuma imikorere y'umwijima wawe mbere yo gutangira kuvurwa kandi azajya abikurikirana buri gihe ukoresha uyu muti.

Niba ufite ibibazo by'impyiko, umuganga wawe ashobora gukenera guhindura urugero rwawe cyangwa agatekereza ku miti isimbura. Ibice byombi by'uyu muti bikoreshwa binyuze mu mpyiko zawe, bityo imikorere mibi y'impyiko ishobora kugira ingaruka ku buryo umuti ukora mu mubiri wawe.

Abagore batwite basanzwe bafata uyu muti, ariko gukurikiranwa neza ni ngombwa. Niba uteganya gutwita cyangwa ukamenya ko utwite ukoresha uyu muti, vugana n'umuganga wawe ako kanya ku byerekeye ibyago n'inyungu.

Amazina y'ubwoko bwa Abacavir na Lamivudine

Amazina y'ubwoko bw'imiti isanzwe ikoreshwa y'iyi mvange ni Epzicom muri Leta Zunze Ubumwe z'Amerika na Kivexa mu bindi bihugu. Zombi zikubiyemo ingano zimwe z'ibintu bikora: 600 mg ya abacavir na 300 mg ya lamivudine kuri buri kinini.

Ubundi bwoko bw'imiti bushobora kuboneka mu turere tumwe na tumwe, bukaba burimo ibintu bikora bimwe ariko bushobora kugira ibindi bintu bitagira akamaro cyangwa isura itandukanye. Umufarumasiti wawe ashobora kugufasha kumenya niba urimo guhabwa izina ry'ubwoko cyangwa ubwoko rusange.

Buri gihe banuza umuganga wawe mbere yo guhindura hagati y'amazina y'ubwoko n'ubwoko rusange, kuko bazashaka kumenya neza ko hariho guhuza mu buryo uvurwa.

Izindi Miti Ishobora Gusimbura Abacavir na Lamivudine

Izindi mvange z'imiti ivura SIDA zirashobora gukora nk'izindi niba iyi mvange idakwiriye kuri wewe. Muganga wawe ashobora gutekereza emtricitabine na tenofovir (Truvada), emtricitabine na tenofovir alafenamide (Descovy), cyangwa izindi mvange z'ibintu bikora mu buryo bwa nucleoside reverse transcriptase inhibitor.

Ku bantu badashobora gufata abacavir kubera HLA-B*5701 positivity, izindi zikunze kuba zirimo tenofovir-based combinations. Izi zikora kimwe zibungabunga kwiyongera kwa SIDA ariko zigakoresha uburyo butandukanye kandi zikagira ingaruka zitandukanye.

Umuvuzi wawe azatekereza ibintu nk'imikorere y'impyiko zawe, ubuzima bw'amagufa, izindi ndwara, n'imikoranire y'imiti ishobora kubaho mugihe atoranya igisubizo cyiza kuburyo bwihariye.

Ese Abacavir na Lamivudine biruta Tenofovir na Emtricitabine?

Zombi zombi ni imiti ivura SIDA ikora cyane, ariko nta n'imwe iruta iyindi. Guhitamo biterwa n'ubuzima bwawe bwite, ibintu bya genetike, n'uburyo wihanganira buri muti.

Abacavir na lamivudine bishobora gukundwa niba ufite ibibazo by'impyiko cyangwa ibibazo by'ubucucike bw'amagufa, kuko tenofovir rimwe na rimwe ishobora kugira ingaruka kuri ibyo bice. Ariko, imiti ivanze ya tenofovir ishobora guhitwamo niba wagaragayeho HLA-B*5701 cyangwa ufite indwara zimwe na zimwe z'umwijima.

Muganga wawe azatekereza ku mateka yawe yose y'ubuzima, ibisubizo bya laboratoire, n'ibyo ukunda ku giti cyawe mugihe afata icyemezo cy'uburyo bukwiriye kuri wowe. Zombi zifite amateka yizewe mu bushakashatsi bwa kliniki no gukoreshwa mu buzima busanzwe.

Ibibazo Bikunze Kubazwa Kuri Abacavir na Lamivudine

Ese Abacavir na Lamivudine birakwiriye ku bantu barwaye Hepatite B?

Uyu muti ushobora gukoreshwa ku bantu barwaye hepatite B, ariko bisaba gukurikiranwa neza. Lamivudine ifite imikorere irwanya virusi ya hepatite B, bityo niba ufite HIV na hepatite B, guhagarika uyu muti byatuma hepatite B yawe yiyongera cyane.

Muganga wawe azakurikirana imikorere y'umwijima wawe neza kandi ashobora kugusaba indi miti ya hepatite B niba bikwiye. Ntukigere uhagarika gufata uyu muti utabiherewe uburenganzira na muganga niba ufite hepatite B.

Nigute nzakora niba mfashe Abacavir na Lamivudine nyinshi ku buryo butunganye?

Niba ufata umuti mwinshi ku buryo butunganye, vugana n'umuganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. Nubwo ibimenyetso bikomeye byo kurenza urugero bidakunze kubaho kuri uyu muti, gufata mwinshi bishobora kongera ibyago byo kugira ingaruka ziterwa n'umuti.

Ntugerageze gusubiza umuti wanyuzeho usimbuka doze yawe ikurikira. Ahubwo, komeza gahunda yawe isanzwe yo gufata imiti keretse muganga wawe abiguhayeho inama zitandukanye.

Nigute nzakora niba nciweho doze ya Abacavir na Lamivudine?

Niba wibagiwe gufata doze, yifate ako kanya wibukiye, keretse igihe cyo gufata doze yawe ikurikira kigeze. Muriyo mbonerahamwe, simbuka doze wibagiwe hanyuma ufate doze yawe ikurikira ku gihe gisanzwe.

Ntugasuzume imiti ibiri icyarimwe kugira ngo usimbure urugero rwasibye. Niba ukunda kwibagirwa imiti, ganira n'umuganga wawe ku bijyanye n'uburyo bwo kugufasha kwibuka, nko gushyiraho alarme kuri telefoni cyangwa gukoresha ibikoresho byo gutegura imiti.

Nshobora Kureka Gufata Abacavir na Lamivudine ryari?

Ntugomba na rimwe kureka gufata uyu muti utabanje kubiganiraho n'umuganga wawe. Ubuvuzi bwa SIDA burambye, kandi kureka imiti birashobora gutuma virusi yororoka vuba kandi ikaba yakwihindura.

Muganga wawe ashobora guhindura imiti yawe niba ubonye ingaruka ziterwa n'imiti cyangwa niba imiti mishya ibonetse, ariko iki cyemezo kigomba gufatwa buri gihe hamwe n'ubuyobozi bwa muganga.

Nshobora Kunywa Alcool niba Ndafata Abacavir na Lamivudine?

Kunywa alcool mu rugero ruciriritse muri rusange birakwiriye mugihe ufata uyu muti, ariko kunywa cyane bishobora kongera ibyago byo kurwara umwijima kandi bishobora kubangamira imikorere y'imiti yawe ya SIDA.

Niba urwaye umwijima cyangwa ufite amateka y'ibibazo by'inzoga, ganira ku kunywa alcool n'umuganga wawe. Bashobora gutanga ubuyobozi bwihariye bushingiye ku buzima bwawe bwihariye.