Icyo Abacavir-Dolutegravir-Lamivudine ari cyo: Ibyo ikoreshwa, urugero rwo gufata, ingaruka ziterwa n'iyo miti n'ibindi

Abacavir-dolutegravir-lamivudine ni umuti uvura indwara ya virusi itera SIDA (VIH). Iyi tablet imwe irimo imiti itatu itandukanye ivura VIH ikorera hamwe kugira ngo ifashe kugenzura virusi mu mubiri wawe.

Niba warandikiwe uyu muti, urimo gufata icyo abaganga bita "uburyo bwuzuye" mu gipimo kimwe. Ibi bivuze ko udakeneye gufata imiti myinshi itandukanye ya VIH umunsi wose, ibyo bishobora koroshya imicungire y'imiti yawe.

Abacavir-Dolutegravir-Lamivudine ni iki?

Uyu muti uhuza imiti itatu ikomeye ya VIH muri tablet imwe yoroshye. Igice cyose gitera VIH mu buryo butandukanye kugira ngo birinde virusi kwiyongera mu mubiri wawe.

Abacavir na lamivudine ni mu itsinda ryitwa nucleoside reverse transcriptase inhibitors (NRTIs). Tekereza kuri ibi nk'ibikoresho bibuza VIH kwigana. Dolutegravir ni integrase strand transfer inhibitor (INSTI) ibuza virusi gushyira ibikoresho byayo bya genetike mu ntsinga zawe zifite ubuzima.

Hamwe, iyi miti itatu irema icyo abaganga bita "ubuvuzi buhuriweho butatu." Ubu buryo bwagaragaye ko bufite akamaro kanini mu kugabanya VIH kugeza ku rwego rutagaragara muri benshi bafata iyi miti buri gihe.

Abacavir-Dolutegravir-Lamivudine ikoreshwa mu kuvura iki?

Uyu muti uvura indwara ya VIH-1 mu bantu bakuru n'abana bapima nibura ibiro 25 (hafi ya 55 pounds). Yagenewe kugabanya umubare wa VIH mu maraso yawe kugeza ku rwego rutashobora kugaragazwa n'ibizamini bisanzwe.

Muganga wawe ashobora kukwandikira uyu muti nk'ubuvuzi bwawe bwa mbere bwa VIH niba urwaye vuba. Ikoreshwa kandi ku bantu bahindura imiti ya VIH, cyane cyane niba ubuvuzi bwabo butagikora neza nkuko byari byitezwe.

Intego ry'iyi miti ni ukugufasha kugera ku rwego rwa "virusi itagaragara" no kurugumana. Iyo urwego rwa virusi ya SIDA rutagaragara, ushobora kubaho ubuzima bwiza kandi ntuzanduza virusi abo mwashakanye.

Abacavir-Dolutegravir-Lamivudine ikora ite?

Iyi miti ifatwa nk'imiti ikomeye kandi ifite akamaro kanini ya SIDA. Ikora irwanya virusi ya SIDA mu byiciro bibiri bitandukanye by'ubuzima bwayo, bigatuma virusi itabasha kubaho no kwiyongera.

Ibice bya abacavir na lamivudine bikora nk'ibice by'ubwubatsi by'ubwambuzi iyo virusi ya SIDA igerageza kwigana. Iyo virusi ikoresha ibi bice by'ubwambuzi, ntishobora kurangiza uburyo bwo kwigana kandi irapfa. Hagati aho, dolutegravir ibuza intambwe itandukanye aho virusi ya SIDA igerageza gushyira kode yayo ya genetike mu ngirangingo zawe zifite ubuzima bwiza.

Ubu buryo bukoresha ibikorwa bibiri nibwo butuma iyi miti ikomera cyane. Niyo ibice bimwe na bimwe bya virusi byashobora kurenga inzitizi imwe, uburyo bwa kabiri burahari kugirango bubahagarike. Abantu benshi babona urwego rwabo rwa virusi rugabanuka cyane mu byumweru bike bya mbere by'imiti.

Nkwiriye gufata Abacavir-Dolutegravir-Lamivudine nte?

Fata iyi miti nkuko muganga wawe abitegeka, akenshi urupapuro rumwe rimwe ku munsi. Urashobora kuyifata hamwe n'ibiryo cyangwa utabifite, ariko gerageza kuyifata ku gihe kimwe buri munsi kugirango ugumane urwego ruzigama mu mubiri wawe.

Mimina urupapuro rwose n'amazi. Ntukoreshe, ntukore, cyangwa ugabanye urupapuro, kuko ibi bishobora kugira ingaruka ku buryo imiti yinjira. Niba ugira ikibazo cyo kumira ibinini, ganira na muganga wawe kubyerekeye ubundi buryo.

Gushyiraho umwibutso wa buri munsi kuri terefone yawe birashobora kugufasha kwibuka gufata imiti yawe. Guhora ukora ni ngombwa kugirango iyi miti ikore neza. Kudafata imiti bishobora korohereza virusi ya SIDA kwiyongera kandi bishobora guteza imbere kurwanya imiti.

Nkwiriye gufata Abacavir-Dolutegravir-Lamivudine igihe kingana iki?

Ukeneye gufata uyu muti ubuzima bwawe bwose kugira ngo ugumye HIV ku murongo. Bitandukanye na antibiyotike ufata mu gihe gito, imiti ya HIV ikora igihe cyose ukomeje kuyifata.

Ibi bishobora kumera nk'ibigoye mu ntangiriro, ariko wibuke ko abantu babarirwa muri za miliyoni babaho ubuzima bwuzuye kandi bwiza mu gihe bafata imiti ya HIV buri munsi. Ikintu cy'ingenzi ni ukubigira igice cy'ubuzima bwawe bwa buri munsi, kimwe no kumesa amenyo yawe.

Muganga wawe azakurikiza uko urimo utera imbere akoresheje ibizamini by'amaraso bya buri gihe kugira ngo arebe ko umuti ukora neza. Niba ubonye ingaruka ziterwa n'umuti cyangwa ibindi bibazo, ashobora guhindura uburyo uvurwa, ariko guhagarika imiti ya HIV ntibisanzwe kuba amahitamo.

Ni izihe ngaruka ziterwa na Abacavir-Dolutegravir-Lamivudine?

Abantu benshi bakira neza uyu muti, ariko nk'imiti yose, ishobora gutera ingaruka. Inkuru nziza ni uko ingaruka nyinshi zoroheje kandi zishobora kuzamo impinduka uko umubiri wawe wimenyereza umuti.

Dore ingaruka zisanzwe ushobora guhura nazo mu byumweru bike bya mbere:

• Umutwe no kunanirwa
• Isesemi cyangwa kutamererwa neza mu gifu
• Kugorwa no gusinzira cyangwa kurota inzozi zigaragara
• Impiswi cyangwa impinduka mu myitwarire y'amara
• Urugero, cyane cyane iyo uhagurutse vuba

Ibi bimenyetso mubisanzwe biragabanuka uko umubiri wawe umenyera umuti. Gufata ikinini hamwe n'ibiryo bishobora gufasha kugabanya ingaruka ziterwa n'igifu.

Hariho kandi ingaruka zimwe na zimwe zidakunze kubaho ariko zikomeye zisaba ubufasha bwihutirwa bwa muganga. Nubwo ibi bitabaho kenshi, ni ngombwa kumenya icyo ugomba kwitaho:

• Uburwayi bukomeye bwo kwibasirwa n'ibintu bitera allergie kuri abacavir (umuriro, amabara ku ruhu, isesemi, kuruka, kunanirwa cyane)
• Lactic acidosis (kubabara imitsi bidasanzwe, kugorwa no guhumeka, kuribwa mu nda, kumva umuntu ananiwe cyane)
• Uburwayi bukomeye bw'umwijima (uruhu cyangwa amaso y'umuhondo, inkari z'umukara, kuribwa cyane mu nda)
• Agahinda gakabije cyangwa ibitekerezo byo kwigirira nabi
• Kongera ibiro bidasanzwe, cyane cyane hafi y'umubiri wo hagati no mu mugongo w'ijosi

Niba ubonye kimwe muri ibi bimenyetso bikomeye, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bwihutirwa. Umutekano wawe ni wo uza imbere, kandi akenshi hari uburyo bwo guhindura imiti yawe niba bibaye ngombwa.

Ninde utagomba gufata Abacavir-Dolutegravir-Lamivudine?

Uyu muti ntukwiriye buri wese. Umuganga wawe azasuzuma amateka yawe y'ubuzima kandi ashobora gutegeka ibizamini byihariye mbere yo kuwandikira.

Ntugomba gufata uyu muti niba ufite allergie ku bice byawo byose, cyane cyane abacavir. Mbere yo gutangira kuvurwa, umuganga wawe ashobora kugupima ikimenyetso cya genetique cyitwa HLA-B*5701 kiyongera ibyago byo kwibasirwa bikomeye na abacavir.

Abantu bafite indwara zimwe na zimwe bagomba kwitonda cyane cyangwa bashobora gukenera imiti itandukanye:

• Indwara ikomeye y'umwijima, harimo hepatite B cyangwa C
• Ibibazo by'impyiko cyangwa indwara y'impyiko
• Amateka y'indwara y'umutima cyangwa ibyago byinshi bya cardiovascular
• Indwara zo mu mutwe, cyane cyane agahinda gakabije
• Ibibazo by'amagufa cyangwa ibyago bya osteoporosis

Niba utwite cyangwa uteganya gutwita, biganireho n'umuganga wawe. Nubwo kuvura SIDA mugihe cyo gutwita ari ngombwa, umuganga wawe ashobora kugusaba uruvange rw'imiti itandukanye yizezwe cyane mu bagore batwite.

Amazina y'ubwoko bwa Abacavir-Dolutegravir-Lamivudine

Uru ruvange rw'imiti rugurishwa ku izina rya Triumeq mu bihugu byinshi. Ushobora kandi kurubona rwitwa izina ryarwo rusanzwe cyangwa nka "ABC/DTG/3TC" mu buvuzi.

Ibice bigize umuti na byo biboneka nk'imiti yihariye cyangwa mu zindi mvange. Ariko, gufata urubuto rumwe rugizwe n'imiti itatu mubisanzwe biroroshye kandi bifasha kumenya neza ko ubona imiti yose uko ari itatu mu rugero rukwiye.

Buri gihe menya neza ko ubona umuti neza nk'uko muganga wawe yabigutegetse. Niba farumasi isimbuye izina ry'umuti cyangwa uwo mu bwoko bwa generic, ganira na muganga wawe kugira ngo umenye neza niba bikwiye ku miterere yawe.

Izindi mvange zishobora gusimbura Abacavir-Dolutegravir-Lamivudine

Hariho izindi mvange z'imiti ivura virusi itera SIDA ziboneka niba iyi itagukwiriye. Muganga wawe ashobora gutekereza izindi mvange bitewe n'ibyo ukeneye byihariye, ingaruka ziterwa n'umuti, cyangwa izindi ndwara.

Izindi mvange z'imiti ivura SIDA zifata rimwe ku munsi zirimo imvange zifite ibindi bice byitwa integrase inhibitors nka bictegravir cyangwa imvange zishingiye kuri rilpivirine. Hariho kandi uburyo butarimo abacavir niba ufite allergie kuri icyo gice.

Guhitamo umuti uvura SIDA biterwa n'ibintu byinshi, harimo umubare wa virusi mu maraso yawe, umubare wa CD4, izindi ndwara, n'uburyo imiti ishobora gukurikiranwa. Muganga wawe azakorana nawe kugira ngo abone uburyo bukwiye bujyanye n'imibereho yawe n'ibyo ukeneye mu buzima.

Ese Abacavir-Dolutegravir-Lamivudine iruta indi miti ivura SIDA?

Uyu muti ufatwa nk'umwe mu miti ivura SIDA ikora neza cyane ubu. Ubushakashatsi bwa muganga bwerekana ko bigenda neza cyane mu kugabanya virusi itera SIDA kugeza ku rwego rutagaragara ku bantu benshi bawufata buri gihe.

Ugereranije n'imiti ivura SIDA ya kera, iyi mvange itanga inyungu nyinshi. Bisaba urubuto rumwe gusa rimwe ku munsi, ifite ingaruka nkeya zo gukurikiranwa, kandi ikunda gutera ingaruka nke. Igice cya dolutegravir gikora neza cyane kandi gifite urukuta rwo kurwanya rwo hejuru.

Ariko, "neza" biterwa n'uko ubuzima bwawe bumeze. Abantu bamwe bashobora kwitabira neza imiti itandukanye, cyangwa bakagira indwara zituma izindi nzira zikwiriye kurushaho. Muganga wawe azatekereza ku byo urimo kugenda kugira ngo aguhitemo uburyo bwiza bwo kukuvura.

Ibikunze Kubazwa Kuri Abacavir-Dolutegravir-Lamivudine

Ese Abacavir-Dolutegravir-Lamivudine irakwiriye ku bantu barwaye Hepatite B?

Uyu muti usaba kwitonda cyane niba urwaye hepatite B. Ibice bibiri byawo (abacavir na lamivudine) bikoreshwa kandi mu kuvura hepatite B, bityo kubihagarika mu buryo butunguranye bishobora gutuma hepatite B yawe yongera ubukana.

Niba ufite virusi ya SIDA na hepatite B, muganga wawe azakugenzura cyane kandi ashobora gukenera kongeraho undi muti wa hepatite B niba ukeneye guhagarika uyu muti. Ntukigere uhagarika gufata uyu muti utabanje kuvugana na muganga wawe, cyane cyane niba ufite hepatite B.

Nkwiriye gukora iki niba nanyweye Abacavir-Dolutegravir-Lamivudine nyinshi mu buryo butunguranye?

Niba unyweye umuti mwinshi kuruta uko wategetswe, vugana na muganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. N'ubwo urugero rumwe rurenze urwo wategetswe rutashobora guteza ingaruka zikomeye, ni ngombwa kubanza kubaza inama ya muganga.

Ntugerageze "gusubiza" urugero rurenze urwo wanyweye ukora ku buryo utafata urugero rukurikira. Ahubwo, komeza gahunda yawe yo kunywa imiti nk'uko byategetswe na muganga wawe. Bika umuti mu gikoresho cyawo cy'umwimerere kandi uwubike ahantu hizewe hatagerwaho n'abana n'amatungo.

Nkwiriye gukora iki niba nciweho urugero rwa Abacavir-Dolutegravir-Lamivudine?

Niba waciweho urugero kandi hashize amasaha atarenze 12 uhereye igihe cyari gisanzwe, unywe urugero wibagiwe ako kanya. Niba hashize amasaha arenga 12, reka urugero wibagiwe hanyuma unywe urugero rukurikira ku gihe cyagenwe.

Ntugomba gufata doze ebyiri icyarimwe kugira ngo usimbure doze wasibye. Ibi bishobora kongera ibyago byo kugira ingaruka mbi utagize inyungu yinyongera. Niba ukunda kwibagirwa gufata imiti, ganira na muganga wawe ku bijyanye n'uburyo bwo kugufasha kwibuka, nk'ibikoresho bifasha kwibuka imiti cyangwa porogaramu za telefone.

Ni ryari nshobora kureka gufata Abacavir-Dolutegravir-Lamivudine?

Ntugomba na rimwe kureka gufata uyu muti utabanje kuvugana na muganga wawe. Imiti ivura SIDA ikora gusa igihe ukomeje kuyifata, kandi kuyihagarika bishobora gutuma virusi yororoka vuba kandi ikaba yatera ubudahangarwa.

N'ubwo wumva umeze neza rwose kandi umubare wa virusi yawe utagaragara, uyu muti niwo ukomeza kugenzura virusi. Niba urimo guhura n'ingaruka mbi cyangwa izindi mpungenge, ganira na muganga wawe kuri ibyo. Bashobora guhindura uburyo uvurwa cyangwa gufasha kugenzura ingaruka mbi utahagaritse umuti.

Nshobora gufata Abacavir-Dolutegravir-Lamivudine hamwe n'indi miti?

Uyu muti ushobora gukorana n'indi miti, bityo ni ngombwa kubwira muganga wawe imiti yose, ibiyobyabwenge, n'ibicuruzwa by'ibyatsi ufata. Imikorere imwe ishobora gutuma umuti wa SIDA utagira akamaro cyangwa ukongera ingaruka mbi.

Imiti isanzwe ishobora gukorana harimo imiti imwe na rimwe irwanya aside, imiti ivura indwara zo mu mutwe, na antibiyotike zimwe na zimwe. Muganga wawe cyangwa umufarumasiti ashobora kureba niba hari imikorere kandi akakugira inama ku gihe cyiza cyo gufata iyo ukeneye gufata indi miti. Buri gihe jya inama umuganga wawe mbere yo gutangira imiti mishya iyo ufata uyu muti uvura SIDA.