Icyo Abciximab ari cyo: Ibyo ikoreshwa, urugero rwo kuyifata, ingaruka zayo n'ibindi

Abciximab ni umuti ukomeye ufasha kwirinda amaraso mu gihe cyo kubaga umutima bikomeye. Ni umuti wihariye abaganga bakoresha mu bitaro iyo uri mu buvuzi bw'umutima nk'angioplasty cyangwa gushyiraho stent.

Uyu muti ukora ubu akingira uturemangingo duto tw'amaraso twitwa platelets kugira ngo tutifatanya. Tekereza nk'ikingira ry'agateganyo rikomeza amaraso yawe atembera neza mu gihe cy'ingenzi aho gukora amaraso bishobora kuba byateza akaga.

Abciximab ni iki?

Abciximab ni umuti wandikirwa na muganga wo mu itsinda ryitwa platelet inhibitors. Ni icyo abaganga bita

Rimwe na rimwe abaganga barayandikira abarwayi bafite ibikorwa byihutirwa by'umutima, cyane cyane niba ufite ibyago byinshi byo guteza imvura. Muganga wawe w'umutima ashobora no kubikugira inama niba ufite angina itajegajega - kubabara mu gituza bibaho mu buryo butunguranye.

Abciximab ikora ite?

Abciximab ikora ibuza imiterere yihariye kuri platelets zawe yitwa GP IIb/IIIa receptors. Izi receptors zimeze nk'ibibuga byo kwakiriraho aho platelets zisanzwe zihuza kugirango zikore imvura.

Iyo abciximab yifatanyije n'izi receptors, ibuza platelets guhuzwa. Ibi ni ngombwa cyane mugihe cy'ibikorwa by'umutima kuko ibikoresho n'ibikoresho bikoreshwa rimwe na rimwe bishobora gutera imvura itifuzwa.

Uyu muti ufatwa nk'ukomeye cyane - ukomeye cyane kuruta imiti isanzwe ikoreshwa mu gutuma amaraso atavura nka aspirine. Itanga uburinzi bukomeye ariko bw'igihe gito ku kuvura, ibyo ni byo bikenerwa mugihe cy'ibikorwa bifite ibyago byinshi.

Ingaruka zitangira mumunota muke wo gutangira gutera IV. Ubushobozi bw'amaraso yawe bwo kuvura buguma bugabanuka cyane mumasaha menshi, ndetse nyuma yo guhagarika umuti.

Nkwiriye gufata Abciximab nte?

Ntiwifatira abciximab wenyine - buri gihe itangwa nabaganga bafite ubumenyi mu bitaro. Uyu muti uza unyuze kumurongo wa IV, mubisanzwe mu kuboko kwawe cyangwa ukuboko.

Itsinda ryawe ry'ubuvuzi rizatangira n'urugero rwo gutwara, urwo ni urugero runini rwa mbere rutangwa vuba. Ibi bikurikirwa no gutera bikomeza bitanga urugero ruto mumasaha menshi.

Ntabwo ukeneye guhangayika kubijyanye n'ibiribwa mbere yo kwakira abciximab. Ariko, muganga wawe ashobora kukubwira kwirinda imiti cyangwa ibyongerera imbaraga bishobora kongera ibyago byo kuva amaraso.

Abakozi b'abaforomo bazagukurikiranira hafi muri ubu buryo bwose. Bazagenzura ibimenyetso byawe by'ingenzi buri gihe kandi barebe ibimenyetso byose byo kuva amaraso cyangwa izindi ngorane.

Nkwiriye gufata Abciximab igihe kingana iki?

Ubuvuzi bwa Abciximab burahora igihe gito, akenshi bumara amasaha 12 kugeza kuri 24. Igihe nyacyo giterwa n'uburyo wakoreweho n'ibintu bigushyira mu kaga.

Abantu benshi bahabwa uyu muti nyuma y'amasaha 12 bakoreweho ibijyanye n'umutima. Mu bindi bihe, cyane cyane iyo bakorewe ibikorwa bigoye, muganga wawe ashobora kongera ubuvuzi kugeza ku masaha 24.

Itsinda ryawe ry'abaganga rizagena igihe nyacyo hashingiwe ku buryo wakoreweho n'uburyo umubiri wawe witwaye. Bazareba ibintu nk'uko amaraso ava n'uburyo umutima wawe ukira.

Iyo gutera uyu muti bihagarara, ingaruka zawo zigenda zishira buhoro buhoro mu munsi umwe cyangwa ibiri ikurikira. Ubushobozi busanzwe bw'amaraso bwo gukora ibibumbe buragaruka, ariko ibi bibaho buhoro kugira ngo umutekano wawe wizerwe.

Ni izihe ngaruka ziterwa na Abciximab?

Ingaruka ikomeye cyane ya abciximab ni ukuva amaraso, bishobora kuva ku bito bikagera ku bikomeye. Ibi bibaho kuko uyu muti ugabanya ubushobozi bw'amaraso bwo gukora ibibumbe.

Dore ingaruka zisanzwe ushobora guhura nazo:

• Kuva amaraso ahantu batera umuti cyangwa ahantu bashyize catheter
• Gukomereka byoroshye ku ruhu rwawe
• Urugimbu cyangwa kutumva neza mu gifu
• Umutwe cyangwa isereri
• Kubabara umugongo, cyane cyane ahantu bakoreye
• Umubyimba muke w'amaraso

Izi ngaruka zikunda kugenzurwa kandi zikagenzurwa neza n'ikipe yawe y'ubuvuzi. Ahanini zikira zonyine igihe umuti uva mu mubiri wawe.

Ingaruka zikomeye ariko zitabaho kenshi zisaba ubufasha bwihuse bw'abaganga:

• Kuva amaraso menshi atahagarara no gushyiraho igitutu
• Amaraso mu nkari cyangwa mu musarani
• Kuva amaraso bidasanzwe mu ishinya cyangwa mu mazuru
• Kubabara cyane mu gituza cyangwa guhumeka nabi
• Ibimenyetso bya stroke nk'urujijo rwo mu mutwe cyangwa intege nke
• Urugero rukabije rw'uburwayi bwo mu mubiri hamwe n'ibibazo byo guhumeka

Itsinda ryawe ry’abaganga ryatojwe kumenya no kuvura ibi bibazo vuba. Bafite imiti n'inzira ziteguye kugirango bakureho ingaruka za abciximab niba bibaye ngombwa.

Ibikomere bidasanzwe ariko bikomeye birimo kuva amaraso menshi cyangwa thrombocytopenia - igabanuka ry'ubwoko bw'amaraso. Ibi bibaho ku barwayi batarenze 1% ariko bisaba ubufasha bwihuse.

Ninde utagomba gufata Abciximab?

Abciximab ntibishoboka kuri buri wese, cyane cyane abafite indwara ziyongera kuva amaraso. Muganga wawe azasuzuma neza amateka yawe mbere yo gufata icyemezo niba bikwiriye kuri wewe.

Ntabwo ugomba guhabwa abciximab niba ufite kuva amaraso ahantu hose mu mubiri wawe. Ibi birimo kuva amaraso bigaragara nko kuva amazuru cyangwa kuva amaraso yihishe nka ibisebe byo mu gifu.

Abantu bafite indwara zimwe na zimwe bagomba kwirinda iyi miti rwose:

• Kubagwa bikomeye vuba muri icyo gihe cy'ibyumweru 6 bishize
• Amateka y'indwara yo mu bwonko mu myaka 2 ishize
• Umubyigano ukabije w'amaraso utagendera
• Indwara zizwi zo kuva amaraso nka hemophilia
• Indwara zikomeye z'umwijima cyangwa impyiko
• Kanseri ikora ifite ibyago byo kuva amaraso
• Urugero rwa vuba cyangwa imvune yo mu mutwe

Muganga wawe azitonda kandi niba ufata indi miti ituma amaraso ataguma. Ubu buryo bushobora kongera cyane ibyago byo kuva amaraso hejuru y'urwego rw'umutekano.

Abagore batwite muri rusange ntibagomba guhabwa abciximab keretse inyungu zigaragara neza zirenze ibyago. Uyu muti ushobora kwambuka placenta kandi ugashobora kugira ingaruka ku mwana ukura.

Imyaka yonyine ntabwo ari ikintu cyo kutemererwa, ariko abantu bakuze bashobora gukenera guhindura urugero cyangwa gukurikiranwa cyane kubera kwiyongera kw'ubworoherane bwo kuva amaraso.

Amazina y'ubwoko bwa Abciximab

Abciximab akunda kumenyekana ku izina ry'ubwoko ReoPro. Iyi ni verisiyo y'umwimerere kandi ikoreshwa cyane y'uyu muti mu bitaro.

Bitandukanye n'imiti myinshi, abciximab ntigira amazina menshi y'ubwoko cyangwa ubwoko bwa rusange. ReoPro iracyakoreshwa nk'isanzwe mu bigo by'ubuvuzi ku isi yose.

Igihe muganira ku kuvurwa kwanyu n'abaganga, bashobora kubyita izina iryo ariryo ryose - abciximab cyangwa ReoPro. Ayo mazina yombi yerekeza ku muti umwe ufite ingaruka zimwe n'imibare imwe yo gufata.

Izindi Miti Ishobora Gusimbura Abciximab

Imiti myinshi ishobora gutanga uburyo bwo gukumira amaraso mu gihe cyo kubaga umutima. Muganga wawe ashobora guhitamo izindi miti bitewe n'uko ubuzima bwawe buteye n'ibintu bigushyira mu kaga.

Eptifibatide na tirofiban ni izindi miti ibiri ikora kimwe na abciximab. Nayo ni ibiyobyabwenge bya GP IIb/IIIa ariko bifite igihe gito cyo gukora.

Abaganga bamwe bakunda izi zindi miti kuko ingaruka zazo zishira vuba niba hari ibibazo by'amaraso bibaye. Ariko, ntibishobora gukora neza nka abciximab mu bikorwa byo mu kaga gakomeye.

Izindi miti ituma amaraso atavura nka heparin cyangwa bivalirudin ikora mu buryo butandukanye. Umuganga w'umutima wawe azahitamo uburyo bwiza bitewe n'ubwoko bw'ibikorwa byawe n'ubuzima bwawe bwite.

Ese Abciximab iruta Clopidogrel?

Abciximab na clopidogrel bikora mu buryo butandukanye kandi bifite intego zitandukanye mu kwita ku mutima. Ntabwo ari abakoresha bahanganye - ahubwo, akenshi bakoreshwa hamwe kugira ngo bagire umutekano mwinshi.

Abciximab itanga uburyo bwo gukumira amaraso ako kanya, mu gihe clopidogrel itanga uburyo bwo kurinda igihe kirekire ufata mu rugo. Tekereza abciximab nk'uburyo bwo kurinda bwihutirwa na clopidogrel nk'isuku ya buri munsi.

Mu bihe byihutirwa mu gihe cyo kubaga umutima, abciximab muri rusange irakora neza kuko ikora ako kanya kandi neza. Clopidogrel ifata iminsi kugira ngo igere ku ngaruka zose.

Ariko, clopidogrel ni nziza gukoresha igihe kirekire kandi ntisaba gukurikiranwa mu bitaro. Muganga wawe akenshi azakoresha byombi - abciximab mugihe cyo kubagwa kwawe na clopidogrel muminsi cyangwa amezi nyuma.

Ibibazo Bikunze Kubazwa Kuri Abciximab

Ese Abciximab ni nziza ku bantu barwaye diyabete?

Abciximab irashobora kuba nziza ku bantu barwaye diyabete, ariko hakenerwa ingamba zidasanzwe. Diyabete irashobora kugira ingaruka ku buzima bw'imitsi y'amaraso no gukira, ibyo ikipe yawe y'abaganga izabitekerezaho neza.

Abantu barwaye diyabete bashobora kugira ibyago byinshi byo kuva amaraso. Abaganga bawe bazagukurikiranira hafi kandi bashobora guhindura urugero cyangwa igihe cyo kuvurwa.

Niba ufite indwara ya retinopathy ya diyabete - ibibazo by'amaso biturutse kuri diyabete - muganga wawe azitonda cyane. Iyi ndwara irashobora kongera ibyago byo kuva amaraso mumaso.

Nigute nzakora niba mbonye Abciximab nyinshi bitunguranye?

Ntushobora kubona Abciximab nyinshi bitunguranye kuko abaganga babihuguriwe bagenzura urugero. Ariko, niba habayeho kwiyongera, ubufasha bwihuse bw'ubuvuzi burahari.

Ibitaro bifite uburyo bwihariye bwo guhindura ingaruka za abciximab. Ibi birashobora gukubiyemo gutanga platelet cyangwa izindi miti isubiza iseswa risanzwe ry'amaraso.

Ikipe y'abaganga ikurikirana urugero rwo guseseka kw'amaraso yawe mugihe cyo kuvurwa. Barashobora kumenya vuba niba umuti ufite ingaruka zikomeye kandi bakabihindura uko bikwiye.

Nigute nzakora niba ntasibye urugero rwa Abciximab?

Kutabona urugero rwa abciximab ntabwo ari ikintu ugomba guhangayikishwa. Uyu muti utangwa buri gihe binyuze muri IV, bityo ikipe y'abaganga igenzura igihe.

Niba hariho ikibazo mu gutera IV yawe, abaforomo bawe bazongera kuyitangira vuba. Bazagenzura niba ukeneye undi muti wo gukomeza kurinda.

Itsinda ryawe ry’abaganga rifite amabwiriza yo guhangana n’inzitizi zose zigaragara mu kuvura. Bazakora ibishoboka byose kugira ngo uhabwe umuti ukwiye ukurikije uko ubuzima bwawe buhagaze.

Nshobora Kureka Gufata Abciximab Ryari?

Ntabwo ari wowe ufata icyemezo cyo kureka gufata abciximab - itsinda ryawe ry’abaganga niyo rifata icyo cyemezo hashingiwe ku buryo wakoreweho n’uburyo urimo gukira. Uyu muti akenshi uhagarara wenyine nyuma y’igihe cyagenwe.

Abantu benshi barwara bahabwa abciximab mu masaha 12 kugeza kuri 24 nyuma yo kubagwa umutima. Muganga wawe azagena igihe nyacyo hashingiwe ku buryo urimo gukira n’uko amaraso yawe akora.

Mbere yo guhagarika uyu muti, itsinda ryawe ry’abaganga rizagenzura neza niba aho bakubaze hameze neza kandi niba nta kaga ko gukora ibibazo by’amaraso. Bazakomeza kugukurikirana kabone niyo imiti yarangiye.

Nshobora Gutwara Imodoka Nyuma yo Gufata Abciximab?

Ntabwo wagombye gutwara imodoka nibura mu masaha 24 nyuma yo gufata abciximab, kandi bishobora no gutinda bitewe n’uburyo wakoreweho. Uyu muti ushobora gutera isereri kandi ukongera ibyago byo kuva amaraso niba wagize ikibazo.

Abantu benshi bafata abciximab barimo gukira ibibazo by’umutima bisaba iminsi myinshi yo kuruhuka. Muganga wawe azakubwira igihe bizaba byemewe gusubira mu bikorwa bisanzwe nk’uko gutwara imodoka.

Niyo imiti yarangira, ushobora gukenera kwirinda gutwara imodoka kugeza igihe aho bakubaze hazakira neza. Ibi birinda ibibazo niba ukeneye guhagarara vuba cyangwa kwihuta.