Aliskiren ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Aliskiren ni umuti wandikirwa na muganga ufasha kugabanya umuvuduko w'amaraso uri hejuru binyuze mu guhagarika imyunyungugu yihariye mu mubiri wawe. Uyu muti ubarirwa mu cyiciro cyihariye cy'imiti igabanya umuvuduko w'amaraso yitwa inhibitors ya renin itaziguye, ikora mu buryo butandukanye n'indi miti isanzwe igabanya umuvuduko w'amaraso ushobora kuba warumviseho.

Uyu muti ushobora kuba igikoresho cyiza mu kugenzura umuvuduko w'amaraso uri hejuru iyo izindi nshingano zitagize icyo zigeraho. Muganga wawe ashobora kukwandikira aliskiren nk'igice cy'uburyo bwuzuye bwo kurengera umutima wawe n'imitsi y'amaraso ku ngaruka zirambye ziterwa n'umuvuduko w'amaraso uri hejuru.

Aliskiren ni iki?

Aliskiren ni umuti wandikirwa na muganga ugabanya umuvuduko w'amaraso ukora mu guhagarika renin, imyunyungugu impyiko zawe zikora. Tekereza renin nk'idomino rya mbere mu murongo w'ibikorwa bituma umuvuduko w'amaraso wawe uzamuka.

Bitandukanye n'indi miti igabanya umuvuduko w'amaraso ikora nyuma muri uyu murongo w'ibikorwa, aliskiren ihagarika ubu buryo ku ikubitiro. Ibi bituma bikoreshwa cyane cyane ku bantu bakeneye uburyo butandukanye bwo kugenzura umuvuduko w'amaraso.

Uyu muti uza mu buryo bw'ibinini kandi akenshi ufashwa rimwe ku munsi. Yagenewe gukoreshwa igihe kirekire nk'igice cyo kugenzura umuvuduko w'amaraso buri gihe, ntabwo ari nk'igisubizo cyihuse ku bipimo byo hejuru rimwe na rimwe.

Aliskiren ikoreshwa mu iki?

Aliskiren ikoreshwa cyane cyane mu kuvura umuvuduko w'amaraso uri hejuru (hypertension) mu bantu bakuru. Muganga wawe ashobora kukwandikira iyo umuvuduko w'amaraso yawe uhora uri 140/90 mmHg cyangwa hejuru, cyangwa iyo indi miti itagabanyije imibare yawe bihagije.

Uyu muti akenshi wandikwa iyo ukeneye kugenzura umuvuduko w'amaraso wiyongera urenze ibyo urimo kubona mu yindi miti. Ushobora gukoreshwa wenyine cyangwa uhujwe n'indi miti igabanya umuvuduko w'amaraso nka diuretics cyangwa calcium channel blockers.

Rimwe na rimwe, abaganga bandikira aliskiren abantu bafite ingaruka zatewe n'imiti ivura umuvuduko w'amaraso. Kubera ko ikora ikoresheje uburyo butandukanye, irashobora kwihanganirwa neza n'abarwayi bamwe.

Aliskiren ikora ite?

Aliskiren ikora ibuza renin, uruganda rwo mu mubiri wawe rwo mu mpyisi rusohora iyo rusanze umuvuduko w'amaraso uri hasi cyangwa amaraso atembera make. Ibi bifatwa nk'umuti uvura umuvuduko w'amaraso ukomeye, ugamije ikibazo cy'ingenzi cy'inzira imwe y'umuvuduko w'amaraso.

Iyo renin yabuze, ntishobora gutangiza urukurikirane ruzana angiotensin II, ikintu gikomeye gifunga imitsi y'amaraso kandi kikazamura umuvuduko w'amaraso. Mu guhagarika iyi nzira hakiri kare, aliskiren ifasha kugumisha imitsi yawe y'amaraso yoroshye.

Uyu muti akenshi utangira gukora mu masaha make nyuma yo kuwufata, ariko ntushobora kumva ingaruka zose mu byumweru byinshi. Iyi ngaruka igenda buhoro ni nziza kuko yemerera umubiri wawe guhinduka neza ku rwego rwo hasi rw'umuvuduko w'amaraso.

Nkwiriye gufata aliskiren nte?

Fata aliskiren nk'uko umuganga wawe abikwandikira, akenshi rimwe ku munsi ku gihe kimwe buri munsi. Urashobora kuyifata hamwe n'ibiryo cyangwa utabifite, ariko gerageza kubigiraho ubwitonzi kugirango ugumane urwego ruzigama mu mubiri wawe.

Mimina urupapuro rwose hamwe n'ikirahure cyuzuye cy'amazi. Ntugasenya, ntugahahane, cyangwa ngo umene urupapuro, kuko ibi bishobora kugira ingaruka ku buryo umuti usohoka mu mubiri wawe.

Niba ufata aliskiren hamwe n'ibiryo, irinda amafunguro arimo amavuta menshi kuko ashobora kugabanya uburyo umubiri wawe wunguka umuti. Amafunguro yoroheje cyangwa kuyifata ku gifu cyuzuye bikora neza kugirango wongere ubwinjiriro.

Gerageza gufata urugero rwawe ku gihe kimwe buri munsi kugirango bigufashe kwibuka no kugumisha urwego ruzigama rw'umuti mu mubiri wawe. Abantu benshi basanga bifasha kuyifata hamwe n'ibikorwa byabo bya mugitondo.

Nkwiriye gufata aliskiren igihe kingana iki?

Aliskiren akenshi yandikirwa gukoreshwa igihe kirekire, akenshi mu mezi cyangwa imyaka, kuko umuvuduko ukabije w'amaraso akenshi ni indwara idakira isaba gukomeza kuvurwa. Muganga wawe azagena igihe cyiza gishingiye ku buryo wabyakiriyeho n'ubuzima bwawe muri rusange.

Ntukareke gufata aliskiren ako kanya, kabone n'iyo wumva umeze neza cyangwa ibipimo by'umuvuduko w'amaraso yawe bigenda neza. Umuvuduko ukabije w'amaraso akenshi ntugira ibimenyetso, bityo kumva umeze neza ntibisobanura ko ushobora guhagarika umuti.

Muganga wawe azajya akurikirana umuvuduko w'amaraso yawe n'imikorere y'impyiko zawe igihe uri gufata aliskiren. Dushingiye kuri ibi bisuzumwa, bashobora guhindura urugero rw'umuti wawe cyangwa bakazakugeza ku buryo butandukanye bwo kuvurwa.

Abantu bamwe bashobora gukenera gufata imiti igabanya umuvuduko w'amaraso ubuzima bwabo bwose, mu gihe abandi bashobora kugabanya cyangwa kuyihagarika niba impinduka mu mibereho yabo zigaragaza impinduka nziza mu buzima bw'umutima n'imitsi y'amaraso.

Ni Ibihe Bimenyetso Bigaragara Byatewe na Aliskiren?

Kimwe n'indi miti yose, aliskiren ishobora gutera ibimenyetso bigaragara, nubwo abantu benshi bayihanganira neza. Ibimenyetso bigaragara byinshi ni bike kandi bikunda gukira uko umubiri wawe wimenyereza umuti.

Dore ibimenyetso bigaragara bikunze kugaragara ushobora guhura nabyo:

• Impiswi cyangwa imyanda yoroshye
• Urugero, cyane cyane iyo uhagurutse vuba
• Umunaniro cyangwa kumva unaniwe
• Umutwe
• Isesemi cyangwa kuribwa mu nda
• Urubavu
• Inkorora

Ibi bimenyetso bigaragara bikunze gukira mu byumweru bike uko umubiri wawe wimenyereza umuti. Niba bikomeje cyangwa bikaba bibangamiye, ganira na muganga wawe ku bijyanye no guhindura urugero rw'umuti wawe cyangwa igihe uwufata.

Hariho kandi ibindi bimenyetso bitagaragara cyane ariko bikomeye bisaba ubufasha bwihuse bwa muganga:

• Kuribwa cyane cyangwa kugwa igihumure
• Ukubura mu maso, iminwa, ururimi, cyangwa umuhogo
• Kubura umwuka cyangwa kumeza
• Uruhu ruruka cyangwa imyatsi
• Umutima utera cyane cyangwa mu buryo butari bwo
• Urubavu rukabije
• Ibimenyetso by'ibibazo by'impyiko (imihindukire mu kunyara, kubura mu maguru cyangwa ibirenge)

Vugana n'umuganga wawe ako kanya niba ubonye izi ngaruka zikomeye. Nubwo bitaba kenshi, bishobora kwerekana igikorwa gikomeye gikeneye ubuvuzi bwihuse.

Ninde utagomba gufata Aliskiren?

Aliskiren ntikwiriye kuri buri wese, kandi ibibazo by'ubuzima runaka cyangwa ibihe bituma bidatekanye gukoreshwa. Muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kwandika uyu muti.

Ntugomba gufata aliskiren niba urwaye diyabete kandi unakoresha ACE inhibitors cyangwa ARBs (izindi miterere y'imiti igabanya umuvuduko w'amaraso). Ubu buryo bwongera cyane ibyago by'ibibazo bikomeye by'impyiko n'umuvuduko w'amaraso muke cyane.

Abantu barwaye indwara zikomeye z'impyiko cyangwa abari kuri diyalisisi bagomba kwirinda aliskiren, kuko bishobora gutuma imikorere y'impyiko irushaho kuba mibi. Mu buryo nk'ubwo, niba ufite amateka y'indwara ikomeye y'umwijima, uyu muti ntushobora kuba ukwiriye kuri wowe.

Abagore batwite ntibagomba na rimwe gufata aliskiren, kuko bishobora guteza ingaruka zikomeye ku mwana ukura, harimo ibibazo by'impyiko n'umuvuduko muke w'amaraso. Niba uteganya gutwita cyangwa ukavumbura ko utwite mugihe ufata aliskiren, vugana n'umuganga wawe ako kanya.

Ababyeyi bonka bagomba kandi kwirinda aliskiren, kuko ntibizwi niba uyu muti ujya mu mata kandi ushobora kugira ingaruka ku mwana wonka.

Amazina y'ubwoko bwa Aliskiren

Aliskiren iboneka munsi y'izina ry'ubwoko rya Tekturna muri Leta Zunze Ubumwe z'Amerika. Iyi ni yo miterere isanzwe yandikwa y'uyu muti kandi ni icyo ushobora kubona ku icupa ryawe ry'umuti.

Hari kandi umuti uvanga witwa Tekturna HCT, urimo aliskiren na hydrochlorothiazide (umuti utuma umubiri uvamo amazi). Uyu muti uvanga ukoreshwa iyo abarwayi bakeneye imiti yombi kugira ngo bagenzure neza umuvuduko w'amaraso yabo.

Imiti ya aliskiren idafite izina ry'ubucuruzi iraboneka kandi, irimo ibintu byose bikora kimwe ariko ishobora gutwara amafaranga make ugereranyije n'iyo ifite izina ry'ubucuruzi. Umufarimasi wanyu ashobora kubafasha gusobanukirwa niba umuti udafite izina ry'ubucuruzi ari wo ukwiriye kuri mwe.

Izindi miti isimbura Aliskiren

Niba aliskiren itakwiriye cyangwa idakora neza, hari izindi mbiti nyinshi zishobora gukoreshwa mu kugabanya umuvuduko w'amaraso. Muganga wawe ashobora kubafasha kubona umuti mwiza bitewe n'ibyo mukeneye n'amateka y'uburwayi bwanyu.

Imiti ya ACE nka lisinopril cyangwa enalapril akenshi ni imiti ikoreshwa bwa mbere mu kuvura umuvuduko w'amaraso. Ikora ibuza ikindi kintu mu nzira imwe na aliskiren ikoreramo, kandi abantu benshi barayihanganira neza.

ARBs (Angiotensin Receptor Blockers) nka losartan cyangwa valsartan itanga ubundi buryo. Iyi miti ibuza ingaruka za angiotensin II ku rwego rwa receptor kandi akenshi ntigira ingaruka nyinshi nk'imiti ya ACE.

Imiti ibuza calcium channel nka amlodipine cyangwa nifedipine ikora irekura imitsi y'amaraso hakoreshejwe uburyo butandukanye rwose. Ifasha cyane abantu bafite ibibazo by'umutima runaka.

Imiti ituma umubiri uvamo amazi (imiti ituma umubiri uvamo amazi) nka hydrochlorothiazide ifasha kugabanya umuvuduko w'amaraso igabanya amazi mu miyoboro y'amaraso. Akenshi ikoreshwa hamwe n'indi miti igabanya umuvuduko w'amaraso kugira ngo bigenzurwe neza.

Ese Aliskiren iruta Lisinopril?

Aliskiren na lisinopril ni imiti yombi igabanya umuvuduko w'amaraso, ariko ikora hakoreshejwe uburyo butandukanye kandi ifite ibyiza bitandukanye. Nta n'imwe iruta iyindi - guhitamo neza biterwa n'uburwayi bwanyu bwihariye n'uko mwitwara kuri buri muti.

Lisinopril ni umuti wa ACE inhibitor umaze imyaka myinshi ukoreshwa kandi ufite ubushakashatsi bwinshi bushyigikira imikorere yawo. Akenshi uhitwamo nk'umuti wa mbere wo kuvura kuko wizezwe, wihanganirwa neza, kandi uboneka mu buryo bwa rusange.

Aliskiren ishobora gukundwa niba waragize ingaruka ziterwa na ACE inhibitors nka lisinopril, cyane cyane inkorora ihoraho. Kubera ko aliskiren ikora hakiri kare mu nzira yo kugenzura umuvuduko w'amaraso, irashobora gukora neza kuri bamwe.

Ariko, lisinopril yagaragaje inyungu zirenze kugenzura umuvuduko w'amaraso, harimo kurengera abantu bafite umutima wanze gukora neza n'indwara ya diyabete ikomoka ku mpyiko. Aliskiren ntabwo ifite ubushakashatsi bwinshi bushyigikira izi nyungu zinyongera.

Muganga wawe azatekereza ibintu nk'izindi ndwara ufite, imiti ukoresha ubu, amateka y'ingaruka, n'ikiguzi mugihe afata icyemezo hagati y'izi mpuzamiti. Rimwe na rimwe kugerageza imiti yombi mugihe runaka bifasha kumenya iyikora neza kuri wowe.

Ibikunze Kubazwa Kuri Aliskiren

Ese Aliskiren irakwiriye abantu barwaye diyabete?

Aliskiren irashobora gukoreshwa neza kubantu barwaye diyabete, ariko hariho imbogamizi z'ingenzi. Niba urwaye diyabete, ntugomba gufata aliskiren hamwe na ACE inhibitors cyangwa ARBs, kuko iyi mpuzamiti yongera cyane ibyago byo kurwara impyiko no kugabanuka cyane k'umuvuduko w'amaraso.

Kubantu barwaye diyabete batarafata ACE inhibitors cyangwa ARBs, aliskiren irashobora kuba uburyo bwiza bwo kugenzura umuvuduko w'amaraso. Muganga wawe azagenzura imikorere y'impyiko zawe neza, kuko diyabete isanzwe ishyira igitutu ku mpyiko.

Ibizami by'amaraso bisanzwe byo kureba imikorere y'impyiko n'urugero rwa potasiyumu ni ngombwa cyane iyo ufite diyabete kandi ufata aliskiren. Ibi bifasha kumenya ibibazo byose bishoboka hakiri kare.

Nigute nakora niba mfashe aliskiren nyinshi bitunguranye?

Niba wanyoye aliskiren nyinshi kurusha uko wagombaga, vugana na muganga wawe cyangwa ikigo gishinzwe uburozi ako kanya, kabone n'iyo wumva umeze neza. Kunywa nyinshi bishobora gutera igabanuka ry'amaraso ry'uburyo bukomeye, rishobora kutagaragaza ibimenyetso ako kanya.

Ibimenyetso byo kunywa nyinshi bishobora kuba harimo isereri rikomeye, kugwa igihumure, isesemi, cyangwa kumva unaniwe cyane. Niba ubonye ibi bimenyetso, genda kwa muganga ako kanya.

Ntugerageze "gukemura" kunywa nyinshi ukoresheje kwirengagiza imiti yo mu gihe kizaza. Ahubwo, shakisha ubujyanama bwa muganga ku buryo bwo gusubukura neza gahunda yawe isanzwe yo kunywa imiti.

Nkwiriye gukora iki niba nirengagije urugero rwa Aliskiren?

Niba wirengagije urugero rwa aliskiren, nywe ako kanya wibukirije, keretse igihe cyo kunywa urugero rwawe rukurikira kigeze. Muri icyo gihe, irengagize urugero wirengagije ukomeze gahunda yawe isanzwe.

Ntunyweho urugero rurenze rumwe icyarimwe kugira ngo usimbure urugero wirengagije, kuko ibi bishobora gutera igabanuka ry'amaraso ryinshi cyane. Biruta kurengagiza urugero rumwe kurusha gushyira ubuzima bwawe mu kaga ko kunywa nyinshi.

Niba ukunda kwibagirwa urugero, gerageza gushyiraho alarume ya buri munsi cyangwa ukoreshe igikoresho gifasha kwibuka imiti kugira ngo bikufashe kwibuka. Kunywa imiti buri munsi ni ingenzi kugira ngo amaraso yawe agume mu rugero rwiza.

Nshobora guhagarika ryari kunywa Aliskiren?

Wagombye guhagarika kunywa aliskiren gusa ukurikije ubujyanama bwa muganga wawe, kabone n'iyo ibipimo by'amaraso yawe byateye imbere. Umuvuduko mwinshi w'amaraso akenshi ni indwara ihoraho isaba kuvurwa buri gihe kugira ngo wirinde ingorane.

Muganga wawe ashobora gutekereza kugabanya cyangwa guhagarika aliskiren niba wakoze impinduka zikomeye mu mibereho yawe zateje imbere ubuzima bwawe bw'umutima n'imitsi, nk'uko gutakaza ibiro byinshi, gukora imyitozo ngororamubiri buri gihe, cyangwa kunoza imirire.

Ntuzigere uhagarika kunywa aliskiren ako kanya, kuko ibi bishobora gutera amaraso yawe kuzamuka mu buryo bukomeye ku rwego rw'akaga. Niba impinduka ku miti yawe zikenewe, muganga wawe azakora gahunda yo guhindura buhoro buhoro uburyo bwawe bwo kuvurwa mu buryo bwizewe.

Nshobora kunywa inzoga nkanwa Aliskiren?

Nubwo inzoga ntoya zishobora kuba byiza, ni byiza kugabanya kunywa inzoga mugihe ufata aliskiren. Inzoga irashobora kongera ingaruka zo kugabanya umuvuduko w'amaraso z'umuti, bishobora gutera isereri cyangwa kugabanuka kw'umuvuduko w'amaraso ku buryo buteye akaga.

Niba unywa inzoga, bikore mu rugero ruto kandi witondere uko wumva. Witondere cyane iyo uhagurutse, kuko guhuza aliskiren n'inzoga bishobora kongera ibyago byo kugira isereri cyangwa guta ubwenge.

Ganira na muganga wawe ku rwego rwo kunywa inzoga, niba hari urwo arwo, ruri kuri wewe mugihe ufata aliskiren. Bashobora gutanga ubujyanama bwihariye bushingiye ku buzima bwawe muri rusange n'indi miti ushobora kuba ufata.