Icyo Amitriptyline ari cyo: Ibyo ikoreshwa, urugero rwa dose, ingaruka ziterwa n'iyo miti n'ibindi

Amitriptyline ni umuti wandikirwa na muganga wo mu itsinda ry'imiti yitwa tricyclic antidepressants. Nubwo yabanje gukorwa kugira ngo ivure umubabaro, abaganga ubu bakoresha cyane ibintu bitandukanye birimo kubabara kw'igihe kirekire, migraine, n'indwara zo gusinzira. Uyu muti ukora mu buryo butandukanye ukora ku binyabutabazi bimwe na bimwe mu bwonko bwawe no mu mikorere y'imitsi, ibyo bishobora gufasha kunoza imyumvire no kugabanya ibimenyetso by'ububabare.

Icyo Amitriptyline ari cyo?

Amitriptyline ni tricyclic antidepressant imaze imyaka myinshi ikoreshwa mu buryo bwizewe mu kuvura indwara nyinshi. Iza mu buryo bw'ibinini bifatirwa mu kanwa, akenshi rimwe ku munsi mbere yo kuryama. Uyu muti ukora mu kongera urwego rw'ibinyabutabazi bimwe na bimwe mu bwonko bwawe, cyane cyane serotonin na norepinephrine, bifite uruhare runini mu kugenga imyumvire no kumva ububabare.

Uyu muti ufatwa nk'umuti ufite imbaraga ziringaniye mu miti ivura umubabaro. Muganga wawe azagutangiza ku rugero ruto kandi ashobora kuruzamura buhoro buhoro bitewe n'uko witwara n'icyo urimo kuvurwa.

Amitriptyline ikoreshwa mu kuvura iki?

Amitriptyline ivura indwara zitandukanye, nubwo muganga wawe azayandika bitewe n'ibyo ukeneye. Ibikoreshwa cyane birimo umubabaro, indwara z'ububabare bw'igihe kirekire, no gukumira migraine.

Dore indwara nyamukuru amitriptyline ifasha:

• Umubabaro n'indwara zo mu mutwe
• Indwara z'ububabare bw'igihe kirekire nka fibromyalgia n'ububabare bwa neuropathic
• Gukumira kubabara umutwe kwa migraine
• Kubabara umutwe bitewe no guhagarika umutima
• Indwara zo gusinzira no kutabona ibitotsi
• Irritable bowel syndrome (IBS)

Mu buryo butajyenda cyane, abaganga bashobora kwandikira amitriptyline ku bibazo byo guhangayika, indwara yo guhangayika nyuma y'ihungabana (PTSD), cyangwa indwara zimwe na zimwe zo kurya. Umuganga wawe azagena niba uyu muti ukwiriye kuri wowe.

Amitriptyline ikora ite?

Amitriptyline ikora ibuza kongera gufatwa kwa serotonin na norepinephrine mu bwonko bwawe. Bitekerezeho nk'ubutumwa bwa chimique bufasha selile z'imitsi kuvugana. Iyo amitriptyline ibuza iyi mishonga gusubizwa muri selile z'imitsi, yongera uko iboneka mu bwonko bwawe.

Uku kongera kuboneka kwa neurotransmitters bishobora gufasha kunoza imyumvire yawe niba urwaye depression. Ku bibazo by'ububabare, amitriptyline ihindura uburyo ibimenyetso by'ububabare bigenda mu mikorere y'imitsi yawe, bigatuma bitagira imbaraga nyinshi. Uyu muti kandi ufite ingaruka zo gutuza, niyo mpamvu akenshi ufashwa nijoro kandi ushobora gufasha mu bibazo byo gusinzira.

Ni ngombwa gusobanukirwa ko amitriptyline itinda gukora. Ushobora gukenera kuyifata mu byumweru byinshi mbere yo kubona inyungu zayo zose, cyane cyane kuri depression cyangwa ibibazo by'ububabare buhoraho.

Nkwiriye gufata amitriptyline nte?

Fata amitriptyline nkuko umuganga wawe abitegeka, akenshi rimwe ku munsi nijoro. Uyu muti ushobora gutuma uba umunebwe, bityo kuwufata mbere yo gusinzira bifasha kugabanya umunebwe wo ku manywa mugihe bishobora kunoza imikorere yawe yo gusinzira.

Ushobora gufata amitriptyline hamwe cyangwa udafashije, ariko kuyifata hamwe n'akantu gato cyangwa ifunguro rishobora gufasha kugabanya indwara zo munda. Mimina ikinini cyose hamwe n'ikirahure cyuzuye cy'amazi. Ntugasenye, utahe cyangwa ucagagure ikinini keretse umuganga wawe akubwiye kubikora.

Gerageza gufata umuti wawe mu gihe kimwe buri mugoroba kugirango ufashishe umubiri wawe kumenyera gahunda. Niba utangiye gufata amitriptyline, umuganga wawe ashobora gutangira n'urugero ruto hanyuma akagenda arwongera buhoro buhoro mu byumweru byinshi kugirango abone urugero rukwiriye kuri wowe.

Nshobora Kumara Igihe Kingana Giki Ndafata Amitriptyline?

Igihe cyo gufata amitriptyline gitandukana cyane bitewe n'uburwayi ufite n'uburyo umubiri wawe wakira imiti. Ku bijyanye no kwiheba, ushobora gukenera kuyifata byibura amezi atandatu kugeza ku mwaka nyuma y'uko ibimenyetso byawe bigabanuka kugira ngo wirinde kongera kugaragaza ibimenyetso by'uburwayi.

Niba ukoresha amitriptyline kugira ngo uvure uburibwe buhoraho cyangwa kwirinda migraine, ushobora gukenera kuyifata amezi menshi cyangwa se igihe kirekire. Abantu bamwe basanga kuyikoresha igihe kirekire bifasha mu guhangana n'indwara zihoraho. Muganga wawe azagenzura buri gihe uko urimo uritwara kandi ashobora guhindura gahunda yawe yo kuvurwa uko bikwiye.

Ntuzigere uhagarika gufata amitriptyline ako kanya, n'iyo wumva umeze neza. Kuyihagarika ako kanya bishobora gutera ibimenyetso byo kuva mu miti nk'isazi, isesemi, kubabara umutwe, n'ibimenyetso bisa n'ibicurane. Muganga wawe azagufasha kugabanya buhoro buhoro urugero rw'umuti igihe kigeze cyo guhagarika imiti.

Ni Iyihe Mbere Y'ingaruka Ziterwa na Amitriptyline?

Kimwe n'indi miti yose, amitriptyline ishobora gutera ingaruka ziterwa n'imiti, nubwo atari buri wese uzihura. Ingaruka nyinshi ziterwa n'imiti zoroheje kandi akenshi zigenda zikemuka uko umubiri wawe wimenyereza imiti mu byumweru bike bya mbere.

Ingaruka zisanzwe ushobora guhura nazo zirimo:

• Gusinzira cyane cyangwa gutuza
• Umunwa wumye
• Kugugara
• Kureba nabi
• Kongera ibiro
• Isazi, cyane cyane iyo uhagurutse
• Kugorana kwihagarika

Izi ngaruka mubisanzwe zirashoboka kandi zikunda kugabanuka uko igihe kigenda. Kunywa amazi menshi, kurya ibiryo birimo fibre nyinshi, no guhaguruka buhoro buhoro uva mu mwanya wo kwicara cyangwa kuryama bishobora gufasha kugabanya zimwe muri izi mpungenge.

Ingaruka zikomeye ntizisanzwe ariko zisaba ubufasha bwihuse bwa muganga. Vugana na muganga wawe ako kanya niba uhuye n'umutima utera nabi, isazi ikabije, urujijo, kuva amaraso cyangwa gukomeretsa bidasanzwe, cyangwa ibimenyetso by'ibibazo by'umwijima nk'uruhu cyangwa amaso by'umuhondo.

Niba ufata amitriptyline kubera depression, menya ko abantu bamwe, cyane cyane abari munsi y'imyaka 25, bashobora kugira ibitekerezo byinshi byo kwiyahura igihe batangira gufata uyu muti. Iyi ngaruka ni nini cyane mu byumweru bike bya mbere by'ubuvuzi, bityo ugomba kugumana umubano wa hafi n'umuganga wawe mugihe cyose.

Ninde utagomba gufata Amitriptyline?

Amitriptyline ntabwo ikwiriye kuri buri wese, kandi muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuyandika. Indwara zimwe na zimwe n'imiti irashobora gutuma amitriptyline itaba nziza cyangwa idakora neza.

Ntabwo ugomba gufata amitriptyline niba umaze iminsi mike ugize umutima, ufite ibibazo bimwe na bimwe by'umutima, cyangwa ufata MAO inhibitors (ubwoko bwa antidepressant). Abantu bafite glaucoma ya narrow-angle, guhagarika inkari bikabije, cyangwa allergie zizwi kuri tricyclic antidepressants nabo bagomba kwirinda uyu muti.

Muganga wawe azakoresha ubushishozi bwinshi niba ufite indwara y'umutima, ibibazo by'umwijima cyangwa impyiko, indwara zo gufatwa, indwara ya bipolar, cyangwa amateka y'ibitekerezo byo kwiyahura. Abantu bakuze bashobora kumva cyane ingaruka ziterwa n'uyu muti kandi bashobora gukenera doze ntoya cyangwa gukurikiranwa kenshi.

Niba utwite cyangwa wonka, ganira ku ngaruka n'inyungu n'umuganga wawe. Nubwo amitriptyline ishobora gukoreshwa mugihe cyo gutwita mugihe bibaye ngombwa, yinjira mu mata kandi ishobora kugira ingaruka ku mwana wonka.

Amazina y'ubwoko bwa Amitriptyline

Amitriptyline iboneka munsi y'amazina menshi y'ubwoko, nubwo verisiyo rusange ikoreshwa cyane. Muri Leta Zunze Ubumwe z'Amerika, urashobora kubona yagurishwa nka Elavil, nubwo iri zina ry'ubwoko ritarimo gukoreshwa cyane ubu.

Amavuriro menshi afite verisiyo rusange ya amitriptyline, irimo ibintu bikora kimwe kandi ikora neza kimwe na verisiyo y'amazina y'ubwoko. Imiti rusange akenshi ihendutse kandi igenzurwa n'amabwiriza amwe yo gukoresha nk'imiti y'amazina y'ubwoko.

Icyuma cyo kuvuriraho imiti yawe kizerekana neza niba urimo guhabwa amitriptyline isanzwe cyangwa ubwoko bw'izina ry'uruganda. Niba ufite impungenge zo guhindura hagati y'ubwoko busanzwe n'ubwoko bw'izina ry'uruganda, ganira ibi na farumasiye cyangwa muganga wawe.

Uburyo bwo gusimbuza Amitriptyline

Imiti myinshi isimbura irashobora kuvura indwara zimwe na zimwe nka amitriptyline, nubwo guhitamo neza biterwa n'uko ubuzima bwawe bumeze n'uko witwara ku miti itandukanye. Muganga wawe ashobora gutekereza izindi nzira niba amitriptyline itagukundiye cyangwa ikagutera ingaruka mbi.

Kubijyanye no kwiheba, ibisubizo birimo izindi miti ivura kwiheba nka nortriptyline cyangwa desipramine, bishobora gutera ingaruka nke. Imiti mishya ivura kwiheba nka SSRIs (ibintu bitoranya byongera serotonin) nka sertraline cyangwa fluoxetine nabyo ni amahitamo.

Niba ukoresha amitriptyline kubera ububabare buhoraho, ibisubizo bishobora kuba gabapentin, pregabalin, cyangwa duloxetine. Kubijyanye no gukumira migraine, muganga wawe ashobora gutanga topiramate, propranolol, cyangwa imiti mishya yihariye ya migraine.

Umutuzo wo guhindura imiti ugomba gukorwa buri gihe hamwe n'umuganga wawe, ushobora kugufasha gupima inyungu n'ibibazo by'uburyo bwo kuvura butandukanye bushingiye ku byo ukeneye.

Ese Amitriptyline iruta Nortriptyline?

Amitriptyline na nortriptyline zombi ni imiti ivura kwiheba ikora kimwe, ariko ifite itandukaniro rikomeye. Nortriptyline ni metaboliti ya amitriptyline, bivuze ko umubiri wawe uhindura amitriptyline muri nortriptyline.

Nortriptyline muri rusange itera ingaruka nke kurusha amitriptyline, cyane cyane kutagira umutuzo, umunwa wumye, no kongera ibiro. Ibi bituma nortriptyline iba amahitamo meza kubantu bafite ubwumvikane ku ngaruka cyangwa bakeneye kuguma maso kumanywa.

Ariko, ingaruka zo gutuza za amitriptyline zirashobora kugira akamaro niba ufite ibibazo byo gusinzira hamwe n'izindi ndwara ufite. Guhitamo hagati y'iyo miti biterwa n'ibimenyetso byawe byihariye, kwihanganira ingaruka ziterwa n'imiti, n'intego zo kuvura.

Muganga wawe azatekereza ibintu nk'imyaka yawe, izindi ndwara, n'uburyo wari warakiriye imiti mbere yo gufata icyemezo hagati ya amitriptyline na nortriptyline. Iyo miti yombi irakora, kandi guhitamo "neza" ni kimwe gikora neza ku miterere yawe.

Ibikunze Kubazwa Kuri Amitriptyline

Ese Amitriptyline irakwiriye indwara z'umutima?

Amitriptyline bisaba kwitondera cyane niba ufite indwara z'umutima, kuko ishobora kugira ingaruka ku mutima wawe n'umuvuduko w'amaraso. Uwo muti ushobora gutera impinduka mu mikorere y'amashanyarazi y'umutima wawe, bishobora kuba bibi ku bantu bafite indwara z'umutima zimwe na zimwe.

Niba ufite indwara z'umutima, muganga wawe ashobora gutegeka gukora electrocardiogram (ECG) mbere yo gutangira amitriptyline kandi ashobora gukurikirana imikorere y'umutima wawe buri gihe. Bashobora guhitamo urugero ruto cyangwa bagasaba undi muti utagira ingaruka ku mutima wawe.

Ntuzatangire cyangwa uhagarike amitriptyline utabanje kubaza muganga wawe niba ufite ibibazo by'umutima. Inyungu zo kuvurwa zirashobora kurenga ibyago mu bihe byinshi, ariko icyemezo nk'iki gisaba kugenzurwa na muganga.

Nigute nzakora niba nanyoye amitriptyline nyinshi bitunguranye?

Niba unyoye amitriptyline nyinshi bitunguranye, shakisha ubufasha bwihuse bwa muganga uhamagara serivisi zihutirwa cyangwa ujye mu cyumba cyihutirwa cyegereye. Kwiyongera kwa amitriptyline birashobora kuba bikomeye kandi bishobora gushyira ubuzima mu kaga.

Ibimenyetso byo kwiyongera kwa amitriptyline birimo gusinzira cyane, urujijo, umutima utagenda neza, guhumeka bigoye, gufatwa, cyangwa gutakaza ubwenge. Ntukategere kureba niba ibimenyetso bigaragara - shakisha ubufasha ako kanya niba unyoye doze irenze iyagutanzwe.

Kugira ngo wirinde kunywa imiti irenze urugero, bika imiti yawe mu gikoresho cyayo cy'umwimerere ifite ibirango bisobanutse, kandi ushobora gukoresha agasanduku ko gushyiramo imiti niba ufata imiti myinshi. Niba ugira ikibazo cyo kwibuka niba wamaze gufata urugero rwawe, baza umufarimasi w'imiti yawe kuri gahunda zo kwibutsa.

Nkwiriye gukora iki niba nciwe urugero rwa Amitriptyline?

Niba ucikanwe urugero rwawe rwa nimugoroba rwa amitriptyline, uyifate uko ubibutse vuba, keretse igihe cyo gufata urugero rwawe ruteganyijwe kigeze. Ntukagire urugero rurenzeho kugira ngo usubize urwo waciwe, kuko ibyo bishobora kongera ibyago byo kugira ingaruka zidakurikira.

Niba wibuka urugero waciwe mu gitondo, mubisanzwe ni byiza kurwica hanyuma ugasubira kuri gahunda yawe isanzwe nimugoroba. Gufata amitriptyline ku manywa bishobora gutera gusinzira cyane kandi bigahungabanya ubushobozi bwawe bwo gukora neza.

Niba ukunda kwibagirwa urugero, ganira na muganga wawe cyangwa umufarimasi ku bijyanye n'uburyo bwo kugufasha kwibuka. Gushyiraho alarme yo kuryama cyangwa gukoresha porogaramu yo kwibutsa imiti birashobora kuba ibikoresho bifasha mu kubungabunga gahunda yawe.

Nshobora guhagarika ryari gufata Amitriptyline?

Umwanzuro wo guhagarika amitriptyline ugomba gufatwa buri gihe hamwe n'ubuyobozi bwa muganga wawe, kuko igihe biterwa n'uburwayi bwawe n'uburyo wabyitwayemo ku buvuzi. Kubijyanye no kwiheba, mubisanzwe uzakenera gukomeza imiti byibuze amezi atandatu nyuma yuko ibimenyetso byawe bigabanuka.

Niba ukoresha amitriptyline kubera kubabara kw'igihe kirekire cyangwa gukumira migraine, ushobora gukenera kuvurwa igihe kirekire. Abantu bamwe bungukirwa no kuyifata imyaka myinshi, mu gihe abandi bashobora kugabanya buhoro urugero rwabo nyuma yuko uburwayi bwabo buhamye.

Igihe kigeze cyo guhagarika, muganga wawe azakora gahunda yo kugabanya buhoro kugira ngo agabanye buhoro urugero rwawe mu byumweru byinshi cyangwa amezi. Ibi bifasha kwirinda ibimenyetso byo gukurwaho kandi bituma umubiri wawe wimenyereza buhoro gukora udafite imiti.

Nshobora kunywa inzoga niba mfata Amitriptyline?

Ni byiza kwirinda inzoga igihe urimo gufata amitriptyline, kuko ibintu byombi bishobora gutera gusinzira no guhagarika imikorere y'ubwonko. Kubihuza bishobora kongera cyane ibi bintu, bigatuma usinzira cyane kandi bikaba byagira ingaruka ku mikoranire yawe n'ubushishozi.

Inzoga kandi ishobora gutuma ibimenyetso byo kwiheba no guhangayika birushaho kuba bibi, bikaba bishobora kubangamira iterambere ryawe mu kuvurwa. Niba urimo gufata amitriptyline kubera kwiheba, gukoresha inzoga bishobora gutuma bigorana kugera ku mpinduka z'imitekerereze urimo gushaka.

Niba uhisemo kunywa inzoga rimwe na rimwe, wikwiriza gukoresha gake kandi umenye uko uruvange rugira ingaruka kuri wowe. Ntukigere utwara imodoka cyangwa ukoresha imashini niba unyweye inzoga urimo gufata amitriptyline, kandi uvugane n'umuganga wawe ku bijyanye no gukoresha inzoga ku mugaragaro.