Baclofen ni iki: Ibikoreshwa, Uburyo bwo gukoresha, Ingaruka ziterwa n'ibindi

Baclofen ni umuti w'imitsi ufasha kugabanya imitsi yikanyaga no gukakara. Ukora utuma ibimenyetso by'imitsi bikabije mu mugongo wawe bituma imitsi yikanyaga ku buryo butunguranye. Uyu muti wandikirwa na muganga ushobora gufasha cyane abantu bahanganye n'indwara nka multiple sclerosis, imvune zo mu mugongo, cyangwa cerebral palsy.

Baclofen ni iki?

Baclofen ni umuti wandikirwa na muganga ugabanya imitsi, ukaba mu cyiciro cy'imiti yitwa gamma-aminobutyric acid (GABA) agonists. Yigana imisemburo kamere yo mu bwonko yitwa GABA, ifasha kugabanya imikorere y'imitsi mu mubiri wawe. Utekereze nk'uburyo bwo guhagarika buhoro buhoro imitsi yawe ikabije.

Uyu muti wabanje gukorwa mu myaka ya za 1960 kandi umaze imyaka myinshi ufasha abantu gucunga imitsi yikanyaga. Ufatwa nk'uburyo bwizewe kandi bwizweho bwo kuvura, abaganga bakunze gukoresha iyo imitsi yikanyaga ibangamiye imirimo ya buri munsi cyangwa itera kutumva neza.

Baclofen ikoreshwa mu kuvura iki?

Baclofen ahanini yandikirwa kuvura imitsi yikanyaga, ni ukuvuga igihe imitsi yawe yikanyaga cyangwa igakakara ku buryo butunguranye. Iyi mitsi yikanyaga ishobora gutuma kugenda bigorana kandi bikababaza, bigatuma udashobora kugenda, kwandika, cyangwa gukora imirimo ya buri munsi.

Indwara zisanzwe baclofen ifasha kuvura zirimo multiple sclerosis, imvune zo mu mugongo, na cerebral palsy. Ikoreshwa kandi mu kuvura imvune zo mu bwonko ziterwa n'impanuka, gukira nyuma ya stroke, n'indwara zimwe na zimwe ziterwa n'imiterere y'umubiri zigira ingaruka ku micungire y'imitsi. Muganga wawe ashobora kukwandikira uyu muti niba ufite imitsi yakakaye, imitsi yikanyaga ibabaza, cyangwa ugorwa no kugenda kubera indwara zo mu bwonko.

Abaganga bamwe na bamwe banandika baclofen ku buryo butemewe mu kuvura indwara nka gukurwaho kwa alukolo cyangwa ubwoko bumwe na bumwe bw'uburibwe buhoraho. Ariko, izi nshingano zisaba ubugenzuzi bw'ubuvuzi bwitondewe kandi ntabwo ari zo mpamvu nyamukuru uyu muti watejwe imbere.

Ni gute Baclofen ikora?

Baclofen ikora yibanda ku byakira byihariye mu mugongo wawe no mu bwonko byitwa GABA-B receptors. Iyo yifatanyije n'ibi byakira, igabanya irekurwa ry'imirasire y'ubwonko itera imitsi gukomera. Ibi bitera ingaruka zo gutuza ku mikoranire y'imitsi yawe.

Uyu muti ufatwa nk'ukomeye ku rugero rwo hagati mu miti igabanya imitsi. Ufite intego kurusha imiti imwe isanzwe igabanya imitsi kuko ikora byihariye ku mikoranire y'imitsi yo hagati aho gukora ku gice cy'imitsi ku buryo butaziguye. Ibi bituma bikora neza cyane ku gukomera kw'imitsi guterwa n'indwara zo mu bwonko.

Muri rusange, uzatangira kumva ingaruka nyuma y'amasaha make umaze gufata urugero rwa mbere. Ariko, bishobora gufata iminsi cyangwa ibyumweru kugira ngo ubone urugero rukwiye rutanga ubufasha bwiza hamwe n'ingaruka nke. Umubiri wawe uhoro gahoro wimenyereza uyu muti, niyo mpamvu impinduka z'urugero zikunze gukorwa buhoro.

Nkwiriye gufata Baclofen nte?

Fata baclofen nk'uko byategetswe na muganga wawe, akenshi gatatu ku munsi hamwe cyangwa hatariho ibiryo. Urashobora kuyifata hamwe n'amata cyangwa ifunguro rito niba bituma urwara mu nda. Uyu muti uza mu buryo bw'ibinini kandi ugomba kumirwa wose hamwe n'ikirahure cyuzuye cy'amazi.

Abantu benshi batangira ku rugero ruto, akenshi 5mg gatatu ku munsi, hanyuma bakagenda barwanya uko bikwiye. Muganga wawe ashobora kongera urugero rwawe buri minsi mike kugeza ubonye uburinganire bukwiye bwo kugabanya ibimenyetso n'ingaruka zishoboka. Urugero ntarengwa rwa buri munsi akenshi ni nka 80mg, ariko abantu bamwe bashobora gukenera urugero rurenzeho mu gihe cyo kugenzurwa na muganga.

Gerageza gufata urugero rwawe mu gihe kimwe buri munsi kugira ngo ugumane urugero ruhamye mu mubiri wawe. Niba uyifata gatatu ku munsi, gabanura urugero mu buryo bungana umunsi wose. Kuyifata hamwe n'ibiryo birashobora gufasha kugabanya uburibwe mu nda, ariko ntibikenewe rwose kugira ngo umuti ukore neza.

Nkwiriye gufata Baclofen igihe kingana iki?

Uburyo bwo kuvura na baclofen butandukanye cyane bitewe n'uburwayi bwawe n'uburyo umubiri wawe ubyakira. Abantu bamwe barabukenera mu byumweru bike mu gihe cyo gukira nyuma yo kuvunika, mu gihe abandi bashobora kubufata mu mezi cyangwa imyaka kugira ngo bafate ku burwayi burambye.

Niba ukoresha baclofen ku burwayi bw'igihe gito nk'imitsi yikora nyuma yo kubagwa, ushobora kubukenera mu byumweru bike gusa. Ariko, abantu bafite indwara zirambye nka multiple sclerosis cyangwa imvune zo mu mugongo akenshi babufata igihe kirekire nk'igice cy'uburyo bwo kuvurwa buri gihe.

Muganga wawe azagenzura buri gihe uko urimo uritwara kandi ashobora guhindura urugero rwawe cyangwa akaganira niba ukikeneye umuti. Ntukigere uhagarika gufata baclofen ako kanya, cyane cyane niba umaze iminsi myinshi uyafata. Guhagarika ako kanya bishobora gutera ibimenyetso byo kuva mu muti biteye akaga harimo no gufatwa n'ibihungabanyo, bityo muganga wawe azakora gahunda yo kugabanya buhoro buhoro niba ukeneye kubihagarika.

Ni izihe ngaruka ziterwa na Baclofen?

Kimwe n'imiti yose, baclofen ishobora gutera ingaruka, nubwo abantu benshi bayihanganira neza. Ingaruka zisanzwe zikunze kuba zoroshye kandi akenshi zikagenda zikemuka uko umubiri wawe wimenyereza umuti mu byumweru bike bya mbere.

Dore ingaruka zikunze kuvugwa ko ushobora guhura nazo:

• Gusinzira cyane cyangwa kunanirwa
• Kuribwa umutwe cyangwa kumva umutwe utameze neza
• Kugira intege nke cyangwa intege nke z'imitsi
• Kuruka cyangwa kuribwa mu nda
• Kuribwa umutwe
• Kugorana kw'igifu
• Kudatekana mu gusinzira cyangwa kutagira ibitotsi

Izi ngaruka zisanzwe akenshi zigenda zigaragara cyane uko umubiri wawe umenyera umuti. Abantu benshi basanga gutangira ku rugero ruto no kongera buhoro buhoro bifasha kugabanya izi ngaruka.

Ingaruka zikomeye ziterwa n'imiti ntizikunze kubaho ariko zisaba ubufasha bwihutirwa bw'abaganga. Zishobora kuba zirimo ibimenyetso bikomeye byo kwibasirwa n'umubiri, urujijo, kwibeshya, cyangwa kugorwa no guhumeka. Abantu bamwe bashobora guhindura imyumvire, kwiheba, cyangwa gutekereza ibintu bidasanzwe, cyane cyane iyo bafashe imiti myinshi.

Ingaruka zikomeye ariko zitabaho kenshi zirimo ibibazo by'umwijima, kunanuka gukabije kw'imitsi bigira ingaruka ku guhumeka, cyangwa gufatwa n'ibihungabanyo (cyane cyane iyo uhagaritse gufata umuti mu buryo butunguranye). Niba wumva ububabare mu gituza, umutima utera cyane, kuribwa cyane, cyangwa ibimenyetso byo kwibasirwa n'umubiri nk'uruhu rurya cyangwa kubyimba, vugana n'umuganga wawe ako kanya.

Ninde utagomba gufata Baclofen?

Baclofen ntabwo ikwiriye kuri buri wese, kandi ibibazo bimwe na bimwe cyangwa ibihe byatuma bishobora kuba byateza akaga. Umuganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kugusaba uyu muti.

Ntugomba gufata baclofen niba ufite allergie izwi kuri uyu muti cyangwa ibikoresho byawo. Abantu bafite indwara zikomeye z'impyiko bakeneye guhindura imiti cyangwa ntibashobore kuyifata na gato, kuko umuti ukurwa mu mubiri unyuze mu mpyiko.

Ubwitange bwihariye bukenewe ku bantu bafite amateka y'ibihungabanyo, ibibazo byo mu mutwe, cyangwa gukoresha ibiyobyabwenge. Uyu muti ushobora kugabanya ubushobozi bwo gufatwa n'ibihungabanyo kandi ushobora gutuma kwiheba cyangwa guhangayika bikomera ku bantu bamwe na bamwe. Abantu bafite indwara z'umwijima nabo bakeneye gukurikiranwa neza, kuko uyu muti ushobora kugira ingaruka ku mikorere y'umwijima.

Abagore batwite kandi bonka bagomba kuganira ku byiza n'ibibi n'umuganga wabo. Nubwo baclofen ishobora kwinjira mu mata y'ibere, icyemezo cyo kuyikoresha mu gihe cyo gutwita cyangwa konka giterwa niba inyungu ziruta ibyago bishobora guteza umwana.

Abantu bakuze bashobora kugaragaza ibimenyetso byinshi bya baclofen, cyane cyane gusinzira no kuyoba. Akenshi bakeneye imiti mike kandi bakagenzurwa kenshi kugirango birinde kugwa cyangwa izindi ngorane.

Amazina y'ubwoko bwa Baclofen

Baclofen iboneka mu mazina menshi y'ubucuruzi, nubwo verisiyo rusange ikoreshwa cyane. Izina ry'ubucuruzi rizwi cyane ni Lioresal, ryari izina ry'umwimerere igihe umuti wabanje gutangizwa.

Andi mazina y'ubucuruzi arimo Gablofen na Kemstro, nubwo aya ataboneka mu bihugu byose. Kemstro ni tablet idasanzwe isenyuka mu kanwa, isenyukira ku rurimi rwawe, ibi bishobora gufasha abantu bagorwa no kumira ibinini.

Verisiyo rusange ya baclofen ifite akamaro kimwe na verisiyo z'amazina y'ubucuruzi kandi akenshi iraboneka cyane. Farumasi yawe ishobora guhita ishyiraho verisiyo rusange keretse muganga wawe asabye by'umwihariko izina ry'ubucuruzi.

Uburyo bwo gusimbuza Baclofen

Niba baclofen itagukundiye cyangwa ikaba itera ingaruka zikomeye, imiti myinshi isimbura ishobora kuvura imitsi yagurumanye. Guhitamo igisimbura biterwa n'uburwayi bwawe bwihariye, indi miti urimo gufata, n'uburyo wabyakiriye.

Tizanidine ni undi muti woroshya imitsi ukora mu buryo butandukanye na baclofen kandi ushobora kwihanganirwa neza n'abantu bamwe. Ifite akamaro cyane ku mitsi yagurumanye kandi ikoreshwa kenshi mu ndwara nka multiple sclerosis cyangwa imvune zo mu mugongo.

Diazepam, benzodiazepine, nayo irashobora gufasha ku mitsi yagurumanye ariko ifite ibyago byinshi byo kwishingikiriza no gukanguka. Akenshi ikoreshwa mu gihe gito cyangwa mu bihe byihariye aho indi miti itagize icyo ikora.

Uburyo butari ubw'imiti burimo kuvura umubiri, kuvura akazi, n'uburyo butandukanye bwo guterwa inshinge. Inshinge za botulinum toxin zirashobora kugira akamaro kanini ku mitsi yagurumanye, mugihe pompe za intrathecal baclofen zitanga umuti mu mazi yo mu mugongo kubantu bafite ibibazo bikomeye.

Ese Baclofen iruta Tizanidine?

Zose baclofen na tizanidine ni imiti ifasha koroshya imitsi, ariko zikora mu buryo butandukanye kandi zishobora gukwira neza abantu batandukanye. Guhitamo hagati yazo biterwa n'uburwayi bwawe bwihariye, ibindi bibazo by'ubuzima, n'uko witwara kuri buri muti.

Baclofen ikunda gukora neza ku gukomera kw'imitsi guterwa n'ibibazo byo mu mugongo, mugihe tizanidine ishobora gukora neza ku gukomera kw'imitsi bifitanye isano n'imvune zo mu bwonko cyangwa ibindi bibazo by'imitsi. Tizanidine akenshi ikundwa iyo gusinzira ari ikibazo gikomeye, kuko ishobora gutera gusinzira guke kurusha baclofen ku bantu bamwe.

Ingengabihe yo gufata imiti nayo iratandukanye. Baclofen akenshi ifatwa gatatu ku munsi, mugihe tizanidine ishobora gufatwa buri masaha atandatu cyangwa umunani. Abantu bamwe basanga ingengabihe imwe yoroshye kurusha iyindi bitewe n'imikorere yabo ya buri munsi.

Muganga wawe azatekereza ibintu nk'imikorere y'impyiko zawe, indi miti urimo gufata, n'imibereho yawe ya buri munsi mugihe afata icyemezo hagati y'izi mpuzangirangiriro. Rimwe na rimwe, abantu bagerageza imiti yombi mu bihe bitandukanye kugirango barebe iyikora neza kubibazo byabo byihariye.

Ibikunze Kubazwa Kuri Baclofen

Ese Baclofen irakwiriye abantu barwaye indwara y'impyiko?

Baclofen isaba guhindura doze ku bantu barwaye indwara y'impyiko kuko umuti uvanywamo binyuze mu mpyiko. Niba impyiko zawe zitagikora neza, umuti ushobora kwiyongera mu mubiri wawe ugatera ibindi bibazo byinshi.

Muganga wawe ashobora gutuma bakora ibizamini by'amaraso kugirango barebe imikorere y'impyiko zawe mbere yo gutangira baclofen kandi ashobora gukomeza kubikurikirana mugihe urimo kuyifata. Abantu bafite ibibazo byoroheje by'impyiko akenshi bashobora gufata baclofen neza hamwe na doze igabanutse, mugihe abafite indwara zikomeye z'impyiko bashobora gukenera gutekereza ku zindi miti.

Nigute nakora niba mfatanye na baclofen nyinshi?

Niba wanyoye baclofen nyinshi kurusha uko wagombaga, vugana na muganga wawe cyangwa ikigo gishinzwe ubumara ako kanya. Kunywa baclofen nyinshi bishobora gutera ibimenyetso by'akaga birimo gusinzira cyane, urujijo, kugorana guhumeka, cyangwa ndetse na koma.

Ntugerageze kwivugisha cyangwa gufata imiti yindi yo kurwanya ubwinshi bwa dose. Ahubwo, shakisha ubufasha bw'ubuvuzi ako kanya. Niba umuntu atazi ibyo arimo, afite ikibazo cyo guhumeka, cyangwa agaragaza ibimenyetso by'ubwinshi bwa dose bukomeye, hamagara serivisi z'ubutabazi ako kanya.

Nkwiriye gukora iki niba nciwe dose ya Baclofen?

Niba waciwe dose ya baclofen, yifate ako kanya wibuka, keretse igihe cyo gufata dose yawe ikurikira kigeze. Muri urwo rubanza, reka dose waciwe hanyuma ufate dose yawe ikurikira ku gihe gisanzwe.

Ntuzigere ufata dose ebyiri kugirango wuzuze iyo waciwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'imiti. Niba ukunda kwibagirwa dose, tekereza gushyiraho ibyibutso kuri terefone cyangwa gukoresha umuteguro w'ibinini kugirango bigufashe kuguma ku murongo w'igihe cyo gufata imiti yawe.

Nshobora kureka gufata Baclofen ryari?

Ugomba kureka gufata baclofen gusa ukurikije ubuyobozi bwa muganga wawe, cyane cyane niba umaze kuyifata mu byumweru birenga bike. Guhagarara ako kanya bishobora gutera ibimenyetso byo gukurwaho by'akaga birimo gufatwa n'indwara, kwibeshya, no gufatwa n'imitsi bikomeye.

Muganga wawe azakora gahunda yo kugabanya buhoro buhoro igabanya dose yawe mu minsi mike cyangwa mu byumweru. Ibi bituma umubiri wawe wimenyereza neza kugabanuka kw'imiti. Uburyo bwo kugabanya bushobora gutwara igihe kirekire niba umaze gufata dose nyinshi cyangwa ukoresha imiti igihe kirekire.

Nshobora gutwara imodoka nkanwa Baclofen?

Baclofen ishobora gutera gusinzira, isereri, no kugabanya ubushishozi, cyane cyane iyo utangiye kuyifata cyangwa iyo dose yawe yiyongereye. Izi ngaruka zirashobora kubuza ubushobozi bwawe bwo gutwara neza cyangwa gukoresha imashini.

Wirinda gutwara imodoka kugeza umenye uko baclofen ikugiraho ingaruka. Abantu bamwe bamenyera imiti mu minsi mike kandi bashobora gukomeza imirimo yabo isanzwe, mu gihe abandi bashobora gukomeza kumva baruhutse bikaba byatuma gutwara imodoka bidatekanye. Igihe cyose shyira imbere umutekano kandi uzirikane uburyo bwo gutwara abantu butandukanye niba wumva uruhutse cyangwa utameze neza.