Icyo Cevimeline ari cyo: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Cevimeline ni umuti wandikirwa na muganga ufasha umubiri wawe gukora amacandwe menshi n'amasozi. Yagenewe by'umwihariko abantu bafite indwara ya Sjögren, indwara y'ubwirinzi yibasira umubiri itera umunwa wumye cyane n'amaso yumye binyuze mu kwibasira imitsi ikora aya mazi y'ingenzi.

Uyu muti ukora nk'ugutera akanyabugabo mu ngingo zikora amacandwe, uzishishikariza gukora neza. Nubwo bitazavura indwara yihishe, cevimeline irashobora kuzamura cyane imibereho yawe n'ubuzima bwawe binyuze mu guhangana n'ibyo bimenyetso byo kumagara.

Cevimeline ni iki?

Cevimeline ni umwe mu itsinda ry'imiti yitwa cholinergic agonists. Tekereza nk'intumwa ya chimique yigana ibimenyetso sisitemu yawe y'imitsi yohereza mu buryo bwa kamere mu ngingo zikora amacandwe n'amasozi.

Uyu muti uza mu buryo bwa capsule kandi ufashwe mu kanwa. Yagurishwa ku izina rya Evoxac muri Leta Zunze Ubumwe z'Amerika. Muganga wawe azagusaba uyu muti mugihe izindi nshuti zo kuvura umunwa wumye zitatanze ubufasha buhagije.

Bitandukanye n'imiti imwe ikora mu mubiri wawe wose, cevimeline yagenewe kwibanda ku ngingo zihariye. Ubu buryo bwo kwibanda bufasha kugabanya ingaruka zitari ngombwa ku bindi bice by'umubiri wawe mugihe cyongera inyungu aho uzikeneye cyane.

Cevimeline ikoreshwa mu iki?

Cevimeline ikoreshwa cyane cyane mu kuvura ibimenyetso byo kumagara mu kanwa ku bantu bafite indwara ya Sjögren. Iyi ndwara y'ubwirinzi ituma sisitemu yawe y'ubwirinzi yibeshya igatera kwibasira imitsi ikora amacandwe n'amasozi.

Uyu muti ufasha gusubiza ubushuhe mu kanwa kawe, ibyo bishobora koroshya kurya, kuvuga, no kumeza. Abantu benshi bafite umunwa wumye cyane basanga ibikorwa byoroshye nko kuvuga igihe kirekire cyangwa kurya ibiryo bimwe na bimwe bigorana hatabayeho amacandwe ahagije.

Nubwo bitaremerwa ku mugaragaro ku zindi ndwara, abaganga bamwe bashobora kwandikira cevimeline ku kanwa gakama gaterwa na radiyo cyangwa imiti imwe n'imwe. Ariko, iyi mikoreshereze isaba ubugenzuzi bw'abaganga bwa nyuma kuko ibitera bitandukanye na syndrome ya Sjögren.

Cevimeline ikora ite?

Cevimeline ikora ituma imitsi ya muscarinic mu ngingo zawe zikora amavuta. Izi ngingo zimeze nk'ibishahuro, iyo byakoreshejwe, bibwira ingingo zawe gukora amavuta menshi yo mu kanwa n'amaso.

Uyu muti ufashwe nk'ufite imbaraga zikomeye mu gukora. Akenshi bitangira gukora mu minota 30 kugeza kuri 60 nyuma yo kuwufata, ibikorwa byinshi bikaba bibaho hafi isaha 1 kugeza ku masaha 2 nyuma yaho. Inyungu akenshi zimara amasaha menshi mbere yo kugenda buhoro buhoro.

Ingingo zawe zikora amavuta zisubiza cevimeline mu kongera umubare n'umuvuduko w'amavuta yo mu kanwa. Ibi byongera umusaruro bifasha gusubiza mu buzima busanzwe imikorere yo kurinda no gusiga amavuta yo mu kanwa, amenyo, n'umuhogo wawe.

Nkwiriye gufata cevimeline nte?

Fata cevimeline nk'uko umuganga wawe abitegeka, akenshi gatatu ku munsi ufite cyangwa udafite ibiryo. Urutonde rusanzwe akenshi ni 30 mg gatatu ku munsi, nubwo umuganga wawe ashobora kubihindura bitewe n'uko ubyitwaramo n'ingaruka zose zikubaho.

Ushobora gufata uyu muti hamwe n'amazi, amata, cyangwa umutobe. Nta biryo byihariye bisabwa, ariko kuwufata hamwe n'akantu gato k'ibiryo bishobora gufasha kugabanya isesemi niba wumva ubworoherwe ku miti. Gerageza gutandukanya imiti yawe mu gihe cy'umunsi, nk'ifunguro rya mu gitondo, ifunguro rya saa sita, n'ifunguro rya nimugoroba.

Kugira ubudahangarwa birakenewe kuri cevimeline. Kuwufata mu bihe bimwe na bimwe buri munsi bifasha gukomeza urwego ruri hejuru mu mubiri wawe kandi bitanga ubufasha bwizewe bw'ibimenyetso. Niba ukunda kwibagirwa imiti, tekereza gushyiraho ibyibutso kuri terefone cyangwa gukoresha umuteguro w'ibinyobwa.

Nkwiriye gufata cevimeline igihe kingana iki?

Cevimeline akenshi ni imiti ikoreshwa igihe kirekire uzakomeza kuyikoresha igihe cyose igufitiye akamaro kandi ukayihanganira neza. Kubera ko indwara ya Sjögren ari indwara ihoraho, imiti ikoreshwa buri gihe ikunze kuba ngombwa kugira ngo ugumane imbaraga zo kugabanya ibimenyetso.

Abantu benshi batangira kubona impinduka mu bimenyetso byo kumagara mu kanwa mu minsi mike cyangwa mu byumweru bya mbere byo kuvurwa. Ariko, bishobora gufata ibyumweru 6 kugira ngo umenye neza akamaro k'umuti. Muganga wawe azakurikirana uko witwara muri iki gihe cya mbere.

Inama zisanzwe zo gukurikirana ni ingenzi kugira ngo zigenzure uko umuti ukora neza no kureba niba hari ingaruka zose ziterwa nawo. Muganga wawe ashobora rimwe na rimwe gutanga ibitekerezo byo guhagarika imiti kugira ngo arebe niba ibimenyetso byawe byarushijeho gukira cyangwa niba ugikeneye gukomeza kuvurwa.

Ni izihe ngaruka ziterwa na Cevimeline?

Kimwe n'indi miti yose, cevimeline ishobora gutera ingaruka, nubwo abantu benshi bayihanganira neza. Ingaruka zisanzwe ziterwa n'ibikorwa byiyongera by'amashaza mu mubiri wawe.

Ingaruka ushobora guhura nazo muri rusange zigabanijwe mu byiciro bibiri: izisanzwe zibaho ku bantu benshi n'izidasanzwe zibaho ku bantu bake. Kubisobanukirwa birashobora kugufasha kumenya icyo witegura no kumenya igihe cyo kuvugana na muganga wawe.

Ingaruka zisanzwe zirimo:

• Kunyeganyega cyane, cyane cyane mu byumweru bya mbere byo kuvurwa
• Isesemi cyangwa kuribwa mu nda, akenshi bikagenda neza uko igihe kigenda
• Izuru riva amazi cyangwa imyanya yiyongera mu mazuru
• Impiswi cyangwa imyanda yoroshye
• Urugero, cyane cyane iyo uhagurutse vuba
• Umutwe
• Kunyara kenshi

Izi ngaruka zisanzwe akenshi zigabanuka uko umubiri wawe wimenyereza umuti. Abantu benshi basanga bigabanuka nyuma y'ibyumweru bya mbere byo kuvurwa.

Ingaruka zitari zisanzwe ariko zikomeye zirimo:

• Uburibwe bukomeye mu nda cyangwa kwikurura
• Kugorana guhumeka cyangwa guhumeka nabi
• Uburibwe mu gituza cyangwa umutima utera nabi
• Kuribwa umutwe cyane cyangwa kuvunika
• Imhinduka mu iyerekwa cyangwa uburibwe mu maso
• Ibyuya byinshi bibuza gukora imirimo ya buri munsi

Niba ubonye izi ngaruka zikomeye, vugana n'umuganga wawe ako kanya. Nubwo bitaba kenshi, ibi bimenyetso bishobora kwerekana ko umuti utagukwiriye cyangwa ko urugero rwawo rugomba guhindurwa.

Ninde utagomba gufata Cevimeline?

Cevimeline ntiboneye buri wese, kandi indwara zimwe na zimwe zituma bitakwemerwa cyangwa bigateza akaga gukoresha. Umuganga wawe azasuzuma neza amateka yawe y'ubuvuzi mbere yo kugutera uyu muti.

Abantu bafite indwara zihariye bagomba kwirinda cevimeline rwose kuko bishobora gukomeza ibimenyetso byabo cyangwa bikabangamira imiti yabo. Izi mpamvu zibujijwe zibaho kugirango zikurengere kandi zirinde imikoranire ishobora guteza akaga.

Ntabwo ugomba gufata cevimeline niba ufite:

• Asima itagenzurwa cyangwa ibibazo bikomeye byo guhumeka
• Glaucoma ifunganye (indwara ikomeye y'amaso)
• Indwara ikomeye y'umutima cyangwa imikorere y'umutima idasanzwe
• Ibibazo byo mu nda cyangwa ibisebe byo mu mara
• Indwara y'impyiko cyangwa umwijima bigira ingaruka zikomeye ku mikorere y'ingingo
• Amateka y'ibibazo byo gufatwa n'indwara y'igicuri
• Indwara ya Parkinson cyangwa izindi ndwara zo kwimuka

Byongeye kandi, abagore batwite cyangwa bonka bagomba kuganira ku byago n'inyungu n'umuganga wabo, kuko umutekano wa cevimeline mugihe cyo gutwita utarashyirwaho neza. Umuganga wawe azagereranya inyungu zishoboka n'ibibazo byose kuri wowe n'umwana wawe.

Amazina y'ubwoko bwa Cevimeline

Cevimeline iboneka munsi y'izina ry'ubwoko rya Evoxac muri Leta Zunze Ubumwe z'Amerika. Iyi ni verisiyo ikoreshwa cyane kandi yamenyekanye y'uyu muti.

Imiti ya cevimeline ikorwa n'abandi nayo iraboneka, ikoresha umuti umwe ariko ishobora gukorwa n'ibigo bitandukanye. Iyi miti ikorwa n'abandi akenshi ihendutse mugihe itanga akamaro kamwe ko kuvura.

Uko wakoresha Evoxac yitwa izina cyangwa cevimeline ikorwa n'abandi, umuti ukora kimwe. Umuganga wawe w'imiti ashobora kuganira ku itandukaniro ry'ibiciro kandi akagufasha gusobanukirwa uburyo bwiza bwo kwishyura ubwishingizi bwawe.

Uburyo bwo gusimbura Cevimeline

Niba cevimeline itagukundiye cyangwa ikagutera ingaruka mbi, hariho uburyo bwinshi bwo kuvura bwo gukoresha mu kugabanya ibimenyetso by'umunwa wumye. Muganga wawe ashobora kugufasha gushakisha izi nzira bitewe n'uko ubuzima bwawe bumeze.

Pilocarpine (Salagen) ni umuti usa na cevimeline. Ukora ukoresheje uburyo bumwe ariko abantu bamwe basubiza neza kuri umwe kurusha undi. Muganga wawe ashobora gutanga igitekerezo cyo guhindura niba utabona ubufasha buhagije muri cevimeline.

Uburyo bindi bwo kuvura burimo:

• Ibikoresho byo mu kanwa by'amavuta n'ibyo gukaraba mu kanwa
• Amavuta yo mu kanwa yandikirwa abantu bafite umunwa wumye
• Goma zitagira isukari n'ibintu byo konjesha mu kanwa bituma amavuta yo mu kanwa yiyongera
• Imiti ivura indwara ziterwa n'umubiri w'umuntu wanga ibyo wifitemo
• Impinduka mu mibereho nk'uko umuntu aguma mu mazi menshi no gukoresha icyuma gituma umwuka uba mwiza

Abantu benshi basanga guhuza cevimeline n'ubundi buryo butanga imiyoborere myiza y'ibimenyetso kurusha kwishingikiriza ku miti yonyine.

Ese Cevimeline iruta Pilocarpine?

Cevimeline na pilocarpine ni imiti ikora neza mu kuvura umunwa wumye, ariko bakora mu buryo butandukanye kandi bashobora gukwira abantu batandukanye neza. Nta muti n'umwe uruta undi.

Cevimeline ikunda gukora mu buryo bwihariye, bishobora gutuma abantu bamwe bagira ingaruka nke. Ifatwa kandi gatatu ku munsi, ibyo abarwayi bamwe babona ko byoroshye kurusha pilocarpine ifatwa kane ku munsi.

Pilocarpine imaze igihe kinini iboneka kandi ifite ubushakashatsi bwinshi buyishyigikira. Abantu bamwe bitwara neza kuri pilocarpine, mu gihe abandi bakunda cevimeline. Muganga wawe azatekereza ibimenyetso byawe byihariye, amateka yawe y'ubuvuzi, n'imibereho yawe ya buri munsi igihe agushyiriraho umuti wo kugerageza mbere.

Ibibazo Bikunze Kubazwa Kuri Cevimeline

Ese Cevimeline irakwiriye abantu barwaye diyabete?

Cevimeline muri rusange irashobora gukoreshwa neza ku bantu barwaye diyabete, ariko bisaba gukurikiranwa neza. Uyu muti ntugira ingaruka zigororotse ku isukari yo mu maraso, ariko ushobora kugira uruhare mu buryo umubiri wawe ukoresha amazi na electrolytes.

Muganga wawe azashaka gukurikirana isukari yo mu maraso yawe neza igihe utangiye gufata cevimeline, cyane cyane niba ufite ibibazo by'impyiko biturutse kuri diyabete. Kunyara cyane rimwe na rimwe bibaho hamwe na cevimeline bishobora kugira ingaruka ku miterere yawe y'amazi no kugenzura isukari yo mu maraso.

Nigira iki niba nanyoye cevimeline nyinshi bitunguranye?

Niba ufata cevimeline nyinshi kuruta uko byategetswe, vugana na muganga wawe cyangwa ikigo gishinzwe gukumira uburozi ako kanya. Kwiyongera k'umuti bishobora gutera ibyuya byinshi, isesemi, kuruka, impiswi, n'imihindukire y'umutima ishobora guteza akaga.

Ntugerageze kwivugisha niba utabitegetswe na muganga. Ahubwo, nywa amazi kugira ngo ugume mu mazi menshi kandi usabe ubufasha bw'ubuvuzi vuba. Zana icupa ry'umuti kugira ngo wereke abaganga neza icyo wanyoye n'ingano yacyo.

Nigira iki niba nciwe doze ya cevimeline?

Niba wibagiwe gufata urugero rwa cevimeline, rufate uko wibukije, keretse igihe cyegereye igihe cyo gufata urugero rukurikira. Muri urwo rubanza, reka urugero wibagiwe ukomeze gahunda yawe isanzwe.

Ntuzigere ufata urugero ebyiri icyarimwe kugira ngo usubize urugero wibagiwe, kuko ibyo byongera ibyago byo kugira ingaruka zidakunda. Niba ukunda kwibagirwa urugero, tekereza gushyiraho ibyibutsa kuri terefone yawe cyangwa ukoreshe umuteguro w'imiti wo mu cyumweru kugira ngo bigufashe kuguma ku murongo.

Nshobora Kureka Gufata Cevimeline Ryari?

Ugomba kureka gufata cevimeline gusa ukurikije ubuyobozi bwa muganga wawe. Kubera ko ivura indwara ihoraho, kureka umuti mubisanzwe bizatuma ibimenyetso byo kumva umunwa wumye bisubira muri icyo gihe mu minsi mike cyangwa mu byumweru.

Muganga wawe ashobora gutanga igitekerezo cyo kureka cevimeline niba ugize ingaruka zidakunda, niba indwara yawe yoroshye cyane, cyangwa niba ushaka kugerageza uburyo bwo kuvura butandukanye. Bazagufasha gukora gahunda yo gucunga ibimenyetso byawe mugihe cyose cyo guhindura imiti.

Nshobora Kunywa Alcool Ngihe Ndafata Cevimeline?

Nibyiza kugabanya kunywa alcool mugihe ufata cevimeline, kuko alcool ishobora gutuma ibimenyetso byo kumva umunwa wumye birushaho kandi bishobora kongera ingaruka zimwe na zimwe nk'izindi zikomerekeje. Alcool kandi ikora nka diuretic, ishobora kongera kunyara byinshi rimwe na rimwe bibaho hamwe na cevimeline.

Niba uhisemo kunywa alcool rimwe na rimwe, bikore mu rugero kandi ugume wihaze amazi. Ganira na muganga wawe kubyerekeye urwego rwo kunywa alcool, niba hariho, bikwiye kubera imiterere yawe yihariye n'ubuzima bwawe.