Icyo Urukingo rwa Chymopapain Ariryo: Ibikoreshwa, Uburyo Bwo Gukoresha, Ingaruka Ziterwa n'Ibindi

Urukingo rwa Chymopapain ni umuti wihariye ukoreshwa mu gusenyera ibice by'imitsi y'umugongo yari yarangiritse. Uyu muti wubakiye kuri poroteyine ukora mu gusenya ikintu gisa na jeli kiri mu mpande z'umugongo gishobora gukanda imitsi igatuma ubabara. Nubwo uyu muti wari ufitiye icyizere abantu barwaye umugongo cyane, ntukiboneka cyane kubera impungenge z'umutekano zagiye zigaragara uko imyaka yagiye yicuma.

Chymopapain ni iki?

Chymopapain ni enzyme ikomoka ku giti cya papaya ifite ubushobozi bwo gusenya poroteyine zimwe na zimwe. Iyo yatewe mu mpande z'umugongo zangiritse, isenya nucleus pulposus - igice cyoroshye, gisa na jeli kiri hagati y'urwo ruhande rushobora kuzamo imbaraga no gukanda imitsi yegereyeho. Ubu buryo bwitwa chemonucleolysis, bisobanura mu buryo butaziguye “gusenya imiti ya nucleus.”

Uyu muti ubarirwa mu cyiciro cy'imiti yitwa proteolytic enzymes, ari zo poroteyine zishobora gusenya izindi poroteyine. Tekereza nk'icyuma gishobora guca mu bice by'umubiri byihariye. Iki gikorwa cyihariye cyagize ko kiba igisubizo cyiza ku kubagwa umugongo gakondo ku barwayi bamwe na bamwe.

Chymopapain ikoreshwa mu iki?

Urukingo rwa Chymopapain rwakoreshwaga cyane mu kuvura impande z'umugongo zangiritse - ibyo byiyongera bibabaza mu mugongo wo hasi bishobora gutera ububabare bukomeye, urugimbu, no kunanuka. Ubu buvuzi bwatekerezwaga iyo uburyo bwo kwirinda nk'ikiruhuko, imyitozo ngororamubiri, n'imiti bitari byatanze ubufasha buhagije.

Ubu buryo bwari bwashyizweho by'umwihariko ku barwayi bafite impande z'umugongo zagaragaye ko zangiritse bafite ububabare burambye mu kuguru (sciatica) bwaturukaga mu mugongo wo hasi. Muganga wawe yagutera uyu muti gusa nyuma yo gukoresha ubundi buryo butagomba kubagwa, ariko mbere yo gutekereza kubagwa umugongo.

Ariko, ni ngombwa kumenya ko inshinge ya chymopapain itagikoreshwa cyane mu bihugu byinshi, harimo n'Amerika, kubera ibimenyetso by'uburwayi bukomeye bw'uburwayi ndetse n'iterambere ry'imiti ifite umutekano kandi ikora neza.

Chymopapain ikora ite?

Chymopapain ikora yibanda ku ntungamubiri zidasanzwe zigize ibikoresho bya disiki yagize ikibazo. Iyo yatewe inshinge mu disiki yagize ikibazo, uruganda rutangira gusenya nucleus pulposus - hagati yoroshye yateye hanze y'igice cy'inyuma cya disiki.

Ubu buryo bwo gusenya bugabanya ubunini bwa herniation, bushobora kugabanya umuvuduko ku mitsi yo mu mugongo yegeranye. Iyo ibikoresho bya disiki bishize, umuvuduko watezaga ububabare bwawe, ubushyuhe, cyangwa intege nke birashobora kugabanuka cyane. Ubu buryo bwose busanzwe bufata ibyumweru byinshi kugeza ku mezi menshi kugira ngo bugire ingaruka zose.

Bikwiye kwitonderwa ko ibi byafatwaga nk'uburyo bwo kuvura buri hagati - bukomeye kurusha imiti cyangwa imyitozo ngororamubiri, ariko ntibinjira cyane kurusha kubagwa mu mugongo. Igikorwa cy'uruganda ntigishobora guhindurwa iyo cyatewe inshinge, niyo mpamvu guhitamo abarwayi bitonze byari ngombwa.

Chymopapain igomba gutangwa ite?

Inshinge ya Chymopapain yajyaga ikorwa nk'uburyo bwo kuvura mu bitaro cyangwa mu kigo cyihariye. Ntabwo wajyaga ufata iyi miti mu rugo cyangwa mu bundi buryo ubwo aribwo bwose uretse gutera inshinge mu disiki yo mu mugongo.

Mbere yo gukora ubu buryo, ubusanzwe wagombaga kwiyiriza amasaha menshi, kimwe no kwitegura kubagwa. Inshinge ubwayo yakorwaga hakoreshejwe anesthesia yaho kandi ikoreshwa na X-ray kugira ngo habeho gushyirwa neza. Ubu buryo bwose busanzwe bufata iminota 30 kugeza kuri 60.

Nyuma yo guterwa urushinge, byari ngombwa ko uguma mu bitaro kugira ngo ukurikiranwe, akenshi amasaha 24 kugeza kuri 48. Iki gihe cyo gukurikiranwa cyari ingenzi kuko ibimenyetso bikomeye byo kwibasirwa n'umubiri byashoboraga kugaragara nyuma y'amasaha menshi nyuma y'uburyo bwakoreshejwe. Itsinda ryawe ry'abaganga ryagombaga kureba ibimenyetso byose by'ingorane muri iki gihe cy'ingenzi.

Ubuvuzi bwa Chymopapain bugomba kumara igihe kingana iki?

Urushinge rwa Chymopapain akenshi rwakorwaga rimwe gusa aho kuba ubuvuzi buhoraho. Iyo ruterwa, urwo rugingo rwakoraga mu byumweru n'amezi yakurikiraga kugira ngo rushonye ibikoresho bya disiki. Abantu benshi barabonaga impinduka buhoro buhoro nyuma y'ibyumweru 2 kugeza kuri 12 nyuma yo guterwa urushinge.

Ingaruka muri rusange zafatwaga nk'izihoraho kuko urwo rugingo rwangizaga ibikoresho bya disiki ku buryo butagaruka. Ariko, ibyo ntibyabuzaga ibibazo bishya bya disiki kwaduka mu tundi duce tw'umugongo wawe uko igihe kigenda. Abantu bamwe basabwaga gusubiramo ubuvuzi, ariko ibyo byari bike.

Igihe cyo gukira kwawe cyaterwaga n'ibintu bitandukanye, harimo ubunini bw'ikibazo cyawe cy'umwimerere, ubuzima bwawe muri rusange, n'uburyo wakurikizaga amabwiriza yo kwitabwaho nyuma y'ubuvuzi. Imyitozo ngororamubiri yakundaga gukoreshwa kugira ngo ifashe gukomeza imitsi yo mu mugongo wawe mu gihe cyo gukira.

Ni izihe ngaruka ziterwa na Chymopapain?

Kumva ingaruka zishobora guterwa no guterwa urushinge rwa chymopapain bifasha gusobanura impamvu ubuvuzi butagikoreshwa cyane. Nubwo abarwayi benshi bagize igisubizo cyiza cyo kugabanya ububabare, ibyago byarushijeho inyungu ku baganga benshi.

Ingaruka zisanzwe zari zikorerwa kandi zirimo kubabara mu mugongo ahaterwa urushinge, imitsi yikanyaga, no gukomera by'igihe gito. Ibi bimenyetso akenshi byamaraga iminsi mike kugeza ku byumweru kandi byashoboraga kuvurwa n'imiti igabanya ububabare no kwimuka gahoro.

Dore ingaruka zikunze kugaragara ushobora kuba waragize:

• Kubabara umugongo bikomeye mu minsi mike nyuma yo guterwa urushinge
• Imitsi y'umugongo yo hasi yikanyaga
• Umubiri uguma ukomeye kandi ntugenda neza by'igihe gito
• Urubura ruto cyangwa kumva umubiri utameze neza
• Kubabara ahantu baterwa urushinge

Ibi bimenyetso bisanzwe byari mu buryo umubiri wawe wakiragamo imiti, igihe umubiri wawe wakiraga enzyme n'ibikoresho byo mu gice cy'uruti rw'umugongo byasenyukaga.

Ariko, ingaruka zikomeye ni zo zatumye chymopapain itongera gukoreshwa. Ikibazo gikomeye cyari ukubabara bikomeye bitewe n'uburwayi, bishobora gutera urupfu kandi byabayeho ku bantu bagera kuri 1%.

Dore ingaruka zikomeye zasabaga ubufasha bwihuse bw'abaganga:

• Kubabara bikomeye bitewe n'uburwayi (anaphylaxis) bigaragarira mu guhumeka bigoranye, kubyimba, no kugabanuka gukomeye kw'amaraso
• Ukwangirika kw'imitsi bitera intege nke cyangwa urugingo rutarumva
• Udukoko ahantu baterwa urushinge cyangwa mu ruti rw'umugongo
• Ibibazo byo kuva amaraso
• Kubabara umugongo bikomeye, bidakira

Ibi bibazo bikomeye, nubwo bitabaho kenshi, byari bikomeye ku buryo ibigo byinshi by'ubuvuzi byahagaritse gutanga urushinge rwa chymopapain, maze bikoresha izindi miti zifite umutekano kurusha yo.

Ninde utagomba gufata Chymopapain?

Amatsinda menshi y'abantu yafatwaga nk'abatabereye gukoresha urushinge rwa chymopapain bitewe n'ibibazo byiyongera. Muganga wawe yagombaga gusuzuma neza amateka yawe y'ubuzima n'uburwayi bwawe mbere yo gutekereza kuri ubu buvuzi.

Ntuzaba umuntu ukwiriye gukoresha urushinge rwa chymopapain niba ufite allergie izwi kuri papaya, imiti ituma inyama zorohera, cyangwa wigeze ukoresha chymopapain mbere. Abantu bafite uburwayi bw'uruti rw'umugongo, nka infection z'uruti rw'umugongo, ibibyimba, cyangwa indwara ya arthritis ikomeye, na bo ntibemerewe guhabwa ubu buvuzi.

Dore ibibazo by'ingenzi byagutuma utabona urushinge rwa chymopapain:

• Uburwayi bwo kwibasirwa na allergie ku papaya cyangwa ibicuruzwa birimo papain
• Gusama cyangwa konsa
• Uburwayi bukomeye bwo mu mugongo
• Ibimeme byo mu mugongo cyangwa kanseri
• Uburwayi bukomeye bwo kuva amaraso
• Uburwayi bumwe na bumwe bwo kwibasirwa n'umubiri
• Kubagwa mu mugongo mbere ho ku rwego rumwe

Byongeye kandi, abana n'abantu bakuze bafite uburwayi bwinshi muri rusange ntibafatwaga nk'abantu bakwiriye kubagwa kubera ibyago byinshi byo kugira ibibazo.

Amazina y'ubwoko bwa Chymopapain

Umuti wa chymopapain watezaga imbere izina ry'ubwoko rya Chymodiactin igihe yari iboneka. Iri ni ryo ryari ifumbire y'ibanze yakoreshwaga mu buvuzi mu myaka ya za 1980 n'intangiriro za za 1990.

Chymodiactin yakorwaga na Travenol Laboratories hanyuma na sosiyete zindi zikora imiti. Uyu muti wazaga mu ifu yagombaga kuvangwa n'umuti wihariye mbere yo guterwa urushinge. Uku gutegurwa byasabaga kwitonda no kubika neza kugira ngo umuti ukore neza.

Uyu munsi, ntuzabona urushinge rwa chymopapain ruboneka mu izina ry'ubwoko ubwo aribwo bwose mu bihugu byinshi, kuko rwavanyweho ku isoko kubera impungenge z'umutekano n'uko hari ubundi buryo bwo kuvura bwiza.

Uburyo bwo gusimbura Chymopapain

Ubuvuzi bwa none butanga uburyo butandukanye bwo gusimbura urushinge rwa chymopapain rutekanye kandi rukora neza mu kuvura disiki zangiritse. Ubu buryo bwasimbuye cyane chymopapain kuko butanga umutekano mwinshi kandi akenshi butanga ibisubizo byiza.

Uburyo busanzwe bwo gusimbura burimo uburyo bwo kubaga butavuna cyane nk'uburyo bwa microdiscectomy, bukura ibikoresho bya disiki yangiritse binyuze mu gace gato. Ubu buryo bufite intsinzi nziza kandi bufite ibyago bike byo kugira ibibazo bikomeye ugereranije n'urushinge rwa chymopapain.

Dore uburyo nyamukuru bwo gusimbura umuganga wawe ashobora kugusaba uyu munsi:

• Kubaga hifashishijwe uburyo butuma umuntu adakomereka cyane (Microdiscectomy) - kubaga hagamijwe gukuraho ibikoresho byo mu ngingo zihujwe
• Inshinge za steroidi zitera kuturuka mu ngingo (Epidural steroid injections) - imiti igabanya ububabare iterwa mu nzira z'imitsi zikomeretse
• Imyitozo ngororamubiri na gahunda zayo
• Gukoresha imirasire ya radio kugabanya ububabare buterwa n'imitsi (Radiofrequency ablation) - gukoresha ubushyuhe kugabanya ibimenyetso by'ububabare buturuka mu mitsi
• Ubuvuzi bugabanya umuvuduko mu mugongo
• Uburyo bugezweho bwo kuvura ububabare

Ubu buvuzi bwa none muri rusange butanga umusaruro mwiza kandi bufite ibyago bike, ni yo mpamvu bwahindutse uburyo bwo kuvura ibibazo byo mu ngingo zihujwe.

Ese Chymopapain iruta izindi nshuti zo mu ngingo zihujwe?

Ugereranije chymopapain n'ubuvuzi bugezweho bw'ibibazo byo mu ngingo zihujwe, uburyo bushya muri rusange bufatwa nk'uburuta mu bijyanye n'umutekano n'ubushobozi. Nubwo chymopapain yafashije abarwayi bamwe kwirinda kubagwa bikomeye, ibyago byagaragaye ko ari byinshi cyane ku buryo bitakoreshwa cyane.

Uburyo bwo kubaga bugezweho butuma umuntu adakomereka cyane nka microdiscectomy bufite urugero rwo gukira rwa 85-95% ku bantu babikwiriye, ugereranije n'urugero rwo gukira rwa chymopapain rwa 70%. Ikindi cy'ingenzi, urugero rwo guhura n'ibibazo bikomeye ruri hasi cyane mu buvuzi bwa none.

Uburyo bwa none kandi butanga umusaruro witezwe kandi igihe cyo gukira kigahuta. Abarwayi benshi bakorerwa microdiscectomy bashobora gusubira mu bikorwa bisanzwe mu byumweru 2-6, mu gihe inshinge za chymopapain akenshi byasabaga amezi 2-3 kugira ngo bigire ingaruka zose. Ubushobozi bwo gukemura ikibazo mu buryo butaziguye binyuze mu kubaga kandi bisobanura ko hariho gushidikanya guke ku bijyanye niba ubuvuzi buzagira akamaro.

Ibibazo bikunze kubazwa kuri Chymopapain

Q1. Ese chymopapain irakwiriye ku bantu barwaye diyabete?

Igihe chymopapain yari iboneka, abantu barwaye diyabete bashoboraga kwakirwa ubu buvuzi, ariko byasabaga gukurikiranwa no kwitabwaho by'umwihariko. Diyabete ishobora kugira ingaruka ku gukira no kongera ibyago byo kwandura indwara, bityo muganga wawe yagombaga gusuzuma neza uko isukari yo mu maraso yawe yifashe n'ubuzima bwawe muri rusange. Ariko, kubera ko chymopapain itagihari cyane, ibi ni ibitekerezo by'amateka.

Q2. Nakora iki niba mbonye chymopapain nyinshi ku buryo butunganye?

Kurenza urugero rwa chymopapain byari bike cyane kuko uyu muti watangwaga gusa n'abantu b'inzobere mu by'ubuvuzi mu bitaro byagenzurwaga. Niba byabaho ko umuti urenze urugero, byahita bikurikiranwa n'ikipe y'abaganga bafashwa, gukurikiranwa neza, no kuvura ibimenyetso byose by'uburwayi. Ibi ni kimwe mu byatumye iki gikorwa gisaba ko umuntu arara mu bitaro kugira ngo arebe uko bimeze.

Q3. Nakora iki niba nsubije inkingo ya chymopapain?

Iki kibazo ntikireba inkingo ya chymopapain kuko yari igikorwa kimwe cyakorerwaga mu kigo cy'ubuvuzi, atari umuti wafataga mu rugo ku gihe runaka. Igihe wari umaze guhabwa urukingo, urwo ruganda rwakoraga buri gihe kugira ngo rusenye ibikoresho byo mu gice cy'umugongo mu byumweru n'amezi akurikira.

Q4. Nshobora kureka gufata chymopapain ryari?

Ntabwo "ureka gufata" chymopapain mu buryo busanzwe kuko yari urukingo rumwe. Igihe wari umaze guterwa urukingo, urwo ruganda rwakoraga mu byumweru byinshi kugeza ku mezi menshi kugeza rurangije gusenyera ibikoresho byo mu gice cy'umugongo. Ingaruka zayo muri rusange zari izahoraho, nubwo ushobora gukenera izindi mvura niba wateza ibibazo bishya byo mu gice cy'umugongo mu tundi duce twawo.

Q5. Hariho ingaruka zirambye ziterwa n'inkingo ya chymopapain?

Abantu benshi bakiriye urukingo rwa chymopapain batagize ibibazo bagize umuti urambye ku mubabaro wabo watewe n'imitsi. Ariko, abantu bamwe bagize ibibazo birambye, harimo kubabara umugongo bya hato na hato, kugabanuka kw'imikorere y'umugongo, cyangwa kwishyira mu bintu. Imiterere ihoraho yo gusenyuka kw'ibikoresho by'imitsi byasobanuraga ko ingaruka, zaba nziza cyangwa mbi, zari zihamye. Iki ni ikindi kintu gituma ubuvuzi bwa none, bushobora guhinduka, bukunda gukoreshwa uyu munsi.