Icyo Clomipramine ari cyo: Ibyo ikoreshwa, urugero rwa dose, ingaruka zayo n'ibindi

Clomipramine ni umuti wandikirwa na muganga ugwa mu itsinda ry'imiti ivura umubabaro yitwa tricyclic antidepressants (TCAs). Muganga wawe ashobora kukwandikira uyu muti kugira ngo ufashwe kuvura indwara yo guhuzagurika (OCD) cyangwa ubwoko bumwe na bumwe bwo kwiheba igihe izindi nshuti zitagize icyo zikora.

Uyu muti umaze imyaka myinshi ufasha abantu gucunga ubuzima bwabo bwo mu mutwe. Nubwo ari ubwoko bwa kera bwo kuvura umubabaro, bushobora kugira akamaro kanini ku ndwara zimwe na zimwe, cyane cyane OCD, aho akenshi ikora neza kurusha imiti mishya.

Clomipramine ni iki?

Clomipramine ni tricyclic antidepressant ikora mugihe yuzuzanya imisemburo imwe yo mu bwonko yitwa neurotransmitters. Ni umuti umwe niyo waba uwuzi ku izina ryayo risanzwe rya clomipramine cyangwa izina ryayo ry'ubucuruzi rya Anafranil.

Uyu muti ni uwihariye cyane kuko ni umwe mu miti ikora neza cyane iboneka yo kuvura indwara yo guhuzagurika. Bitandukanye n'indi miti myinshi ivura umubabaro, clomipramine ifite uburyo bwihariye bwo kugira ingaruka ku mikorere y'ubwonko bituma ifasha cyane abantu bafite OCD.

Muganga wawe akenshi azagutangiza ku rugero ruto hanyuma akagenda arwongera buhoro buhoro mu byumweru byinshi. Ubu buryo butinda bufasha umubiri wawe kumenyera umuti kandi bugabanya amahirwe yo kugira ingaruka ziterwa n'umuti.

Clomipramine ikoreshwa mu kuvura iki?

Clomipramine ikoreshwa cyane cyane mu kuvura indwara yo guhuzagurika (OCD), aho ishobora kugabanya cyane ibitekerezo byo guhuzagurika n'imyitwarire yo guhatirwa. Ikoreshwa kandi mu kuvura ubwoko bumwe na bumwe bwo kwiheba, cyane cyane iyo indi miti ivura umubabaro itagize icyo ikora.

Kubera OCD, uyu muti ushobora gufasha gucecekesha ibitekerezo bihoraho, bitifuzwa bigaragara ko bidashoboka kubicunga. Irashobora kandi kugabanya icyifuzo cyo gukora imyitwarire isubiramo nk'ukoza intoki cyane, kugenzura, cyangwa kubara.

Rimwe na rimwe, abaganga bandika imiti ya clomipramine ku bindi bibazo bifitanye isano n'imikorere y'ubwonko. Ibyo bishobora kuba birimo indwara zimwe na zimwe z'ubwoba, indwara yo guhagarika umutima, cyangwa ndetse n'indwara z'ububabare bwa hato na hato aho imiti ifite ingaruka ku bimenyetso by'imitsi bishobora gufasha.

Clomipramine ikora ite?

Clomipramine ikora yongera urwego rwa serotonin mu bwonko bwawe, ubutumwa bwa kemikali bufasha kugenzura imitekerereze, ubwoba, n'ibitekerezo byo guhuzagurika. Ikomanga kongera kwinjizwa kwa serotonin, ikemerera byinshi muri byo gukomeza gukora hagati y'uturemangingo tw'ubwonko.

Uyu muti ufatwa nk'uvura neza kandi neza, cyane cyane kuri OCD. Ni ukuri ni umwe mu miti ikomeye kandi ifite akamaro kubijyanye n'ibimenyetso byo guhuzagurika, akenshi ikora iyo izindi miti itatanze ubufasha buhagije.

Uyu muti kandi ugira ingaruka ku bindi binyabutabazi by'ubwonko nka norepinephrine, niyo mpamvu bishobora gufasha mu gukemura umubabaro no mu bwoko bumwe na bumwe bw'ububabare bwa hato na hato. Ariko, iyi ngaruka yagutse ku mikorere y'ubwonko bisobanura ko ishobora gutera ingaruka nyinshi kurusha imiti mishya.

Nkwiriye gufata clomipramine nte?

Fata clomipramine nk'uko umuganga wawe abitegeka, akenshi rimwe cyangwa kabiri ku munsi hamwe n'ibiryo kugirango ugabanye ibibazo byo mu nda. Urashobora kuyifata n'amata cyangwa ikirahure kinini cy'amazi, kandi kurya ibiryo mu gifu bifasha kwirinda isesemi.

Nibyiza gufata urugero rwawe ku gihe kimwe buri munsi kugirango ugumane urwego ruzigama mu mubiri wawe. Abantu benshi basanga kuyifata nimugoroba bikora neza kuko bishobora gutera gusinzira, bishobora gufasha gusinzira.

Ntukamenagure, ntukayisye, cyangwa ntukayice uretse niba umuganga wawe akubwiye byumwihariko. Ibimire byose hamwe n'amazi menshi. Niba ufata ifishi ya capsule, urashobora kuyifungura hanyuma ugatobora ibiyirimo kuri applesauce niba kumira bigoye.

Irinde kunywa inzoga igihe urimo gufata clomipramine, kuko bishobora kongera ibitotsi n'izindi ngaruka. Nanone, gerageza kwitonda ku mutobe wa pome, kuko ushobora kugira ingaruka ku buryo umubiri wawe ukoresha imiti.

Nzamara Igihe Kingana Gite Ndafatwa Clomipramine?

Abantu benshi bakeneye gufata clomipramine amezi menshi kugeza ku myaka myinshi kugira ngo bagumane ibyiza byayo, cyane cyane mu kuvura OCD. Muganga wawe azakorana nawe kugira ngo abone igihe gikwiye gishingiye ku buryo urimo witwara neza n'uko ibimenyetso byawe birimo bikira.

Ubusanzwe uzatangira kubona impinduka zimwe na zimwe mu bimenyetso byawe nyuma y'ibyumweru 2-4, ariko bishobora gufata ibyumweru 8-12 kugira ngo ubone ibyiza byose. Ntukacike intege niba utabonye impinduka ako kanya – iyi miti ifata igihe kugira ngo yubake mu mubiri wawe.

Kubera OCD, abantu benshi bakeneye kuvurwa igihe kirekire kugira ngo birinde ko ibimenyetso bisubira. Muganga wawe ashobora kugusaba gukomeza gufata imiti nibura umwaka umwe nyuma y'uko ibimenyetso byawe bikize, hanyuma ugabanye buhoro buhoro urugero rw'umuti niba bikwiye.

Ntuzigere uhagarika gufata clomipramine ako kanya, n'iyo wumva umeze neza. Guhagarika vuba cyane bishobora gutera ibimenyetso byo kuva mu miti nk'izunguzungu, isesemi, n'ibimenyetso bisa n'ibicurane. Muganga wawe azagufasha kugabanya buhoro buhoro igihe kigeze.

Ni Iyihe Ngaruka Ziterwa na Clomipramine?

Kimwe n'indi miti yose, clomipramine ishobora gutera ingaruka, nubwo atari buri wese uzibona. Ingaruka zisanzwe zikunze kuba zoroshye kandi akenshi zikagenda uko umubiri wawe wimenyereza imiti mu byumweru bike bya mbere.

Dore ingaruka ushobora guhura nazo, dutangiriye ku zisanzwe abantu benshi babona:

• Umutuzo no kunanirwa (bikunda kubaho cyane, cyane cyane igihe ugitangira)
• Umunwa wumye (kunywa amazi no gushyiraho chingamu idafite isukari birashobora gufasha)
• Kubura umwanya (kongera imigozi n'amazi birafasha)
• Urugero, cyane cyane iyo uhagurutse vuba
• Kureba nabi (muri rusange by'igihe gito)
• Kongera ibiro (muri rusange bigenda buhoro buhoro)
• Kugorana kwihagarika cyangwa gutinda kwihagarika
• Kunyagira cyane
• Umubiri utenda cyangwa guhinda umushyitsi mu ntoki
• Isesemi, cyane cyane niba ifashwe itarimo ibiryo

Ibyo bice byinshi by'ingaruka zishobora gucungwa kandi bikagenda bigabanuka uko igihe kigenda. Gufata umuti hamwe n'ibiryo, kuguma mu mazi, no guhaguruka buhoro buhoro uvuye mu kwicara cyangwa kuryama bishobora gufasha kugabanya izo ngaruka nyinshi.

Abantu bamwe bashobora guhura n'ingaruka zitamenyerewe ariko ziteye impungenge zikeneye ubufasha bw'abaganga:

• Umutima utera cyane cyangwa mu buryo butari busanzwe
• Urugero rukabije cyangwa guta ubwenge
• Kuvurungana cyangwa ibibazo byo kwibuka
• Kubura umwanya gukabije kumara iminsi irenga mike
• Kugorana guhumeka cyangwa guhagarara mu gituza
• Gusohoka amaraso bidasanzwe cyangwa gukomeretsa
• Umutwe ukabije
• Impinduka mu mikorere y'imibonano mpuzabitsina

Ingaruka zitamenyerewe ariko zikomeye zirimo gufatwa n'ibibazo (bikenewe cyane ku doze ndende), ibikorwa bikabije byo kwanga umuti, n'ibibazo by'umutima. Niba uhuye n'ibimenyetso bikabije, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bwihutirwa.

Ninde utagomba gufata Clomipramine?

Clomipramine ntirinzwe kuri buri wese, kandi umuganga wawe azasuzuma neza amateka yawe mbere yo kuyandika. Ntugomba gufata uyu muti niba umaze kugira umutima utera cyane cyangwa niba uri gufata indi miti imwe.

Abantu bafite ibibazo by'umutima bakeneye kwitonda by'umwihariko, kuko clomipramine ishobora kugira ingaruka ku mutima. Umuganga wawe ashobora gutumiza electrocardiogram (EKG) mbere yo gutangira kuvurwa niba ufite impungenge z'umutima.

Ugomba kwirinda clomipramine niba ufite:

• Umutima umaze iminsi mike utera uburwayi (mu mezi make ashize)
• Uburwayi bukomeye bwo mu mutima butuma umutima utera nabi
• Glaucoma idakira y'amaso
• Uburwayi bukomeye bwo mu mwijima
• Allergie izwi kuri clomipramine cyangwa imiti isa nayo
• Gukoresha ubu imiti yitwa MAO inhibitors (ugomba gutegereza iminsi 14 umaze kuyihagarika)

Ukwitonda by'umwihariko birakenewe niba urwaye diyabete, ibibazo bya tiroyide, prostate yagutse, cyangwa ufite amateka y'ibibazo byo gufatwa n'ibihungabanyo. Muganga wawe azakugenzura neza niba ufite kimwe muri ibyo bibazo.

Abagore batwite cyangwa bonka bagomba kuganira ku byago n'inyungu neza na muganga wabo, kuko umuti ushobora kujya ku mwana.

Amazina y'ubwoko bwa Clomipramine

Clomipramine iboneka ku izina ry'ubwoko bwa Anafranil, rikaba ari ryo rikoreshwa cyane muri Leta Zunze Ubumwe z'Amerika. Clomipramine ya generic na Anafranil y'izina ry'ubwoko birimo ibintu bikora kimwe kandi bikora kimwe.

Farumasi yawe ishobora kuguha verisiyo ya generic cyangwa izina ry'ubwoko bitewe n'ubwishingizi bwawe n'icyo gihari. Uburyo bwombi bufite akamaro kamwe, nubwo abantu bamwe bakunda gukoresha uburyo bumwe kugira ngo babigumane.

Umuti uza mu mbaraga zitandukanye, akenshi 25mg, 50mg, na 75mg capsules cyangwa ibinini. Muganga wawe azakwandikira imbaraga zikwiriye ibyo ukeneye.

Uburyo bwo gusimbuza Clomipramine

Niba clomipramine itagukundiye cyangwa ikagutera ingaruka nyinshi, indi miti myinshi ishobora kuvura ibibazo bisa. Kubera OCD, selective serotonin reuptake inhibitors (SSRIs) nka fluoxetine, sertraline, cyangwa fluvoxamine ni ibisubizo bisanzwe.

Iyi miti mishya yo kurwanya depression akenshi ifite ingaruka nke kurusha clomipramine, nubwo ashobora kutagira akamaro ku bimenyetso bikomeye bya OCD. Muganga wawe ashobora kubanza kugerageza SSRI, cyane cyane niba ukiri muto cyangwa ufite impungenge ku ngaruka.

Ku birebana no kwiheba, hariho izindi nzira nyinshi zirimo izindi miti ivura kwiheba ya tricyclic, SSRIs, SNRIs, n'imiti mishya ifite uburyo butandukanye bwo gukora. Guhitamo biterwa n'ibimenyetso byawe byihariye n'amateka yawe y'ubuvuzi.

Ese Clomipramine iruta Fluoxetine?

Clomipramine na fluoxetine (Prozac) byombi ni imiti ivura kwiheba ifite akamaro, ariko bikora mu buryo butandukanye kandi bifite imbaraga zitandukanye. By'umwihariko kuri OCD, clomipramine akenshi ifatwa nk'ifite akamaro kurusha izindi, mugihe fluoxetine akenshi igira ingaruka nke.

Clomipramine muri rusange irakomeye ku bimenyetso bya OCD kandi ishobora gukora iyo indi miti itagize icyo igeraho. Ariko, fluoxetine akenshi yihanganirwa neza, cyane cyane nabantu bakuze cyangwa abantu bafite ubwumvikane ku ngaruka ziterwa n'imiti.

Muganga wawe azatekereza ku bimenyetso byawe byihariye, amateka yawe y'ubuvuzi, no kwihanganira ingaruka ziterwa n'imiti mugihe uhitamo hagati yiyi miti. Abantu bamwe babaho neza hamwe n'imwe kurusha iyindi, kandi ntibishoboka buri gihe kumenya niba ari iyihe izagukorera neza.

Ibikunze Kubazwa Kuri Clomipramine

Ese Clomipramine irakwiriye indwara z'umutima?

Clomipramine isaba gukurikiranwa neza kubantu bafite indwara z'umutima kuko ishobora kugira ingaruka kumuvuduko w'umutima n'umuvuduko w'amaraso. Muganga wawe ashobora gutegura ibizamini by'umutima mbere yo gutangira kuvura niba ufite indwara iyo ariyo yose y'umutima.

Abantu bafite indwara z'umutima zidakuka akenshi bashobora gufata clomipramine neza hamwe no gukurikiranwa neza, ariko abafite ibitero by'umutima bya vuba cyangwa ibibazo bikomeye by'umuvuduko w'umutima bagomba kuyirinda. Umuganga wawe w'umutima na psychiatre bazakorana kugirango bamenye niba bikwiriye kuri wewe.

Nigira iki niba mfashe clomipramine nyinshi nk'uko byateganijwe?

Niba ufata clomipramine nyinshi nk'uko byateganijwe, vugana na muganga wawe ako kanya cyangwa uhamagare umuntu uvura uburozi kuri 1-800-222-1222. Gufata nyinshi bishobora gutera ibibazo by'umuvuduko w'umutima, ibibazo byo gufatwa, cyangwa gusinzira cyane.

Ntugategereze kureba niba ibimenyetso bigaragara – genda gushaka ubufasha bw'ubuvuzi ako kanya. Zana icupa ry'umuti kugira ngo werekane neza icyo wafashe n'ingano yacyo. Ubuvuzi bwihutirwa bugira akamaro cyane iyo butangiye vuba.

Nkwiriye gukora iki niba nciwe urugero rwa Clomipramine?

Niba wibagiwe gufata urugero, rufate uko wibukije vuba keretse igihe cyo gufata urugero rukurikira kigeze. Ntukigere ufata urugero ebyiri icyarimwe kugira ngo usimbure urugero wibagiwe, kuko ibyo bishobora gutera ingaruka mbi.

Niba ufata clomipramine rimwe ku munsi kandi ukaba waribagiwe urugero, urashobora kurufata nyuma y'amasaha 12. Niba urufata kabiri ku munsi, fata urugero wibagiwe niba bitarenze amasaha 6 uhereye igihe wagombaga kurufatiraho.

Nshobora guhagarika ryari gufata Clomipramine?

Wagombye guhagarika gufata clomipramine uyobowe na muganga wawe gusa, kabone niyo wumva umeze neza rwose. Abantu benshi bagomba kugabanya buhoro buhoro mu byumweru byinshi kugira ngo birinde ibimenyetso byo gukurwaho umuti.

Kubera OCD, abaganga benshi basaba gukomeza gufata umuti byibuze umwaka umwe nyuma y'uko ibimenyetso bigabanuka kugira ngo birinde gusubira inyuma. Muganga wawe azagufasha gufata icyemezo cy'igihe bikwiye kugerageza kugabanya cyangwa guhagarika umuti.

Nshobora kunywa inzoga nkanwa Clomipramine?

Ni byiza kwirinda inzoga nkanwa clomipramine, kuko bishobora kongera ibitotsi n'izindi ngaruka zikomeye. Ndetse n'inzoga ntoya zishobora gutuma wumva urushye cyane cyangwa uruka kurusha uko bisanzwe.

Niba uhisemo kunywa rimwe na rimwe, wigabanyirize ku bwinshi buto cyane kandi ntunywe na rimwe igihe utwaye imodoka cyangwa ukoresha imashini. Ganira na muganga wawe ku byo bifitiye umutekano imiterere yawe yihariye.