Icyo Dichlorphenamide ari cyo: Ibyo ikoreshwa, Urutonde rw'imiti, Ingaruka zayo n'ibindi

Dichlorphenamide ni umuti wandikirwa na muganga ufasha kugabanya amazi yiyongera mu maso yawe no mu bwonko bwawe. Uherereye mu cyiciro cy'imiti yitwa carbonic anhydrase inhibitors, ikora ibyo ikingira za enzymes zimwe na zimwe zigenzura imikorere y'amazi mu mubiri wawe.

Uyu muti ukoreshwa cyane cyane mu kuvura indwara zimwe na zimwe zo mu maso n'ubwoko bumwe na bumwe bwo kunanuka kw'imitsi. Nubwo atari umuti usanzwe ukoreshwa mu rugo, ushobora gufasha cyane abantu bahanganye n'ibibazo by'ubuzima byihariye bigira ingaruka ku miyoborere yabo cyangwa imikorere y'imitsi yabo.

Dichlorphenamide ikoreshwa mu kuvura iki?

Dichlorphenamide ivura glaucoma, indwara ikomeye yo mu maso aho umuvuduko wiyongera imbere mu jisho ryawe. Uyu muvuduko wiyongereye ushobora kwangiza imitsi yawe ya optique kandi bigatuma ubureba bugabanuka niba butavuwe.

Uyu muti ufasha kandi abantu bafite ubumuga bwa periodic paralysis, indwara idasanzwe itera ibihe byo kunanuka kw'imitsi. Muri ibi bihe, ushobora gusanga bigoye kugenda imitsi imwe na imwe, ibyo bishobora gutera ubwoba no kudashobora gukora.

Byongeye kandi, abaganga rimwe na rimwe bandika dichlorphenamide kubwoko bumwe na bumwe bwo gufatwa n'indwara no kugabanya guhura kw'ubwonko. Izi nyungu ntizisanzwe ariko zirashobora kurokora ubuzima mu bihe byihariye aho izindi nshuti zitagize akamaro.

Dichlorphenamide ikora ite?

Dichlorphenamide ikora ikingira enzymes za carbonic anhydrase mu mubiri wawe wose. Izi enzymes zisanzwe zifasha gukora amazi mu maso yawe, mu mpyisi zawe, no mu zindi ngingo.

Iyo umuti ukingiye izi enzymes, amazi make akorwa mu maso yawe, ibyo bigabanya umuvuduko imbere muri yo. Ibi ni ngombwa cyane ku barwayi ba glaucoma, kuko umuvuduko muto wo mu maso ufasha kurengera imitsi ya optique kwangirika.

Ku bantu bafite ubumuga bwa buri gihe, imiti ifasha gufata neza imikorere y'amashanyarazi mu ngirangingo z'imitsi. Iyi mikorere ifasha gukumira cyangwa kugabanya ubukana bw'ibihe byo guhagarara kw'imitsi, bikaguha ubushobozi bwo kugenzura imikorere y'imitsi yawe.

Birakwiye kumenya ko dichlorphenamide ifatwa nk'umuti ukomeye ku rugero ruciriritse. Iruta imbaraga izindi zihagarika carbonic anhydrase, bivuze ko ishobora kugira akamaro kanini ariko kandi bisaba gukurikiranwa neza na muganga wawe.

Nkwiriye Gufata Dichlorphenamide Nte?

Fata dichlorphenamide nk'uko muganga wawe abikwandikiye, akenshi inshuro 1-3 ku munsi hamwe n'ibiryo. Kuyifata hamwe n'ibiryo bifasha kugabanya isesemi kandi bigateza imbere uburyo umubiri wawe wunguka umuti.

Mimina ibinini byose hamwe n'ikirahure cyuzuye cy'amazi. Ntugasenya, utahe cyangwa ucagagure ibinini, kuko ibi bishobora kugira ingaruka ku buryo umuti ukora mu mubiri wawe.

Nibyiza gufata imiti yawe mu gihe kimwe buri munsi kugirango ugumane urwego rwo hejuru rw'umuti mu mubiri wawe. Niba ufata imiti myinshi, uyigabanye mu gihe kimwe kumunsi nkuko byategetswe n'umuganga wawe.

Gerageza kurya ifunguro rito cyangwa ifunguro rito mbere yo gufata dichlorphenamide, cyane cyane niba ufite igifu cyoroshye. Ibiryo byoroshye gucyurwa, nk'umugati cyangwa amandazi, bikora neza niba utumva ushaka kurya ifunguro ryuzuye.

Mbonye Kandi Nkwiriye Gufata Dichlorphenamide Igihe Kingana Gite?

Ubugufi bwo kuvurwa na dichlorphenamide biterwa rwose n'uburwayi bwawe bwihariye n'uburyo wunguka umuti. Abantu bamwe bakeneye kuyifata mu byumweru bike gusa, mu gihe abandi bashobora kuyikeneye mu mezi cyangwa imyaka.

Kubera glaucoma, birashoboka ko uzakenera kuvurwa igihe kirekire kugirango ugumane umuvuduko w'ijisho ryawe mu buryo bugenzurwa. Muganga wawe azagenzura umuvuduko w'ijisho ryawe buri gihe kandi ahindure gahunda yawe yo kuvura uko bikwiye.

Niba urimo gufata dichlorphenamide kubera ubumuga bwa buri gihe, igihe cyabyo gishobora gutandukana cyane. Abantu bamwe babona impinduka mu byumweru, mu gihe abandi bakeneye amezi menshi kugira ngo babone inyungu zose.

Ntuzigere uhagarika gufata dichlorphenamide ako kanya utabanje kuvugana na muganga wawe. Guhagarika ako kanya bishobora gutuma ibimenyetso byawe bisubira cyangwa bikiyongera, cyane cyane niba uvurwa indwara ya glaucoma.

Ni Ibihe Bikorwa Bigaragara Byo Ku Ruhande Bya Dichlorphenamide?

Kimwe n'imiti yose, dichlorphenamide ishobora gutera ibikorwa bigaragara ku ruhande, nubwo atari buri wese ubyumva. Ibikorwa bigaragara ku ruhande byinshi ni bike kandi birashobora gucungwa, ariko ni ngombwa kumenya icyo ugomba kwitaho.

Ibikorwa bigaragara ku ruhande bisanzwe ushobora guhura nabyo birimo kuribwa mu ntoki no mu birenge, impinduka mu buryohe, no kwihagarika cyane. Ibi bikorwa bibaho kuko umuti ugira ingaruka ku buryo umubiri wawe ukoresha imyunyu ngugu n'amazi.

Dore ibikorwa bigaragara ku ruhande byavuzwe kenshi abantu benshi bahura nabyo:

• Kuribwa cyangwa guhuma mu ntoki no mu birenge
• Uburyohe bw'icyuma mu kanwa kawe
• Kwihagarika cyane, cyane cyane mbere
• Uburwayi buke cyangwa kuribwa mu nda
• Kunanirwa cyangwa kumva unaniwe
• Kubura ubushake bwo kurya
• Kuribwa umutwe iyo uhagurutse

Ibi bikorwa bisanzwe bigaragara ku ruhande akenshi birakosoka uko umubiri wawe ukimenyereza umuti, akenshi mu byumweru bya mbere byo kuvurwa.

Abantu bamwe bashobora guhura n'ibikorwa bigaragara ku ruhande bikomeye bisaba ubufasha bwihutirwa bwa muganga. Nubwo ibi bitaba kenshi, ni ngombwa kubimenya:

• Ibibazo bikomeye by'impyiko hamwe no kwihagarika guke
• Ibimenyetso bya sodium nkeya mu maraso (urujijo, gufatwa)
• Ibikorwa bikomeye byo ku ruhu cyangwa ibibara
• Gusohoka amaraso cyangwa gukomereka bidasanzwe
• Uburwayi bukomeye bwo mu mutwe cyangwa impinduka z'imitekerereze
• Ibimenyetso by'ibibazo by'umwijima (guhinduka umuhondo kw'uruhu cyangwa amaso)

Niba uhuye n'ibikorwa bigaragara ku ruhande bikomeye, vugana na muganga wawe ako kanya cyangwa ushake ubufasha bwihutirwa bwa muganga.

Hariho kandi ingaruka zimwe na zimwe zitavugwa cyane ariko zishobora guteza ibibazo bikomeye zigaragara kuri bakeya batarenze 1% bafata dichlorphenamide:

• Kutaringanira kw'amazi n'imyunyu ngugu bikomeye bigira ingaruka ku mutima
• Urubuto rwo mu mpyiko
• Kugabanuka gukabije kw'umushongi wo mu magufa
• Glaucoma ikaze yo gufunga urugero (mu buryo butunguranye, kuri bamwe)
• Sindrome ya Stevens-Johnson (uburwayi bukomeye bwo ku ruhu)

Nubwo izi ngaruka zitavugwa cyane ziteye impungenge, wibuke ko muganga wawe yaguhaye uyu muti kuko yizeye ko inyungu ziruta ibyago mu miterere yawe.

Ni bande batagomba gufata Dichlorphenamide?

Dichlorphenamide ntiboneye kuri buri wese, kandi hariho ibibazo bitandukanye bituma uyu muti utabereye cyangwa ushobora guteza akaga.

Ntabwo ugomba gufata dichlorphenamide niba ufite indwara ikomeye y'impyiko, indwara y'umwijima, cyangwa kutaringanira kw'amazi n'imyunyu ngugu. Ibi bibazo bishobora gutuma umubiri wawe utabasha gukora imiti neza.

Abantu bafite allergie zimwe na zimwe bagomba kwirinda uyu muti. Niba ufite allergie ku miti ya sulfa, ibiyobyabwenge bya carbonic anhydrase, cyangwa ibintu byose biri muri dichlorphenamide, ntugomba kuyifata.

Dore ibibazo by'ingenzi bisanzwe bibuza umuntu gufata dichlorphenamide mu buryo bwizewe:

• Indwara ikomeye y'impyiko cyangwa kunanirwa kw'impyiko
• Indwara ikomeye y'umwijima cyangwa kunanirwa kw'umwijima
• Urugero rwo hasi rwa sodium mu maraso yawe
• Urugero rwo hasi rwa potasiyumu mu maraso yawe
• Indwara ikomeye y'ibihaha (nka COPD)
• Glaucoma yo gufunga urugero (ubwoko bwihariye)
• Allergie izwi ku miti ya sulfa

Muganga wawe azagomba gukoresha ubushishozi bwihariye kandi akugenzure neza niba ufite diyabete, indwara y'umutima, cyangwa osteoporosis, kuko dichlorphenamide ishobora kugira ingaruka kuri ibi bibazo.

Inda no konsa amabere na byo bisaba kwitonderwa byihariye. N'ubwo bitazwi ko dichlorphenamide itera ubumuga ku bana bavuka, ntibisabwa kuyikoresha mu gihe cyo gutwita keretse bibaye ngombwa rwose. Niba utwite cyangwa uteganya gutwita, ganira na muganga wawe ku byiza n'ibibi byabyo.

Amazina y'ubwoko bwa Dichlorphenamide

Dichlorphenamide iboneka ku izina ry'ubwoko rya Keveyis muri Leta Zunze Ubumwe z'Amerika. Iri ni ryo zina ry'ubwoko rya dichlorphenamide risabwa cyane.

Mu bindi bihugu, dichlorphenamide ishobora kuboneka ku mazina y'ubwoko atandukanye cyangwa nk'umuti rusange. Ariko, uko iboneka biratandukana cyane bitewe n'aho uherereye.

Niba uri mu rugendo cyangwa wimukiye mu kindi gihugu, reba muri farumasi zo mu gace kawe cyangwa abaganga ku bijyanye n'uko iboneka, kuko uyu muti ntuboneka hose ku isi.

Izindi miti isimbura Dichlorphenamide

Imiti myinshi ishobora kuvura indwara zimwe na zimwe nka dichlorphenamide, nubwo ishobora gukora mu buryo butandukanye cyangwa ikagira ingaruka zitandukanye.

Ku ndwara ya glaucome, izindi miti ikumira carbonic anhydrase nka acetazolamide (Diamox) cyangwa amavuta yo mu maso ya dorzolamide bishobora kuba amahitamo. Imiti ikumira beta nka timolol cyangwa analogs ya prostaglandin nka latanoprost na byo bikoreshwa cyane.

Ku ndwara ya paralysie periodique, acetazolamide akenshi ifatwa nk'umuti wa mbere. Abantu bamwe kandi bungukirwa no kongerwa kwa potasiyumu cyangwa guhindura imirire, bitewe n'ubwoko bwabo bwihariye bwa paralysie periodique.

Muganga wawe azatekereza ku bintu nk'indwara yawe yihariye, izindi ngorane z'ubuzima, n'uko wihanganira imiti itandukanye mu gihe ahitamo uburyo bwiza bwo kukuvura.

Ese Dichlorphenamide iruta Acetazolamide?

Dichlorphenamide na acetazolamide zombi ni imiti ikumira carbonic anhydrase, ariko zifite itandukaniro rikomeye rishobora gutuma imwe ikugirira akamaro kurusha indi.

Dichlorphenamide ikunda kumara igihe kirekire mu mubiri, bivuze ko ushobora gukenera kuyifata gake ugereranyije na acetazolamide. Ibi bishobora koroha kandi bikongerera ubwitange mu kunywa imiti.

Ariko, acetazolamide imaze igihe kinini ikoreshwa kandi iboneka mu buryo bwinshi, harimo n'urushinge rukoreshwa mu gihe cy'uburwayi bwihutirwa. Ikindi kandi, akenshi ihendutse ugereranyije na dichlorphenamide.

Ku bijyanye n'ugutumuka kwa hato na hato, ubushakashatsi bumwe buvuga ko dichlorphenamide ishobora kugira akamaro mu gukumira ibitero, ariko uko umuntu abyakira biratandukana cyane. Icyo gikora neza ku muntu umwe gishobora kutagira akamaro ku wundi.

Muganga wawe azatekereza ku bimenyetso byawe byihariye, imiti yindi urimo gufata, n'ubuzima bwawe muri rusange mu gihe afata icyemezo cy'umuti ukwiriye kuri wowe.

Ibibazo Bikunze Kubazwa Kuri Dichlorphenamide

Q1. Ese Dichlorphenamide irakwiriye abarwayi ba diyabete?

Dichlorphenamide irashobora gukoreshwa n'abantu barwaye diyabete, ariko bisaba gukurikiranwa neza. Uyu muti ushobora kugira ingaruka ku isukari yo mu maraso yawe kandi ushobora gufatanya n'imiti imwe ya diyabete.

Muganga wawe ashobora gushaka gupima isukari yo mu maraso yawe kenshi iyo utangiye gufata dichlorphenamide. Ashobora kandi gukenera guhindura imiti yawe ya diyabete kugira ngo ugumane isukari yo mu maraso neza.

Wibuke kubwira muganga wawe imiti yose yawe ya diyabete, harimo na insuline, mu gihe muganira ku kuvurwa na dichlorphenamide.

Q2. Nkwiriye gukora iki niba mfashe dichlorphenamide nyinshi mu buryo butunganye?

Niba ufashe dichlorphenamide nyinshi, vugana na muganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. Ntukegere ngo urebe niba ibimenyetso bigaragara, kuko kunywa umuti mwinshi bishobora kuba bikomeye.

Ibimenyetso byo kunywa umuti mwinshi bishobora kuba birimo isesemi ikabije, kuruka, urujijo, umunaniro ukabije, cyangwa guhumeka bigoye. Mu bihe bikomeye, bishobora kugira ingaruka ku mutima wawe cyangwa imikorere y'impyiko.

Niba hari umuntu utazi ibibera cyangwa ufite ikibazo cyo guhumeka nyuma yo kunywa dichlorphenamide nyinshi cyane, hamagara serivisi zihutirwa ako kanya.

Q3. Nkwiriye gukora iki niba nciwe doze ya Dichlorphenamide?

Niba wibagiwe doze, yifate uburyo wibukira, keretse igihe cyegereje doze yawe itaha. Muri icyo gihe, reka doze wibagiwe ukomeze gahunda yawe isanzwe.

Ntukanywe doze ebyiri icyarimwe kugirango usimbure doze wibagiwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka ziterwa n'imiti. Kunywa imiti y'inyongera ntibizasimbura doze wibagiwe kandi bishobora guteza akaga.

Niba ukunda kwibagirwa doze, tekereza gushyiraho ibyibutso kuri terefone cyangwa gukoresha umuteguro w'imiti kugirango ugufashe kuguma kuri gahunda yawe y'imiti.

Q4. Nshobora guhagarika ryari kunywa Dichlorphenamide?

Ntuzigere uhagarika kunywa dichlorphenamide utabanje kuvugana na muganga wawe, kabone n'iyo wumva umeze neza. Guhagarika mu buryo butunguranye bishobora gutuma ibimenyetso byawe bisubira cyangwa bikiyongera.

Muganga wawe azagena igihe cyiza cyo guhagarika bitewe n'uburwayi bwawe n'uburyo urimo kwitwara neza ku miti. Ku burwayi bumwe na bumwe nka glaucome, ushobora gukenera kunywa umuti igihe kirekire.

Niba ufite ingaruka ziterwa n'imiti cyangwa ushaka guhagarika umuti, ganira ibibazo byawe na muganga wawe. Bashobora guhindura doze yawe cyangwa bakaguherereza undi muti.

Q5. Nshobora kunywa inzoga nkanwa Dichlorphenamide?

Nibyiza kugabanya kunywa inzoga nkanwa dichlorphenamide, kuko inzoga ishobora kongera ingaruka zimwe na zimwe zirimo isereri no gusinzira. Ubu buryo bushobora no kugira ingaruka ku mitsi yawe y'amaraso.

Niba uhisemo kunywa inzoga, bikore mu rugero kandi umenye ko ushobora kumva ingaruka zikomeye kuruta uko byari bisanzwe. Witondere uko wumva kandi wirinde ibikorwa bisaba ubushishozi, nko gutwara imodoka.

Ganira na muganga wawe ku bijyanye n'uko unywa inzoga kugira ngo aguhe inama zigenewe wowe ku giti cyawe zishingiye ku miterere yawe bwite n'imiti yindi ushobora kuba ufata.