Icyo Diethylcarbamazine ari cyo: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'ibindi

Diethylcarbamazine ni umuti wandikirwa na muganga urwanya iminyorogoto mu mubiri wawe. Yagenewe by'umwihariko kuvura indwara ziterwa n'iminyorogoto imwe n'imwe n'udukoko duto duto dushobora kwibasira imitsi yawe, amaraso, n'ibice by'umubiri. Uyu muti umaze imyaka myinshi ufasha abantu koroherwa n'indwara ziterwa n'iminyorogoto kandi ukaba ukiri umwe mu miti ikora neza cyane.

Diethylcarbamazine ni iki?

Diethylcarbamazine ni umuti urwanya iminyorogoto wo mu cyiciro cy'imiti yitwa anthelmintics. Wibuke ko ari umuti ugenda wihariye ukica iminyorogoto iba mu mubiri wawe. Uyu muti ukora uhagarika iminyorogoto, akayica, bityo urugingo rwawe rw'umubiri rukarwanya indwara rukayikiza.

Uyu muti uza mu buryo bw'ibinini kandi ufata mu kanwa. Umaze imyaka myinshi ukoreshwa neza kandi ufatwa nk'umuti mwiza wo kuvura indwara ziterwa n'iminyorogoto imwe n'imwe. Uyu muti ukora neza cyane ku microfilariae, ari zo udusimba duto duto tw'iminyorogoto dukwirakwira mu maraso yawe.

Diethylcarbamazine ikoreshwa mu kuvura iki?

Diethylcarbamazine ivura indwara zimwe na zimwe ziterwa n'iminyorogoto zibasira abantu babarirwa muri za miliyoni ku isi hose. Uyu muti wandikirwa cyane cyane indwara ya filariyasi ya limfatike, izwi kandi ku izina rya elephantiasis, iterwa n'iminyorogoto isa n'udushumi ifunga imitsi yawe ya limfatike.

Uyu muti kandi uvura neza loiasis, indwara iterwa n'umunyorogoto wo mu jisho rya Afurika ushobora kwimukira munsi y'uruhu rwawe rimwe na rimwe ukambukiranya ijisho ryawe. Byongeye kandi, ukoreshwa mu kuvura eosinophilia yo mu bihaha by'ubushyuhe, indwara yo mu bihaha iterwa n'uburyo urugingo rwawe rw'umubiri rwitwara ku minyorogoto ya filariyali.

Mu buryo butajyenda cyane, abaganga bashobora kwandika imiti ya diethylcarbamazine kubera izindi ndwara ziterwa na parasite nka visceral larva migrans, aho iminyorogoto y'iminyorogoto yimuka mu ngingo zawe. Muganga wawe azemeza niba uyu muti ukwiriye indwara yawe yihariye hashingiwe ku bizami byo muri laboratori n'ibimenyetso byawe.

Diethylcarbamazine ikora ite?

Diethylcarbamazine ifatwa nk'umuti urwanya parasite ukomeye cyane ukora mu buryo bwinshi. Uyu muti uvangira imikorere y'imitsi ya parasite, bituma zihagarara gukora hanyuma zigapfa. Binatuma parasite zigaragara cyane ku mikorere y'umubiri wawe, bifasha umubiri wawe kwikuramo neza.

Uyu muti ukora neza cyane ku microfilariae, iminyorogoto mito mito izunguruka mu maraso yawe. Iyo izi parasite zipfuye, zirekura ibintu bishobora gutera ibimenyetso byo mu mubiri. Ibi nibyo bituma abantu bamwe bagira ingaruka mbi iyo batangira kuvurwa, kuko umubiri wabo usubiza ku parasite zipfa.

Uyu muti ugera ku rwego rwo hejuru mu maraso yawe mu isaha imwe cyangwa ebyiri nyuma yo kuwufata kandi ukomeza gukora amasaha menshi. Umubiri wawe ukora kandi ukavana uyu muti mu mubiri unyuze mu mpyisi zawe, niyo mpamvu abantu bafite ibibazo by'impyisi bashobora gukenera doze zihinduka.

Nkwiriye gufata Diethylcarbamazine nte?

Fata diethylcarbamazine nkuko muganga wawe abitegeka, akenshi hamwe cyangwa nyuma yo kurya kugirango ugabanye ibibazo byo mu nda. Uyu muti akenshi ufashwa inshuro 2-3 ku munsi mu minsi myinshi kugeza ku byumweru, bitewe n'indwara yawe yihariye n'uburyo umubiri wawe usubiza ku buvuzi.

Mimina ibinini byose hamwe n'ikirahure kinini cy'amazi. Gufata uyu muti hamwe n'ibiryo bifasha umubiri wawe kuwufata neza kandi bigabanya amahirwe yo kuruka cyangwa kutumva neza mu nda. Abaganga bamwe basaba kuwufata hamwe n'amata cyangwa ifunguro rito niba ufite ibibazo byo mu nda.

Muganga wawe ashobora gutangira kugutera urugero ruto hanyuma akagenda arwongera buhoro buhoro mu minsi ya mbere. Ubu buryo bufasha kugabanya ingaruka ziterwa nuko imibare minini y'udukoko twica vuba. Ntukigere na rimwe usiba imiti cyangwa guhagarika gufata imiti hakiri kare, kabone niyo wumva urushijeho, kuko ibi bishobora gutuma ubuvuzi butagera ku ntego.

Nzamara Igihe Kingana Gite Ndafata Diethylcarbamazine?

Igihe cyo kuvurwa na diethylcarbamazine gitandukanye cyane bitewe n'ubwandu bw'udukoko wihariye ufite. Kubera filariasis ya lymphatic, ushobora gufata umuti mu minsi 12-21, mugihe loiasis isaba ubuvuzi bw'ibyumweru 2-3.

Muganga wawe azagenzura uko urimo utera imbere binyuze mu bizami by'amaraso no kugenzura umubiri kugirango amenye igihe byemewe guhagarika ubuvuzi. Abantu bamwe bashobora gukenera uburyo bwinshi bwo kuvurwa butandukanye mu byumweru cyangwa amezi kugirango bakureho burundu ubwandu.

Kubera eosinophilia ya pulmonary tropique, ubuvuzi busanzwe bumara ibyumweru 2-3, ariko muganga wawe ashobora kubwongera bitewe n'ibimenyetso byawe n'ibisubizo by'ibizamini. Kora ubuvuzi bwose kabone niyo utangiye kumva urushijeho, kuko guhagarika hakiri kare bishobora korohereza udusimba dusigaye kwiyongera no gutuma ubwandu bugaruka.

Ni Iyihe Ngaruka Ziterwa na Diethylcarbamazine?

Ingaruka ziterwa na diethylcarbamazine zikunze kubaho kuko urwego rwawe rw'ubudahangarwa rwitabira udusimba dupfira mu mubiri wawe. Abantu benshi bahura n'akababaro gato mu minsi ya mbere yo kuvurwa, ariko izi ngaruka zikunze gukira uko umubiri wawe wimenyereza umuti.

Ingaruka zisanzwe abantu benshi bahura nazo zirimo:

• Umutwe no kuribwa
• Isesemi no kuruka
• Urubavu n'ubukonje
• Urubavu rw'imitsi n'amagufwa
• Kunanirwa no gucika intege
• Kubura ubushake bwo kurya

Ibi bimenyetso akenshi bigera ku rwego rwo hejuru mu minsi 2-3 ya mbere yo kuvurwa hanyuma bigenda bigabanuka buhoro buhoro. Muganga wawe ashobora kugusaba imiti igurishwa idakeneye uruhushya cyangwa imiti irwanya ububyimbirwe kugira ngo ifashe mu kugabanya izo ngaruka.

Ingaruka zikomeye zishobora kubaho, cyane cyane ku bantu bafite indwara ziterwa na parasite zikomeye. Izi ngaruka zibaho iyo umubare munini wa parasite upfuye icyarimwe, ukarekurira ibintu bitera ububyimbirwe mu maraso yawe.

Ingaruka zikomeye zisaba ubufasha bwihuse bw'abaganga zirimo:

• Uburwayi bukomeye bwo kwivumbura ku bintu bitera allergie hamwe no guhumeka bigoranye cyangwa kubyimba
• Uburibwe bukomeye mu maso cyangwa impinduka mu mbono
• Uburibwe bukomeye mu nda
• Kugorana kwihagarika cyangwa amaraso mu nkari
• Kugira ibibazo byo gufatwa n'indwara cyangwa urujijo rukomeye
• Uburibwe mu gituza cyangwa umutima utera nabi

Abantu bafite indwara ya loiasis bashobora guhura n'ingaruka zidasanzwe iyo iminyorogoto ikuru ipfiriye mu duce tworoheje nk'amaso cyangwa ubwonko. Muganga wawe azagukurikiranira hafi niba ufite ubu bwoko bw'indwara.

Ninde utagomba gufata Diethylcarbamazine?

Diethylcarbamazine ntikwiriye buri wese, kandi muganga wawe azasuzuma neza amateka yawe y'ubuzima mbere yo kuyandika. Abantu bafite indwara zimwe na zimwe bashobora guhura n'ibibazo byiyongera cyangwa ingorane zituruka kuri uyu muti.

Ntabwo ukwiriye gufata diethylcarbamazine niba ufite:

• Allergie izwi kuri diethylcarbamazine cyangwa imiti isa nayo
• Indwara ikomeye y'impyiko cyangwa kunanirwa kw'impyiko
• Indwara z'amaso zikora cyangwa kubagwa mu maso vuba aha
• Indwara zikomeye z'umutima cyangwa umuvuduko w'amaraso udagenzurwa
• Indwara zikora zo gufatwa n'indwara

Ubwitange bwihariye bukenewe ku matsinda amwe na amwe y'abantu. Abagore batwite bakwiriye gufata uyu muti gusa niba inyungu ziruta neza ibyago, kuko umutekano mu gihe cyo gutwita utarashyirwaho neza. Abagore bonsa bakwiriye kuganira n'abaganga babo ku bindi bisubizo, kuko uyu muti ushobora kujya mu mata y'ibere.

Abantu barwaye onchocerciasis (ubuhumyi bw'umugezi) ntibagomba na rimwe gufata diethylcarbamazine, kuko bishobora guteza ibibazo bikomeye by'amaso n'ubuhumyi. Muganga wawe azagupima iyi ndwara mbere yo gutangira kuvurwa. Abana bari munsi y'imyaka 4 akenshi bahabwa imiti ikurikije uburemere bwabo n'imyaka yabo.

Amazina y'ubwoko bwa Diethylcarbamazine

Diethylcarbamazine iboneka mu mazina y'ubwoko atandukanye bitewe n'aho uherereye n'aho ufite farumasi. Izina risanzwe ni Hetrazan, ryakoreshejwe mu myaka myinshi ishize mu kuvura indwara ziterwa na parasite ku isi hose.

Andi mazina y'ubwoko arimo Banocide na Carbilazine, nubwo iboneka bitandukanye bitewe n'igihugu n'akarere. Mu turere tumwe na tumwe, umuti uboneka gusa mu buryo rusange, bukora neza nk'ubwoko bw'izina.

Farumasi yawe ishobora kugira ubwoko butandukanye cyangwa ubwoko rusange bwa diethylcarbamazine. Imiti yose yemejwe irimo ikintu kimwe gikora kandi itanga ingaruka zingana zo kuvura, bityo urashobora guhindura ubwoko mu buryo bwizewe niba bibaye ngombwa.

Uburyo bwo kuvura bundi bwa Diethylcarbamazine

Imiti myinshi isimbura ishobora kuvura indwara ziterwa na parasite, nubwo guhitamo neza biterwa n'uburwayi bwawe bwihariye n'amateka yawe y'ubuvuzi. Muganga wawe azahitamo uburyo bwo kuvura bukwiye cyane bitewe n'ubwoko bwa parasite n'imibereho yawe bwite.

Muri filariasis ya lymphatic, ivermectin ihujwe na albendazole yabaye uburyo bwo kuvura busanzwe. Ubu buryo bukunze gukoreshwa muri gahunda zo kuvura abantu benshi kandi bushobora gufasha abantu batabasha kwihanganira diethylcarbamazine.

Muri loiasis, ivermectin yonyine irashobora gukoreshwa, nubwo bisaba gukurikiranwa neza kuko bishobora gutera ibibazo iyo parasite zipfuye. Albendazole ni ubundi buryo bwo kuvura indwara zimwe ziterwa na parasite, cyane cyane izijyanye n'inzoka zo mu mara.

Imiti mishya nka doxycycline irimo kwigwaho mu kuvura indwara ziterwa na filariya hagamijwe kwibasira bagiteri ziba mu nzoka ziterwa na parasite. Muganga wawe azaganira kuri izi nzira niba diethylcarbamazine itagukwiriye.

Ese Diethylcarbamazine iruta Ivermectin?

Byombi, diethylcarbamazine na ivermectin ni imiti ikora neza mu kurwanya parasite, ariko zikora mu buryo butandukanye kandi zikwiriye mu bihe bitandukanye. Guhitamo hagati yazo biterwa n'ubwandu bwihariye ufite, amateka yawe y'ubuzima, n'intego z'ubuvuzi.

Diethylcarbamazine muri rusange ikora neza mu kwica inzoka zikuru ziterwa na parasite, bigatuma ariyo ihitwamo cyane mu bwandu bumaze gushinga aho ushaka gukuraho parasite burundu. Ifite amateka maremare yo gukoreshwa kandi hariho ubushakashatsi bwinshi bushyigikira imikorere yayo.

Ivermectin akenshi ikunda gukoreshwa mu gukumira ikwirakwizwa rya parasite ku bandi, kuko ikora neza mu kwica microfilariae mu maraso. Irashobora gutera ibimenyetso bike bikomeye ku bantu bamwe, cyane cyane abafite ubwandu bukomeye.

Muganga wawe azatekereza ku bintu nk'ubwoko bwa parasite, ubukana bw'ubwandu, ubuzima bwawe muri rusange, n'amabwiriza y'ubuvuzi bwaho mugihe ahitamo hagati yiyi miti. Gahunda zimwe na zimwe z'ubuvuzi zikoresha imiti yombi icyarimwe kugirango zikore neza cyane.

Ibikunze Kubazwa Kuri Diethylcarbamazine

Q1. Ese Diethylcarbamazine irakwiriye ku bantu barwaye indwara z'umutima?

Abantu barwaye indwara z'umutima akenshi bashobora gufata diethylcarbamazine neza, ariko bakeneye gukurikiranwa cyane mugihe cy'ubuvuzi. Iyi miti rimwe na rimwe ishobora gutera impinduka mu mutima cyangwa umuvuduko w'amaraso, cyane cyane iyo parasite zipfuye zigahita zirekura ibintu bitera umubiri kubyimba.

Muganga wawe azasuzuma uko umutima wawe umeze mbere yo gutangira kuvurwa, kandi ashobora kugusaba gukurikiranwa cyangwa guhabwa imiti yongera kurinda imitsi yawe. Niba ufite uburwayi bukomeye bw'umutima cyangwa warwaye umutima vuba aha, muganga wawe ashobora guhitamo izindi nzira zo kuvura cyangwa agahindura urugero rw'umuti ukoresha.

Q2. Nakora iki niba nanyweye Diethylcarbamazine nyinshi ku buryo butunguranye?

Niba unyweye Diethylcarbamazine nyinshi ku buryo butunguranye, vugana n'umuganga wawe cyangwa ikigo gishinzwe ubumara ako kanya. Kunywa umuti mwinshi bishobora kongera ibyago byo kugira ingaruka zikomeye, harimo gufatwa n'ibibazo by'ubwonko, ibibazo bikomeye by'uburwayi, n'ibibazo by'imitsi y'umutima.

Ntugerageze kwivugisha umuriro keretse niba ubisabwe n'abaganga. Ahubwo, gerageza kumenya urugero rw'umuti wanyoye n'igihe wanyweye, hanyuma ushake ubufasha bw'ubuvuzi ako kanya. Ibibazo byinshi byo kunywa umuti mwinshi bishobora gukemurwa neza n'ubuvuzi bukwiriye.

Q3. Nakora iki niba nibagiwe kunywa urugero rwa Diethylcarbamazine?

Niba wibagiwe kunywa urugero rwa Diethylcarbamazine, unywe ako kanya wibukiye, keretse igihe cyo kunywa urugero rukurikira kigeze. Mu gihe bimeze bityo, reka urugero wibagiwe hanyuma ukomeze gahunda yawe isanzwe yo kunywa imiti.

Ntunyweho urugero rwa kabiri icyarimwe kugira ngo usimbure urugero wibagiwe, kuko ibi bishobora kongera ibyago byo kugira ingaruka zikomeye. Niba ukunda kwibagirwa kunywa imiti, tekereza gushyiraho ibyibutsa cyangwa kunywa umuti wawe mu gihe kimwe buri munsi hamwe n'ifunguro.

Q4. Nshobora kureka kunywa Diethylcarbamazine ryari?

Reka kunywa Diethylcarbamazine gusa mugihe muganga wawe akubwiye ko byemewe. Kureka kuvurwa kare cyane bishobora korohereza parasite zisigaye kwiyongera no gutuma ubwandu bwawe bugaruka, bishobora gutuma birushya kuvurwa.

Muganga wawe azakoresha ibizamini by'amaraso, ibizamini by'umubiri, no gukurikirana ibimenyetso kugira ngo amenye igihe wamariye kuvurwa neza. Abantu bamwe bakeneye ibizamini byo gukurikirana amezi menshi nyuma yo kuvurwa kugira ngo bamenye neza ko iyi ndwara yashize burundu.

Q5. Nshobora kunywa inzoga niba ndimo gufata Diethylcarbamazine?

Nibyiza kwirinda inzoga mugihe ufata diethylcarbamazine, kuko inzoga ishobora kongera ibyago byo kugira ingaruka zirimo isereri, isesemi, no kuribwa munda. Inzoga kandi ishobora kubangamira ubushobozi bw'umubiri bwo kurwanya indwara ziterwa na parasite.

Niba uhisemo kunywa inzoga rimwe na rimwe, wikwiriza gusa, kandi ukurikirane uko wumva. Hagarika kunywa ako kanya niba ubonye ingaruka zikomeye cyangwa wumva utameze neza. Buri gihe ganira ku kunywa inzoga na muganga wawe, cyane cyane niba ufite ibibazo by'umwijima cyangwa impyiko.