Disopyramide ni iki: Ibikoreshwa, Urutonde rw'imiti, Ingaruka ziterwa n'iyo miti n'ibindi

Disopyramide ni umuti w'umutima wandikirwa na muganga ufasha kugenzura umuvuduko w'umutima utari wo. Uyu muti ubarirwa mu cyiciro cy'imiti yitwa antiarrhythmics, ikora igihe igenzura ibimenyetso by'amashanyarazi mu mutima wawe kugira ngo isubize umutima mu murimo usanzwe, utuje.

Uyu muti umaze imyaka myinshi ukoreshwa mu kuvura indwara zitandukanye z'umutima. Muganga wawe ashobora kukwandikira uyu muti igihe umutima wawe utera cyane, cyangwa buhoro cyane, cyangwa mu buryo butajegajega bushobora gushyira ubuzima bwawe mu kaga.

Disopyramide ni iki?

Disopyramide ni umuti wo mu cyiciro cya IA antiarrhythmic ugabanya imikorere y'amashanyarazi mu mutima wawe. Ukora ubu ukoma mu nkokora inzira zimwe na zimwe za sodium mu mikaya y'umutima wawe, ibi bikaba bifasha kugabanya no kugenzura ibimenyetso by'amashanyarazi bidahwitse.

Uyu muti uboneka mu buryo bwo gufata ako kanya n'uburyo bwo gufata buhoro buhoro. Muganga wawe azahitamo uburyo bukugirira neza bitewe n'uburwayi bwawe n'uburyo umubiri wawe witwara ku miti.

Tekereza umutima wawe nk'ikoresho ry'amashanyarazi mu rugo rwawe. Iyo insinga zidakora neza, amatara ashobora kuzima cyangwa ibikoresho ntibishobore gukora neza. Disopyramide ikora nk'igikoresho gishobora kugabanya amashanyarazi, ifasha kunoza ibyo bimenyetso bitajegajega kugira ngo umutima wawe utere mu buryo butuje kandi bukurikiza gahunda.

Disopyramide ikoreshwa mu kuvura iki?

Disopyramide ikoreshwa cyane cyane mu kuvura indwara ziteye ubuzima bw'umuntu akaga zifitanye isano n'umuvuduko w'umutima. Izi ni indwara z'umutima ziteye akaga zitangirira mu byumba byo hepfo by'umutima wawe kandi zishobora kwica umuntu igihe zitavuwe.

Muganga wawe ashobora kugusaba uyu muti niba ufite ventricular tachycardia ikomeye, aho umutima wawe utera cyane mu buryo buteye akaga. Ikoreshwa kandi mu bwoko bumwe na bumwe bwa ventricular fibrillation, umuvuduko w'umutima utajegajega utuma umutima wawe utohereza amaraso neza.

Mu bindi bihe, abaganga bandika disopyramide ku bantu bafite indwara ya hypertrophic cardiomyopathy, indwara aho imitsi y'umutima wawe iba yarakomeye cyane. Uyu muti ushobora gufasha kugabanya imbogamizi mu mutima wawe no kunoza ibimenyetso nk'ububabare mu gituza no guhumeka bigoranye.

Mu buryo butajegajega, ushobora gukoreshwa ku ndwara zimwe na zimwe z'umutima, nubwo ibi bikunze kuba iyo indi miti itagukoreye neza. Umuganga w'umutima wawe azasuzuma neza niba disopyramide ari wo muti ukwiriye ku ndwara y'umutima wawe.

Disopyramide ikora ite?

Disopyramide ifatwa nk'umuti ukomeye wo kurwanya indwara z'umutima. Ikora ibyo ikoresheje guhagarika imiyoboro yihuta ya sodium mu ngirangingo z'umutima wawe, ibyo bigatuma imikorere y'amashanyarazi ituma umutima utera igabanuka.

Iyo umutima wawe uteye mu buryo butari busanzwe, akenshi biterwa n'uko ibimenyetso by'amashanyarazi bigenda vuba cyangwa mu buryo butunganye mu ngirangingo z'umutima wawe. Disopyramide ifasha kugabanya ibi bimenyetso kandi ikabitegura neza, nk'umugenzi w'imodoka uyobora imihanda yuzuye.

Uyu muti kandi ufite icyo abaganga bita

Ushobora gufata uyu muti urya cyangwa utarya, ariko gerageza kubikora buri gihe. Niba uyu muti utuma wumva nabi mu gifu, kuwufata urya ifunguro rito cyangwa agafunguro gato birashobora kugufasha kugabanya ibibazo byo mu gifu.

Minya ibinini byose hamwe n'ikirahure cyuzuye cy'amazi. Ntugasenye, ntukore cyangwa ufungure ibinini, cyane cyane ubwoko burekura umuti buhoro buhoro, kuko ibi bishobora gutuma umuti mwinshi usohoka icyarimwe.

Gerageza gufata imiti yawe ku masaha amwe buri munsi kugira ngo ugumane urugero rwawo mu maraso yawe. Gushyiraho ibyibutsa kuri terefone birashobora kugufasha gukurikiza gahunda yawe yo gufata imiti.

Niba ufata ubwoko burekura umuti buhoro buhoro, irinde kunywa inzoga kuko bishobora kugira ingaruka ku buryo umuti winjizwa mu mubiri wawe. Nanone, witondere ibishyimbo na jus y'ibishyimbo, kuko ibi bishobora kugirana imikoranire n'imiti myinshi y'umutima.

Nzagomba Gufata Disopyramide Igihe Kingana Gite?

Igihe cyo kuvura na disopyramide gitandukana cyane bitewe n'uburwayi bw'umutima bwawe bwihariye n'uburyo wemera umuti. Abantu bamwe barawukeneye mu mezi make gusa, mu gihe abandi bashobora gukenera kuvurwa igihe kirekire.

Kubijyanye n'imikorere mibi y'umutima, muganga wawe ashobora kuwandikira igihe gito mugihe akurikirana uko umutima wawe witwara. Niba imikorere mibi igabanutse kandi ntigaruke, ushobora guhagarika umuti buhoro buhoro.

Ariko, niba ufite uburwayi burambye nk'umutima wa hypertrophic, ushobora gukenera gufata disopyramide imyaka myinshi cyangwa itagira iherezo. Muganga wawe azagenzura buri gihe niba inyungu zigikomeza kurenza ibyago byose bishoboka.

Ntuzigere uhagarika gufata disopyramide ako kanya utabanje kuvugana na muganga wawe. Guhagarika ako kanya bishobora gutuma ibibazo byawe by'umutima bisubira, rimwe na rimwe bikaba bikomeye kurusha mbere. Muganga wawe azakora gahunda yo kugabanya umuti niba bikwiye.

Ni Iyihe Miterere Ibaho ya Disopyramide?

Kimwe n'imiti yose, disopyramide ishobora gutera ingaruka zidakunda, nubwo atari buri wese uzagira izo ngaruka. Ingaruka zikunze kugaragara zifitanye isano n'imikorere ya anticholinergic y'uyu muti n'ingaruka zayo ku mutima wawe.

Dore ingaruka zikunze kuvugwa cyane ushobora guhura nazo:

• Umunwa n'umuhogo byumye
• Kureba nabi cyangwa kugorana kureba neza
• Kubura kwituma
• Kugorana kunyara cyangwa kubika inkari
• Isesemi cyangwa kuribwa mu nda
• Urugero cyangwa kumva umutwe
• Umunaniro cyangwa intege nke

Izi ngaruka zisanzwe akenshi zikunda gukira uko umubiri wawe wimenyereza umuti. Kuguma unywa amazi menshi no gukoresha chingamu idafite isukari cyangwa ibinini bishobora gufasha mu gihe umunwa wumye.

Ingaruka zikomeye zirashobora kubaho, nubwo zitabaho kenshi. Izi zikeneye ubufasha bwihutirwa bw'abaganga kandi zikubiyemo:

• Ibibazo bishya cyangwa bikomeye by'umuvuduko w'umutima
• Urugero rukabije cyangwa guta igihagararo
• Uburibwe mu gituza cyangwa kugorana guhumeka
• Ukubura mu maguru, mu birenge, cyangwa mu birenge
• Uburibwe bukomeye mu nda
• Ibimenyetso by'isukari nkeya mu maraso (kuriya, guhinda umushyitsi, urujijo)

Niba ubonye kimwe muri ibi bimenyetso bikomeye, vugana n'umuganga wawe ako kanya cyangwa ushake ubufasha bwihutirwa bw'abaganga.

Gahoro, disopyramide ishobora gutera ingaruka zikomeye cyane nk'uko guhagarara gukabije k'umutima, kugabanuka gukabije kw'umuvuduko w'amaraso, cyangwa ibimenyetso bikabije byo kwivumbura ku miti. Umuganga wawe azakugenzura neza, cyane cyane igihe utangiye kuvurwa, kugirango arebe ibi bibazo bidasanzwe ariko bikomeye.

Ninde utagomba gufata Disopyramide?

Disopyramide ntabwo ari nziza kuri buri wese, kandi umuganga wawe azasuzuma neza amateka yawe y'ubuvuzi mbere yo kuyandika. Ibyiciro bimwe na bimwe bituma uyu muti ushobora kuba uteje akaga cyangwa utagira akamaro.

Ntabwo ugomba gufata disopyramide niba ufite umutima udakora neza cyane, kuko uyu muti ushobora gutuma umutima wawe utabasha gutera amaraso neza. Ntibigirwa inama kandi niba ufite ubwoko runaka bwo guhagarara k'umutima udafite pacemaker.

Abantu bafite glaucoma bagomba kwirinda disopyramide kuko ingaruka zayo za anticholinergic zishobora kongera umuvuduko mu jisho no gutuma iyi ndwara irushaho kuba mibi. Mu buryo nk'ubwo, niba ufite indwara ikomeye y'impyiko cyangwa umwijima, muganga wawe azagomba gusuzuma izindi miti.

Izindi ndwara zishobora kukubuza gufata disopyramide zirimo:

• Myasthenia gravis (indwara yo kunanuka kw'imitsi)
• Ibibazo bikomeye byo guhumeka
• Prostate yagutse hamwe no kubura kw'inkari
• Umuvuduko muke w'amaraso ukabije
• Allergie izwi kuri disopyramide cyangwa imiti isa nayo

Kuba utwite no konsa bisaba kandi kubitekerezaho by'umwihariko, kuko disopyramide ishobora kwambuka placenta ikinjira mu mata. Muganga wawe azagereranya inyungu n'ibishobora guteza akaga kuri wowe no ku mwana wawe.

Amazina y'ubwoko bwa Disopyramide

Izina risanzwe rya disopyramide ni Norpace, iboneka mu buryo bwo kurekura ako kanya no kurekura gahoro gahoro. Ubwoko bwo kurekura gahoro gahoro bwitwa Norpace CR.

Ubwoko bwa disopyramide rusange buraboneka kandi burimo ibintu bisa n'ibyo mu bwoko bw'izina. Farumasi yawe ishobora gusimbuza ubwoko rusange keretse muganga wawe asabye by'umwihariko izina ry'ubwoko.

Uko wakwakira ubwoko bw'izina cyangwa ubwoko rusange, umuti ukora kimwe. Imiti rusange igomba guhura n'ubuziranenge bukomeye n'amabwiriza y'imikorere kimwe n'imiti y'izina.

Izindi miti isimbura Disopyramide

Niba disopyramide itagukwiriye cyangwa idakora neza, muganga wawe afite indi miti myinshi yo gusuzuma. Guhitamo biterwa n'ubwoko bwihariye bwa arrhythmia n'ubuzima bwawe muri rusange.

Izindi nzego za mbere za antiarrhythmics zirimo quinidine na procainamide, zikora kimwe na disopyramide ariko zishobora kugira ingaruka zitandukanye. Muganga wawe ashobora kugerageza kimwe muri ibi niba utabasha kwihanganira disopyramide.

Antiarrhythmics zo mu kiciro cya gatatu nka amiodarone cyangwa sotalol rimwe na rimwe zikoreshwa nk'izindi nzira, cyane cyane kubera indwara ziteje ubuzima bw'akaga. Iyi miti ikora mu buryo butandukanye ariko irashobora kugira akamaro kanini kubera indwara zimwe na zimwe z'umutima.

Kubera ibibazo bimwe na bimwe, beta-blockers cyangwa calcium channel blockers birashobora kuba izindi nzira zikwiye. Iyi miti akenshi yihanganirwa neza kandi irashobora kugira akamaro kubera ubwoko bumwe na bumwe bwa arrhythmias.

Ubuvuzi butari ubw'imiti nka catheter ablation, implantable cardioverter defibrillators (ICDs), cyangwa pacemakers birashobora kandi kuzirikwa bitewe n'uko ubuzima bwawe bumeze.

Ese Disopyramide iruta Quinidine?

Disopyramide na quinidine ni antiarrhythmics zo mu kiciro cya IA zikora mu buryo bumwe, ariko zifite itandukaniro rikomeye rituma imwe ikwiriye kurusha iyindi kubera abantu bamwe.

Disopyramide ikunda kugira ingaruka nke zo mu gifu kurusha quinidine, akenshi itera isesemi, kuruka, na diari. Niba waragize ibibazo byo mu gifu na quinidine, disopyramide irashobora kwihanganirwa neza.

Ariko, disopyramide ifite imbaraga zikomeye za anticholinergic, bivuze ko ushobora kurushaho kugira umunwa wumye, amaso atareba neza, no guhagarika inkari. Quinidine muri rusange iruta niba ukunda ubwo bwoko bw'ingaruka.

Kubera abarwayi bafite umutima udakora neza, imiti yombi isaba gukurikiranwa neza, ariko muganga wawe azatekereza ibyago byawe bwite mugihe uhitamo hagati yabo. Nta na kimwe kiruta muri rusange, kuko guhitamo neza biterwa n'ubuzima bwawe bwihariye bw'ubuvuzi n'uburyo wihanganira imiti yose.

Ibikunze Kubazwa Kuri Disopyramide

Ese Disopyramide irakwiriye kubera diyabete?

Disopyramide ishobora kugira ingaruka ku isukari yo mu maraso, cyane cyane itera hypoglycemia (isukari yo mu maraso iri hasi). Niba urwaye diyabete, muganga wawe azagenzura isukari yo mu maraso yawe cyane iyo utangiye gufata uyu muti.

Uyu muti ushobora guhisha ibimenyetso bimwe byo kugabanuka k'isukari yo mu maraso, nk'umutima utera vuba, bigatuma bigorana kumenya igihe isukari yawe yo mu maraso igabanutse. Genzura isukari yawe yo mu maraso buri gihe kandi umenye ibindi bimenyetso bya hypoglycemia nk'ibyuya, urujijo, cyangwa guhinda umushyitsi.

Imiti yawe ya diyabete ishobora gukenera guhindurwa mugihe ufata disopyramide. Korana cyane na muganga wawe w'umutima na endocrinologist kugirango wemeze ko indwara yawe y'umutima na diyabete byombi bikorwa neza.

Nkwiriye gukora iki niba mfashe disopyramide nyinshi ku buryo butunguranye?

Niba ufata disopyramide nyinshi ku buryo butunguranye kuruta uko byategetswe, vugana na muganga wawe ako kanya cyangwa uhamagare abaganga b'uburozi. Gufata nyinshi cyane bishobora gutera ibibazo bikomeye by'umutima, kugabanuka gukabije kw'umuvuduko w'amaraso, cyangwa izindi ngorane ziteje akaga.

Ntugategereze ngo urebe niba wumva umeze neza. Ibimenyetso byo kurenza urugero birimo isereri rikomeye, guta ubwenge, guhumeka bigoye, cyangwa impinduka mu mutima wawe. Ibi bishobora guteza akaga kandi bisaba ubufasha bwihuse bw'abaganga.

Niba bishoboka, zana icupa ry'umuti hamwe nawe mu cyumba cy'abarwayi kugirango abaganga babone neza icyo wafashe n'ingano yacyo. Igihe ni ingenzi mugukira kurenza urugero rw'imiti.

Nkwiriye gukora iki niba nciwe urugero rwa disopyramide?

Niba ucikanwe urugero rwa disopyramide, ifate ako kanya wibuka, keretse igihe cyegereje urugero rwawe ruteganyijwe. Muricyo gihe, reka urugero rwarucitse ukomeze gahunda yawe isanzwe.

Ntuzigere ufata urugero ebyiri icyarimwe kugirango usimbure urugero rwarucitse, kuko ibi bishobora gutera ingaruka ziteje akaga. Niba ufata ubwoko burekura buhoro, ibi ni ingenzi cyane kuko kwikuba kabiri bishobora kurekura imiti nyinshi icyarimwe.

Niba ukunda kwibagirwa imiti, shyiraho ibyibutsa kuri telefoni yawe cyangwa ukoreshe agasanduku kabugenewe. Kugumana urugero rwawo mu maraso buri gihe ni ingenzi kugira ngo ugabanye umuvuduko w'umutima wawe neza.

Ni ryari nshobora kureka gufata Disopyramide?

Reka gufata disopyramide gusa igihe muganga wawe akubwiye ko byemewe. Guhagarika ako kanya bishobora gutuma ibibazo by'umuvuduko w'umutima wawe bisubira, rimwe na rimwe bikaba bikomeye kurusha mbere.

Muganga wawe azasuzuma ibintu bitandukanye mbere yo guhagarika umuti, harimo uburyo umuvuduko w'umutima wawe wagenzurwaga neza, niba uburwayi bwawe bwateye imbere, kandi niba hari izindi miti ihari.

Igihe kigeze cyo guhagarika, muganga wawe azagabanya urugero rwawo buhoro buhoro mu minsi mike cyangwa mu byumweru. Ubu buryo bufasha kwirinda ibibazo by'umuvuduko w'umutima kandi bugaha umutima wawe umwanya wo kumenyera gukora udafite umuti.

Nshobora kunywa inzoga nkanwa Disopyramide?

Ni byiza kugabanya cyangwa kwirinda inzoga mugihe ufata disopyramide, cyane cyane niba ufata uburyo bwo kuyifata buhoro buhoro. Inzoga ishobora kubangamira uburyo umuti winjizwa kandi ishobora kongera ibyago byo kugira ingaruka zirimo isereri cyangwa umuvuduko w'amaraso uri hasi.

Inzoga kandi ishobora kugira ingaruka ku muvuduko w'umutima wawe ku giti cyawe, bishobora gukora ku buryo butandukanye n'inyungu z'umuti wawe. Niba uhisemo kunywa rimwe na rimwe, bikore mu rugero kandi ubivugane na muganga wawe.

Witondere cyane inzoga niba urwaye diyabete, kuko guhuza inzoga na disopyramide bishobora kongera ibyago byo kugira ibibazo by'isukari iri hasi mu maraso.