Icyo Edoxaban ari cyo: Ibyo ikoreshwa, urugero rwo gufata, ingaruka zayo n'ibindi

Edoxaban ni umuti wandikirwa n'abaganga ugabanya amaraso ufasha kwirinda ko amaraso avurirana mu mubiri wawe. Uyu muti ubarizwa mu cyiciro gishya cy'imiti igabanya amaraso yitwa direct oral anticoagulants (DOACs) ikora ibyo ikingira poroteyine yihariye ituma amaraso avurirana mu maraso yawe. Uyu muti akenshi wandikirwa abantu bafite atrial fibrillation cyangwa abafite amaraso yavuriranye mu maguru cyangwa mu muhogo.

Icyo Edoxaban ari cyo?

Edoxaban ni umuti unyobwa ugabanya amaraso utuma amaraso yawe atavurirana byoroshye. Wumve nk'umurinzi urinda amaraso yawe kugenda neza mu miyoboro yawe atavurirana. Bitandukanye n'imiti ishaje igabanya amaraso nka warfarin, edoxaban ikora neza kandi ntisaba ibizamini by'amaraso bya kenshi kugira ngo igenzurwe ingaruka zayo.

Uyu muti wihariye ugamije Factor Xa, poroteyine y'ingenzi mu mikorere y'amaraso yawe. Mu gukinga iyi poroteyine, edoxaban ifasha kugumana uburinganire bukwiye hagati yo kwirinda amaraso avurirana kandi ikemerera amaraso gusama neza igihe wakomeretse.

Edoxaban ikoreshwa mu iki?

Edoxaban ivura kandi ikarinda indwara nyinshi zikomeye ziterwa n'amaraso avurirana. Muganga wawe ashobora kukwandikira uyu muti niba ufite atrial fibrillation, indwara yo mu mutima ituma urugero rwa stroke ruzamuka. Ikoreshwa kandi mu kuvura deep vein thrombosis (amaraso avurirana mu miyoboro y'amaguru) na pulmonary embolism (amaraso avurirana mu miyoboro y'ibihaha).

Abantu bafite atrial fibrillation bahura n'amahirwe menshi yo kurwara stroke kuko umutima wabo utagenda neza bishobora gutuma amaraso yegerana akavurirana. Edoxaban ifasha kugabanya iyi stroke ikoreshwa mu kugumisha amaraso agenda neza. Ku bantu basanzwe barwaye amaraso avurirana, uyu muti ubabuza kurwara andi kandi ufasha umubiri wawe gusenyera amaraso yavuriranye mu buryo busanzwe.

Mu buryo butajegajega, abaganga bashobora kwandikira edoxaban kubera izindi ndwara zifitanye isano no kuvura amaraso cyangwa nk'urukingo mbere yo kubagwa. Muganga wawe azemeza niba edoxaban ikwiriye imiterere yawe yihariye hashingiwe ku mateka yawe y'ubuvuzi n'ibintu bigushyira mu kaga.

Edoxaban ikora ite?

Edoxaban ikora ibuza Factor Xa, urugero rwingenzi mu kuvura amaraso yawe. Uru rugero rukora nk'umukinnyi w'ingenzi mu gikorwa cy'urukurikirane rutuma amaraso avura. Mu kubuza Factor Xa, edoxaban ihagarika iyi nzira mbere yuko amaraso avura neza.

Uyu muti ufatwa nk'ufite imbaraga ziringaniye mu miti ivura amaraso. Irusha imbaraga aspirine ariko muri rusange itera ibyago bike byo kuva amaraso kurusha izindi anticoagulants. Ingaruka za edoxaban ziragaragara kandi zihamye, bivuze ko muganga wawe ashobora kwandika urugero rusanzwe atagombye kuruhindura hashingiwe ku bizami by'amaraso bihoraho.

Umuti utangira gukora mu masaha make nyuma yo kuwufata, kandi ingaruka zawo zimara hafi amasaha 24. Iyi ngengabihe igaragara bituma byoroha kuyicunga ugereranije n'imiti ivura amaraso ya kera yari ifite ingaruka zitandukanye.

Nkwiriye gufata gute Edoxaban?

Fata edoxaban nk'uko muganga wawe abitegeka, akenshi rimwe ku munsi hamwe n'ibiryo cyangwa nta biryo. Urashobora kuyifata n'amazi, amata, cyangwa umutobe - ibiryo ntibigira ingaruka zigaragara ku buryo umubiri wawe wunguka umuti. Abantu benshi basanga bifasha gufata edoxaban ku gihe kimwe buri munsi kugirango bagumane urwego rwo mu maraso.

Ntabwo ukeneye gukurikiza ibyo kurya byihariye mugihe ufata edoxaban, bitandukanye na warfarin. Ariko, ni byiza kwirinda kunywa inzoga nyinshi kuko bishobora kongera ibyago byo kuva amaraso. Niba ugira ikibazo cyo kumira ibinini, urashobora gukanda ibinini bya edoxaban ukabivanga n'amazi cyangwa applesauce, ariko banza ubaze umufarimasi.

Gerageza gushyiraho gahunda yo gufata imiti yawe. Abantu benshi bayifata bafungura cyangwa bafata amafunguro ya nimugoroba kugira ngo bibafashe kwibuka urugero rwabo rwa buri munsi. Gushyiraho umwanya wo kwibutswa kuri terefone na byo birashobora gufasha kwirinda gucikanwa n'imiti.

Nzamara Igihe Kingana Nde Ndafata Edoxaban?

Igihe cyo kuvurwa na edoxaban giterwa n'uburwayi bwawe bwihariye n'ibintu bigushyira mu kaga. Kubera atrial fibrillation, birashoboka ko uzakenera kuvurwa igihe kirekire kugira ngo urinde buri gihe ingaruka z'umutima. Kubera amaraso mu maguru yawe cyangwa mu bihaha, kuvurwa mubisanzwe bifata amezi atatu kugeza kuri atandatu, nubwo abantu bamwe bashobora gukenera kuvurwa igihe kirekire.

Muganga wawe azagenzura buri gihe niba ugikeneye edoxaban bitewe n'uburwayi bwawe, ibyago byo kuva amaraso, n'ubuzima bwawe muri rusange. Abantu bamwe bafite ibintu bikomeje kubashyira mu kaga bashobora gukenera kuvurwa ubuzima bwabo bwose, mu gihe abandi bashobora guhagarara nyuma yuko ibyago byabo byo gupfuka amaraso bigabanuka. Ntukigere uhagarika gufata edoxaban ako kanya utabanje kubaza muganga wawe, kuko ibi bishobora kongera ibyago byawe byo gupfuka amaraso bikomeye.

Niba waragize amaraso menshi yapfukanye cyangwa ufite uburwayi runaka bwo mu bwoko bw'imiryango, muganga wawe ashobora kugusaba kuvurwa igihe kirekire kurenza igihe gisanzwe. Bazagereranya inyungu zo kwirinda gupfuka amaraso n'ibyago bishoboka byo kuvurwa igihe kirekire.

Ni Iyihe Ngaruka Ziterwa na Edoxaban?

Kimwe n'ibindi byose bituma amaraso ataguma, ingaruka nyamukuru ya edoxaban ni ukwiyongera kw'ibyago byo kuva amaraso. Abantu benshi bafata neza uyu muti, ariko ni ngombwa kumenya icyo ugomba kwitaho. Ingaruka zisanzwe zikunda kuba nto kandi zishobora gucungwa neza hakoreshejwe ubugenzuzi bukwiye.

Dore ingaruka zisanzwe ushobora guhura nazo:

• Gukomereka byoroshye cyangwa ibikomere bigaragara nta mpamvu igaragara
• Kuva amaraso make ku bikomere bitinda guhagarara
• Gusama amazuru rimwe na rimwe
• Iminsi y'imihango ikomeye ku bagore
• Uburibwe buke mu gifu cyangwa isesemi
• Urugero cyangwa umutwe

Ibi bimenyetso bisanzwe bikunze gukira uko umubiri wawe ukimenyera umuti. Abantu benshi bakomeza kuvurwa nta bibazo bikomeye.

Ingaruka zikomeye ziraboneka gake ariko zisaba ubufasha bwihuse bw'abaganga. Izi zikubiyemo ibimenyetso byo kuva amaraso menshi bishobora gushyira ubuzima mu kaga:

• Umutwe ukabije cyangwa urujijo (bishobora guterwa no kuva amaraso mu bwonko)
• Kuruka amaraso cyangwa ibintu bisa n'ubutaka bw'ikawa
• Imyanda yirabura, isa na lisansi cyangwa amaraso atukura cyane mu myanda
• Umunaniro udasanzwe cyangwa kugwa igihumure
• Urubavu rukabije
• Kubura umwuka cyangwa kuribwa mu gituza

Niba ubonye kimwe muri ibi bimenyetso bikomeye, jya kwa muganga ako kanya. Nubwo biba gake, izi ngorane zisaba kuvurwa vuba kugira ngo hirindwe ingaruka zikomeye.

Ni bande batagomba gufata Edoxaban?

Abantu bamwe ntibagomba gufata edoxaban kubera ibyago byo kuva amaraso cyangwa izindi ndwara. Muganga wawe azasuzuma neza amateka yawe mbere yo kugutera uyu muti. Abantu bafite indwara ziva amaraso cyangwa ibihe byo kuva amaraso menshi ntibakunze gukoresha edoxaban mu buryo bwizewe.

Dore ibintu bishobora gutuma utafata edoxaban:

• Kuva amaraso imbere cyangwa kuva amaraso menshi vuba aha
• Indwara zikomeye z'impyiko cyangwa kunanirwa kw'impyiko
• Valves z'umutima zikora mu buryo bwa mekaniki
• Gusama cyangwa konsa
• Indwara zikomeye z'umwijima
• Allergie izwi kuri edoxaban cyangwa imiti isa nayo

Muganga wawe azanatekereza ku bintu bigushyira mu kaga ko kuva amaraso mbere yo kugutera edoxaban. Ibi bishobora kuba amateka ya za nyinshi, kubagwa vuba aha, cyangwa ibintu byongera ibyago byo kuva amaraso.

Abantu bamwe bakeneye gukurikiranwa byihariye cyangwa guhindura urugero rw'umuti aho kwirinda umuti rwose. Umuganga wawe azagena uburyo bwizewe bushingiye ku miterere yawe bwite n'ibyo umubiri wawe ukeneye.

Amazina y'ubwoko bwa Edoxaban

Edoxaban iboneka ku izina rya Savaysa muri Leta Zunze Ubumwe z'Amerika. Mu bindi bihugu, ishobora kugurishwa ku mazina atandukanye y'ubucuruzi nka Lixiana. Umuti nyirizina uracyari umwe uko byagenda kose ku izina ry'ubucuruzi.

Imiti ya edoxaban ikorwa mu buryo rusange irimo kuboneka mu turere tumwe na tumwe, bishobora gutuma igabanya ikiguzi. Ariko, buri gihe jya inama na muganga wawe cyangwa umufarumasiti mbere yo guhindura hagati y'imiti y'ubucuruzi n'iy'uburyo rusange kugira ngo wemeze ko uvurwa neza.

Izindi miti isimbura Edoxaban

Izindi miti myinshi igabanya amaraso ishobora gusimbura edoxaban niba itagukwiriye. Izindi miti igabanya amaraso ikoreshwa mu kanwa (DOACs) zirimo rivaroxaban (Xarelto), apixaban (Eliquis), na dabigatran (Pradaxa). Buri imwe ifite imiterere itandukanye gato n'igihe cyo kuyifata.

Warfarin iracyari amahitamo, cyane cyane ku bantu bafite imitsi y'umutima ikora mu buryo bwa mekaniki cyangwa indwara zikomeye z'impyiko. N'ubwo warfarin isaba gukurikiranwa amaraso buri gihe, imaze imyaka myinshi ikoreshwa mu buryo bwizewe kandi ifite imiti ivura ibibazo by'amaraso mu gihe cy'impanuka.

Ku bantu bamwe, imiti igabanya ibice by'amaraso nka aspirine cyangwa clopidogrel ishobora kuba indi miti ikwiriye, nubwo muri rusange idakora neza mu gukumira amaraso mu gihe cy'umutima udakora neza. Muganga wawe azagufasha guhitamo uburyo bwiza bushingiye ku burwayi bwawe bwihariye n'ibintu bigushyira mu kaga.

Ese Edoxaban iruta Warfarin?

Edoxaban itanga inyungu nyinshi kurusha warfarin, nubwo imiti yombi ikora neza mu gukumira amaraso. Edoxaban ntisaba ibizamini by'amaraso buri gihe kugira ngo igenzure ingaruka zayo, bituma bikorwa neza ku bantu benshi. Ifite kandi imikoranire mike n'ibiryo n'indi miti ugereranyije na warfarin.

Ubushakashatsi bwerekana ko edoxaban ifite ubushobozi bungana na warfarin mu gukumira indwara ziterwa n'umutima mu bantu bafite atrial fibrillation. Irashobora gutera amaraso make mu bwonko, ikaba ari imwe mu ngorane zikomeye ziterwa n'imiti ituma amaraso atavura. Ariko, edoxaban ubu ntigira umuti wihariye, mu gihe warfarin ishobora guhagarikwa na vitamine K cyangwa indi miti.

Gu hitamo hagati ya edoxaban na warfarin biterwa n'imiterere yawe bwite. Abantu bakunda kugenda cyane, bafite gahunda zihuzagurika, cyangwa bagorwa no gukurikiza ibyo kurya bya warfarin bakunda cyane edoxaban. Ariko, warfarin irashobora kuba nziza ku bantu bafite indwara zimwe na zimwe z'imitsi y'umutima cyangwa indwara zikomeye z'impyiko.

Ibikunze Kubazwa Kuri Edoxaban

Ese Edoxaban irakwiriye ku bantu barwaye indwara z'impyiko?

Edoxaban irashobora gukoreshwa ku bantu bafite indwara zoroheje cyangwa ziciriritse z'impyiko, ariko guhindura urugero rw'umuti bikunze kuba ngombwa. Muganga wawe azapima imikorere y'impyiko zawe mbere yo gutangira kuvurwa kandi azajya abikurikirana buri gihe. Abantu bafite indwara zikomeye z'impyiko cyangwa kunanirwa kw'impyiko mubisanzwe ntibashobora gukoresha edoxaban mu buryo bwizewe.

Niba imikorere y'impyiko zawe ihindutse mugihe ukoresha edoxaban, muganga wawe ashobora gukenera guhindura urugero rw'umuti cyangwa akaguherereza undi muti. Ibizamini by'amaraso bya buri gihe bifasha kumenya neza ko umuti ukomeza kuba mwiza kandi ukora neza ku miterere yawe.

Nkwiriye gukora iki niba nanyweye edoxaban nyinshi bitunguranye?

Niba unyweye edoxaban nyinshi bitunguranye, vugana na muganga wawe cyangwa ikigo gishinzwe kugenzura uburozi ako kanya. Kunywa nyinshi byongera cyane ibyago byo kuva amaraso. Ntukagerageze kwishyura usimbuka urugero rwawe rukurikira, kuko ibi bishobora kongera ibyago byawe byo kuvura.

Reba ibimenyetso byo kuva amaraso nk'uburibwe budasanzwe, amazuru ava amaraso, cyangwa gushyira amaraso mu nshyi. Shakisha ubufasha bw'ubuvuzi bwihutirwa niba ubonye kubabara umutwe bikabije, kuruka amaraso, cyangwa ibindi bimenyetso byo kuva amaraso bikomeye. Gira urupapuro rw'umuti hamwe nawe mugihe ushakisha ubufasha bw'ubuvuzi.

Nkwiriye gukora iki niba nirengagije urugero rwa edoxaban?

Niba wibagiwe gufata urugero rwa edoxaban, rufate uko wibukije ako kanya kuri uwo munsi. Niba byageze ku munsi ukurikira, reka urugero wibagiwe, maze ufate urugero rwawe rusanzwe ku gihe cyarwo. Ntukigere ufata urugero ebyiri icyarimwe kugira ngo usimbure urugero wibagiwe.

Kutagera gufata urugero rimwe na rimwe ntibisanzwe guteza ibibazo ako kanya, ariko gerageza gufata imiti yawe buri munsi kugira ngo ubashe kwirinda neza. Gushyiraho ibyibutso kuri terefone yawe cyangwa gukoresha agasanduku k'imiti birashobora kugufasha kwibuka imiti yawe.

Ni ryari nshobora kureka gufata Edoxaban?

Ntuzigere ureka gufata edoxaban utabanje kubaza muganga wawe. Guhagarika ako kanya bishobora kongera ibyago byo kuvurwa amaraso akomeye mu minsi mike. Muganga wawe azagena igihe cyiza cyo guhagarika bitewe n'uburwayi bwawe n'ibintu byongera ibyago byo kuvurwa amaraso.

Ku bantu bafite atrial fibrillation, guhagarika edoxaban ntibisanzwe byemewe keretse ibyago byo kuva amaraso birusha imbaraga inyungu zo kwirinda stroke. Abavurwa kubera kuvurwa amaraso bashobora kureka nyuma yo kurangiza urugendo rwabo rwanditswe, akenshi amezi atatu kugeza kuri atandatu.

Nshobora kunywa inzoga nkanwa edoxaban?

Urashobora kunywa inzoga mu rugero ruto nkanwa edoxaban, ariko kunywa inzoga nyinshi byongera ibyago byo kuva amaraso. Garagaza inzoga ntirenze kimwe ku munsi ku bagore na kabiri ku munsi ku bagabo. Kunywa inzoga nyinshi cyangwa gukoresha inzoga buri gihe bishobora guteza akaga hamwe n'umuti uwo ari wo wose utuma amaraso atavura.

Niba ufite impungenge ku bijyanye no gukoresha inzoga cyangwa ufite amateka y'ibibazo by'inzoga, ganira ibi na muganga wawe. Bashobora kugufasha gusobanukirwa uburyo bwiza bwo gukoresha nkanwa edoxaban.